JP2020514301A5 - - Google Patents
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- Publication number
- JP2020514301A5 JP2020514301A5 JP2019537110A JP2019537110A JP2020514301A5 JP 2020514301 A5 JP2020514301 A5 JP 2020514301A5 JP 2019537110 A JP2019537110 A JP 2019537110A JP 2019537110 A JP2019537110 A JP 2019537110A JP 2020514301 A5 JP2020514301 A5 JP 2020514301A5
- Authority
- JP
- Japan
- Prior art keywords
- domain
- domain monomer
- monomer
- polypeptide
- linker
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762443523P | 2017-01-06 | 2017-01-06 | |
| US62/443,523 | 2017-01-06 | ||
| PCT/US2018/012689 WO2018129397A1 (en) | 2017-01-06 | 2018-01-05 | Compositions and methods related to engineered fc-antigen binding domain constructs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020514301A JP2020514301A (ja) | 2020-05-21 |
| JP2020514301A5 true JP2020514301A5 (https=) | 2021-02-18 |
Family
ID=62791385
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019537110A Pending JP2020514301A (ja) | 2017-01-06 | 2018-01-05 | 改変されたＦｃ抗原結合ドメイン構築体に関する組成物および方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20200040084A1 (https=) |
| EP (1) | EP3565595A4 (https=) |
| JP (1) | JP2020514301A (https=) |
| AU (1) | AU2018205272A1 (https=) |
| CA (1) | CA3049426A1 (https=) |
| RU (1) | RU2019124709A (https=) |
| WO (1) | WO2018129397A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112912103B (zh) * | 2018-05-21 | 2025-08-29 | 广州邦定生物技术有限公司 | 多价蛋白质复合物 |
| JP2021531757A (ja) * | 2018-07-11 | 2021-11-25 | モメンタ ファーマシューティカルズ インコーポレイテッド | 改変されたＦｃ−抗原結合ドメイン構築体に関する組成物および方法 |
| WO2020014542A2 (en) * | 2018-07-11 | 2020-01-16 | Momenta Pharmaceuticals, Inc. | Compositions and methods related to engineered fc-antigen binding domain constructs |
| US20220267460A1 (en) * | 2018-07-11 | 2022-08-25 | Momenta Pharmaceuticals, Inc. | COMPOSITIONS AND METHODS RELATED TO ENGINEERED Fc-ANTIGEN BINDING DOMAIN CONSTRUCTS |
| CN113382749A (zh) * | 2018-07-11 | 2021-09-10 | 动量制药公司 | 与工程化Fc-抗原结合结构域构建体有关的组合物和方法 |
| MX2021010039A (es) * | 2019-02-26 | 2021-09-21 | Pieris Pharmaceuticals Gmbh | Novedosas proteinas de fusion especificas para cd137 y gpc3. |
| CN111909268B (zh) * | 2019-05-07 | 2022-04-19 | 北京天成新脉生物技术有限公司 | 低免疫原性低ADCC/CDC功能抗TNF-α人源化单克隆抗体TCX060及其应用 |
| CA3155187A1 (en) * | 2019-09-18 | 2021-03-25 | Momenta Pharmaceuticals, Inc. | Compositions and methods related to engineered fc-antigen binding domain constructs targeted to cd38 |
| WO2021189006A1 (en) * | 2020-03-20 | 2021-09-23 | Keros Therapeutics, Inc. | Methods of using activin receptor type iia variants |
| KR20230060546A (ko) * | 2021-10-22 | 2023-05-04 | 상트네어바이오사이언스 주식회사 | 두개의 Fc 도메인을 포함하는 항원 결합 단백질 및 이의 용도 |
| WO2024219897A1 (ko) | 2023-04-21 | 2024-10-24 | 상트네어바이오사이언스 주식회사 | 두 개의 fab 도메인 및 두 개의 fc 도메인을 포함하는 항원 결합 단백질 및 이의 용도 |
| WO2024219894A1 (ko) | 2023-04-21 | 2024-10-24 | 상트네어바이오사이언스 주식회사 | 두 개의 fc 도메인을 포함하는 항원 결합 단백질 및 이의 용도 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090304715A1 (en) * | 2006-03-03 | 2009-12-10 | Tokyo University Of Science | Modified antibodies with enhanced biological activities |
| US20080311034A1 (en) * | 2007-04-30 | 2008-12-18 | Anderson Glenn M | Anti-Tissue Factor Antibodies and Compositions with Enhanced Effector Function |
| WO2012116926A1 (en) * | 2011-02-28 | 2012-09-07 | F. Hoffmann-La Roche Ag | Antigen binding proteins |
| KR101632620B1 (ko) * | 2011-07-27 | 2016-06-23 | 글락소 그룹 리미티드 | Ｆｃ 도메인에 융합된 항ｖｅｇｆ 단일 가변 도메인 |
| TW201444872A (zh) * | 2013-03-06 | 2014-12-01 | Merrimack Pharmaceuticals Inc | 抗Ｃ－ＭＥＴ串聯Ｆｃ雙特異性抗體 |
| US10858417B2 (en) * | 2013-03-15 | 2020-12-08 | Xencor, Inc. | Heterodimeric proteins |
| JP2017518965A (ja) * | 2014-05-02 | 2017-07-13 | モメンタ ファーマシューティカルズ インコーポレイテッ | エンジニアリングされたＦｃ構築物に関連する組成物および方法 |
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2018
- 2018-01-05 RU RU2019124709A patent/RU2019124709A/ru unknown
- 2018-01-05 JP JP2019537110A patent/JP2020514301A/ja active Pending
- 2018-01-05 AU AU2018205272A patent/AU2018205272A1/en not_active Abandoned
- 2018-01-05 US US16/474,572 patent/US20200040084A1/en not_active Abandoned
- 2018-01-05 EP EP18735797.5A patent/EP3565595A4/en not_active Withdrawn
- 2018-01-05 CA CA3049426A patent/CA3049426A1/en not_active Abandoned
- 2018-01-05 WO PCT/US2018/012689 patent/WO2018129397A1/en not_active Ceased