CN112512538A - 改进的靶向t细胞疗法 - Google Patents

改进的靶向t细胞疗法 Download PDF

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CN112512538A
CN112512538A CN201980046752.2A CN201980046752A CN112512538A CN 112512538 A CN112512538 A CN 112512538A CN 201980046752 A CN201980046752 A CN 201980046752A CN 112512538 A CN112512538 A CN 112512538A
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hla
cell
tumor
peptides
specific
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Chinese (zh)
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C·M·博拉德
C·R·Y·克鲁兹
P·汉利
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Childrens National Medical Center Inc
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Childrens National Medical Center Inc
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CN201980046752.2A 2018-05-18 2019-05-20 改进的靶向t细胞疗法 Pending CN112512538A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862673745P 2018-05-18 2018-05-18
US62/673,745 2018-05-18
PCT/US2019/033182 WO2019222760A1 (en) 2018-05-18 2019-05-20 Improved targeted t-cell therapy

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CN112512538A true CN112512538A (zh) 2021-03-16

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US (1) US20230002730A1 (https=)
EP (1) EP3796923A4 (https=)
JP (1) JP2021526365A (https=)
CN (1) CN112512538A (https=)
CA (1) CA3100775A1 (https=)
WO (1) WO2019222760A1 (https=)

Cited By (6)

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CN110785183A (zh) * 2017-07-07 2020-02-11 伊玛提克斯生物技术有限公司 用于肺癌(包括nsclc、sclc和其他癌症)免疫治疗的新型肽和肽组合物
CN114478712A (zh) * 2022-03-29 2022-05-13 深圳吉诺因生物科技有限公司 Hpv抗原表位及其鉴定方法、应用
WO2023005859A1 (zh) * 2021-07-27 2023-02-02 香雪生命科学技术（广东）有限公司 针对抗原ssx2的高亲和力t细胞受体
WO2023040946A1 (zh) * 2021-09-17 2023-03-23 香雪生命科学技术（广东）有限公司 一种识别ssx2的高亲和力tcr
CN117402218A (zh) * 2023-12-15 2024-01-16 上海惠盾因泰生物科技有限公司 一种Survivin阳性肿瘤的个体化树突状细胞疫苗及其制备方法
CN117946246A (zh) * 2023-02-23 2024-04-30 暨南大学 一种识别mage-a3抗原短肽的t细胞受体及其应用

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US12188004B2 (en) 2012-05-08 2025-01-07 The Johns Hopkins University Cancer immunotherapy using transfusions of allogeneic, tumor-specific CD4+ T cells
AU2013260132B2 (en) 2012-05-08 2017-12-14 The Johns Hopkins University Methods and compositions for infusion of transiently engrafting, selected populations of allogeneic lymphocytes to treat cancer
US20180072990A1 (en) * 2015-03-20 2018-03-15 Children's National Medical Center Generating virus or other antigen-specific t cells from a naïve t cell population
GB201604458D0 (en) 2016-03-16 2016-04-27 Immatics Biotechnologies Gmbh Peptides and combination of peptides for use in immunotherapy against cancers
DE102016123893A1 (de) 2016-12-08 2018-06-14 Immatics Biotechnologies Gmbh T-Zellrezeptoren mit verbesserter Bindung
CN110651189B (zh) 2017-03-03 2024-10-25 特雷斯生物有限公司 肽疫苗
JP7642530B2 (ja) 2018-09-04 2025-03-10 トレオス バイオ リミテッド ペプチドワクチン
WO2020146434A2 (en) * 2019-01-07 2020-07-16 Children's National Medical Center Ex vivo activated t-lymphocytic compositions and methods of using the same
US20220160767A1 (en) * 2019-05-31 2022-05-26 Children's National Medical Center Cytokine cocktails for selective expansion of t cell subsets
JP7811013B2 (ja) * 2020-02-10 2026-02-04 ザ・ジョンズ・ホプキンス・ユニバーシティ 同種異系、腫瘍特異的なｃｄ４＋ ｔ細胞の注射移植を用いたがん免疫療法
CN114524870A (zh) * 2020-11-23 2022-05-24 香雪生命科学技术（广东）有限公司 源自于ssx2抗原的短肽
US20220257651A1 (en) * 2020-12-23 2022-08-18 Mana Therapeutics Methods and delivery of allogeneic cell products
EP4320435A1 (en) * 2021-04-09 2024-02-14 Achilles Therapeutics UK Limited Batch release assay for pharmaceutical products relating to t cell therapies

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WO2017197347A1 (en) * 2016-05-12 2017-11-16 Adicet Bio, Inc. METHODS FOR SELECTIVE EXPANSION OF γδ T-CELL POPULATIONS AND COMPOSITIONS THEREOF
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US20180072990A1 (en) * 2015-03-20 2018-03-15 Children's National Medical Center Generating virus or other antigen-specific t cells from a naïve t cell population
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CN101166759A (zh) * 2005-04-26 2008-04-23 伊玛提克斯生物技术有限公司 来自癌胚胎抗原-未成熟层粘连蛋白受体蛋白的t细胞表位及其医药用途
WO2011028531A1 (en) * 2009-08-24 2011-03-10 Baylor College Of Medicine Generation of ctl lines with specificity against multiple tumor antigens or multiple viruses
CN106414500A (zh) * 2013-11-07 2017-02-15 纪念斯隆-凯特琳癌症中心 抗-wt1/hla双特异性抗体
US20170335290A1 (en) * 2014-10-31 2017-11-23 Baylor College Of Medicine Survivin specific t-cell receptor targeting tumor but not t cells
WO2017197347A1 (en) * 2016-05-12 2017-11-16 Adicet Bio, Inc. METHODS FOR SELECTIVE EXPANSION OF γδ T-CELL POPULATIONS AND COMPOSITIONS THEREOF

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110785183A (zh) * 2017-07-07 2020-02-11 伊玛提克斯生物技术有限公司 用于肺癌(包括nsclc、sclc和其他癌症)免疫治疗的新型肽和肽组合物
WO2023005859A1 (zh) * 2021-07-27 2023-02-02 香雪生命科学技术（广东）有限公司 针对抗原ssx2的高亲和力t细胞受体
WO2023040946A1 (zh) * 2021-09-17 2023-03-23 香雪生命科学技术（广东）有限公司 一种识别ssx2的高亲和力tcr
CN114478712A (zh) * 2022-03-29 2022-05-13 深圳吉诺因生物科技有限公司 Hpv抗原表位及其鉴定方法、应用
CN114478712B (zh) * 2022-03-29 2022-09-23 深圳吉诺因生物科技有限公司 Hpv抗原表位及其鉴定方法、应用
WO2023184862A1 (zh) * 2022-03-29 2023-10-05 深圳吉诺因生物科技有限公司 Hpv抗原表位及其鉴定方法、应用
CN117946246A (zh) * 2023-02-23 2024-04-30 暨南大学 一种识别mage-a3抗原短肽的t细胞受体及其应用
CN117402218A (zh) * 2023-12-15 2024-01-16 上海惠盾因泰生物科技有限公司 一种Survivin阳性肿瘤的个体化树突状细胞疫苗及其制备方法
CN117402218B (zh) * 2023-12-15 2024-02-20 上海惠盾因泰生物科技有限公司 一种Survivin阳性肿瘤的个体化树突状细胞疫苗及其制备方法

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