JP2022501429A5 - - Google Patents
Info
- Publication number
- JP2022501429A5 JP2022501429A5 JP2021539486A JP2021539486A JP2022501429A5 JP 2022501429 A5 JP2022501429 A5 JP 2022501429A5 JP 2021539486 A JP2021539486 A JP 2021539486A JP 2021539486 A JP2021539486 A JP 2021539486A JP 2022501429 A5 JP2022501429 A5 JP 2022501429A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- alkyl
- cycloalkyl
- pharmaceutically acceptable
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024227127A JP2025066704A (ja) | 2018-09-18 | 2024-12-24 | 特定の白血病を治療するための化合物 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862733029P | 2018-09-18 | 2018-09-18 | |
| US62/733,029 | 2018-09-18 | ||
| US201962816637P | 2019-03-11 | 2019-03-11 | |
| US62/816,637 | 2019-03-11 | ||
| US201962889929P | 2019-08-21 | 2019-08-21 | |
| US62/889,929 | 2019-08-21 | ||
| PCT/US2019/051567 WO2020061086A2 (en) | 2018-09-18 | 2019-09-17 | Compounds for treating certain leukemias |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024227127A Division JP2025066704A (ja) | 2018-09-18 | 2024-12-24 | 特定の白血病を治療するための化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022501429A JP2022501429A (ja) | 2022-01-06 |
| JP2022501429A5 true JP2022501429A5 (enExample) | 2022-09-27 |
| JP7611832B2 JP7611832B2 (ja) | 2025-01-10 |
Family
ID=69774840
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021539486A Active JP7611832B2 (ja) | 2018-09-18 | 2019-09-17 | 特定の白血病を治療するための化合物 |
| JP2024227127A Pending JP2025066704A (ja) | 2018-09-18 | 2024-12-24 | 特定の白血病を治療するための化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024227127A Pending JP2025066704A (ja) | 2018-09-18 | 2024-12-24 | 特定の白血病を治療するための化合物 |
Country Status (19)
| Country | Link |
|---|---|
| US (4) | US10889571B2 (enExample) |
| EP (1) | EP3852745A4 (enExample) |
| JP (2) | JP7611832B2 (enExample) |
| KR (2) | KR20210061377A (enExample) |
| CN (3) | CN115448908B (enExample) |
| AU (2) | AU2019342102C1 (enExample) |
| BR (1) | BR112021004051A2 (enExample) |
| CA (1) | CA3110576A1 (enExample) |
| CL (1) | CL2021000637A1 (enExample) |
| CO (1) | CO2021004704A2 (enExample) |
| IL (2) | IL281427B2 (enExample) |
| MA (1) | MA53664A (enExample) |
| MX (2) | MX2021003093A (enExample) |
| NZ (1) | NZ773110A (enExample) |
| PE (2) | PE20211644A1 (enExample) |
| SG (1) | SG11202102367TA (enExample) |
| TW (1) | TWI826525B (enExample) |
| WO (1) | WO2020061086A2 (enExample) |
| ZA (1) | ZA202101304B (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ773110A (en) | 2018-09-18 | 2024-11-29 | Terns Inc | Compounds for treating certain leukemias |
| LT3860998T (lt) | 2018-10-05 | 2024-06-25 | Annapurna Bio Inc. | Junginiai ir kompozicijos, skirti gydyti būkles, susijusias su apj receptoriaus aktyvumu |
| CN121081472A (zh) | 2018-12-13 | 2025-12-09 | 拓臻股份有限公司 | 一种THRβ受体激动剂化合物及其制备方法和用途 |
| BR112021017756A2 (pt) | 2019-03-11 | 2021-11-16 | Inflarx Gmbh | Piperidinila bicíclica fundida e compostos relacionados como moduladores do receptor c5a |
| EP3947369A4 (en) * | 2019-07-29 | 2022-10-05 | Ascentage Pharma (Suzhou) Co., Ltd. | HETEROCYCLIC COMPOUNDS AS BCR-ABL INHIBITORS |
| CA3154488A1 (en) | 2019-08-23 | 2021-03-04 | Terns Pharmaceuticals, Inc. | Thyroid hormone receptor beta agonist compounds |
| CA3154391A1 (en) | 2019-09-12 | 2021-03-18 | Terns Pharmaceuticals, Inc. | Thyroid hormone receptor beta agonist compounds |
| JP2024510935A (ja) * | 2021-03-03 | 2024-03-12 | ターンズ・ファーマシューティカルズ・インコーポレイテッド | 甲状腺ホルモン受容体ベータアゴニスト化合物 |
| CN116375650B (zh) * | 2022-12-30 | 2025-08-05 | 浙江美诺华药物化学有限公司 | 一种替戈拉生中间体的制备方法 |
| PE20252787A1 (es) | 2023-04-07 | 2025-12-22 | Terns Pharmaceuticals Inc | Combinacion que comprende un agonista de thr-beta y un agonista de glp-1r para su uso en el tratamiento de un trastorno hepatico o una enfermedad cardiometabolica |
| TW202525293A (zh) | 2023-08-31 | 2025-07-01 | 美商拓臻製藥公司 | 用於治療癌症之組合 |
| WO2025226724A1 (en) | 2024-04-23 | 2025-10-30 | Terns Pharmaceuticals, Inc. | Bcr-abl1 inhibitors for use in treating cancer |
| CN120842151A (zh) * | 2024-04-26 | 2025-10-28 | 北京英飞智药科技有限公司 | 一种2-芳基苯并咪唑类化合物及其制备方法与应用 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA00011470A (es) | 1998-05-22 | 2002-10-17 | Avanir Pharmaceuticals | Analogos de bencimidazol como reguladores de la disminucion de ige. |
| SE0003476D0 (sv) | 2000-09-28 | 2000-09-28 | Astrazeneca Ab | Compounds |
| TW200304820A (en) * | 2002-03-25 | 2003-10-16 | Avanir Pharmaceuticals | Use of benzimidazole analogs in the treatment of cell proliferation |
| AR053364A1 (es) * | 2005-04-20 | 2007-05-02 | Smithkline Beecham | Compuesto de 1h-imidazo 84,5-c) piridin -2- ilo, composicion farmaceutica que lo comprende, proceso para prepararla y su uso para preparar un medicamento para tratamiento de cancer o artritis |
| CN101553468A (zh) * | 2006-10-18 | 2009-10-07 | 诺瓦提斯公司 | 有机化合物 |
| PE20080888A1 (es) | 2006-10-18 | 2008-08-26 | Novartis Ag | COMPUESTOS HETEROCICLICOS COMO INHIBIDORES DE LA ACIL-TRANSFERASA DE ACIL-CoA-DIACIL-GLICEROL 1 (DGAT1) |
| GB0800035D0 (en) | 2008-01-02 | 2008-02-13 | Glaxo Group Ltd | Compounds |
| WO2013033093A1 (en) | 2011-08-29 | 2013-03-07 | Biocryst Pharmaceuticals, Inc. | Heterocyclic compounds as janus kinase inhibitors |
| ES2670601T3 (es) | 2012-05-15 | 2018-05-31 | Novartis Ag | Derivados de benzamida para la inhibición de la actividad de ABL1, ABL2 y BCR-ABL1 |
| KR20150008406A (ko) | 2012-05-15 | 2015-01-22 | 노파르티스 아게 | Abl1, abl2 및 bcr-abl1의 활성을 억제하기 위한 벤즈아미드 유도체 |
| MX357305B (es) | 2012-05-15 | 2018-07-04 | Novartis Ag | Compuestos y composiciones para inhibir la actividad de abl-1, abl-2, y bcr-abl1. |
| CA2874303C (en) | 2012-06-11 | 2020-10-13 | Ucb Biopharma Sprl | Tnf -alpha modulating benz imidazoles |
| CN103113355B (zh) | 2013-02-27 | 2014-08-13 | 无锡爱内特生物科技有限公司 | 一种Bcr/Abl酪氨酸激酶抑制剂及其制备方法和在治疗慢性粒细胞白血病中的应用 |
| GB201401086D0 (en) | 2014-01-23 | 2014-03-12 | Galapagos Nv | Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders |
| US9931342B2 (en) | 2016-02-02 | 2018-04-03 | Duke University | Compositions and methods for the treatment of cancer |
| CN109790144A (zh) | 2016-04-29 | 2019-05-21 | 爱仕达生物技术有限责任公司 | 新型杂环化合物作为酪氨酸激酶bcr-abl抑制剂 |
| JP6778833B2 (ja) | 2017-01-20 | 2020-11-04 | 深▲チェン▼市塔吉瑞生物医薬有限公司Ｓｈｅｎｚｈｅｎ ＴａｒｇｅｔＲｘ， Ｉｎｃ． | キナーゼ活性を抑制するための（ヘテロ）アリールアミド類化合物 |
| CN108602800B (zh) | 2017-01-20 | 2019-08-27 | 深圳市塔吉瑞生物医药有限公司 | 用于抑制蛋白激酶活性的(杂)芳基酰胺类化合物 |
| WO2018191146A1 (en) * | 2017-04-10 | 2018-10-18 | Navitor Pharmaceuticals, Inc. | Heteroaryl rheb inhibitors and uses thereof |
| US11649218B2 (en) | 2018-03-09 | 2023-05-16 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | C-Abl tyrosine kinase inhibitory compound embodiments and methods of making and using the same |
| NZ773110A (en) | 2018-09-18 | 2024-11-29 | Terns Inc | Compounds for treating certain leukemias |
| US20240262842A1 (en) | 2021-04-27 | 2024-08-08 | Merck Sharp & Dohme Llc | Small molecule inhibitors of kras g12c mutant |
| KR20240089224A (ko) | 2021-09-30 | 2024-06-20 | 장쑤 한서 파마슈티칼 그룹 캄파니 리미티드 | 4-원 융합 고리형 화합물 및 이의 제조방법 및 용도 |
| TW202502333A (zh) | 2023-03-30 | 2025-01-16 | 大陸商江蘇豪森藥業集團有限公司 | 四元稠環類化合物鹽晶型及其製備方法和應用 |
| TW202525293A (zh) | 2023-08-31 | 2025-07-01 | 美商拓臻製藥公司 | 用於治療癌症之組合 |
-
2019
- 2019-09-17 NZ NZ773110A patent/NZ773110A/en unknown
- 2019-09-17 CN CN202210969394.6A patent/CN115448908B/zh active Active
- 2019-09-17 US US16/573,860 patent/US10889571B2/en active Active
- 2019-09-17 TW TW108133432A patent/TWI826525B/zh active
- 2019-09-17 MX MX2021003093A patent/MX2021003093A/es unknown
- 2019-09-17 CA CA3110576A patent/CA3110576A1/en active Pending
- 2019-09-17 PE PE2021000343A patent/PE20211644A1/es unknown
- 2019-09-17 KR KR1020217011001A patent/KR20210061377A/ko not_active Abandoned
- 2019-09-17 IL IL281427A patent/IL281427B2/en unknown
- 2019-09-17 MA MA053664A patent/MA53664A/fr unknown
- 2019-09-17 KR KR1020267002852A patent/KR20260019669A/ko active Pending
- 2019-09-17 JP JP2021539486A patent/JP7611832B2/ja active Active
- 2019-09-17 AU AU2019342102A patent/AU2019342102C1/en active Active
- 2019-09-17 EP EP19862388.6A patent/EP3852745A4/en active Pending
- 2019-09-17 CN CN202210968772.9A patent/CN115215838B/zh active Active
- 2019-09-17 PE PE2025001942A patent/PE20252740A1/es unknown
- 2019-09-17 IL IL322515A patent/IL322515A/en unknown
- 2019-09-17 SG SG11202102367TA patent/SG11202102367TA/en unknown
- 2019-09-17 BR BR112021004051-0A patent/BR112021004051A2/pt unknown
- 2019-09-17 WO PCT/US2019/051567 patent/WO2020061086A2/en not_active Ceased
- 2019-09-17 CN CN201980060896.3A patent/CN112770745B/zh active Active
-
2021
- 2021-02-25 ZA ZA2021/01304A patent/ZA202101304B/en unknown
- 2021-03-16 MX MX2023007714A patent/MX2023007714A/es unknown
- 2021-03-16 CL CL2021000637A patent/CL2021000637A1/es unknown
- 2021-04-15 CO CONC2021/0004704A patent/CO2021004704A2/es unknown
-
2023
- 2023-06-22 US US18/339,516 patent/US12240835B2/en active Active
-
2024
- 2024-12-20 AU AU2024287115A patent/AU2024287115A1/en active Pending
- 2024-12-24 JP JP2024227127A patent/JP2025066704A/ja active Pending
-
2025
- 2025-01-30 US US19/041,557 patent/US20250276961A1/en active Pending
- 2025-03-06 US US19/072,824 patent/US12454524B2/en active Active
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