JP2021528435A5 - - Google Patents
Info
- Publication number
- JP2021528435A5 JP2021528435A5 JP2020571498A JP2020571498A JP2021528435A5 JP 2021528435 A5 JP2021528435 A5 JP 2021528435A5 JP 2020571498 A JP2020571498 A JP 2020571498A JP 2020571498 A JP2020571498 A JP 2020571498A JP 2021528435 A5 JP2021528435 A5 JP 2021528435A5
- Authority
- JP
- Japan
- Prior art keywords
- antibodies
- mixture
- antibody
- different
- substitution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024086125A JP2024109884A (ja) | 2018-06-22 | 2024-05-28 | ２つ以上の異なる抗体の制御された混合物を産生するための方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18179365 | 2018-06-22 | ||
| EP18179365.4 | 2018-06-22 | ||
| PCT/EP2019/066594 WO2019243626A1 (en) | 2018-06-22 | 2019-06-24 | Method for producing a controlled mixture of two or more different antibodies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024086125A Division JP2024109884A (ja) | 2018-06-22 | 2024-05-28 | ２つ以上の異なる抗体の制御された混合物を産生するための方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021528435A JP2021528435A (ja) | 2021-10-21 |
| JP2021528435A5 true JP2021528435A5 (https=) | 2022-07-01 |
Family
ID=62841830
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020571498A Pending JP2021528435A (ja) | 2018-06-22 | 2019-06-24 | ２つ以上の異なる抗体の制御された混合物を産生するための方法 |
| JP2024086125A Pending JP2024109884A (ja) | 2018-06-22 | 2024-05-28 | ２つ以上の異なる抗体の制御された混合物を産生するための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024086125A Pending JP2024109884A (ja) | 2018-06-22 | 2024-05-28 | ２つ以上の異なる抗体の制御された混合物を産生するための方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US12247065B2 (https=) |
| EP (1) | EP3810649A1 (https=) |
| JP (2) | JP2021528435A (https=) |
| CN (1) | CN112513074A (https=) |
| CA (1) | CA3104390A1 (https=) |
| IL (1) | IL279528A (https=) |
| MA (1) | MA52945A (https=) |
| SG (1) | SG11202012713RA (https=) |
| WO (1) | WO2019243626A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI874341B (zh) | 2018-12-18 | 2025-03-01 | 美商健生生物科技公司 | 產生異二聚體抗體之方法 |
| JP7778705B2 (ja) | 2020-02-21 | 2025-12-02 | ジェンマブ ビー．ブイ． | 糖蛋白質の定量のための方法 |
| EP4372001A4 (en) * | 2021-07-14 | 2025-02-12 | Jiangsu Hengrui Pharmaceuticals Co., Ltd. | ANTIGEN-BINDING MOLECULE SPECIFICALLY BINDING TO HGFR AND EGFR, AND PHARMACEUTICAL USE THEREOF |
| EP4624493A1 (en) * | 2022-11-24 | 2025-10-01 | Jiangsu Hengrui Pharmaceuticals Co., Ltd. | Pharmaceutical composition comprising bispecific antibody specifically binding to hgfr and egfr |
| TW202509077A (zh) * | 2023-06-30 | 2025-03-01 | 丹麥商珍美寶股份有限公司 | 與纖維母細胞活化蛋白α及死亡受體４結合之抗體 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1400536A1 (en) | 1991-06-14 | 2004-03-24 | Genentech Inc. | Method for making humanized antibodies |
| GB9203459D0 (en) | 1992-02-19 | 1992-04-08 | Scotgen Ltd | Antibodies with germ-line variable regions |
| DE59309332D1 (de) * | 1993-12-27 | 1999-03-04 | Rotkreuzstiftung Zentratrallab | Verfahren zur Herstellung eines Konzentrates von Anti-D-Immunoglobulin G und pharmazeutische Zusammensetzung, die dieses enthält |
| JP4593783B2 (ja) | 1998-07-21 | 2010-12-08 | ゲンマブ・アクティーゼルスカブ | 抗ｃ型肝炎ウイルス抗体およびその使用 |
| CA2450285C (en) | 2001-06-13 | 2016-08-02 | Genmab A/S | Human monoclonal antibodies to epidermal growth factor receptor (egfr) |
| DK2314629T4 (da) | 2002-07-18 | 2023-02-06 | Merus Nv | Rekombinant produktion af blandinger af antistoffer |
| BRPI0315295C1 (pt) | 2002-10-17 | 2021-05-25 | Genmab As | anticorpo monoclonal humano isolado, célula hospedeira procariótica, composição farmacêutica, molécula biespecífica, usos de um anticorpo, métodos in vitro de detectar a presença de antígeno de cd20 ou uma célula que expressa cd20 em uma amostra, kit, e, vetor de expressão |
| SI1583830T1 (sl) | 2003-01-07 | 2006-12-31 | Symphogen As | Postopek za pripravo rekombinantnih poliklonskih proteinov |
| US8288109B2 (en) * | 2004-07-20 | 2012-10-16 | Symphogen A/S | Procedure for structural characterization of a recombinant polyclonal protein or a polyclonal cell line |
| EA014182B1 (ru) * | 2004-07-20 | 2010-10-29 | Симфоген А/С | КОМПОЗИЦИЯ ПОЛИКЛОНАЛЬНЫХ АНТИ-RhD АНТИТЕЛ, СПОСОБ ЕЁ ПОЛУЧЕНИЯ И ПРИМЕНЕНИЕ КОМПОЗИЦИИ |
| EP2009101B1 (en) | 2006-03-31 | 2017-10-25 | Chugai Seiyaku Kabushiki Kaisha | Antibody modification method for purifying bispecific antibody |
| CL2007003622A1 (es) | 2006-12-13 | 2009-08-07 | Medarex Inc | Anticuerpo monoclonal humano anti-cd19; composicion que lo comprende; y metodo de inhibicion del crecimiento de celulas tumorales. |
| MX2009012526A (es) * | 2007-05-25 | 2009-12-09 | Symphogen As | Metodo para fabricar una proteina policlonal recombinante. |
| NZ588651A (en) | 2008-04-23 | 2012-04-27 | Symphogen As | Methods for manufacturing a polyclonal protein |
| WO2010089387A1 (en) | 2009-02-09 | 2010-08-12 | Morphosys Ag | Production of oligoclonal mixtures of immunoglobulins in single cells |
| MY192182A (en) | 2009-06-26 | 2022-08-04 | Regeneron Pharma | Readily isolated bispecific antibodies with native immunoglobulin format |
| SG10201501803YA (en) | 2010-03-12 | 2015-05-28 | Immunogen Inc | Cd37-binding molecules and immunoconjugates thereof |
| HRP20241208T1 (hr) | 2010-04-20 | 2024-11-22 | Genmab A/S | Heterodimerni proteini koji sadrže fc fragment protutijela i postupci za njihovu proizvodnju |
| CA2800769C (en) | 2010-05-27 | 2021-11-02 | Genmab A/S | Monoclonal antibodies against her2 epitope |
| WO2012068317A2 (en) | 2010-11-16 | 2012-05-24 | Excelimmune, Inc. | Methods for producing recombinant proteins |
| CN103796678B (zh) | 2011-04-20 | 2018-02-27 | 健玛保 | 针对her2的双特异性抗体 |
| UA117901C2 (uk) | 2011-07-06 | 2018-10-25 | Ґенмаб Б.В. | Спосіб посилення ефекторної функції вихідного поліпептиду, його варіанти та їх застосування |
| PT2768857T (pt) | 2011-10-19 | 2020-01-27 | Novimmune Sa | Métodos para purificar anticorpos |
| EP3517548A1 (en) * | 2012-03-13 | 2019-07-31 | NovImmune S.A. | Readily isolated bispecific antibodies with native immunoglobulin format |
| AU2013322710A1 (en) * | 2012-09-25 | 2015-04-16 | Glenmark Pharmaceuticals S.A. | Purification of hetero-dimeric immunoglobulins |
| KR20200024345A (ko) | 2013-01-10 | 2020-03-06 | 젠맵 비. 브이 | 인간 IgG1 Fc 영역 변이체 및 그의 용도 |
| HK1222871A1 (zh) | 2013-05-13 | 2017-07-14 | Medimmune, Llc | 具有最小单体分离的重组多克隆抗体多聚体的分离 |
| SMT202000265T1 (it) | 2014-07-11 | 2020-07-08 | Genmab As | Anticorpi che legano axl |
| EP3233907B1 (en) * | 2014-12-19 | 2021-03-03 | Genmab A/S | Rodent bispecific heterodimeric proteins |
| US12595316B2 (en) | 2015-07-09 | 2026-04-07 | Genmab A/S | Bispecific and multispecific antibodies and method for isolation of such |
| US11020686B2 (en) * | 2016-08-16 | 2021-06-01 | Regeneron Pharmaceuticals, Inc. | Methods for quantitating individual antibodies from a mixture |
-
2019
- 2019-06-24 EP EP19734332.0A patent/EP3810649A1/en active Pending
- 2019-06-24 JP JP2020571498A patent/JP2021528435A/ja active Pending
- 2019-06-24 CA CA3104390A patent/CA3104390A1/en active Pending
- 2019-06-24 SG SG11202012713RA patent/SG11202012713RA/en unknown
- 2019-06-24 CN CN201980050655.0A patent/CN112513074A/zh active Pending
- 2019-06-24 WO PCT/EP2019/066594 patent/WO2019243626A1/en not_active Ceased
- 2019-06-24 US US17/253,286 patent/US12247065B2/en active Active
- 2019-06-24 MA MA052945A patent/MA52945A/fr unknown
-
2020
- 2020-12-17 IL IL279528A patent/IL279528A/en unknown
-
2024
- 2024-05-28 JP JP2024086125A patent/JP2024109884A/ja active Pending
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