JP2021533113A - 新規なマイオカイン及びその使用 - Google Patents

新規なマイオカイン及びその使用 Download PDF

Info

Publication number
JP2021533113A
JP2021533113A JP2021505195A JP2021505195A JP2021533113A JP 2021533113 A JP2021533113 A JP 2021533113A JP 2021505195 A JP2021505195 A JP 2021505195A JP 2021505195 A JP2021505195 A JP 2021505195A JP 2021533113 A JP2021533113 A JP 2021533113A
Authority
JP
Japan
Prior art keywords
polypeptide
amino acid
acid sequence
muscle
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021505195A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021533113A5 (enExample
Inventor
ホフリング,ホルガー
ケラー,ハンスヨルグ
ルミール,ソフィー
サマーマター,サージ
Original Assignee
ノバルティス アーゲー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ノバルティス アーゲー filed Critical ノバルティス アーゲー
Publication of JP2021533113A publication Critical patent/JP2021533113A/ja
Publication of JP2021533113A5 publication Critical patent/JP2021533113A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/06—Anabolic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4725—Proteoglycans, e.g. aggreccan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP2021505195A 2018-08-02 2019-07-31 新規なマイオカイン及びその使用 Pending JP2021533113A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18187131.0 2018-08-02
EP18187131 2018-08-02
PCT/IB2019/056537 WO2020026167A1 (en) 2018-08-02 2019-07-31 New myokines and uses thereof

Publications (2)

Publication Number Publication Date
JP2021533113A true JP2021533113A (ja) 2021-12-02
JP2021533113A5 JP2021533113A5 (enExample) 2022-08-08

Family

ID=63144838

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021505195A Pending JP2021533113A (ja) 2018-08-02 2019-07-31 新規なマイオカイン及びその使用

Country Status (10)

Country Link
US (1) US20220144908A1 (enExample)
EP (1) EP3829620B1 (enExample)
JP (1) JP2021533113A (enExample)
KR (1) KR20210041580A (enExample)
CN (1) CN112512553A (enExample)
AU (1) AU2019313506A1 (enExample)
CA (1) CA3106518A1 (enExample)
IL (1) IL280369A (enExample)
TW (1) TW202019457A (enExample)
WO (1) WO2020026167A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113424794B (zh) * 2021-04-16 2022-07-26 安徽农业大学 一种优质抗病型地方鸡新品系选育方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003004532A2 (en) * 2001-07-05 2003-01-16 Geneprot, Inc. Q9ul33/q9nzz4 and q9h5p3 splice variants
JP2004313167A (ja) * 2003-02-24 2004-11-11 Joji Inasawa 薬剤耐性マーカーおよびその利用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998042738A1 (en) 1997-03-21 1998-10-01 Human Genome Sciences, Inc. 87 human secreted proteins
CA2305689A1 (en) 1997-10-02 1999-04-15 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
CA2311201A1 (en) 1999-08-05 2001-02-05 Genset S.A. Ests and encoded human proteins

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003004532A2 (en) * 2001-07-05 2003-01-16 Geneprot, Inc. Q9ul33/q9nzz4 and q9h5p3 splice variants
JP2004313167A (ja) * 2003-02-24 2004-11-11 Joji Inasawa 薬剤耐性マーカーおよびその利用

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
"Evaluating the Impact of Novel Bone Marrow Cell-secreted Factors, C19orf10 and C1orf54, on Immunomod", A THESIS SUBMITTED IN CONFORMITY WITH THE REQUIREMENTS FOR THE DEGREE OF MASTER OF SCIENCE INSTITUTE, JPN7023002581, 2017, pages 1 - 149, ISSN: 0005269861 *
J CELL MOL MED., vol. 22, JPN6023027714, 12 July 2018 (2018-07-12), pages 4985 - 4996, ISSN: 0005269860 *

Also Published As

Publication number Publication date
TW202019457A (zh) 2020-06-01
CN112512553A (zh) 2021-03-16
WO2020026167A1 (en) 2020-02-06
US20220144908A1 (en) 2022-05-12
EP3829620B1 (en) 2024-05-29
EP3829620A1 (en) 2021-06-09
AU2019313506A1 (en) 2021-01-14
IL280369A (en) 2021-03-01
KR20210041580A (ko) 2021-04-15
CA3106518A1 (en) 2020-02-06

Similar Documents

Publication Publication Date Title
JP7829511B2 (ja) Larファミリーホスファターゼの活性を阻害する組成物及び方法
JP6786544B2 (ja) 成長ホルモン断片の使用
CN108472336B (zh) C型利尿钠肽变体在治疗骨骼发育不良中的用途
EA035158B1 (ru) Пептиды и композиции для лечения повреждений суставов
KR20190129058A (ko) 성인 및 청소년에서 저포스파타제증 (hpp)을 치료하는 방법
EP3829620B1 (en) New myokines and uses thereof
JP7624240B2 (ja) 脊髄性筋萎縮症を治療する方法及び薬剤
Morishita et al. Subacute intranasal oxytocin improves neurological recovery after ischemic stroke
CN116744958A (zh) 骨关节炎疼痛的治疗
US10729746B2 (en) Recombinant placenta growth factor for treating Duchenne muscular dystrophy
CA3058816A1 (en) Proteins derived from clpb and uses thereof
JP2007515375A (ja) 多系統萎縮症におけるヒト成長ホルモンの使用
JP2019525931A (ja) ヒト成長ホルモンアナログによる成人成長ホルモン欠乏症の処置
Talan In Gene Therapy Trial for DMD, No Evidence of Sustained Gene Expression But a T-Cell Response is Reported
EA042134B1 (ru) МИМЕТИЧЕСКИЕ ПЕПТИДЫ apoC-II

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20220729

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20220729

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20230628

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20230704

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20231002

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20231204

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20231228

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20240227

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20240508

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20241022