JP2022500428A5 - - Google Patents
Info
- Publication number
- JP2022500428A5 JP2022500428A5 JP2021514039A JP2021514039A JP2022500428A5 JP 2022500428 A5 JP2022500428 A5 JP 2022500428A5 JP 2021514039 A JP2021514039 A JP 2021514039A JP 2021514039 A JP2021514039 A JP 2021514039A JP 2022500428 A5 JP2022500428 A5 JP 2022500428A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- fluoro
- isopropyl
- imidazo
- dihydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024017316A JP7706585B2 (ja) | 2018-09-14 | 2024-02-07 | 毛細血管拡張性運動失調症変異（ＡＴＭ）キナーゼの選択的調節物質としての１－イソプロピル－３－メチル－８－（ピリジン－３－イル）－１，３－ジヒドロ－２Ｈ－イミダゾ［４，５－ｃ］シンノリン－２－オンおよびその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2018105675 | 2018-09-14 | ||
| CNPCT/CN2018/105675 | 2018-09-14 | ||
| PCT/CN2019/105951 WO2020052688A1 (en) | 2018-09-14 | 2019-09-16 | 1-ISOPROPYL-3-METHYL-8- (PYRIDIN-3-YL) -1, 3-DIHYDRO-2H-IMIDAZO [4, 5-c] CINNOLIN-2-ONE AS SELECTIVE MODULATORS OF ATAXIA TELANGIECTASIA MUTATED (ATM) KINASE AND USES THEREOF |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024017316A Division JP7706585B2 (ja) | 2018-09-14 | 2024-02-07 | 毛細血管拡張性運動失調症変異（ＡＴＭ）キナーゼの選択的調節物質としての１－イソプロピル－３－メチル－８－（ピリジン－３－イル）－１，３－ジヒドロ－２Ｈ－イミダゾ［４，５－ｃ］シンノリン－２－オンおよびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022500428A JP2022500428A (ja) | 2022-01-04 |
| JP2022500428A5 true JP2022500428A5 (enExample) | 2022-09-30 |
| JP7436465B2 JP7436465B2 (ja) | 2024-02-21 |
Family
ID=69777300
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021514039A Active JP7436465B2 (ja) | 2018-09-14 | 2019-09-16 | 毛細血管拡張性運動失調症変異（ＡＴＭ）キナーゼの選択的調節物質としての１－イソプロピル－３－メチル－８－（ピリジン－３－イル）－１，３－ジヒドロ－２Ｈ－イミダゾ［４，５－ｃ］シンノリン－２－オンおよびその使用 |
| JP2024017316A Active JP7706585B2 (ja) | 2018-09-14 | 2024-02-07 | 毛細血管拡張性運動失調症変異（ＡＴＭ）キナーゼの選択的調節物質としての１－イソプロピル－３－メチル－８－（ピリジン－３－イル）－１，３－ジヒドロ－２Ｈ－イミダゾ［４，５－ｃ］シンノリン－２－オンおよびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024017316A Active JP7706585B2 (ja) | 2018-09-14 | 2024-02-07 | 毛細血管拡張性運動失調症変異（ＡＴＭ）キナーゼの選択的調節物質としての１－イソプロピル－３－メチル－８－（ピリジン－３－イル）－１，３－ジヒドロ－２Ｈ－イミダゾ［４，５－ｃ］シンノリン－２－オンおよびその使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US12226414B2 (enExample) |
| EP (2) | EP3849984B1 (enExample) |
| JP (2) | JP7436465B2 (enExample) |
| KR (1) | KR102813324B1 (enExample) |
| CN (2) | CN115636833B (enExample) |
| AU (1) | AU2019339006B2 (enExample) |
| CA (1) | CA3111994A1 (enExample) |
| ES (1) | ES3001444T3 (enExample) |
| WO (1) | WO2020052688A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115636833B (zh) * | 2018-09-14 | 2024-11-29 | 苏州赞荣医药科技有限公司 | 作为ATM激酶选择性调节剂的取代的咪唑并[4,5-c]噌啉-2-酮化合物及其用途 |
| AU2021433713A1 (en) | 2021-03-17 | 2023-09-28 | Suzhou Zanrong Pharma Limited | Selective modulators of ataxia telangiectasia mutated (atm) kinase and uses thereof |
| CN115304598B (zh) * | 2021-08-25 | 2024-05-31 | 石药集团中奇制药技术（石家庄）有限公司 | 一种杂环类化合物及其制备方法和用途 |
| GB202114704D0 (en) * | 2021-10-14 | 2021-12-01 | Univ Birmingham | ATM inhibition |
| MX2024009184A (es) * | 2022-01-26 | 2024-07-30 | Chia Tai Tianqing Pharmaceutical Group Co Ltd | Compuesto que contiene grupo hidrazino. |
| WO2025183591A1 (ru) * | 2024-02-29 | 2025-09-04 | Федеральное государственное унитарное предприятие "Всероссийский научно-исследовательский институт автоматики им. Н.Л. Духова" (ФГУП "ВНИИА") | Производные 2н-[1,4]оксазино- и 2h-[1, 4]тиазино[3,2-c]хинолин-3(4h)-онов в качестве ингибиторов атм и dna-pk киназ |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9624482D0 (en) | 1995-12-18 | 1997-01-15 | Zeneca Phaema S A | Chemical compounds |
| DE69720965T2 (de) | 1996-02-13 | 2004-02-05 | Astrazeneca Ab | Chinazolinderivate und deren verwendung als vegf hemmer |
| NZ331191A (en) | 1996-03-05 | 2000-03-27 | Zeneca Ltd | 4-anilinoquinazoline derivatives and pharmaceutical compositions thereof |
| GB9718972D0 (en) | 1996-09-25 | 1997-11-12 | Zeneca Ltd | Chemical compounds |
| NO2714752T3 (enExample) | 2014-05-08 | 2018-04-21 | ||
| GB201516504D0 (en) | 2015-09-17 | 2015-11-04 | Astrazeneca Ab | Imadazo(4,5-c)quinolin-2-one Compounds and their use in treating cancer |
| GB201519406D0 (en) | 2015-11-03 | 2015-12-16 | Astrazeneca Ab | Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer |
| GB201519568D0 (en) * | 2015-11-05 | 2015-12-23 | Astrazeneca Ab | Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer |
| CN108884084A (zh) | 2016-03-21 | 2018-11-23 | 阿斯利康(瑞典)有限公司 | 噌啉-4-胺化合物及其在治疗癌症中的用途 |
| GB201608227D0 (en) | 2016-05-11 | 2016-06-22 | Astrazeneca Ab | Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer |
| WO2019057757A1 (en) * | 2017-09-20 | 2019-03-28 | Astrazeneca Ab | 1,3-DIHYDROIMIDAZO [4,5-C] CINNOLIN-2-ONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF CANCER |
| CN115636833B (zh) * | 2018-09-14 | 2024-11-29 | 苏州赞荣医药科技有限公司 | 作为ATM激酶选择性调节剂的取代的咪唑并[4,5-c]噌啉-2-酮化合物及其用途 |
-
2019
- 2019-09-16 CN CN202211142049.1A patent/CN115636833B/zh active Active
- 2019-09-16 KR KR1020217006022A patent/KR102813324B1/ko active Active
- 2019-09-16 AU AU2019339006A patent/AU2019339006B2/en active Active
- 2019-09-16 EP EP19860219.5A patent/EP3849984B1/en active Active
- 2019-09-16 CA CA3111994A patent/CA3111994A1/en active Pending
- 2019-09-16 JP JP2021514039A patent/JP7436465B2/ja active Active
- 2019-09-16 ES ES19860219T patent/ES3001444T3/es active Active
- 2019-09-16 EP EP24212131.7A patent/EP4516318A3/en active Pending
- 2019-09-16 CN CN201980060250.5A patent/CN112752758B/zh active Active
- 2019-09-16 US US17/274,781 patent/US12226414B2/en active Active
- 2019-09-16 WO PCT/CN2019/105951 patent/WO2020052688A1/en not_active Ceased
-
2024
- 2024-02-07 JP JP2024017316A patent/JP7706585B2/ja active Active
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