JP2021525791A - 新たな心不全治療用医薬の使用 - Google Patents

新たな心不全治療用医薬の使用 Download PDF

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JP2021525791A
JP2021525791A JP2021507507A JP2021507507A JP2021525791A JP 2021525791 A JP2021525791 A JP 2021525791A JP 2021507507 A JP2021507507 A JP 2021507507A JP 2021507507 A JP2021507507 A JP 2021507507A JP 2021525791 A JP2021525791 A JP 2021525791A
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Prior art keywords
sacubitril
valsartan
molar ratio
patients
heart failure
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JP2021507507A
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English (en)
Japanese (ja)
Inventor
ブティリン，ドミトロ
ファーバー，フィリップ
ノエ，アデル
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ノバルティス アーゲー
ノバルティス アーゲー
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Publication of JP2021525791A publication Critical patent/JP2021525791A/ja
Priority to JP2022090079A priority Critical patent/JP2022116278A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225—Polycarboxylic acids

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2021507507A 2018-08-23 2019-08-22 新たな心不全治療用医薬の使用 Pending JP2021525791A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022090079A JP2022116278A (ja) 2018-08-23 2022-06-02 新たな心不全治療用医薬の使用

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP18190588 2018-08-23
EP18190588.6 2018-08-23
EP18199733 2018-10-10
EP18199733.9 2018-10-10
PCT/IB2019/057081 WO2020039386A1 (en) 2018-08-23 2019-08-22 New pharmaceutical use for the treatment of heart failure

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JP2022090079A Division JP2022116278A (ja) 2018-08-23 2022-06-02 新たな心不全治療用医薬の使用

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JP2021525791A true JP2021525791A (ja) 2021-09-27

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JP2021507507A Pending JP2021525791A (ja) 2018-08-23 2019-08-22 新たな心不全治療用医薬の使用
JP2022090079A Pending JP2022116278A (ja) 2018-08-23 2022-06-02 新たな心不全治療用医薬の使用

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US (1) US20210177803A1 (https=)
EP (1) EP3840746A1 (https=)
JP (2) JP2021525791A (https=)
KR (1) KR20210032437A (https=)
CA (1) CA3110152A1 (https=)
WO (1) WO2020039386A1 (https=)

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KR20240173982A (ko) 2023-06-07 2024-12-16 인제대학교 산학협력단 세레블론 단백질 또는 상기 단백질을 코딩하는 유전자를 유효성분으로 포함하는 심부전 진단용 바이오마커 조성물 및 치료용 약학 조성물

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Also Published As

Publication number Publication date
US20210177803A1 (en) 2021-06-17
KR20210032437A (ko) 2021-03-24
WO2020039386A1 (en) 2020-02-27
CA3110152A1 (en) 2020-02-27
EP3840746A1 (en) 2021-06-30
JP2022116278A (ja) 2022-08-09

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