JP2022171730A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2022171730A5 JP2022171730A5 JP2022139802A JP2022139802A JP2022171730A5 JP 2022171730 A5 JP2022171730 A5 JP 2022171730A5 JP 2022139802 A JP2022139802 A JP 2022139802A JP 2022139802 A JP2022139802 A JP 2022139802A JP 2022171730 A5 JP2022171730 A5 JP 2022171730A5
- Authority
- JP
- Japan
- Prior art keywords
- ligand
- reagent
- homodimer
- domain
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562160341P | 2015-05-12 | 2015-05-12 | |
| US62/160,341 | 2015-05-12 | ||
| JP2017558949A JP7240812B2 (ja) | 2015-05-12 | 2016-05-11 | 多量体タンパク質の純度の決定 |
| JP2021092988A JP7137663B2 (ja) | 2015-05-12 | 2021-06-02 | 多量体タンパク質の純度の決定 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021092988A Division JP7137663B2 (ja) | 2015-05-12 | 2021-06-02 | 多量体タンパク質の純度の決定 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022171730A JP2022171730A (ja) | 2022-11-11 |
| JP2022171730A5 true JP2022171730A5 (https=) | 2023-02-16 |
Family
ID=56072452
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017558949A Active JP7240812B2 (ja) | 2015-05-12 | 2016-05-11 | 多量体タンパク質の純度の決定 |
| JP2021092988A Active JP7137663B2 (ja) | 2015-05-12 | 2021-06-02 | 多量体タンパク質の純度の決定 |
| JP2022139802A Pending JP2022171730A (ja) | 2015-05-12 | 2022-09-02 | 多量体タンパク質の純度の決定 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017558949A Active JP7240812B2 (ja) | 2015-05-12 | 2016-05-11 | 多量体タンパク質の純度の決定 |
| JP2021092988A Active JP7137663B2 (ja) | 2015-05-12 | 2021-06-02 | 多量体タンパク質の純度の決定 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US10520511B2 (https=) |
| EP (2) | EP3885368A1 (https=) |
| JP (3) | JP7240812B2 (https=) |
| AR (1) | AR104610A1 (https=) |
| AU (2) | AU2016261854B2 (https=) |
| CA (1) | CA2984010A1 (https=) |
| ES (1) | ES2881359T3 (https=) |
| MA (2) | MA56416A (https=) |
| PL (1) | PL3294775T3 (https=) |
| WO (1) | WO2016183222A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4434629A3 (en) | 2015-11-30 | 2024-12-25 | Intabio, Llc | Methods for sample characterization |
| CN109937034B (zh) | 2016-11-21 | 2022-09-16 | 济世-伊沃泰克生物制品有限公司 | 阿柏西普制剂及其用途 |
| DK3668985T3 (da) | 2017-08-17 | 2021-09-20 | Just Evotec Biologics Inc | Fremgangsmåde til rensning af glycosyleret protein fra værtscellegalectiner og andre urenheder |
| CA3081094A1 (en) | 2017-11-20 | 2019-05-23 | Alison J. GILLESPIE | Aflibercept formulations containing a lysine salt as tonicifying agent and uses thereof |
| WO2019148198A1 (en) | 2018-01-29 | 2019-08-01 | Intabio, Inc. | Devices, methods and kits for sample characterization |
| EP3811397B1 (en) | 2018-05-31 | 2024-09-18 | Intabio, Llc | Methods for interfacing microfluidic systems with mass spectrometry |
| PL3837282T3 (pl) * | 2018-09-10 | 2026-02-16 | Genentech, Inc. | Układy i sposoby elektroforezy kapilarnej powinowactwa |
| US11573226B2 (en) | 2018-09-10 | 2023-02-07 | Genentech, Inc. | Systems and methods for affinity capillary electrophoresis |
| US11782023B2 (en) * | 2018-12-19 | 2023-10-10 | Regeneron Pharmaceuticals, Inc. | Ce-western applications for antibody development |
| CA3126712A1 (en) * | 2019-01-31 | 2020-08-06 | Regeneron Pharmaceuticals, Inc. | Native microfluidic ce-ms analysis of antibody charge heterogeneity |
| US11285484B2 (en) | 2019-08-12 | 2022-03-29 | Intabio, Llc | Multichannel isoelectric focusing devices and high voltage power supplies |
| US12594557B2 (en) | 2019-08-12 | 2026-04-07 | Intabio, Llc | Isoelectric focusing devices and fixtures |
| EP4323761A1 (en) * | 2021-04-14 | 2024-02-21 | DH Technologies Development Pte. Ltd. | Native fluorescence detection for protein analysis in capillary electrophoresis |
| JP2024544607A (ja) * | 2021-11-25 | 2024-12-03 | エフ． ホフマン－ラ ロシュ アーゲー | 少量の抗体副産物の定量 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPP385598A0 (en) * | 1998-06-02 | 1998-06-25 | Life Therapeutics Limited | Purification of antibodies |
| US6472179B2 (en) * | 1998-09-25 | 2002-10-29 | Regeneron Pharmaceuticals, Inc. | Receptor based antagonists and methods of making and using |
| JP4723725B2 (ja) * | 1999-04-20 | 2011-07-13 | ターゲット ディスカバリー， インコーポレイテッド | 代謝経路を分析するための方法 |
| US6818112B2 (en) * | 1999-04-20 | 2004-11-16 | Target Discovery, Inc. | Protein separation via multidimensional electrophoresis |
| US7087411B2 (en) | 1999-06-08 | 2006-08-08 | Regeneron Pharmaceuticals, Inc. | Fusion protein capable of binding VEGF |
| AUPQ743300A0 (en) * | 2000-05-11 | 2000-06-01 | Life Therapeutics Limited | Separation of avian antibodies |
| SG106672A1 (en) | 2002-03-08 | 2004-10-29 | Asml Netherlands Bv | Mask for use in lithography, method of making a mask, lithographic apparatus, and device manufacturing method |
| US20090134028A1 (en) * | 2005-09-22 | 2009-05-28 | Chemicals Evaluation And Research Institute | Method of Estimating Effect of Test Chemical on Living Organisms |
| EP1803814A1 (en) * | 2005-12-27 | 2007-07-04 | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. | Method of improving the antibody selection capacity in phage-display library |
| US9670269B2 (en) * | 2006-03-31 | 2017-06-06 | Chugai Seiyaku Kabushiki Kaisha | Methods of modifying antibodies for purification of bispecific antibodies |
| WO2008151219A1 (en) | 2007-06-04 | 2008-12-11 | Regeneron Pharmaceuticals, Inc. | Enhanced expression and stability regions |
| CN101874042B9 (zh) * | 2007-09-26 | 2019-01-01 | 中外制药株式会社 | 利用cdr的氨基酸取代来改变抗体等电点的方法 |
| JP4977588B2 (ja) * | 2007-12-07 | 2012-07-18 | 富士フイルム株式会社 | イムノクロマトグラフ方法 |
| JP5816170B2 (ja) | 2009-06-26 | 2015-11-18 | リジェネロン・ファーマシューティカルズ・インコーポレイテッドＲｅｇｅｎｅｒｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | 天然の免疫グロブリン形式を有する容易に単離される二重特異性抗体 |
| CA2836873C (en) * | 2011-05-21 | 2019-10-22 | Macrogenics, Inc. | Deimmunized serum-binding domains and their use for extending serum half-life |
| GB2504139B (en) | 2012-07-20 | 2014-12-31 | Argen X Bv | Antibodies to highly conserved targets produced by the immunisation of Camelidae species |
| EP2604624A1 (en) * | 2011-12-13 | 2013-06-19 | University College Dublin National University Of Ireland, Dublin | Bowman-Birk protease Inhibitor (BBI) binding peptides, and uses thereof in the separation, detection or purification of BBI. |
| PT2825559T (pt) * | 2012-03-13 | 2019-06-07 | Novimmune Sa | Anticorpos biespecíficos prontamente isolados com formato de imunoglobulina nativo |
| RU2014153674A (ru) | 2012-06-05 | 2016-07-27 | Регенерон Фармасьютикалз, Инк. | Способ получения полностью человеческих биспецифических антител с применением общей легкой цепи |
| TW202423993A (zh) * | 2012-11-14 | 2024-06-16 | 美商再生元醫藥公司 | 重組細胞表面捕捉蛋白質 |
| CA2919174A1 (en) * | 2013-08-19 | 2015-02-26 | F. Hoffmann-La Roche Ag | Separation of bispecific antibodies and bispecific antibody production side products using hydroxyapatite chromatography |
| US11261262B2 (en) * | 2013-09-03 | 2022-03-01 | Novimmune Sa | Readily isolated bispecific binding molecules with native format having mutated constant regions |
-
2016
- 2016-05-11 AU AU2016261854A patent/AU2016261854B2/en active Active
- 2016-05-11 PL PL16724805T patent/PL3294775T3/pl unknown
- 2016-05-11 EP EP21171963.8A patent/EP3885368A1/en not_active Withdrawn
- 2016-05-11 JP JP2017558949A patent/JP7240812B2/ja active Active
- 2016-05-11 ES ES16724805T patent/ES2881359T3/es active Active
- 2016-05-11 EP EP16724805.3A patent/EP3294775B1/en active Active
- 2016-05-11 CA CA2984010A patent/CA2984010A1/en active Pending
- 2016-05-11 US US15/152,135 patent/US10520511B2/en active Active
- 2016-05-11 WO PCT/US2016/031899 patent/WO2016183222A1/en not_active Ceased
- 2016-05-11 MA MA056416A patent/MA56416A/fr unknown
- 2016-05-11 MA MA043987A patent/MA43987A/fr unknown
- 2016-05-12 AR ARP160101379A patent/AR104610A1/es unknown
-
2019
- 2019-11-18 US US16/686,770 patent/US12158473B2/en active Active
-
2021
- 2021-06-02 JP JP2021092988A patent/JP7137663B2/ja active Active
-
2022
- 2022-05-05 AU AU2022203033A patent/AU2022203033B2/en not_active Expired - Fee Related
- 2022-09-02 JP JP2022139802A patent/JP2022171730A/ja active Pending
-
2024
- 2024-04-16 US US18/637,343 patent/US20240280587A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2022171730A5 (https=) | ||
| US20240280587A1 (en) | Multimeric protein purity determination | |
| IL276903B1 (en) | Bispecific egfr/cd16 antigen-binding protein | |
| JP2021152544A5 (https=) | ||
| JP2021152544A6 (ja) | 多量体タンパク質の純度の決定 | |
| JP2020530272A5 (https=) | ||
| JP2021515798A5 (https=) | ||
| JP2016505634A5 (https=) | ||
| JP2015504420A5 (https=) | ||
| JP2019523651A5 (https=) | ||
| JP2022069446A5 (https=) | ||
| JP2020516603A5 (https=) | ||
| RU2014128510A (ru) | Способ определения свободного связывающего партнера мультиспецифичного связующего | |
| JP2024156725A (ja) | 多量体タンパク質の量および純度を決定するための方法およびクロマトグラフィーシステム | |
| Amaral et al. | Rado� evic K, Rao E. Engineered Technologies and Bioanalysis of multispecific antibody formats | |
| JPWO2019175368A5 (https=) | ||
| JP2018525408A (ja) | アフィニティークロマトグラフィーにおける宿主細胞タンパク質の低減方法 | |
| KR102767384B1 (ko) | 마이코플라즈마 뉴모니에의 면역 측정 방법 및 면역 측정 기구 | |
| KR102397684B1 (ko) | 항체의 항원 결합 부위에 결합하는 펩티드 및 이를 이용한 분석 방법 | |
| JP2020515288A5 (https=) | ||
| RU2015140955A (ru) | Специфическое определение крысиных антител в сыворотке мышей | |
| Blanc et al. | A new method to discriminate immunogen-specific heavy-chain homodimer from heterotetramer immunoglobulin G directly in immunized dromedary whole plasma proteins: Western ligand blotting | |
| Goldman et al. | SdAb heterodimer formation using leucine zippers | |
| Star et al. | Intact Mass Spectrometry Analysis of Immuno-Isolated Human Therapeutic Antibodies from Serum | |
| HK40059237A (en) | Multimeric protein purity determination |