JP2022501428A5 - - Google Patents
Info
- Publication number
- JP2022501428A5 JP2022501428A5 JP2021539483A JP2021539483A JP2022501428A5 JP 2022501428 A5 JP2022501428 A5 JP 2022501428A5 JP 2021539483 A JP2021539483 A JP 2021539483A JP 2021539483 A JP2021539483 A JP 2021539483A JP 2022501428 A5 JP2022501428 A5 JP 2022501428A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amino acid
- acid sequence
- sequence shown
- hcdr3
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862732299P | 2018-09-17 | 2018-09-17 | |
| US201862732334P | 2018-09-17 | 2018-09-17 | |
| US62/732,334 | 2018-09-17 | ||
| US62/732,299 | 2018-09-17 | ||
| PCT/US2019/051529 WO2020061059A1 (en) | 2018-09-17 | 2019-09-17 | Anti-lilrb2 antibodies and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022501428A JP2022501428A (ja) | 2022-01-06 |
| JP2022501428A5 true JP2022501428A5 (enExample) | 2022-09-29 |
Family
ID=69888746
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021539483A Pending JP2022501428A (ja) | 2018-09-17 | 2019-09-17 | 抗ｌｉｌｒｂ２抗体およびその使用の方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US12157768B2 (enExample) |
| EP (1) | EP3852805A4 (enExample) |
| JP (1) | JP2022501428A (enExample) |
| KR (1) | KR20210108940A (enExample) |
| CN (1) | CN113543804A (enExample) |
| AU (1) | AU2019343131A1 (enExample) |
| CA (1) | CA3111862A1 (enExample) |
| WO (1) | WO2020061059A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI819024B (zh) | 2018-07-09 | 2023-10-21 | 美商戊瑞治療有限公司 | 結合至ｉｌｔ４的抗體 |
| EP4076521A4 (en) * | 2019-12-20 | 2024-01-24 | Merck Sharp & Dohme LLC | Methods for treating cancer using a combination of a pd-1 antagonist, an ilt4 antagonist, and chemotherapeutic agents |
| CN115956089A (zh) | 2020-05-04 | 2023-04-11 | 加利福尼亚大学董事会 | 抑制性抗enpp1抗体 |
| CN116710132A (zh) * | 2020-09-17 | 2023-09-05 | 默沙东有限责任公司 | 抗ilt4抗体或其与抗pd-1抗体的组合用于治疗癌症的给药方案 |
| EP3981789A1 (en) | 2020-10-12 | 2022-04-13 | Commissariat À L'Énergie Atomique Et Aux Énergies Alternatives | Anti-lilrb antibodies and uses thereof |
| JP7854991B2 (ja) * | 2020-10-21 | 2026-05-07 | イミューン－オーエヌシー セラピューティクス，インコーポレーテッド | 新規の抗ｌｉｌｒｂ２抗体および誘導体生成物 |
| AU2022233201A1 (en) * | 2021-03-11 | 2023-09-28 | University Health Network | Lilrb1 and lilrb2-binding molecules and uses therefor |
| WO2023279107A1 (en) * | 2021-07-01 | 2023-01-05 | Albert Einstein College Of Medicine | Compositions and methods for inhibiting the expression of tmigd2 |
| JP2025510232A (ja) * | 2022-03-29 | 2025-04-14 | エヌジーエム バイオファーマシューティカルス，インコーポレーテッド | Ｉｌｔ３及びｃｄ３結合剤及びその使用方法 |
| WO2023235706A1 (en) * | 2022-05-31 | 2023-12-07 | Ngm Biopharmaceuticals, Inc. | Combination therapies using ilt-binding agents and pd-1 inhibitors |
| CN116082504B (zh) * | 2022-06-28 | 2026-05-05 | 北京科诺信诚科技有限公司 | 靶向人lilrb2的纳米抗体及其应用 |
| CN116333128B (zh) * | 2022-06-28 | 2026-03-24 | 北京科诺信诚科技有限公司 | 靶向人lilrb2的纳米抗体及其应用 |
| CN119604531A (zh) * | 2022-07-29 | 2025-03-11 | 盛禾(中国)生物制药有限公司 | 一种抗ilt4的单域抗体及其应用 |
| IL319145A (en) * | 2022-08-22 | 2025-04-01 | Antengene Biologics Ltd | Novel anti-LILRB2 antibodies and their uses |
| WO2024051804A1 (zh) * | 2022-09-08 | 2024-03-14 | 江苏恒瑞医药股份有限公司 | 抗ilt4抗体及其医药用途 |
| KR20250090398A (ko) * | 2022-09-28 | 2025-06-19 | 스팍스 바이오사이언스 리미티드 | 백혈구 면역글로불린 유사 수용체 하위 패밀리 b 구성원 2(lilrb2)에 결합하는 항체 및 그 용도 |
| EP4491230A1 (en) * | 2023-07-14 | 2025-01-15 | iOmx Therapeutics AG | Cross-specific antigen binding proteins (abp) targeting leukocyte immunoglobulin-like receptor subfamily b1 (lilrb1) and lilrb2, combinations and uses thereof |
| AU2023410277A1 (en) * | 2022-12-23 | 2025-06-12 | Iomx Therapeutics Ag | Cross-specific antigen binding proteins (abp) targeting leukocyte immunoglobulin-like receptor subfamily b1 (lilrb1) and lilrb2, combinations and uses thereof |
| JP2026504928A (ja) * | 2023-01-20 | 2026-02-10 | ワシントン・ユニバーシティ | Ｌｉｌｒｂ４／ｉｌｔ３アンタゴニスト組成物およびその使用方法 |
| CN116789826A (zh) * | 2023-05-12 | 2023-09-22 | 南京师范大学 | 抗人lilrb2全人源单域抗体及其应用 |
| CN119176874A (zh) * | 2023-06-21 | 2024-12-24 | 康源博创生物科技(北京)有限公司 | 一种能够结合lilrb2的抗体或其抗原结合片段 |
| WO2025128822A1 (en) * | 2023-12-12 | 2025-06-19 | The Methodist Hospital | Lilrb3 modulators and methods of use thereof |
| GB202319149D0 (en) * | 2023-12-14 | 2024-01-31 | Kbio Holdings Ltd | Antibody |
| CN121299117B (zh) * | 2025-12-05 | 2026-03-27 | 中国农业科学院都市农业研究所 | 检测猪轮状病毒的试剂和纳米酶免疫层析试纸条及其应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2912068B1 (en) * | 2012-10-26 | 2019-06-19 | Deutsches Rheuma-Forschungszentrum Berlin | Bi-specific antibodies for cell-lineage-specific tnf-alpha neutralisation |
| JP6490574B2 (ja) * | 2013-02-28 | 2019-03-27 | 国立研究開発法人国立がん研究センター | 不溶性フィブリンに対する抗体 |
| EP2970373A1 (en) | 2013-03-12 | 2016-01-20 | The Board of Trustees of The Leland Stanford Junior University | Methods and compositions for inhibiting the effects of amyloid beta oligomers |
| CA2948871A1 (en) | 2014-05-22 | 2015-11-26 | Fred Hutchinson Cancer Research Center | Lilrb2 and notch-mediated expansion of hematopoietic precursor cells |
| US20160200815A1 (en) * | 2015-01-05 | 2016-07-14 | Jounce Therapeutics, Inc. | Antibodies that inhibit tim-3:lilrb2 interactions and uses thereof |
| CA3218106A1 (en) * | 2015-03-06 | 2016-09-15 | The Board Of Regents Of The University Of Texas System | Anti-lilrb antibodies and their use in detecting and treating cancer |
| US11359018B2 (en) * | 2016-11-18 | 2022-06-14 | Symphogen A/S | Anti-PD-1 antibodies and compositions |
| TWI796329B (zh) * | 2017-04-07 | 2023-03-21 | 美商默沙東有限責任公司 | 抗－ilt4抗體及抗原結合片段 |
-
2019
- 2019-09-17 US US17/276,324 patent/US12157768B2/en active Active
- 2019-09-17 AU AU2019343131A patent/AU2019343131A1/en not_active Abandoned
- 2019-09-17 CA CA3111862A patent/CA3111862A1/en active Pending
- 2019-09-17 CN CN201980075255.5A patent/CN113543804A/zh active Pending
- 2019-09-17 JP JP2021539483A patent/JP2022501428A/ja active Pending
- 2019-09-17 WO PCT/US2019/051529 patent/WO2020061059A1/en not_active Ceased
- 2019-09-17 KR KR1020217011459A patent/KR20210108940A/ko not_active Withdrawn
- 2019-09-17 EP EP19863793.6A patent/EP3852805A4/en not_active Withdrawn
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