JP2021535087A5 - - Google Patents
Info
- Publication number
- JP2021535087A5 JP2021535087A5 JP2021505981A JP2021505981A JP2021535087A5 JP 2021535087 A5 JP2021535087 A5 JP 2021535087A5 JP 2021505981 A JP2021505981 A JP 2021505981A JP 2021505981 A JP2021505981 A JP 2021505981A JP 2021535087 A5 JP2021535087 A5 JP 2021535087A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- group
- cycloalkyl
- fibrosis
- cancer
- Prior art date
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2018902829 | 2018-08-03 | ||
| AU2018902829A AU2018902829A0 (en) | 2018-08-03 | Haloallylamine sulfone derivative inhibitors of lysyl oxidases and uses thereof | |
| PCT/AU2019/050811 WO2020024017A1 (en) | 2018-08-03 | 2019-08-02 | Haloallylamine sulfone derivative inhibitors of lysyl oxidases and uses thereof |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021535087A JP2021535087A (ja) | 2021-12-16 |
| JPWO2020024017A5 JPWO2020024017A5 (https=) | 2022-08-04 |
| JP2021535087A5 true JP2021535087A5 (https=) | 2022-08-04 |
| JP7414803B2 JP7414803B2 (ja) | 2024-01-16 |
Family
ID=69230421
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021505981A Active JP7414803B2 (ja) | 2018-08-03 | 2019-08-02 | リシルオキシダーゼのハロアリルアミンスルホン誘導体阻害剤およびそれらの使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US12178791B2 (https=) |
| EP (1) | EP3829520B1 (https=) |
| JP (1) | JP7414803B2 (https=) |
| KR (1) | KR102780601B1 (https=) |
| CN (1) | CN112533897B (https=) |
| AR (1) | AR115906A1 (https=) |
| AU (1) | AU2019315330B2 (https=) |
| CA (1) | CA3105599A1 (https=) |
| ES (1) | ES3010655T3 (https=) |
| MX (1) | MX2021001347A (https=) |
| TW (1) | TW202019877A (https=) |
| WO (1) | WO2020024017A1 (https=) |
| ZA (1) | ZA202100148B (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2020317374A1 (en) * | 2019-07-25 | 2022-02-03 | Pharmaxis Ltd. | Difluorohaloallylamine sulfone derivative inhibitors of lysyl oxidases, methods of preparation, and uses thereof |
| US12578335B2 (en) * | 2020-02-05 | 2026-03-17 | Syntara Limited | Bioprobes for lysyl oxidases and uses thereof |
| EP4173639A4 (en) * | 2020-06-26 | 2024-03-13 | RaQualia Pharma Inc. | METHOD FOR SELECTING A CANCER PATIENT FOR WHICH COMBINATION THERAPY OF A RETINOID AND A CANCER TREATMENT AGENT WILL BE EFFECTIVE, AND COMBINATION DRUG OF A RETINOID AND A CANCER TREATMENT AGENT |
| US12233056B2 (en) * | 2022-04-06 | 2025-02-25 | Syntara Limited | Lysyl oxidase inhibitors for treating myeloid malignancies |
| JP2025528475A (ja) * | 2022-08-29 | 2025-08-28 | シンタラ・リミテッド | リシルオキシダーゼの新規選択的阻害剤 |
| MA71743A (fr) * | 2022-11-07 | 2025-05-30 | Eisai R&D Management Co., Ltd. | Procédé de production d'un composé macrolide |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE28819E (en) | 1972-12-08 | 1976-05-18 | Syntex (U.S.A.) Inc. | Dialkylated glycol compositions and medicament preparations containing same |
| US4358603A (en) | 1981-04-16 | 1982-11-09 | Syntex (U.S.A.) Inc. | Acetal stabilized prostaglandin compositions |
| US4454158A (en) | 1981-06-01 | 1984-06-12 | Merrell Toraude Et Compagnie | Allyl amine MAO inhibitors |
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US4699928A (en) | 1984-07-13 | 1987-10-13 | Merrell Dow Pharmaceuticals Inc. | Fluoroallylamine derivatives |
| US4965288A (en) | 1988-02-25 | 1990-10-23 | Merrell Dow Pharmaceuticals Inc. | Inhibitors of lysyl oxidase |
| US5182297A (en) | 1988-02-25 | 1993-01-26 | Merrell Dow Pharmaceuticals Inc. | Inhibitors of lysyl oxidase |
| US4943593A (en) | 1988-02-25 | 1990-07-24 | Merrell Dow Pharmaceuticals Inc. | Inhibitors of lysyl oxidase |
| US5252608A (en) | 1988-02-25 | 1993-10-12 | Merrell Dow Pharmaceuticals Inc. | Inhibitors of lysyl oxidase |
| US5021456A (en) | 1988-02-25 | 1991-06-04 | Merrell Dow Pharmaceuticals Inc. | Inhibitors of lysyl oxidase |
| US5059714A (en) | 1988-02-25 | 1991-10-22 | Merrell Dow Pharmaceuticals Inc. | Inhibitors of lysyl oxidase |
| DE10216144A1 (de) | 2002-04-12 | 2003-11-06 | Bayer Ag | Substituierte 2-Phenyl-3(2H)-Pyridazinone |
| DE102004056226A1 (de) | 2004-11-22 | 2006-05-24 | Burchardt, Elmar Reinhold, Dr.Dr. | Neuartige Inhibitoren der Lysyloxidase |
| US20080293969A1 (en) | 2005-11-22 | 2008-11-27 | Ge Healthcare Limited | 18F-Labeled Daa Analogues and Method of Labeling These Analogues as Positron Emission Tomography (Pet) Tracers For Imaging Peripheral Benzodiazepine Receptors |
| WO2007120528A2 (en) | 2006-03-31 | 2007-10-25 | La Jolla Pharmaceutical Company | Inhibitors of semicarbazide-sensitive amine oxidase (ssao) and vap-1 mediated adhesion useful for treatment and prevention of diseases |
| US20080293936A1 (en) | 2007-05-23 | 2008-11-27 | Elmar Reinhold Burchardt | Novel inhibitors of lysyl oxidase |
| CA2693310C (en) | 2007-08-02 | 2018-11-27 | Arresto Biosciences, Inc. | Lox and loxl2 inhibitors, antibodies and uses thereof |
| JP2011504485A (ja) | 2007-11-21 | 2011-02-10 | ファーマクシス リミテッド | Ｓｓａｏ／ｖａｐ−１のハロアリルアミン阻害剤およびその用途 |
| WO2011022670A1 (en) | 2009-08-21 | 2011-02-24 | Arresto Biosciences, Inc | In vivo screening assays |
| EP3438087A1 (en) * | 2012-05-02 | 2019-02-06 | Boehringer Ingelheim International GmbH | Substituted 3-haloallylamine inhibitors of ssao and uses thereof |
| WO2016144702A1 (en) | 2015-03-06 | 2016-09-15 | Pharmakea, Inc. | Lysyl oxidase-like 2 inhibitors and uses thereof |
| JP6697809B2 (ja) | 2015-03-06 | 2020-05-27 | ファーマケア，インク． | フッ素化リシルオキシダーゼ様２阻害剤とその使用 |
| EP3317258A4 (en) | 2015-07-01 | 2019-06-26 | Pharmakea, Inc. | LYSYL OXIDASE LIKE 2 INHIBITORS AND USES THEREOF |
| US20180215727A1 (en) | 2015-07-23 | 2018-08-02 | Pharmakea, Inc. | Lysyl oxidase-like 2 inhibitors and uses thereof |
| JP6849197B2 (ja) | 2016-02-12 | 2021-03-24 | ファーマクシス リミテッド | リジルオキシダーゼのインドールおよびアザインドールハロアリルアミン誘導体阻害剤およびその使用 |
| GB201602934D0 (en) | 2016-02-19 | 2016-04-06 | Cancer Res Inst Royal | Compounds |
| WO2018048930A1 (en) | 2016-09-07 | 2018-03-15 | Pharmakea, Inc. | Lysyl oxidase-like 2 inhibitors and uses thereof |
| US20200069648A1 (en) * | 2017-03-02 | 2020-03-05 | Pharmaxis Ltd. | Haloallylamine pyrazole derivative inhibitors of lysyl oxidases and uses thereof |
| GB201716871D0 (en) | 2017-10-13 | 2017-11-29 | Inst Of Cancer Research: Royal Cancer Hospital | Compounds |
-
2019
- 2019-08-02 CN CN201980051571.9A patent/CN112533897B/zh active Active
- 2019-08-02 JP JP2021505981A patent/JP7414803B2/ja active Active
- 2019-08-02 ES ES19844663T patent/ES3010655T3/es active Active
- 2019-08-02 CA CA3105599A patent/CA3105599A1/en active Pending
- 2019-08-02 WO PCT/AU2019/050811 patent/WO2020024017A1/en not_active Ceased
- 2019-08-02 TW TW108127609A patent/TW202019877A/zh unknown
- 2019-08-02 AU AU2019315330A patent/AU2019315330B2/en active Active
- 2019-08-02 AR ARP190102210A patent/AR115906A1/es unknown
- 2019-08-02 EP EP19844663.5A patent/EP3829520B1/en active Active
- 2019-08-02 US US17/265,402 patent/US12178791B2/en active Active
- 2019-08-02 KR KR1020217003279A patent/KR102780601B1/ko active Active
- 2019-08-02 MX MX2021001347A patent/MX2021001347A/es unknown
-
2021
- 2021-01-08 ZA ZA2021/00148A patent/ZA202100148B/en unknown
-
2024
- 2024-11-21 US US18/955,223 patent/US20250082593A1/en active Pending
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