JP2021526525A5 - - Google Patents
Info
- Publication number
- JP2021526525A5 JP2021526525A5 JP2020566845A JP2020566845A JP2021526525A5 JP 2021526525 A5 JP2021526525 A5 JP 2021526525A5 JP 2020566845 A JP2020566845 A JP 2020566845A JP 2020566845 A JP2020566845 A JP 2020566845A JP 2021526525 A5 JP2021526525 A5 JP 2021526525A5
- Authority
- JP
- Japan
- Prior art keywords
- dose
- adc
- here
- patient
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024095931A JP2024154433A (ja) | 2018-06-07 | 2024-06-13 | 抗体薬物コンジュゲート（ａｄｃｓ）を用いた治療方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862682154P | 2018-06-07 | 2018-06-07 | |
| US62/682,154 | 2018-06-07 | ||
| US201962841702P | 2019-05-01 | 2019-05-01 | |
| US62/841,702 | 2019-05-01 | ||
| PCT/IB2019/054748 WO2019234694A2 (en) | 2018-06-07 | 2019-06-07 | Therapeutic methods using antibody drug conjugates (adcs) |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024095931A Division JP2024154433A (ja) | 2018-06-07 | 2024-06-13 | 抗体薬物コンジュゲート（ａｄｃｓ）を用いた治療方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021526525A JP2021526525A (ja) | 2021-10-07 |
| JP2021526525A5 true JP2021526525A5 (https=) | 2022-06-14 |
Family
ID=68769968
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020566845A Pending JP2021526525A (ja) | 2018-06-07 | 2019-06-07 | 抗体薬物コンジュゲート（ａｄｃｓ）を用いた治療方法 |
| JP2024095931A Pending JP2024154433A (ja) | 2018-06-07 | 2024-06-13 | 抗体薬物コンジュゲート（ａｄｃｓ）を用いた治療方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024095931A Pending JP2024154433A (ja) | 2018-06-07 | 2024-06-13 | 抗体薬物コンジュゲート（ａｄｃｓ）を用いた治療方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20210283267A1 (https=) |
| EP (1) | EP3801635A4 (https=) |
| JP (2) | JP2021526525A (https=) |
| CN (1) | CN112566671A (https=) |
| AU (1) | AU2019283654A1 (https=) |
| CA (1) | CA3101943A1 (https=) |
| WO (1) | WO2019234694A2 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019084057A2 (en) | 2017-10-24 | 2019-05-02 | Magenta Therapeutics, Inc. | COMPOSITIONS AND METHODS FOR DEPLOYING CD117 + CELLS |
| AU2019265019B2 (en) | 2018-05-11 | 2025-11-06 | Beam Therapeutics Inc. | Methods of substituting pathogenic amino acids using programmable base editor systems |
| WO2020219748A2 (en) * | 2019-04-24 | 2020-10-29 | Magenta Therapeutics, Inc. | Anti-cd117 antibodies and uses thereof |
| EP3958909A4 (en) * | 2019-04-24 | 2024-01-10 | Magenta Therapeutics, Inc. | ANTI-CD117 ANTIBODY DRUG CONJUGATES AND USES THEREOF |
| EP3959242A4 (en) * | 2019-04-24 | 2023-09-13 | Magenta Therapeutics, Inc. | ANTRACYCLINE ANTIBODY-DRUG CONJUGATES AND THEIR USES |
| JP2022530443A (ja) * | 2019-04-24 | 2022-06-29 | マジェンタ セラピューティクス インコーポレイテッド | 抗ｃｄ１１７抗体薬物複合体およびその使用 |
| GB202004263D0 (en) * | 2020-03-24 | 2020-05-06 | Autolus Ltd | Antibody conjugate |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1928912A4 (en) * | 2005-09-07 | 2010-02-24 | Medimmune Inc | EPH ANTI-RECEPTOR ANTIBODIES CONJUGATED TO TOXINS |
| PT2099823E (pt) * | 2006-12-01 | 2014-12-22 | Seattle Genetics Inc | Agentes de ligação ao alvo variantes e suas utilizações |
| AR086044A1 (es) * | 2011-05-12 | 2013-11-13 | Imclone Llc | Anticuerpos que se unen especificamente a un dominio extracelular de c-kit y usos de los mismos |
| EP4257145B1 (en) * | 2014-08-26 | 2025-06-25 | The Board of Trustees of the Leland Stanford Junior University | Engraftment of stem cells with a combination of an agent that targets stem cells and modulation of immunoregulatory signaling |
| JP6668345B2 (ja) * | 2014-11-21 | 2020-03-18 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | 修飾された重鎖定常領域を含む抗体 |
| HK1256681A1 (zh) * | 2015-04-06 | 2019-10-04 | President And Fellows Of Harvard College | 用於非清髓性预处理的组合物和方法 |
| CA2984892A1 (en) * | 2015-05-04 | 2016-11-10 | Cytomx Therapeutics, Inc. | Anti-itga3 antibodies, activatable anti-itga3 antibodies, and methods of use thereof |
| EP3222292A1 (en) * | 2016-03-03 | 2017-09-27 | Heidelberg Pharma GmbH | Amanitin conjugates |
| WO2017191579A1 (en) * | 2016-05-05 | 2017-11-09 | Novartis Ag | Amatoxin derivatives and conjugates thereof as inhibitors of rna polymerase |
| IL263744B2 (en) * | 2016-06-17 | 2023-11-01 | Magenta Therapeutics Inc | Compositions and methods for the depletion of cd117 plus cells |
| KR20240093751A (ko) * | 2016-12-21 | 2024-06-24 | 노파르티스 아게 | 조혈줄기세포를 제거하기 위한 항체 약물 접합체 |
| EP3624839A4 (en) * | 2017-05-17 | 2021-06-16 | Immunogen, Inc. | DOSING PLANS FOR ANTI-CD33 IMMUNE CONJUGATES |
-
2019
- 2019-06-07 JP JP2020566845A patent/JP2021526525A/ja active Pending
- 2019-06-07 AU AU2019283654A patent/AU2019283654A1/en active Pending
- 2019-06-07 EP EP19815485.8A patent/EP3801635A4/en active Pending
- 2019-06-07 CN CN201980052505.3A patent/CN112566671A/zh active Pending
- 2019-06-07 WO PCT/IB2019/054748 patent/WO2019234694A2/en not_active Ceased
- 2019-06-07 CA CA3101943A patent/CA3101943A1/en active Pending
-
2020
- 2020-12-04 US US17/111,816 patent/US20210283267A1/en not_active Abandoned
-
2024
- 2024-06-13 JP JP2024095931A patent/JP2024154433A/ja active Pending
-
2025
- 2025-02-28 US US19/067,310 patent/US20260014202A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2021526525A5 (https=) | ||
| AU2021225125B9 (en) | Antibody drug conjugate loaded with binary toxins and its application | |
| JP5314590B2 (ja) | カンプトテシン結合部分 | |
| KR102459468B1 (ko) | 결합 링커, 그러한 결합 링커를 함유하는 세포 결합 분자-약물 결합체, 링커를 갖는 그러한 결합체의 제조 및 사용 | |
| TWI362934B (en) | Phosphonate analogs of hiv inhibitor compounds | |
| JP2020506176A5 (https=) | ||
| ES2931923T3 (es) | Inmunoconjugados con una enlace intracelularmente escindible | |
| JP2022512778A5 (https=) | ||
| US20230295346A1 (en) | Prodruggable antibodies, prodrugs thereof, and methods of use and making | |
| HUE027549T2 (hu) | Hatóanyagot tartalmazó konjugátumok és alkalmazásuk rák, autoimmun betegség vagy fertõzéses betegség kezelésére | |
| SA517382248B1 (ar) | مركبات 4،6-ديامينو-بيريدو بيريميدين تعدل مستقبل بروتين ناقل غشائي [3،2-d] | |
| JP2010516675A (ja) | 治療薬剤のポリマー担体および疾病部位の抗体に基づく標的化のための認識部分 | |
| WO2016028573A1 (en) | Antigen binding proteins that bind cxcr5 | |
| JP2018509394A5 (https=) | ||
| CN117157098A (zh) | 一种药物组合及其用途 | |
| EA022408B1 (ru) | Производные санглиферина и способы их получения | |
| TW202432559A (zh) | 一類連接子藥物及其抗體-藥物偶聯物的製備方法和應用 | |
| CN1817866A (zh) | 一组连有核苷碱基的格尔德霉素衍生物 | |
| WO2000067792A1 (fr) | Anticorps monoclonal dirige contre les cellules de carcinome renal humain | |
| US11717540B2 (en) | Modified immune cells and uses thereof | |
| RU2795148C2 (ru) | Конъюгат антитело-лекарственное средство, нагруженный бинарными токсинами, и его применение | |
| EP4610267A1 (en) | Cyclic dinucleotides and conjugates thereof with antibodies | |
| HK40085783A (en) | Antibody drug conjugate loaded with double toxins and application thereof | |
| Moore et al. | Quilty lesion FOXP3+ and TGF-Beta+ Regulatory T-Cells are associated with acceptance of heart allografts | |
| Zuckermann et al. | Peri-Operative Extracorporeal Photopheresis in High Risk Patients after Heart Transplantation |