JP2021527099A5 - - Google Patents
Info
- Publication number
- JP2021527099A5 JP2021527099A5 JP2020569188A JP2020569188A JP2021527099A5 JP 2021527099 A5 JP2021527099 A5 JP 2021527099A5 JP 2020569188 A JP2020569188 A JP 2020569188A JP 2020569188 A JP2020569188 A JP 2020569188A JP 2021527099 A5 JP2021527099 A5 JP 2021527099A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- isoxazole
- pyridazin
- methylpyridine
- pyridazine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18177522.2 | 2018-06-13 | ||
| EP18177522 | 2018-06-13 | ||
| EP18177825.9 | 2018-06-14 | ||
| EP18177825 | 2018-06-14 | ||
| PCT/EP2019/065129 WO2019238633A1 (en) | 2018-06-13 | 2019-06-11 | New isoxazolyl ether derivatives as gaba a alpha5 pam |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021527099A JP2021527099A (ja) | 2021-10-11 |
| JP2021527099A5 true JP2021527099A5 (enExample) | 2022-06-13 |
| JP7478676B2 JP7478676B2 (ja) | 2024-05-07 |
Family
ID=66776367
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020569188A Active JP7478676B2 (ja) | 2018-06-13 | 2019-06-11 | Ｇａｂａ ａ ａｌｐｈａ５ ｐａｍとしての新規イソオキサゾリルエーテル誘導体 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US11840528B2 (enExample) |
| EP (1) | EP3807269A1 (enExample) |
| JP (1) | JP7478676B2 (enExample) |
| KR (1) | KR20210021019A (enExample) |
| CN (1) | CN112424196A (enExample) |
| AU (1) | AU2019286312B2 (enExample) |
| BR (1) | BR112020025355A2 (enExample) |
| CA (1) | CA3102101A1 (enExample) |
| CL (1) | CL2020003214A1 (enExample) |
| CR (1) | CR20200610A (enExample) |
| IL (1) | IL279266B2 (enExample) |
| MA (1) | MA52868A (enExample) |
| MX (1) | MX2020013518A (enExample) |
| PE (1) | PE20210555A1 (enExample) |
| PH (1) | PH12020500674A1 (enExample) |
| SG (1) | SG11202012200QA (enExample) |
| TW (1) | TWI816812B (enExample) |
| WO (1) | WO2019238633A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI901650B (zh) | 2020-03-26 | 2025-10-21 | 匈牙利商羅特格登公司 | 啶及吡啶并〔３，４－ｃ〕嗒衍生物 |
| CN115461337A (zh) * | 2020-05-13 | 2022-12-09 | 豪夫迈·罗氏有限公司 | 作为GABA A α5 PAM的新型三唑基衍生物 |
| HU231691B1 (hu) | 2021-09-29 | 2025-10-28 | Richter Gedeon Nyrt | GABAA ALFA5 receptor modulátor hatású biciklusos aminszármazékok |
| JP2026009006A (ja) * | 2024-07-01 | 2026-01-19 | 日本たばこ産業株式会社 | ピリダジノン化合物及びその医薬用途 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2682301A1 (en) * | 2007-04-18 | 2008-10-30 | Astrazeneca Ab | Xanthine compounds having a positive allosteric gabab receptor modulator effect |
| UA100132C2 (en) * | 2007-12-04 | 2012-11-26 | Ф. Хоффманн-Ля Рош Аг | Isoxazolo-pyridine derivatives |
| US7943619B2 (en) | 2007-12-04 | 2011-05-17 | Hoffmann-La Roche Inc. | Isoxazolo-pyridazine derivatives |
| CA2724842A1 (en) | 2008-05-19 | 2009-11-26 | Sunovion Pharmaceuticals Inc. | Imidazo[1,2-a]pyridine compounds |
| AU2010244552A1 (en) * | 2009-05-05 | 2011-09-29 | F. Hoffmann-La Roche Ag | Isoxazole-pyrazole derivatives |
| US8604062B2 (en) | 2011-10-20 | 2013-12-10 | Hoffman-La Roche Inc. | Process for the preparation of isoxazolyl-methoxy nicotinic acids |
| US8785435B2 (en) | 2011-10-20 | 2014-07-22 | Hoffmann-La Roche Inc. | Solid forms |
| ES2910110T3 (es) | 2016-12-08 | 2022-05-11 | Hoffmann La Roche | Nuevos derivados de isoxazolil-éter como PAM de alfa 5 GABA A |
-
2019
- 2019-06-11 IL IL279266A patent/IL279266B2/en unknown
- 2019-06-11 CN CN201980046146.0A patent/CN112424196A/zh active Pending
- 2019-06-11 KR KR1020217000958A patent/KR20210021019A/ko not_active Ceased
- 2019-06-11 AU AU2019286312A patent/AU2019286312B2/en not_active Ceased
- 2019-06-11 PE PE2020001963A patent/PE20210555A1/es unknown
- 2019-06-11 MA MA052868A patent/MA52868A/fr unknown
- 2019-06-11 EP EP19729015.8A patent/EP3807269A1/en active Pending
- 2019-06-11 BR BR112020025355-3A patent/BR112020025355A2/pt not_active IP Right Cessation
- 2019-06-11 MX MX2020013518A patent/MX2020013518A/es unknown
- 2019-06-11 CR CR20200610A patent/CR20200610A/es unknown
- 2019-06-11 WO PCT/EP2019/065129 patent/WO2019238633A1/en not_active Ceased
- 2019-06-11 SG SG11202012200QA patent/SG11202012200QA/en unknown
- 2019-06-11 CA CA3102101A patent/CA3102101A1/en active Pending
- 2019-06-11 JP JP2020569188A patent/JP7478676B2/ja active Active
- 2019-06-12 TW TW108120285A patent/TWI816812B/zh not_active IP Right Cessation
-
2020
- 2020-12-10 CL CL2020003214A patent/CL2020003214A1/es unknown
- 2020-12-10 PH PH12020500674A patent/PH12020500674A1/en unknown
- 2020-12-11 US US17/119,977 patent/US11840528B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2473549C2 (ru) | Пиримидиновые соединения, композиции и способы применения | |
| JP2021527099A5 (enExample) | ||
| JP2021519291A5 (enExample) | ||
| JP2015522002A5 (enExample) | ||
| JP2025533831A (ja) | Ｋｒａｓ ｇ１２ｃ変異タンパク質のテザー型複素環式阻害剤及びその使用 | |
| JP2014506929A5 (enExample) | ||
| RU2016135637A (ru) | 6-гетероарилокси- и 6-арилоксихинолин-2-карбоксамиды и их применение | |
| RU2018142987A (ru) | Положительные аллостерические модуляторы мускаринового ацетилхолинового рецептора m4 | |
| JP2018500376A5 (enExample) | ||
| RU2019115115A (ru) | Производные пиперидина в качестве ингибиторов убиквитин-специфической протеазы 7 | |
| JP2019535664A5 (enExample) | ||
| WO2017004500A9 (en) | Bicyclic lactams and methods of use thereof | |
| JP2014534976A5 (enExample) | ||
| JP2021504380A5 (enExample) | ||
| JP2021521165A5 (enExample) | ||
| JP2017505327A5 (enExample) | ||
| IL306126A (en) | Heterocyclic compounds | |
| JP2016525092A5 (enExample) | ||
| JP2015537010A5 (enExample) | ||
| US11840528B2 (en) | Isoxazolyl ether derivatives as GABAA α5 PAM | |
| KR20190088485A (ko) | Gaba a 알파5 pam으로서 신규한 이소옥사졸릴 에터 유도체 | |
| HRP20250272T1 (hr) | Derivati benzimidazola i njihova uporaba | |
| JP2024511841A5 (enExample) | ||
| JP2024518811A (ja) | カルボニル置換ジアザスピロ化合物及びその使用 | |
| JP2022508523A5 (enExample) |