|
US12419965B2
(en)
|
2018-10-01 |
2025-09-23 |
BioNTech SE |
RNA particles comprising polysarcosine
|
|
CN114127044A
(zh)
*
|
2019-04-25 |
2022-03-01 |
英特利亚治疗股份有限公司 |
可电离的胺类脂质和脂质纳米颗粒
|
|
CA3145913A1
(en)
|
2019-07-29 |
2021-02-04 |
James Everett Dahlman |
Nanomaterials containing constrained lipids and uses thereof
|
|
US12521451B2
(en)
|
2019-11-08 |
2026-01-13 |
Regeneron Pharmaceuticals, Inc. |
CRISPR and AAV strategies for x-linked juvenile retinoschisis therapy
|
|
IL294318A
(en)
|
2020-01-09 |
2022-08-01 |
Guide Therapeutics Llc |
Nanomaterials
|
|
IL297419B2
(en)
|
2020-04-22 |
2025-02-01 |
BioNTech SE |
Coronavirus vaccine
|
|
CA3181340A1
(en)
|
2020-04-28 |
2021-11-04 |
Intellia Therapeutics, Inc. |
Methods of in vitro cell delivery
|
|
EP4228658A4
(en)
|
2020-10-14 |
2025-02-19 |
George Mason Research Foundation, Inc. |
IONIZABLE LIPIDS AND METHODS FOR THE PRODUCTION AND USE THEREOF
|
|
WO2022101486A1
(en)
*
|
2020-11-16 |
2022-05-19 |
BioNTech SE |
Pharmaceutical compositions comprising particles and mrna and methods for preparing and storing the same
|
|
US20240041785A1
(en)
*
|
2020-11-16 |
2024-02-08 |
BioNTech SE |
Compositions and methods for stabilization of lipid nanoparticle mrna vaccines
|
|
CN117042758A
(zh)
*
|
2020-11-16 |
2023-11-10 |
生物技术欧洲股份公司 |
用于稳定化脂质纳米颗粒mRNA疫苗的组合物和方法
|
|
TW202237148A
(zh)
*
|
2020-11-16 |
2022-10-01 |
德商拜恩迪克公司 |
包含rna之lnp組合物以及製備、儲存及使用彼之方法
|
|
WO2022218503A1
(en)
*
|
2021-04-12 |
2022-10-20 |
BioNTech SE |
Lnp compositions comprising rna and methods for preparing, storing and using the same
|
|
CN116782889A
(zh)
*
|
2020-11-16 |
2023-09-19 |
生物技术欧洲股份公司 |
增强的制剂稳定性和改善的冻干工艺
|
|
IL303506A
(en)
|
2020-12-11 |
2023-08-01 |
Intellia Therapeutics Inc |
Polynucleotides, compositions, and methods for genome editing involving deamination
|
|
EP4262818A4
(en)
*
|
2020-12-21 |
2025-03-26 |
Beam Therapeutics Inc. |
NANOMATERIALS WITH CARBONATES
|
|
JP2024503976A
(ja)
*
|
2020-12-21 |
2024-01-30 |
ビーム セラピューティクス インク. |
アセタールを含むナノ材料
|
|
EP4262819A4
(en)
*
|
2020-12-21 |
2024-12-04 |
Beam Therapeutics Inc. |
NANOMATERIALS WITH ESTER-BOUND ACETALS
|
|
EP4281080A4
(en)
*
|
2021-01-20 |
2025-09-24 |
Beam Therapeutics Inc |
NANOMATERIALS COMPRISING A BIODEGRADABLE ELEMENT
|
|
CN116761888A
(zh)
|
2021-01-20 |
2023-09-15 |
比姆医疗股份有限公司 |
纳米材料
|
|
CN113993839B
(zh)
*
|
2021-02-05 |
2024-02-09 |
嘉晨西海(杭州)生物技术有限公司 |
一种可离子化脂质分子、其制备方法及其在制备脂质纳米颗粒中的应用
|
|
CN112961065B
(zh)
*
|
2021-02-05 |
2023-03-14 |
嘉晨西海(杭州)生物技术有限公司 |
一种可电离脂质分子及其制备方法及其在制备脂质纳米颗粒的应用
|
|
CN117510830A
(zh)
*
|
2021-04-08 |
2024-02-06 |
厦门赛诺邦格生物科技股份有限公司 |
一种聚乙二醇化脂质及其修饰的脂质体、含该脂质体的药物组合物及其制剂和应用
|
|
CN115197078B
(zh)
*
|
2021-04-08 |
2024-06-04 |
厦门赛诺邦格生物科技股份有限公司 |
一种聚乙二醇化脂质及其修饰的脂质体、含该脂质体的药物组合物及其制剂和应用
|
|
IL307740A
(en)
|
2021-04-17 |
2023-12-01 |
Intellia Therapeutics Inc |
DNA-dependent protein kinase inhibitors and their compositions and uses
|
|
KR20240017793A
(ko)
|
2021-04-17 |
2024-02-08 |
인텔리아 테라퓨틱스, 인크. |
지질 나노입자 조성물
|
|
EP4351651A1
(en)
*
|
2021-05-28 |
2024-04-17 |
Renagade Therapeutics Management Inc. |
Lipid nanoparticles and methods of use thereof
|
|
WO2022261292A1
(en)
|
2021-06-10 |
2022-12-15 |
Intellia Therapeutics, Inc. |
Modified guide rnas comprising an internal linker for gene editing
|
|
KR20240038705A
(ko)
*
|
2021-06-22 |
2024-03-25 |
인텔리아 테라퓨틱스, 인크. |
간 유전자의 생체 내 편집 방법
|
|
TW202328067A
(zh)
|
2021-09-14 |
2023-07-16 |
美商雷納嘉德醫療管理公司 |
環狀脂質及其使用方法
|
|
CN118317944A
(zh)
|
2021-09-14 |
2024-07-09 |
雷纳嘉德医疗管理公司 |
非环状脂质及其使用方法
|
|
US20250295755A1
(en)
|
2021-10-22 |
2025-09-25 |
Sail Biomedicines, Inc. |
Mrna vaccine composition
|
|
CA3237303A1
(en)
|
2021-11-03 |
2023-05-11 |
Intellia Therapeutics, Inc. |
Polynucleotides, compositions, and methods for genome editing
|
|
CA3238764A1
(en)
|
2021-11-23 |
2023-06-01 |
Siddharth Patel |
A bacteria-derived lipid composition and use thereof
|
|
US12186387B2
(en)
|
2021-11-29 |
2025-01-07 |
BioNTech SE |
Coronavirus vaccine
|
|
EP4452239A1
(en)
|
2021-12-20 |
2024-10-30 |
Sail Biomedicines, Inc. |
Compositions comprising mrna and lipid reconstructed plant messenger packs
|
|
TW202330457A
(zh)
*
|
2022-01-19 |
2023-08-01 |
大陸商蘇州艾博生物科技有限公司 |
脂質化合物和脂質奈米顆粒組合物
|
|
CN114874104B
(zh)
*
|
2022-04-29 |
2024-11-29 |
湖北英纳氏生物科技有限公司 |
阳离子脂质体SM-102及Lipid5的制备方法
|
|
WO2023222081A1
(zh)
|
2022-05-19 |
2023-11-23 |
仁景(苏州)生物科技有限公司 |
长链烷基酯胺类脂质化合物及其制备方法和在核酸递送方面的应用
|
|
CN119384498A
(zh)
|
2022-06-16 |
2025-01-28 |
因特利亚治疗公司 |
用于对细胞进行遗传修饰的方法和组合物
|
|
WO2024002985A1
(en)
|
2022-06-26 |
2024-01-04 |
BioNTech SE |
Coronavirus vaccine
|
|
CA3260437A1
(en)
|
2022-07-20 |
2024-01-25 |
Beam Therapeutics Inc. |
NANOMATERIALS INCLUDING TRIOLS
|
|
US20260035338A1
(en)
*
|
2022-10-13 |
2026-02-05 |
Shenzhen Shenxin Biotechnology Co., Ltd. |
Amino lipid compound and lipid nanoparticle for delivering bioactive ingredient
|
|
WO2024102434A1
(en)
|
2022-11-10 |
2024-05-16 |
Senda Biosciences, Inc. |
Rna compositions comprising lipid nanoparticles or lipid reconstructed natural messenger packs
|
|
EP4626600A1
(en)
*
|
2022-11-30 |
2025-10-08 |
Agency for Science, Technology and Research (A*STAR) |
Methods of synthesising ionisable lipids
|
|
EP4638783A2
(en)
|
2022-12-22 |
2025-10-29 |
Intellia Therapeutics, Inc. |
Methods for analyzing nucleic acid cargos of lipid nucleic acid assemblies
|
|
CN120418427A
(zh)
|
2022-12-23 |
2025-08-01 |
因特利亚治疗公司 |
用于基因组编辑的系统和方法
|
|
CN121057577A
(zh)
|
2023-01-27 |
2025-12-02 |
赛欧生物医药股份有限公司 |
经修饰的脂质组合物及其用途
|
|
WO2024220752A2
(en)
|
2023-04-19 |
2024-10-24 |
Sail Biomedicines, Inc. |
Rna therapeutic compositions
|
|
WO2024220712A2
(en)
|
2023-04-19 |
2024-10-24 |
Sail Biomedicines, Inc. |
Vaccine compositions
|
|
WO2024220625A1
(en)
|
2023-04-19 |
2024-10-24 |
Sail Biomedicines, Inc. |
Delivery of polynucleotides from lipid nanoparticles comprising rna and ionizable lipids
|
|
CN121039098A
(zh)
*
|
2023-04-28 |
2025-11-28 |
日东电工株式会社 |
脂质、包含其的药物组合物、和递送活性药物成分的方法
|
|
AU2024312860A1
(en)
*
|
2023-06-21 |
2026-01-22 |
Renagade Therapeutics Management Inc. |
Lipid nanoparticles comprising coding rna molecules for use in gene editing and as vaccines and therapeutic agents
|
|
WO2025000542A1
(en)
*
|
2023-06-30 |
2025-01-02 |
Shanghai Vitalgen Biopharma Co., Ltd. |
Ionizable cationic lipid compounds for delivery of biologically active agents
|
|
WO2025049481A1
(en)
|
2023-08-28 |
2025-03-06 |
Intellia Therapeutics, Inc. |
Methods of editing an hla-a gene in vitro
|
|
WO2025064401A1
(en)
|
2023-09-18 |
2025-03-27 |
Intellia Therapeutics, Inc. |
Nuclease resistant single stranded dna product for non-viral delivery to a cell and methods of production thereof
|
|
WO2025064396A1
(en)
|
2023-09-18 |
2025-03-27 |
Intellia Therapeutics, Inc. |
Nuclease resistant double stranded dna product for non-viral delivery to a cell and methods of production thereof
|
|
WO2025106915A1
(en)
|
2023-11-17 |
2025-05-22 |
Sail Biomedicines, Inc. |
Circular polyribonucleotides encoding glucagon-like peptide 1 (glp-1) and uses thereof
|
|
WO2025106930A1
(en)
|
2023-11-17 |
2025-05-22 |
Sail Biomedicines, Inc. |
Circular polyribonucleotides encoding glucagon-like peptide 2 (glp-2) and uses thereof
|
|
WO2025128871A2
(en)
|
2023-12-13 |
2025-06-19 |
Renagade Therapeutics Management Inc. |
Lipid nanoparticles comprising coding rna molecules for use in gene editing and as vaccines and therapeutic agents
|
|
WO2025137301A1
(en)
|
2023-12-20 |
2025-06-26 |
Intellia Therapeutics, Inc. |
Methods for rapid engineering of cells
|
|
CN118255678B
(zh)
*
|
2024-03-28 |
2024-12-24 |
荣灿生物医药技术(上海)有限公司 |
一种可电离脂质化合物及其应用
|
|
WO2025240946A1
(en)
|
2024-05-17 |
2025-11-20 |
Intellia Therapeutics, Inc. |
Lipid nanoparticles and lipid nanoparticle compositions
|
|
WO2026003582A2
(en)
|
2024-06-27 |
2026-01-02 |
Axelyf ehf. |
Lipids and lipid nanoparticles
|
|
WO2026035680A1
(en)
|
2024-08-06 |
2026-02-12 |
Kernal Biologics, Inc. |
Compositions and methods for delivery of agents
|