JP2021523724A5 - - Google Patents
Info
- Publication number
- JP2021523724A5 JP2021523724A5 JP2020564225A JP2020564225A JP2021523724A5 JP 2021523724 A5 JP2021523724 A5 JP 2021523724A5 JP 2020564225 A JP2020564225 A JP 2020564225A JP 2020564225 A JP2020564225 A JP 2020564225A JP 2021523724 A5 JP2021523724 A5 JP 2021523724A5
- Authority
- JP
- Japan
- Prior art keywords
- fusosome
- cells
- fusosomes
- receptor
- specific
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024081800A JP7815327B2 (ja) | 2018-05-15 | 2024-05-20 | フソソーム組成物およびその使用 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862671838P | 2018-05-15 | 2018-05-15 | |
| US62/671,838 | 2018-05-15 | ||
| US201862695529P | 2018-07-09 | 2018-07-09 | |
| US62/695,529 | 2018-07-09 | ||
| PCT/US2019/032488 WO2019222403A2 (en) | 2018-05-15 | 2019-05-15 | Fusosome compositions and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024081800A Division JP7815327B2 (ja) | 2018-05-15 | 2024-05-20 | フソソーム組成物およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021523724A JP2021523724A (ja) | 2021-09-09 |
| JP2021523724A5 true JP2021523724A5 (https=) | 2023-11-29 |
| JP7568513B2 JP7568513B2 (ja) | 2024-10-16 |
Family
ID=67303499
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020564225A Active JP7568513B2 (ja) | 2018-05-15 | 2019-05-15 | フソソーム組成物およびその使用 |
| JP2024081800A Active JP7815327B2 (ja) | 2018-05-15 | 2024-05-20 | フソソーム組成物およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024081800A Active JP7815327B2 (ja) | 2018-05-15 | 2024-05-20 | フソソーム組成物およびその使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20210228627A1 (https=) |
| EP (1) | EP3793570A2 (https=) |
| JP (2) | JP7568513B2 (https=) |
| KR (2) | KR20260042239A (https=) |
| CN (1) | CN112367973A (https=) |
| AU (1) | AU2019269593A1 (https=) |
| BR (1) | BR112020023015A2 (https=) |
| CA (1) | CA3099497A1 (https=) |
| IL (1) | IL278665B2 (https=) |
| MX (2) | MX2020012295A (https=) |
| SG (1) | SG11202011015QA (https=) |
| WO (1) | WO2019222403A2 (https=) |
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|---|---|---|---|---|
| US9228207B2 (en) | 2013-09-06 | 2016-01-05 | President And Fellows Of Harvard College | Switchable gRNAs comprising aptamers |
| US11111505B2 (en) | 2016-03-19 | 2021-09-07 | Exuma Biotech, Corp. | Methods and compositions for transducing lymphocytes and regulating the activity thereof |
| US12590321B2 (en) | 2016-03-19 | 2026-03-31 | Exuma Biotech Corp. | Methods and compositions for genetically modifying and expanding lymphocytes and regulating the activity thereof |
| US11325948B2 (en) | 2016-03-19 | 2022-05-10 | Exuma Biotech Corp. | Methods and compositions for genetically modifying lymphocytes to express polypeptides comprising the intracellular domain of MPL |
| EP3235908A1 (en) | 2016-04-21 | 2017-10-25 | Ecole Normale Superieure De Lyon | Methods for selectively modulating the activity of distinct subtypes of cells |
| CA3062426A1 (en) | 2017-05-08 | 2018-11-15 | Flagship Pioneering Innovations V, Inc. | Compositions for facilitating membrane fusion and uses thereof |
| CN112955174A (zh) | 2018-07-09 | 2021-06-11 | 旗舰先锋创新V股份有限公司 | 融合剂脂质体组合物和其用途 |
| US12522807B2 (en) | 2018-07-09 | 2026-01-13 | The Broad Institute, Inc. | RNA programmable epigenetic RNA modifiers and uses thereof |
| CN113631718A (zh) | 2018-11-14 | 2021-11-09 | 旗舰先锋创新V股份有限公司 | 用于特定隔室货物递送的组合物和方法 |
| AU2019378883A1 (en) * | 2018-11-14 | 2021-06-03 | Flagship Pioneering Innovations V, Inc. | Fusosome compositions for T cell delivery |
| US12351837B2 (en) | 2019-01-23 | 2025-07-08 | The Broad Institute, Inc. | Supernegatively charged proteins and uses thereof |
| WO2020191233A1 (en) | 2019-03-19 | 2020-09-24 | The Broad Institute, Inc. | Methods and compositions for editing nucleotide sequences |
| US12473543B2 (en) | 2019-04-17 | 2025-11-18 | The Broad Institute, Inc. | Adenine base editors with reduced off-target effects |
| WO2020252455A1 (en) * | 2019-06-13 | 2020-12-17 | The General Hospital Corporation | Engineered human-endogenous virus-like particles and methods of use thereof for delivery to cells |
| CA3152525A1 (en) | 2019-09-03 | 2021-03-11 | Sana Biotechnology, Inc. | Cd24-associated particles and related methods and uses thereof |
| CN114828885A (zh) * | 2019-12-10 | 2022-07-29 | 瑞普利金公司 | 制备病毒载体的方法 |
| CA3178308A1 (en) * | 2020-03-31 | 2021-10-07 | Sana Biotechnology, Inc. | Targeted lipid particles and compositions and uses thereof |
| CA3189601A1 (en) | 2020-07-24 | 2022-01-27 | The General Hospital Corporation | Enhanced virus-like particles and methods of use thereof for delivery to cells |
| WO2022055894A1 (en) * | 2020-09-08 | 2022-03-17 | The Regents Of The University Of California | Sars-cov-2 spike glycoprotein for virus generation and pseudotyping |
| MX2023008081A (es) * | 2021-01-11 | 2023-09-12 | Sana Biotechnology Inc | Uso de vectores virales dirigidos a cd8. |
| EP4298228A4 (en) * | 2021-02-23 | 2025-09-24 | Mayo Found Medical Education & Res | Genetically engineered hemagglutinin and fusion polypeptides from canine distemper virus |
| KR20240028975A (ko) | 2021-04-08 | 2024-03-05 | 사나 바이오테크놀로지, 인크. | Cd8-특이적 항체 구조체들 및 이의 조성물 |
| JP2024521811A (ja) | 2021-05-28 | 2024-06-04 | サナ バイオテクノロジー,インコーポレイテッド | 短縮型ヒヒ内在性レトロウイルス(BaEV)エンベロープ糖タンパク質を含む脂質粒子、ならびに関連する方法及び使用 |
| EP4381081A1 (en) | 2021-08-04 | 2024-06-12 | Sana Biotechnology, Inc. | Use of cd4-targeted viral vectors |
| CN114032239B (zh) * | 2021-10-28 | 2024-06-21 | 北京美康基免生物科技有限公司 | 一种组织特异启动子及其应用 |
| EP4426828A1 (en) | 2021-11-01 | 2024-09-11 | Tome Biosciences, Inc. | Single construct platform for simultaneous delivery of gene editing machinery and nucleic acid cargo |
| EP4433579A4 (en) * | 2021-11-18 | 2026-03-18 | Broad Inst Inc | Retargeted retroviral vectors resistant to vaccine-induced neutralization and compositions or methods of use thereof |
| US20250059239A1 (en) | 2021-12-17 | 2025-02-20 | Sana Biotechnology, Inc. | Modified paramyxoviridae fusion glycoproteins |
| WO2023115041A1 (en) | 2021-12-17 | 2023-06-22 | Sana Biotechnology, Inc. | Modified paramyxoviridae attachment glycoproteins |
| EP4463135A2 (en) * | 2022-01-10 | 2024-11-20 | Sana Biotechnology, Inc. | Methods of ex vivo dosing and administration of lipid particles or viral vectors and related systems and uses |
| EP4472646A1 (en) | 2022-02-01 | 2024-12-11 | Sana Biotechnology, Inc. | Cd3-targeted lentiviral vectors and uses thereof |
| WO2023150647A1 (en) | 2022-02-02 | 2023-08-10 | Sana Biotechnology, Inc. | Methods of repeat dosing and administration of lipid particles or viral vectors and related systems and uses |
| WO2023193015A1 (en) | 2022-04-01 | 2023-10-05 | Sana Biotechnology, Inc. | Cytokine receptor agonist and viral vector combination therapies |
| WO2023225670A2 (en) | 2022-05-20 | 2023-11-23 | Tome Biosciences, Inc. | Ex vivo programmable gene insertion |
| WO2024020587A2 (en) | 2022-07-22 | 2024-01-25 | Tome Biosciences, Inc. | Pleiopluripotent stem cell programmable gene insertion |
| US20260055146A1 (en) | 2022-08-24 | 2026-02-26 | Sana Biotechnology, Inc. | Delivery of heterologous proteins |
| WO2024064838A1 (en) | 2022-09-21 | 2024-03-28 | Sana Biotechnology, Inc. | Lipid particles comprising variant paramyxovirus attachment glycoproteins and uses thereof |
| WO2024081820A1 (en) | 2022-10-13 | 2024-04-18 | Sana Biotechnology, Inc. | Viral particles targeting hematopoietic stem cells |
| WO2024119157A1 (en) | 2022-12-02 | 2024-06-06 | Sana Biotechnology, Inc. | Lipid particles with cofusogens and methods of producing and using the same |
| WO2024220560A1 (en) | 2023-04-18 | 2024-10-24 | Sana Biotechnology, Inc. | Engineered protein g fusogens and related lipid particles and methods thereof |
| EP4698666A1 (en) | 2023-04-18 | 2026-02-25 | Sana Biotechnology, Inc. | Universal protein g fusogens and adapter systems thereof and related lipid particles and uses |
| EP4716750A1 (en) | 2023-05-23 | 2026-04-01 | Sana Biotechnology, Inc. | Tandem fusogens and related lipid particles |
| WO2025184529A1 (en) | 2024-03-01 | 2025-09-04 | Sana Biotechnology, Inc. | Viral particles with fusogen display and related compositions and methods |
| WO2025224182A2 (en) | 2024-04-23 | 2025-10-30 | Basecamp Research Ltd | Single construct platform for simultaneous delivery of gene editing machinery and nucleic acid cargo |
Family Cites Families (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL78703A (en) | 1985-05-10 | 1993-02-21 | Benzon Alfred | Method of producing extracellular enzymes, the enzymes produced thereby and compositions containing them; a hybrid plasmid and a dna fragment comprising dna encoding the enzymes; a microorganism harbouring the plasmid; and a method for removing nucleic acids from biological materials |
| AU2589095A (en) | 1994-05-16 | 1995-12-05 | Washington University | Cell membrane fusion composition and method |
| AU6691496A (en) * | 1995-08-01 | 1997-02-26 | Advanced Therapies, Inc. | Enhanced artificial viral envelopes for cellular delivery of therapeutic substances |
| US6013516A (en) | 1995-10-06 | 2000-01-11 | The Salk Institute For Biological Studies | Vector and method of use for nucleic acid delivery to non-dividing cells |
| PT904392E (pt) | 1996-10-17 | 2001-06-29 | Oxford Biomedica Ltd | Vectores retrovirais |
| WO1999013905A1 (en) | 1997-09-18 | 1999-03-25 | The Trustees Of The University Of Pennsylvania | Receptor-binding pocket mutants of influenza a virus hemagglutinin for use in targeted gene delivery |
| GB9720465D0 (en) | 1997-09-25 | 1997-11-26 | Oxford Biomedica Ltd | Dual-virus vectors |
| US5994136A (en) | 1997-12-12 | 1999-11-30 | Cell Genesys, Inc. | Method and means for producing high titer, safe, recombinant lentivirus vectors |
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| FR2777909B1 (fr) | 1998-04-24 | 2002-08-02 | Pasteur Institut | Utilisation de sequences d'adn de structure triplex pour le tranfert de sequences de nucleotides dans des cellules, vecteurs recombinants contenant ces sequences triplex |
| DE69938931D1 (de) * | 1998-09-23 | 2008-07-31 | Inst Virologie Teilrechtsfaehi | Retrovirale partikel, geschützt gegen komplementvermittelte lyse |
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| WO2002088346A2 (en) | 2001-05-01 | 2002-11-07 | National Research Council Of Canada | A system for inducible expression in eukaryotic cells |
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| AU2003258060B2 (en) | 2002-03-27 | 2007-07-12 | Baylor College Of Medicine | Potent oncolytic herpes simplex virus for cancer therapy |
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| WO2005059111A2 (en) | 2003-12-17 | 2005-06-30 | The Trustees Of Columbia University In The City Of New York | DELIVERY OF DNA OR RNA VIA GAP JUNCTIONS FROM HOST CELLS TO TARGET CELLS AND A CELL-BASED DELIVERY SYSTEM FOR ANTISENSE OR SiRNA |
| WO2006027202A1 (en) | 2004-09-06 | 2006-03-16 | Unite De Recherche En Biotherapie Et Oncologie (Rubio) | Generation of multiparent cell hybrids |
| AU2005306801B2 (en) | 2004-11-08 | 2012-05-17 | The Regents Of The University Of Colorado | Structure-based compound design involving riboswitches |
| CA2609142C (en) | 2005-05-27 | 2016-02-09 | Fondazione Centro San Raffaele Del Monte Tabor | Therapeutic gene vectors comprising mirna target sequences |
| WO2007099387A1 (en) | 2006-03-03 | 2007-09-07 | Mymetics Corporation | Virosome-like vesicles comprising gp41-derived antigens |
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| WO2012156839A2 (en) | 2011-05-19 | 2012-11-22 | Ospedale San Raffaele S.R.L. | New generation of splice-less lentiviral vectors for safer gene therapy applications |
| KR20150029756A (ko) * | 2011-06-10 | 2015-03-18 | 블루버드 바이오, 인코포레이티드. | 부신백질이영양증 및 부신척수신경병증을 위한 유전자 요법 벡터 |
| US20160289674A1 (en) | 2012-04-02 | 2016-10-06 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of membrane proteins |
| KR102396026B1 (ko) * | 2014-01-21 | 2022-05-09 | 안자리움 바이오사이언시스 아게 | 하이브리도좀, 이를 포함하는 조성물, 이의 제조 방법 및 이의 용도 |
| GB201412494D0 (en) * | 2014-07-14 | 2014-08-27 | Ospedale San Raffaele And Fond Telethon | Vector production |
| US20180163178A1 (en) * | 2015-05-29 | 2018-06-14 | Robert J. Schneider | Auf1 encoding compositions for muscle cell uptake, satellite cell populations, and satellite cell mediated muscle generation |
| US20170112773A1 (en) | 2015-10-23 | 2017-04-27 | Board Of Regents, The University Of Texas System | Plasma membrane vesicles comprising functional transmembrane proteins |
| WO2017151717A1 (en) * | 2016-03-01 | 2017-09-08 | French Brent A | Compositions and methods for adeno-associated virus mediated gene expression in myofibroblast-like cells |
| EP3235908A1 (en) * | 2016-04-21 | 2017-10-25 | Ecole Normale Superieure De Lyon | Methods for selectively modulating the activity of distinct subtypes of cells |
| WO2017211945A1 (en) * | 2016-06-09 | 2017-12-14 | Alma Mater Studiorum Universita Di Bologna | Herpesvirus with modified glycoprotein h for propagation in a cell |
| CA3030003A1 (en) * | 2016-07-08 | 2018-01-11 | F1 Oncology, Inc. | Methods and compositions for transducing lymphocytes and regulating the activity thereof |
| WO2018022747A1 (en) * | 2016-07-26 | 2018-02-01 | Senti Biosciences, Inc. | Genetic erasers |
| MA45783A (fr) | 2016-07-29 | 2019-06-05 | Juno Therapeutics Inc | Procédés d'évaluation de la présence ou de l'absence d'un virus compétent pour la réplication |
| AU2019215063B2 (en) * | 2018-02-01 | 2025-10-16 | Bioverativ Therapeutics, Inc. | Use of lentiviral vectors expressing Factor VIII |
-
2019
- 2019-05-15 SG SG11202011015QA patent/SG11202011015QA/en unknown
- 2019-05-15 IL IL278665A patent/IL278665B2/en unknown
- 2019-05-15 BR BR112020023015-4A patent/BR112020023015A2/pt unknown
- 2019-05-15 CA CA3099497A patent/CA3099497A1/en active Pending
- 2019-05-15 AU AU2019269593A patent/AU2019269593A1/en active Pending
- 2019-05-15 KR KR1020267005235A patent/KR20260042239A/ko active Pending
- 2019-05-15 US US17/055,077 patent/US20210228627A1/en active Pending
- 2019-05-15 JP JP2020564225A patent/JP7568513B2/ja active Active
- 2019-05-15 MX MX2020012295A patent/MX2020012295A/es unknown
- 2019-05-15 KR KR1020207036111A patent/KR102930875B1/ko active Active
- 2019-05-15 WO PCT/US2019/032488 patent/WO2019222403A2/en not_active Ceased
- 2019-05-15 EP EP19740433.8A patent/EP3793570A2/en active Pending
- 2019-05-15 CN CN201980045045.1A patent/CN112367973A/zh active Pending
-
2020
- 2020-11-13 MX MX2025008552A patent/MX2025008552A/es unknown
-
2024
- 2024-05-20 JP JP2024081800A patent/JP7815327B2/ja active Active
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