JP2022068197A5 - - Google Patents

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Publication number
JP2022068197A5
JP2022068197A5 JP2022014178A JP2022014178A JP2022068197A5 JP 2022068197 A5 JP2022068197 A5 JP 2022068197A5 JP 2022014178 A JP2022014178 A JP 2022014178A JP 2022014178 A JP2022014178 A JP 2022014178A JP 2022068197 A5 JP2022068197 A5 JP 2022068197A5
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JP
Japan
Prior art keywords
examples
prepared
same procedure
procedure
same
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Pending
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JP2022014178A
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English (en)
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JP2022068197A (ja
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Priority claimed from JP2019572352A external-priority patent/JP7178375B2/ja
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Publication of JP2022068197A publication Critical patent/JP2022068197A/ja
Publication of JP2022068197A5 publication Critical patent/JP2022068197A5/ja
Pending legal-status Critical Current

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Description

実施例22~86:実施例22~86は、実施例1~21に記載されているものと同様
の手順によって調製した。
Figure 2022068197000001
Figure 2022068197000002
Figure 2022068197000003
Figure 2022068197000004
Figure 2022068197000005
Figure 2022068197000006
Figure 2022068197000007
Figure 2022068197000008
Figure 2022068197000009
Figure 2022068197000010
Figure 2022068197000011
Figure 2022068197000012
Figure 2022068197000013
Figure 2022068197000014
Figure 2022068197000015
Figure 2022068197000016
Figure 2022068197000017
Figure 2022068197000018
Figure 2022068197000019
Figure 2022068197000020
Figure 2022068197000021
Figure 2022068197000022
Figure 2022068197000023
JP2022014178A 2017-03-13 2022-02-01 デュアルmagl及びfaahインヒビター Pending JP2022068197A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201762470830P 2017-03-13 2017-03-13
US62/470,830 2017-03-13
JP2019572352A JP7178375B2 (ja) 2017-03-13 2018-03-12 デュアルmagl及びfaahインヒビター
PCT/US2018/022049 WO2018169880A1 (en) 2017-03-13 2018-03-12 Dual magl and faah inhibitors

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2019572352A Division JP7178375B2 (ja) 2017-03-13 2018-03-12 デュアルmagl及びfaahインヒビター

Publications (2)

Publication Number Publication Date
JP2022068197A JP2022068197A (ja) 2022-05-09
JP2022068197A5 true JP2022068197A5 (ja) 2022-06-30

Family

ID=63445929

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2019572352A Active JP7178375B2 (ja) 2017-03-13 2018-03-12 デュアルmagl及びfaahインヒビター
JP2022014178A Pending JP2022068197A (ja) 2017-03-13 2022-02-01 デュアルmagl及びfaahインヒビター
JP2022105683A Active JP7440572B2 (ja) 2017-03-13 2022-06-30 デュアルmagl及びfaahインヒビター
JP2024020785A Pending JP2024056887A (ja) 2017-03-13 2024-02-15 デュアルmagl及びfaahインヒビター

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2019572352A Active JP7178375B2 (ja) 2017-03-13 2018-03-12 デュアルmagl及びfaahインヒビター

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2022105683A Active JP7440572B2 (ja) 2017-03-13 2022-06-30 デュアルmagl及びfaahインヒビター
JP2024020785A Pending JP2024056887A (ja) 2017-03-13 2024-02-15 デュアルmagl及びfaahインヒビター

Country Status (21)

Country Link
US (3) US10350205B2 (ja)
EP (3) EP4335848A3 (ja)
JP (4) JP7178375B2 (ja)
KR (2) KR20230173732A (ja)
CN (5) CN117510468A (ja)
AR (2) AR111271A1 (ja)
AU (3) AU2018236161B9 (ja)
BR (1) BR112019018879A2 (ja)
CA (1) CA3056076A1 (ja)
CL (1) CL2019002583A1 (ja)
CO (1) CO2019009932A2 (ja)
EA (1) EA201991898A1 (ja)
EC (1) ECSP19066721A (ja)
IL (3) IL301334B2 (ja)
MX (1) MX2022006862A (ja)
NZ (1) NZ756915A (ja)
SA (1) SA519410101B1 (ja)
SG (1) SG11201908159QA (ja)
TW (2) TW202346280A (ja)
WO (1) WO2018169880A1 (ja)
ZA (1) ZA201905934B (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ627750A (en) 2012-01-06 2016-11-25 Abide Therapeutics Inc Carbamate compounds and of making and using same
JOP20190107A1 (ar) 2016-11-16 2019-05-09 Lundbeck La Jolla Research Center Inc مثبطات أحادي أسيل جليسرول ليباز (magl)
AU2018236161B9 (en) * 2017-03-13 2022-03-31 Lundbeck La Jolla Research Center, Inc. Dual MAGL and FAAH inhibitors
MX2021002923A (es) * 2018-09-13 2021-09-08 Celgene Corp (r)-5-carbamoilpiridin-3-il-2-metil-4-(3-(trifluorometoxi)bencil) piperazin-1-carboxilato cristalino, composiciones y sus metodos de uso.

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006527212A (ja) * 2003-06-12 2006-11-30 ノボ ノルディスク アクティーゼルスカブ ホルモン感受性リパーゼの阻害剤として使用するための、置換ピペラジンカルバメート
CA2525207A1 (en) * 2003-06-12 2004-12-23 Novo Nordisk A/S Substituted piperidine carbamates for use as inhibitors of hormone sensitive lipase
JP2006088075A (ja) 2004-09-27 2006-04-06 Kubota Corp 脱臭装置
ES2528674T3 (es) 2005-02-17 2015-02-11 Astellas Pharma Inc. Piperidina y carboxilatos de piperacina como inhibidores de FAAH
KR20080003350A (ko) * 2005-03-18 2008-01-07 인스티튜트 포 케미컬 게노믹스 α-헬릭스 유사물 및 섬유증 치료에 관한 방법
CA2743861A1 (en) 2008-11-14 2010-05-20 The Scripps Research Institute Methods and compositions related to targeting monoacylglycerol lipase
US8461159B2 (en) * 2008-11-25 2013-06-11 Jannsen Pharmaceutica BV Heteroaryl-substituted urea modulators of fatty acid amide hydrolase
FR2945531A1 (fr) * 2009-05-12 2010-11-19 Sanofi Aventis Derives de 7-aza-spiro°3,5!nonane-7-carboxylates, leur preparation et leur application en therapeutique
WO2010141817A1 (en) * 2009-06-05 2010-12-09 Janssen Pharmaceutica Nv Heteroaryl-substituted spirocyclic diamine urea modulators of fatty acid amide hydrolase
MX2012008801A (es) * 2010-01-28 2012-08-17 Merck Sharp & Dohme Composiciones farmaceuticas para el tratamiento de dolor y otras indicaciones.
JP2013147430A (ja) * 2010-04-28 2013-08-01 Astellas Pharma Inc 夜間頻尿の予防又は治療剤
TW201206440A (en) * 2010-04-28 2012-02-16 Astellas Pharma Inc Prophylactic or therapeutic agent for diseases associated with pains in urinary organs
BR112015011441A2 (pt) 2012-11-20 2017-07-11 Merial Inc composições e compostos antihelmínticos e métodos de usos dos mesmos
JP2016513112A (ja) 2013-02-18 2016-05-12 ザ スクリプス リサーチ インスティテュート 治療的潜在能力を有するバソプレッシン受容体のモジュレーター
CA2917050A1 (en) * 2013-07-03 2015-01-08 Todd K. Jones Pyrrolo-pyrrole carbamate and related organic compounds, pharmaceutical compositions, and medical uses thereof
EP3099332A4 (en) * 2014-01-29 2017-06-21 Madrigal Pharmaceuticals, Inc. Targeted therapeutics
WO2016014975A2 (en) * 2014-07-25 2016-01-28 Northeastern University Urea/carbamates faah magl or dual faah/magl inhibitors and uses thereof
WO2016149401A2 (en) * 2015-03-18 2016-09-22 Abide Therapeutics, Inc. Piperazine carbamates and methods of making and using same
EP3328849B9 (en) 2015-07-31 2021-01-06 Pfizer Inc. 1,1,1-trifluoro-3-hydroxypropan-2-yl carbamate derivatives and 1,1,1-trifluoro-4-hydroxybutan-2-yl carbamate derivatives as magl inhibitors
AU2018236161B9 (en) 2017-03-13 2022-03-31 Lundbeck La Jolla Research Center, Inc. Dual MAGL and FAAH inhibitors

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