JP2021526365A - 改善された標的化ｔ細胞療法 - Google Patents

改善された標的化ｔ細胞療法 Download PDF

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JP2021526365A
JP2021526365A JP2020564560A JP2020564560A JP2021526365A JP 2021526365 A JP2021526365 A JP 2021526365A JP 2020564560 A JP2020564560 A JP 2020564560A JP 2020564560 A JP2020564560 A JP 2020564560A JP 2021526365 A JP2021526365 A JP 2021526365A
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hla
cell
tumor
peptide
specific
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JP2021526365A5 (https=
Inventor
キャサリン メアリー ボラード，
キャサリン メアリー ボラード，
コンラッド ラッセル ワイ． クルス，
コンラッド ラッセル ワイ． クルス，
パトリック ハンリー，
パトリック ハンリー，
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Childrens National Medical Center Inc
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Childrens National Medical Center Inc
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    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K40/4242—Transcription factors, e.g. SOX or c-MYC
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    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
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    • C12N5/0602—Vertebrate cells
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    • C12N5/0636—T lymphocytes
    • C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
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    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
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JP2020564560A 2018-05-18 2019-05-20 改善された標的化ｔ細胞療法 Pending JP2021526365A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862673745P 2018-05-18 2018-05-18
US62/673,745 2018-05-18
PCT/US2019/033182 WO2019222760A1 (en) 2018-05-18 2019-05-20 Improved targeted t-cell therapy

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JP2021526365A true JP2021526365A (ja) 2021-10-07
JP2021526365A5 JP2021526365A5 (https=) 2022-05-30

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US (1) US20230002730A1 (https=)
EP (1) EP3796923A4 (https=)
JP (1) JP2021526365A (https=)
CN (1) CN112512538A (https=)
CA (1) CA3100775A1 (https=)
WO (1) WO2019222760A1 (https=)

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AU2013260132B2 (en) 2012-05-08 2017-12-14 The Johns Hopkins University Methods and compositions for infusion of transiently engrafting, selected populations of allogeneic lymphocytes to treat cancer
US20180072990A1 (en) * 2015-03-20 2018-03-15 Children's National Medical Center Generating virus or other antigen-specific t cells from a naïve t cell population
GB201604458D0 (en) 2016-03-16 2016-04-27 Immatics Biotechnologies Gmbh Peptides and combination of peptides for use in immunotherapy against cancers
DE102016123893A1 (de) 2016-12-08 2018-06-14 Immatics Biotechnologies Gmbh T-Zellrezeptoren mit verbesserter Bindung
CN110651189B (zh) 2017-03-03 2024-10-25 特雷斯生物有限公司 肽疫苗
MX2019015879A (es) * 2017-07-07 2020-02-07 Immatics Biotechnologies Gmbh Nuevos peptidos y nuevas combinacones de peptidos para el uso en la inmunoterapia contra el cancer de pulmon, incluyendo el nsclc, el sclc y otros canceres.
JP7642530B2 (ja) 2018-09-04 2025-03-10 トレオス バイオ リミテッド ペプチドワクチン
WO2020146434A2 (en) * 2019-01-07 2020-07-16 Children's National Medical Center Ex vivo activated t-lymphocytic compositions and methods of using the same
US20220160767A1 (en) * 2019-05-31 2022-05-26 Children's National Medical Center Cytokine cocktails for selective expansion of t cell subsets
JP7811013B2 (ja) * 2020-02-10 2026-02-04 ザ・ジョンズ・ホプキンス・ユニバーシティ 同種異系、腫瘍特異的なｃｄ４＋ ｔ細胞の注射移植を用いたがん免疫療法
CN114524870A (zh) * 2020-11-23 2022-05-24 香雪生命科学技术（广东）有限公司 源自于ssx2抗原的短肽
US20220257651A1 (en) * 2020-12-23 2022-08-18 Mana Therapeutics Methods and delivery of allogeneic cell products
EP4320435A1 (en) * 2021-04-09 2024-02-14 Achilles Therapeutics UK Limited Batch release assay for pharmaceutical products relating to t cell therapies
CN115677846A (zh) * 2021-07-27 2023-02-03 香雪生命科学技术（广东）有限公司 针对抗原ssx2的高亲和力t细胞受体
CN115819555A (zh) * 2021-09-17 2023-03-21 香雪生命科学技术（广东）有限公司 一种识别ssx2的高亲和力tcr
CN114478712B (zh) * 2022-03-29 2022-09-23 深圳吉诺因生物科技有限公司 Hpv抗原表位及其鉴定方法、应用
CN117946246B (zh) * 2023-02-23 2024-08-06 暨南大学 一种识别mage-a3抗原短肽的t细胞受体及其应用
CN117402218B (zh) * 2023-12-15 2024-02-20 上海惠盾因泰生物科技有限公司 一种Survivin阳性肿瘤的个体化树突状细胞疫苗及其制备方法

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EP3796923A1 (en) 2021-03-31
US20230002730A1 (en) 2023-01-05
CA3100775A1 (en) 2019-11-21
WO2019222760A1 (en) 2019-11-21
EP3796923A4 (en) 2022-03-09

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