JP2021530989A5 - - Google Patents

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Publication number
JP2021530989A5
JP2021530989A5 JP2021500868A JP2021500868A JP2021530989A5 JP 2021530989 A5 JP2021530989 A5 JP 2021530989A5 JP 2021500868 A JP2021500868 A JP 2021500868A JP 2021500868 A JP2021500868 A JP 2021500868A JP 2021530989 A5 JP2021530989 A5 JP 2021530989A5
Authority
JP
Japan
Prior art keywords
domain
igg1
domain monomer
monomer
polypeptide
Prior art date
Application number
JP2021500868A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021530989A (ja
JPWO2020014419A5 (https=
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/041306 external-priority patent/WO2020014419A2/en
Publication of JP2021530989A publication Critical patent/JP2021530989A/ja
Publication of JP2021530989A5 publication Critical patent/JP2021530989A5/ja
Publication of JPWO2020014419A5 publication Critical patent/JPWO2020014419A5/ja
Withdrawn legal-status Critical Current

Links

JP2021500868A 2018-07-11 2019-07-11 PD−L1を標的とした改変されたFc抗原結合ドメイン構築体に関する組成物および方法 Withdrawn JP2021530989A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862696711P 2018-07-11 2018-07-11
US62/696,711 2018-07-11
PCT/US2019/041306 WO2020014419A2 (en) 2018-07-11 2019-07-11 Compositions and methods related to engineered fc-antigen binding domain constructs targeted to pd-l1

Publications (3)

Publication Number Publication Date
JP2021530989A JP2021530989A (ja) 2021-11-18
JP2021530989A5 true JP2021530989A5 (https=) 2022-07-20
JPWO2020014419A5 JPWO2020014419A5 (https=) 2022-07-20

Family

ID=69141681

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021500868A Withdrawn JP2021530989A (ja) 2018-07-11 2019-07-11 PD−L1を標的とした改変されたFc抗原結合ドメイン構築体に関する組成物および方法

Country Status (11)

Country Link
US (1) US20210147549A1 (https=)
EP (1) EP3820998A4 (https=)
JP (1) JP2021530989A (https=)
KR (1) KR20210044782A (https=)
CN (1) CN112996910A (https=)
AU (1) AU2019299935A1 (https=)
BR (1) BR112021000383A2 (https=)
CA (1) CA3106108A1 (https=)
IL (1) IL280038A (https=)
MX (1) MX2021000281A (https=)
WO (1) WO2020014419A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024219897A1 (ko) * 2023-04-21 2024-10-24 상트네어바이오사이언스 주식회사 두 개의 fab 도메인 및 두 개의 fc 도메인을 포함하는 항원 결합 단백질 및 이의 용도
WO2024219894A1 (ko) * 2023-04-21 2024-10-24 상트네어바이오사이언스 주식회사 두 개의 fc 도메인을 포함하는 항원 결합 단백질 및 이의 용도
CN117736329B (zh) * 2023-12-25 2024-11-12 华润生物医药有限公司 抗pd-1抗体及其用途

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20201595T1 (hr) * 2011-11-28 2020-12-11 Merck Patent Gmbh Anti-pd-l1 protutijela i njihova uporaba
AU2013229488B2 (en) * 2012-03-08 2017-12-07 Janssen Vaccines & Prevention B.V. Human binding molecules capable of binding to and neutralizing influenza B viruses and uses thereof
US20150203591A1 (en) * 2012-08-02 2015-07-23 Regeneron Pharmaceuticals, Inc. Mutivalent antigen-binding proteins
JP2017518965A (ja) * 2014-05-02 2017-07-13 モメンタ ファーマシューティカルズ インコーポレイテッ エンジニアリングされたFc構築物に関連する組成物および方法
JP6744313B2 (ja) * 2015-01-02 2020-08-26 ダイアックス コーポレーション 血漿カリクレインおよび第xii因子に対する二重特異性抗体
US9512229B2 (en) * 2015-03-03 2016-12-06 Kymab Limited Synergistic combinations of OX40L antibodies for the treatment of GVHD
PH12017501857B1 (en) * 2015-06-16 2024-01-17 Merck Patent Gmbh Pd-l1 antagonist combination treatments
CA3000386A1 (en) * 2015-09-30 2017-04-06 Merck Patent Gmbh Combination of a pd-1 axis binding antagonist and an alk inhibitor for treating alk-negative cancer
CN106939047B (zh) * 2016-01-04 2021-08-31 江苏怀瑜药业有限公司 一种pd-l1抗体及其制备方法
WO2017151971A2 (en) * 2016-03-02 2017-09-08 Momenta Pharmaceuticals, Inc. METHODS RELATED TO ENGINEERED Fc CONSTRUCTS
CN108779180B (zh) * 2016-03-23 2020-10-16 迈博斯生物医药(苏州)有限公司 新型抗-pd-l1抗体
BR112018074056A2 (pt) * 2016-05-23 2019-03-06 Momenta Pharmaceuticals, Inc. composições e métodos relacionados a construtos de fc manipulados
WO2018009466A1 (en) * 2016-07-05 2018-01-11 Aduro Biotech, Inc. Locked nucleic acid cyclic dinucleotide compounds and uses thereof
WO2018115262A1 (en) * 2016-12-23 2018-06-28 Innate Pharma Heterodimeric antigen binding proteins

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