JP2022501055A5 - - Google Patents
Info
- Publication number
- JP2022501055A5 JP2022501055A5 JP2021517046A JP2021517046A JP2022501055A5 JP 2022501055 A5 JP2022501055 A5 JP 2022501055A5 JP 2021517046 A JP2021517046 A JP 2021517046A JP 2021517046 A JP2021517046 A JP 2021517046A JP 2022501055 A5 JP2022501055 A5 JP 2022501055A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- expression vector
- conjugated
- pharmaceutical composition
- vector according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862736834P | 2018-09-26 | 2018-09-26 | |
| US62/736,834 | 2018-09-26 | ||
| US201862747646P | 2018-10-18 | 2018-10-18 | |
| US62/747,646 | 2018-10-18 | ||
| US201962805793P | 2019-02-14 | 2019-02-14 | |
| US62/805,793 | 2019-02-14 | ||
| PCT/US2019/053260 WO2020069194A1 (en) | 2018-09-26 | 2019-09-26 | Methods and compositions for treating a premature stop codon-mediated disorder |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022501055A JP2022501055A (ja) | 2022-01-06 |
| JP2022501055A5 true JP2022501055A5 (https=) | 2022-10-04 |
Family
ID=69949797
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021517046A Pending JP2022501055A (ja) | 2018-09-26 | 2019-09-26 | 未成熟終止コドン媒介性障害を治療するための方法および組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20240050594A1 (https=) |
| EP (1) | EP3856253A4 (https=) |
| JP (1) | JP2022501055A (https=) |
| AU (1) | AU2019350869A1 (https=) |
| CA (1) | CA3114108A1 (https=) |
| WO (1) | WO2020069194A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102930465B1 (ko) | 2017-11-02 | 2026-02-25 | 더 위스타 인스티튜트 오브 아나토미 앤드 바이올로지 | ACE-tRNA를 이용한 유전 재할당을 통한 정지 코돈의 구조 방법 |
| MX2022012955A (es) | 2020-04-14 | 2023-02-23 | Flagship Pioneering Innovations Vi Llc | Composiciones de trem y usos de las mismas. |
| KR20230029685A (ko) * | 2020-05-29 | 2023-03-03 | 플래그쉽 파이어니어링 이노베이션스 브이아이, 엘엘씨 | Trem 조성물 및 이에 관련된 방법 |
| JP2024538097A (ja) * | 2021-10-13 | 2024-10-18 | フラッグシップ パイオニアリング イノベーションズ シックス，エルエルシー | Ｔｒｅｍ組成物及び使用方法 |
| EP4202045A1 (en) * | 2021-12-22 | 2023-06-28 | Universität Hamburg | Synthetic transfer rna with modified nucleotides |
| EP4442826A1 (en) | 2023-04-06 | 2024-10-09 | Universität Hamburg | Synthetic dna construct encoding transfer rna |
| EP4458967A1 (en) | 2023-05-02 | 2024-11-06 | Universität Hamburg | Pharmaceutical composition comprising multiple suppressor transfer rnas |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002508959A (ja) * | 1998-01-14 | 2002-03-26 | ヒューマン ジーン セラピー リサーチ インスティテュート | ヒトのサプレッサーｔＲＮＡオリゴヌクレオチド、及びそれを用いる方法 |
| WO2017049409A1 (en) * | 2015-09-25 | 2017-03-30 | The Centre For Drug Research And Development | Compositions for promoting readthrough of premature termination codons, and methods of using the same |
| CN107177592B (zh) * | 2016-03-10 | 2021-03-30 | 北京大学 | 抑制性tRNA通读提前终止密码子疾病中的截短蛋白 |
| PL3458074T3 (pl) * | 2016-05-16 | 2024-11-12 | Board Of Regents Of The University Of Texas System | KOMPOZYCJA DO DOSTARCZANIA tRNA W POSTACI NANOCZĄSTEK I SPOSOBY ICH STOSOWANIA |
| CN110612353A (zh) * | 2017-03-03 | 2019-12-24 | 加利福尼亚大学董事会 | 经由抑制性tRNAs和脱氨酶对突变进行RNA靶向 |
| KR102930465B1 (ko) * | 2017-11-02 | 2026-02-25 | 더 위스타 인스티튜트 오브 아나토미 앤드 바이올로지 | ACE-tRNA를 이용한 유전 재할당을 통한 정지 코돈의 구조 방법 |
-
2019
- 2019-09-26 EP EP19868108.2A patent/EP3856253A4/en not_active Withdrawn
- 2019-09-26 JP JP2021517046A patent/JP2022501055A/ja active Pending
- 2019-09-26 AU AU2019350869A patent/AU2019350869A1/en not_active Abandoned
- 2019-09-26 WO PCT/US2019/053260 patent/WO2020069194A1/en not_active Ceased
- 2019-09-26 CA CA3114108A patent/CA3114108A1/en active Pending
-
2023
- 2023-04-03 US US18/130,278 patent/US20240050594A1/en not_active Abandoned
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