JP2022091998A5 - - Google Patents

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Publication number
JP2022091998A5
JP2022091998A5 JP2022064398A JP2022064398A JP2022091998A5 JP 2022091998 A5 JP2022091998 A5 JP 2022091998A5 JP 2022064398 A JP2022064398 A JP 2022064398A JP 2022064398 A JP2022064398 A JP 2022064398A JP 2022091998 A5 JP2022091998 A5 JP 2022091998A5
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JP
Japan
Prior art keywords
depot
use according
hydrolytically degradable
travoprost
xerogel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022064398A
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English (en)
Japanese (ja)
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JP7486539B2 (ja
JP2022091998A (ja
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Priority claimed from PCT/US2017/053271 external-priority patent/WO2018058048A1/en
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Publication of JP2022091998A publication Critical patent/JP2022091998A/ja
Publication of JP2022091998A5 publication Critical patent/JP2022091998A5/ja
Application granted granted Critical
Publication of JP7486539B2 publication Critical patent/JP7486539B2/ja
Active legal-status Critical Current
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JP2022064398A 2016-09-23 2022-04-08 前房内薬物送達デポ Active JP7486539B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201662398985P 2016-09-23 2016-09-23
US62/398,985 2016-09-23
PCT/US2017/053271 WO2018058048A1 (en) 2016-09-23 2017-09-25 Intracameral drug delivery depots
JP2019515849A JP7430529B2 (ja) 2016-09-23 2017-09-25 前房内薬物送達デポ

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2019515849A Division JP7430529B2 (ja) 2016-09-23 2017-09-25 前房内薬物送達デポ

Publications (3)

Publication Number Publication Date
JP2022091998A JP2022091998A (ja) 2022-06-21
JP2022091998A5 true JP2022091998A5 (https=) 2022-11-22
JP7486539B2 JP7486539B2 (ja) 2024-05-17

Family

ID=60022215

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019515849A Active JP7430529B2 (ja) 2016-09-23 2017-09-25 前房内薬物送達デポ
JP2022064398A Active JP7486539B2 (ja) 2016-09-23 2022-04-08 前房内薬物送達デポ

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2019515849A Active JP7430529B2 (ja) 2016-09-23 2017-09-25 前房内薬物送達デポ

Country Status (10)

Country Link
US (3) US12171869B2 (https=)
EP (2) EP3515406B1 (https=)
JP (2) JP7430529B2 (https=)
KR (3) KR102814241B1 (https=)
CN (1) CN109982683A (https=)
AU (1) AU2017331444B2 (https=)
DK (1) DK3515406T3 (https=)
ES (1) ES2989941T3 (https=)
IL (1) IL265421B2 (https=)
WO (1) WO2018058048A1 (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11458041B2 (en) 2015-10-08 2022-10-04 Ocular Therapeutix, Inc. Punctal plug and bioadhesives
DK3515406T3 (da) * 2016-09-23 2024-10-14 Incept Llc Intrakamerale depoter til lægemiddeladministration
CA3133172A1 (en) * 2019-03-13 2020-09-17 Susmita Bose Enzyme-degradable hydrogel for delivery of a payload
WO2020219892A1 (en) * 2019-04-25 2020-10-29 Ocular Therapeutix, Inc. Hydrogel implants for lowering intraocular pressure
WO2020219890A1 (en) * 2019-04-25 2020-10-29 Ocular Therapeutix, Inc. Ocular hydrogel tyrosine kinase inhibitor implants
US20200337993A1 (en) * 2019-04-25 2020-10-29 Ocular Therapeutix, Inc. Intracanalicular hydrogel inserts for the delivery of anesthetics
CA3166738A1 (en) * 2020-02-06 2021-08-12 Charles D. Blizzard Travoprost compositions and methods for treating ocular diseases
EP3884929B1 (en) * 2020-03-25 2023-06-14 Ocular Therapeutix, Inc. Ocular implant containing a tyrosine kinase inhibitor
WO2021222117A1 (en) 2020-04-27 2021-11-04 Ocular Therapeutix, Inc. Methods of treating allergic conjunctivitis
CA3174217A1 (en) * 2020-07-16 2022-01-20 Ocular Therapeutix, Inc. Ocular insert containing a glucocorticoid
TWI910236B (zh) * 2020-09-24 2026-01-01 美商視爾普斯眼科公司 包含水凝膠及環孢菌素之持續釋放可生物降解淚小管內插入物
EP4216929A1 (en) * 2020-09-24 2023-08-02 Ocular Therapeutix, Inc. Sustained release biodegradable intracanalicular inserts comprising a hydrogel and an active agent
EP4346720A4 (en) * 2021-05-28 2025-01-01 Sight Sciences, Inc. INTRAOCULAR DEVICES, SYSTEMS AND METHODS
CN114748436B (zh) * 2022-05-30 2023-05-16 迪沙药业集团有限公司 一种硝苯地平组合物及其制备方法
US20260048008A1 (en) * 2022-08-12 2026-02-19 Ocular Therapeutix, Inc. Organogels for sustained drug delivery, methods of preparation and use thereof
CN115337453A (zh) * 2022-08-15 2022-11-15 珠海肤原生物科技有限公司 一种载有2-氧杂环庚烷酮的均聚物微球的医用无菌胶原蛋白产品的制备
WO2024191453A1 (en) * 2023-03-10 2024-09-19 Clearstream Technologies Limited Radiation spacer hydrogels, methods of forming, and methods of use
CN120897764A (zh) 2023-04-11 2025-11-04 视尔普斯眼科公司 包含阿西替尼多晶型物iv的眼部植入物
WO2025255203A1 (en) * 2024-06-06 2025-12-11 Ocular Therapeutix, Inc. Compositions and methods for treating ocular diseases

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3640741A (en) 1970-02-24 1972-02-08 Hollister Inc Composition containing gel
US3865108A (en) 1971-05-17 1975-02-11 Ortho Pharma Corp Expandable drug delivery device
US4002173A (en) 1974-07-23 1977-01-11 International Paper Company Diester crosslinked polyglucan hydrogels and reticulated sponges thereof
DE2437629C3 (de) 1974-08-05 1978-09-21 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von unlöslichen in Wasser nur wenig quellbaren Polymerisaten von N-Vinyllactamen
US4014335A (en) 1975-04-21 1977-03-29 Alza Corporation Ocular drug delivery device
US4207893A (en) 1977-08-29 1980-06-17 Alza Corporation Device using hydrophilic polymer for delivering drug to biological environment
US4741872A (en) 1986-05-16 1988-05-03 The University Of Kentucky Research Foundation Preparation of biodegradable microspheres useful as carriers for macromolecules
US5160745A (en) 1986-05-16 1992-11-03 The University Of Kentucky Research Foundation Biodegradable microspheres as a carrier for macromolecules
IL82834A (en) 1987-06-09 1990-11-05 Yissum Res Dev Co Biodegradable polymeric materials based on polyether glycols,processes for the preparation thereof and surgical artiicles made therefrom
US4938763B1 (en) 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
US5304595A (en) 1988-11-21 1994-04-19 Collagen Corporation Collagen-polymer conjugates
US5162430A (en) 1988-11-21 1992-11-10 Collagen Corporation Collagen-polymer conjugates
IL90193A (en) 1989-05-04 1993-02-21 Biomedical Polymers Int Polurethane-based polymeric materials and biomedical articles and pharmaceutical compositions utilizing the same
FR2657018A1 (fr) 1990-01-12 1991-07-19 Merck Sharp & Dohme Composition ophtalmique fluide a base de microparticules lipidiques contenant au moins un principe actif et son procede de preparation.
US5410016A (en) 1990-10-15 1995-04-25 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
US6177401B1 (en) 1992-11-13 2001-01-23 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften Use of organic compounds for the inhibition of Flk-1 mediated vasculogenesis and angiogenesis
US6371975B2 (en) 1998-11-06 2002-04-16 Neomend, Inc. Compositions, systems, and methods for creating in situ, chemically cross-linked, mechanical barriers
WO1999021512A1 (en) 1997-10-27 1999-05-06 The Regents Of The University Of California Methods and pharmaceutical compositions for the closure of retinal breaks
US6632457B1 (en) 1998-08-14 2003-10-14 Incept Llc Composite hydrogel drug delivery systems
US6958212B1 (en) 1999-02-01 2005-10-25 Eidgenossische Technische Hochschule Zurich Conjugate addition reactions for the controlled delivery of pharmaceutically active compounds
US7141581B2 (en) 1999-07-02 2006-11-28 Agouron Pharmaceuticals, Inc. Indazole compounds and pharmaceutical compositions for inhibiting protein kinases, and methods for their use
TWI262914B (en) 1999-07-02 2006-10-01 Agouron Pharma Compounds and pharmaceutical compositions for inhibiting protein kinases
US20050049578A1 (en) 2000-04-14 2005-03-03 Hosheng Tu Implantable ocular pump to reduce intraocular pressure
AU2002236495B2 (en) 2000-11-29 2006-05-11 Allergan, Inc. Intraocular implants for preventing transplant rejection in the eye
JP2004523624A (ja) 2001-02-26 2004-08-05 デューク ユニバーシティ 新規なデンドリティックポリマー、およびその生物医学的使用
US6913765B2 (en) 2001-03-21 2005-07-05 Scimed Life Systems, Inc. Controlling resorption of bioresorbable medical implant material
US20040131582A1 (en) 2002-02-26 2004-07-08 Grinstaff Mark W. Novel dendritic polymers and their biomedical uses
US20040024345A1 (en) 2002-04-19 2004-02-05 Morteza Gharib Glaucoma implant with valveless flow bias
US7351430B2 (en) 2002-11-06 2008-04-01 Uluru Inc. Shape-retentive hydrogel particle aggregates and their uses
US20040137059A1 (en) 2003-01-09 2004-07-15 Thierry Nivaggioli Biodegradable ocular implant
US7129210B2 (en) 2003-07-23 2006-10-31 Covalent Medical, Inc. Tissue adhesive sealant
US8673341B2 (en) 2004-04-30 2014-03-18 Allergan, Inc. Intraocular pressure reduction with intracameral bimatoprost implants
US20050244458A1 (en) 2004-04-30 2005-11-03 Allergan, Inc. Sustained release intraocular implants and methods for treating ocular neuropathies
WO2006031358A2 (en) 2004-08-13 2006-03-23 Hyperbranch Medical Technology, Inc. Dendritic polymers, crosslinked gels, and their uses as ophthalmic sealants and lenses
WO2006031388A2 (en) 2004-08-20 2006-03-23 Hyperbranch Medical Technology, Inc. Dentritic polymers, crosslinked gels, and their uses in orthopedic applications
US20080038316A1 (en) 2004-10-01 2008-02-14 Wong Vernon G Conveniently implantable sustained release drug compositions
WO2007001926A2 (en) 2005-06-24 2007-01-04 Hyperbranch Medical Technology, Inc. Low-swelling hydrogel sealants for wound repair
WO2007005249A2 (en) 2005-06-29 2007-01-11 Hyperbranch Medical Technology, Inc. Nanoparticles and dendritic-polymer-based hydrogels comprising them
US9173773B2 (en) * 2006-06-21 2015-11-03 Johnson & Johnson Vision Care, Inc. Punctal plugs for the delivery of active agents
US9125807B2 (en) 2007-07-09 2015-09-08 Incept Llc Adhesive hydrogels for ophthalmic drug delivery
US8409606B2 (en) 2009-02-12 2013-04-02 Incept, Llc Drug delivery through hydrogel plugs
US20100247606A1 (en) 2009-03-25 2010-09-30 Allergan, Inc. Intraocular sustained release drug delivery systems and methods for treating ocular conditions
WO2011010399A1 (ja) 2009-07-24 2011-01-27 千寿製薬株式会社 角膜内皮細胞増殖促進剤
US7856528B1 (en) 2009-08-11 2010-12-21 Texas Memory Systems, Inc. Method and apparatus for protecting data using variable size page stripes in a FLASH-based storage system
US8383161B2 (en) 2009-12-15 2013-02-26 Incept, Llc Radioopaque covalently crosslinked hydrogel particle implants
EP3085358B1 (en) 2010-01-22 2017-11-01 Allergan, Inc. Intracameral sustained release therapeutic agent implants
EP2538929A4 (en) 2010-02-25 2014-07-09 Univ Johns Hopkins DELAYED RELEASE OF THERAPIES IN A PART OF THE EYE
EP2555749B1 (en) 2010-04-06 2016-10-26 Allergan, Inc. Sustained-release reservoir implants for intracameral drug delivery
US8961501B2 (en) 2010-09-17 2015-02-24 Incept, Llc Method for applying flowable hydrogels to a cornea
US10226417B2 (en) * 2011-09-16 2019-03-12 Peter Jarrett Drug delivery systems and applications
AU2012347926B2 (en) 2011-12-05 2018-03-15 Incept, Llc Medical organogel processes and compositions
EP2950782B1 (en) 2013-01-31 2017-12-27 Icon Bioscience, Inc. Sustained release formulations for the treatment of intraocular pressure or glaucoma
CA2939952C (en) 2013-03-05 2022-03-22 Morgan V. Fedorchak Thermoresponsive hydrogel containing polymer microparticles for noninvasive ocular drug delivery
WO2014143754A2 (en) 2013-03-15 2014-09-18 Allergan, Inc. Prostamide-containing intraocular implant
ES2834964T3 (es) 2013-04-01 2021-06-21 Allergan Inc Sistema de administración de fármacos mediante microesferas para liberación intraocular sostenida
MX2016007345A (es) 2013-12-06 2016-12-09 Envisia Therapeutics Inc Implante intracameral para el tratamiento de una condicion ocular.
AU2015360469B2 (en) * 2014-12-10 2021-03-25 Incept, Llc Hydrogel drug delivery implants
KR20180086468A (ko) 2015-11-25 2018-07-31 인셉트, 엘엘씨 형상 변형 약물 전달 장치 및 방법
DK3515406T3 (da) 2016-09-23 2024-10-14 Incept Llc Intrakamerale depoter til lægemiddeladministration

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