JP2021524248A5 - - Google Patents
Info
- Publication number
- JP2021524248A5 JP2021524248A5 JP2020565274A JP2020565274A JP2021524248A5 JP 2021524248 A5 JP2021524248 A5 JP 2021524248A5 JP 2020565274 A JP2020565274 A JP 2020565274A JP 2020565274 A JP2020565274 A JP 2020565274A JP 2021524248 A5 JP2021524248 A5 JP 2021524248A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- chimeric antigen
- receptor
- amino acid
- antigen receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2018901782A AU2018901782A0 (en) | 2018-05-21 | Chimeric Antigen Receptors with Modified Linker Domain and uses thereof | |
| AU2018901782 | 2018-05-21 | ||
| PCT/AU2019/050487 WO2019222796A1 (en) | 2018-05-21 | 2019-05-20 | Chimeric antigen receptors with modified linker domains and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021524248A JP2021524248A (ja) | 2021-09-13 |
| JP2021524248A5 true JP2021524248A5 (https=) | 2022-05-16 |
Family
ID=68615492
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020565274A Pending JP2021524248A (ja) | 2018-05-21 | 2019-05-20 | 修飾されたリンカードメインを有するキメラ抗原受容体およびその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220089718A1 (https=) |
| EP (1) | EP3797164A4 (https=) |
| JP (1) | JP2021524248A (https=) |
| KR (1) | KR20210013691A (https=) |
| CN (1) | CN112166193A (https=) |
| AU (1) | AU2019275479B2 (https=) |
| BR (1) | BR112020023489A8 (https=) |
| CA (1) | CA3099712A1 (https=) |
| MX (1) | MX2020012445A (https=) |
| SG (1) | SG11202010451QA (https=) |
| WO (1) | WO2019222796A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12121539B2 (en) | 2015-09-11 | 2024-10-22 | Biosceptre (Aust) Pty Ltd | Chimeric antigen receptors and uses thereof |
| CN114787351A (zh) * | 2019-10-15 | 2022-07-22 | 加利福尼亚大学董事会 | 通过Fc隔离的移植细胞保护 |
| CN111944062B (zh) * | 2019-12-09 | 2023-11-07 | 深圳市体内生物医药科技有限公司 | 一种识别Fc片段的嵌合抗原受体及其应用 |
| CN115362172A (zh) * | 2020-02-12 | 2022-11-18 | Sab有限责任公司 | 抗胸腺细胞球蛋白 |
| EP4204005A1 (en) | 2020-08-31 | 2023-07-05 | Sab, Llc | Ungulate-derived polyclonal immunoglobulin specific for coronavirus protein and uses thereof |
| EP4304610A4 (en) * | 2021-03-11 | 2025-03-05 | Biosceptre (Aust) Pty Ltd | Novel cell therapy system |
| US20240368282A1 (en) * | 2021-09-01 | 2024-11-07 | Biosceptre (Aust) Pty Ltd | Methods and compositions for stimulating immune activity |
| EP4476267A4 (en) * | 2022-02-11 | 2026-01-07 | Fred Hutchinson Cancer Center | CHIMERIC ANTIGENIC RECEPTORS BINDING TO STEAP1 |
| JP2025531675A (ja) * | 2022-09-14 | 2025-09-25 | バイオセプター （オースト） プロプライエタリー・リミテッド | 操作された免疫細胞の富化 |
| CN120166997A (zh) * | 2022-09-14 | 2025-06-17 | 生物权威(澳大利亚)有限责任公司 | 检测免疫细胞的方法 |
| CN120187461A (zh) * | 2022-09-14 | 2025-06-20 | 生物权威(澳大利亚)有限责任公司 | 免疫细胞的体内检测 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4579821A (en) | 1981-11-23 | 1986-04-01 | University Patents, Inc. | Control of DNA sequence transcription |
| US4601978A (en) | 1982-11-24 | 1986-07-22 | The Regents Of The University Of California | Mammalian metallothionein promoter system |
| US4940661A (en) | 1984-05-17 | 1990-07-10 | Genentech, Inc. | Metallothionein transcription control sequences and use thereof |
| US5512483A (en) | 1993-05-21 | 1996-04-30 | Mcgill University | Expression vectors responsive to steroid hormones |
| US5464758A (en) | 1993-06-14 | 1995-11-07 | Gossen; Manfred | Tight control of gene expression in eucaryotic cells by tetracycline-responsive promoters |
| PL323587A1 (en) | 1995-05-26 | 1998-04-14 | Zeneca Ltd | Gene changing-over system including edisone receptor |
| US5851796A (en) | 1995-06-07 | 1998-12-22 | Yale University | Autoregulatory tetracycline-regulated system for inducible gene expression in eucaryotes |
| AU4533300A (en) * | 1999-09-16 | 2001-04-17 | Liangqi Zhang | A pressure-reducing diaphragm of carburettor |
| CN100497386C (zh) | 2001-09-03 | 2009-06-10 | 因特里特有限公司 | 非功能性p2x7受体的抗体及其应用 |
| JP2008511286A (ja) | 2004-06-02 | 2008-04-17 | ダイアテック・ピーティワイ・リミテッド | サメ類のＩｇＮＡＲドメインに基づく結合成分 |
| JP2010505426A (ja) | 2006-10-10 | 2010-02-25 | バイオスセプター インターナショナル リミテッド | 非機能性ｐ２ｘ７受容体に対する抗体を産生するハイブリドーマ |
| WO2008043146A1 (en) | 2006-10-10 | 2008-04-17 | Biosceptre International Limited | Antibodies against non functional p2x7 receptor |
| ES2619681T3 (es) | 2007-09-14 | 2017-06-26 | Biosceptre (Aust) Pty Ltd | Novedosos epítopos P2X7 |
| CN102143978B (zh) | 2008-07-04 | 2015-02-18 | 生物权威国际有限公司 | 抗p2x7肽和表位 |
| EP2467404B1 (en) | 2009-08-20 | 2015-09-30 | Biosceptre International Limited | Anti p2x7 receptor antibodies and fragments thereof |
| WO2011075789A1 (en) | 2009-12-24 | 2011-06-30 | Biosceptre International Limited | Antibodies to non-functional oligomeric p2x7 receptors |
| ES2602743T3 (es) * | 2010-09-08 | 2017-02-22 | Chemotherapeutisches Forschungsinstitut Georg-Speyer-Haus | Receptores de antígenos quiméricos con una región bisagra optimizada |
| EP2646461A2 (en) | 2010-12-03 | 2013-10-09 | Cyclogenix Ltd | VARIANTS OF igNAR |
| EP2990416B1 (en) * | 2014-08-29 | 2018-06-20 | GEMoaB Monoclonals GmbH | Universal chimeric antigen receptor expressing immune cells for targeting of diverse multiple antigens and method of manufacturing the same and use of the same for treatment of cancer, infections and autoimmune disorders |
| BR112017005631A2 (pt) * | 2014-09-19 | 2018-06-26 | City Of Hope | células t com receptor de antígeno coestimulador quimérico direcionadas à il13ra2 |
| KR102558502B1 (ko) * | 2014-12-05 | 2023-07-20 | 시티 오브 호프 | Ｃｓ1 표적화된 키메라 항원 수용체-변형된 ｔ 세포 |
| WO2016123143A1 (en) * | 2015-01-26 | 2016-08-04 | The University Of Chicago | CAR T-CELLS RECOGNIZING CANCER-SPECIFIC IL 13Rα2 |
| US12121539B2 (en) * | 2015-09-11 | 2024-10-22 | Biosceptre (Aust) Pty Ltd | Chimeric antigen receptors and uses thereof |
| WO2017181001A1 (en) * | 2016-04-15 | 2017-10-19 | Trustees Of Dartmouth College | High affinity b7-h6 antibodies and antibody fragments |
| WO2018017649A1 (en) * | 2016-07-19 | 2018-01-25 | Unum Therapeutics Inc. | Use of antibody-coupled t cell receptor (actr) with multiple anti-cancer antibodies in cancer treatment |
| US20190263928A1 (en) * | 2016-09-30 | 2019-08-29 | Baylor College Of Medicine | Adaptive chimeric antigen receptor t-cell design |
| EP3315511A1 (en) * | 2016-10-29 | 2018-05-02 | Miltenyi Biotec GmbH | Adapter chimeric antigen receptor expressing cells for targeting of multiple antigens |
-
2019
- 2019-05-20 CN CN201980034413.2A patent/CN112166193A/zh active Pending
- 2019-05-20 US US17/057,060 patent/US20220089718A1/en active Pending
- 2019-05-20 MX MX2020012445A patent/MX2020012445A/es unknown
- 2019-05-20 JP JP2020565274A patent/JP2021524248A/ja active Pending
- 2019-05-20 SG SG11202010451QA patent/SG11202010451QA/en unknown
- 2019-05-20 CA CA3099712A patent/CA3099712A1/en active Pending
- 2019-05-20 KR KR1020207033662A patent/KR20210013691A/ko not_active Ceased
- 2019-05-20 WO PCT/AU2019/050487 patent/WO2019222796A1/en not_active Ceased
- 2019-05-20 AU AU2019275479A patent/AU2019275479B2/en active Active
- 2019-05-20 BR BR112020023489A patent/BR112020023489A8/pt unknown
- 2019-05-20 EP EP19808128.3A patent/EP3797164A4/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2021524248A5 (https=) | ||
| US20240228636A1 (en) | mAb-DRIVEN CHIMERIC ANTIGEN RECEPTOR SYSTEMS FOR SORTING/DEPLETING ENGINEERED IMMUNE CELLS | |
| JP7797198B2 (ja) | ヒトｐｄ－１に対する二機能性分子 | |
| JP7807234B2 (ja) | 二機能性抗ｐｄ－１／ｉｌ－７分子 | |
| JP7675012B2 (ja) | 二機能性抗ｐｄ－１／ｓｉｒｐａ分子 | |
| BR112021011982A2 (pt) | Anticorpo anti-humano-pd-1 humanizado | |
| AU2019299439A1 (en) | Chimeric receptors in combination with trans metabolism molecules enhancing glucose import and therapeutic uses thereof | |
| CA3111706A1 (en) | Chimeric receptor polypeptides in combination with trans metabolism molecules modulating intracellular lactate concentrations and therapeutic uses thereof | |
| KR20240099224A (ko) | 항원 결합 폴리펩티드, 항원 결합 폴리펩티드 복합체 및 이의 사용 방법 | |
| AU2022288574A9 (en) | Multispecific antibodies binding to cd20, nkp46, cd16 and conjugated to il-2 | |
| JP7319250B2 (ja) | Ｓｔｒｅｐ－タグ特異的結合タンパク質およびその使用 | |
| KR20230162013A (ko) | Nk 세포 관여를 위해 사이토카인에 융합된 nkp46-결합 부위, 암 항원 결합 부위를 포함하는 다중특이적 단백질 | |
| Mohammadi et al. | Immunotherapy For Researchers | |
| JP2020528765A5 (https=) | ||
| KR20240005741A (ko) | 특성이 향상된 이작용성 분자용 신규한 스캐폴드 | |
| JP7558534B2 (ja) | Ｃｄ１３７アゴニスト性抗体とその使用 | |
| WO2022258678A1 (en) | Multispecific proteins binding to nkp30, a cytokine receptor, a tumour antigen and cd16a | |
| WO2022258691A1 (en) | Multispecific proteins binding to nkg2d, a cytokine receptor, a tumour antigen and cd16a | |
| US20230002488A1 (en) | Guidance and navigation control proteins and method of making and using thereof | |
| US20250101104A1 (en) | Bispecific molecule with tunable affinity to a targeted antigen | |
| JP2026506471A (ja) | 組み換えＦｃドメイン－ＩＬ２バリアントポリペプチド及び膜アンカー抗原結合ポリペプチドとの併用療法 | |
| WO2024028386A1 (en) | Multifunctional molecule directed against cd28 | |
| JP2022547650A (ja) | ヒトプログラム細胞死受容体ｐｄ－１に対する抗体 | |
| JP2025530110A (ja) | 二重特異性ポリペプチド及びその使用 | |
| WO2024238287A1 (en) | Dual blocking and chimeric cytokine receptor |