JP2021525807A5 - - Google Patents

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Publication number
JP2021525807A5
JP2021525807A5 JP2021517169A JP2021517169A JP2021525807A5 JP 2021525807 A5 JP2021525807 A5 JP 2021525807A5 JP 2021517169 A JP2021517169 A JP 2021517169A JP 2021517169 A JP2021517169 A JP 2021517169A JP 2021525807 A5 JP2021525807 A5 JP 2021525807A5
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JP
Japan
Prior art keywords
ubiquitin
factor
biomolecule
protein
terminus
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Application number
JP2021517169A
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English (en)
Japanese (ja)
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JP7402864B2 (ja
JP2021525807A (ja
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Priority claimed from PCT/KR2019/006376 external-priority patent/WO2019231208A1/ko
Publication of JP2021525807A publication Critical patent/JP2021525807A/ja
Publication of JP2021525807A5 publication Critical patent/JP2021525807A5/ja
Application granted granted Critical
Publication of JP7402864B2 publication Critical patent/JP7402864B2/ja
Active legal-status Critical Current
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JP2021517169A 2018-05-28 2019-05-28 ポリユビキチンリンカーに結合された線形多機能性マルチマー生体分子及びその用途 Active JP7402864B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR10-2018-0060502 2018-05-28
KR20180060502 2018-05-28
PCT/KR2019/006376 WO2019231208A1 (ko) 2018-05-28 2019-05-28 폴리유비퀴틴 링커에 결합된 선형 다기능성 멀티머 생체분자 및 이의 용도

Publications (3)

Publication Number Publication Date
JP2021525807A JP2021525807A (ja) 2021-09-27
JP2021525807A5 true JP2021525807A5 (enExample) 2022-09-06
JP7402864B2 JP7402864B2 (ja) 2023-12-21

Family

ID=68697037

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021517169A Active JP7402864B2 (ja) 2018-05-28 2019-05-28 ポリユビキチンリンカーに結合された線形多機能性マルチマー生体分子及びその用途

Country Status (7)

Country Link
US (1) US20210347827A1 (enExample)
EP (1) EP3805256A4 (enExample)
JP (1) JP7402864B2 (enExample)
KR (2) KR20190135393A (enExample)
CN (1) CN112204046A (enExample)
AU (2) AU2019276622A1 (enExample)
WO (1) WO2019231208A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ788436A (en) * 2019-11-27 2025-08-29 Onegene Biotechnology Inc Multifunctional multispecific multimeric biomolecule polymer having prolonged in-vivo duration
AU2021264869B2 (en) * 2020-04-29 2025-09-11 Onegene Biotechnology Inc. Novel protein conjugate, and use thereof for preventing or treating nonalcoholic steatohepatitis, obesity and diabetes
CN115678985B (zh) * 2022-10-26 2025-07-29 华南农业大学 March5在鉴别猪对蓝耳病毒易感性及制备药物中的应用
CN117045590B (zh) * 2023-08-14 2026-07-14 钱望(浙江)生物科技有限责任公司 一种温敏性抗菌抗氧化凝胶及其制备方法
CN119876239A (zh) * 2025-01-27 2025-04-25 吉林大学 拟南芥AtUPL5基因在提高植物抗性方面的应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7354722B1 (en) * 1999-06-11 2008-04-08 Signal Pharmaceuticals Modulators of Smurf and BMP/TGFβ signaling pathways
AU2002257243A1 (en) * 2001-05-04 2002-11-18 Cornell Research Foundation, Inc. Rapidly cleavable sumo fusion protein expression system for difficult to express proteins
DE10324447A1 (de) * 2003-05-28 2004-12-30 Scil Proteins Gmbh Generierung künstlicher Bindungsproteine auf der Grundlage von Ubiquitin
AU2004254600A1 (en) * 2003-06-26 2005-01-13 Lifesensors, Inc. Methods and compositions for enhanced protein expression and purification
KR20050050824A (ko) 2003-11-26 2005-06-01 세메스 주식회사 베이크 장치에서의 웨이퍼 안착 상태를 감지하여 인터락을제어하기 위한 시스템 및 그의 제어 방법
DE102004049479A1 (de) * 2004-10-11 2006-04-13 Scil Proteins Gmbh Proteinkonjugate zur Verwendung in Therapie, Diagnose und Chromatographie
KR100621354B1 (ko) * 2005-06-14 2006-09-08 광주과학기술원 유비퀴틴을 이용한 아밀로이드-베타 펩티드의 제조방법
EP1973948B1 (en) * 2005-12-15 2015-02-11 Genentech, Inc. Methods and compositions for targeting polyubiquitin
WO2009009773A1 (en) * 2007-07-11 2009-01-15 The Johns Hopkins University Use of otubain enzyme to cleave lysine-48-linked polyubiquitin
BR112012014417B1 (pt) * 2009-12-14 2021-11-09 Scil Proteins Gmbh Proteínas ubiquitinas modificadas tendo uma atividade de ligação específica para o extradomínio b de fibronectina
US20130065272A1 (en) * 2010-03-24 2013-03-14 Medical Research Council Synthesis of Site Specifically-Linked Ubiquitin
EP2825549B1 (en) * 2012-03-16 2018-10-10 F. Hoffmann-La Roche SA Engineered conformationally-stabilized proteins
KR101911438B1 (ko) * 2012-10-31 2018-10-24 삼성전자주식회사 이중 특이 항원 결합 단백질 복합체 및 이중 특이 항체의 제조 방법
US20160186156A1 (en) * 2013-08-04 2016-06-30 Yeda Research And Development Co., Ltd. Artificial cellulosomes comprising multiple scaffolds and uses thereof in biomass degradation
TWI569816B (zh) 2014-04-18 2017-02-11 林信湧 一種用於治療痛風之吸入式醫藥組成物及其備製方法
KR20170025040A (ko) * 2015-08-27 2017-03-08 한국기초과학지원연구원 염 용리 가능한 k48 폴리-유비퀴틴 사슬 특이 친화성 컬럼 및 이의 용도

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