JP2021523214A5 - - Google Patents

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Publication number
JP2021523214A5
JP2021523214A5 JP2020564676A JP2020564676A JP2021523214A5 JP 2021523214 A5 JP2021523214 A5 JP 2021523214A5 JP 2020564676 A JP2020564676 A JP 2020564676A JP 2020564676 A JP2020564676 A JP 2020564676A JP 2021523214 A5 JP2021523214 A5 JP 2021523214A5
Authority
JP
Japan
Prior art keywords
composition according
pcsk9
approximately
fusion protein
unit dose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020564676A
Other languages
English (en)
Japanese (ja)
Other versions
JP7515406B2 (ja
JP2021523214A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/032710 external-priority patent/WO2019222529A1/en
Publication of JP2021523214A publication Critical patent/JP2021523214A/ja
Publication of JP2021523214A5 publication Critical patent/JP2021523214A5/ja
Application granted granted Critical
Publication of JP7515406B2 publication Critical patent/JP7515406B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2020564676A 2018-05-16 2019-05-16 Ｐｃｓｋ９結合分子を含む組成物及びその使用方法 Active JP7515406B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862672187P 2018-05-16 2018-05-16
US62/672,187 2018-05-16
PCT/US2019/032710 WO2019222529A1 (en) 2018-05-16 2019-05-16 Compositions comprising pcsk9-binding molecules and methods of use

Publications (3)

Publication Number Publication Date
JP2021523214A JP2021523214A (ja) 2021-09-02
JP2021523214A5 true JP2021523214A5 (https=) 2022-05-20
JP7515406B2 JP7515406B2 (ja) 2024-07-12

Family

ID=68540981

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020564676A Active JP7515406B2 (ja) 2018-05-16 2019-05-16 Ｐｃｓｋ９結合分子を含む組成物及びその使用方法

Country Status (15)

Country Link
US (3) US10738102B2 (https=)
EP (1) EP3793612A4 (https=)
JP (1) JP7515406B2 (https=)
KR (1) KR20210010890A (https=)
CN (2) CN120643704A (https=)
AU (1) AU2019269617B2 (https=)
BR (1) BR112020023344A2 (https=)
CA (1) CA3115341A1 (https=)
EA (1) EA202092778A1 (https=)
IL (1) IL278710B2 (https=)
MX (1) MX2020012214A (https=)
SG (1) SG11202011304QA (https=)
UA (1) UA130399C2 (https=)
WO (1) WO2019222529A1 (https=)
ZA (1) ZA202007107B (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA202092778A1 (ru) * 2018-05-16 2021-05-27 ЛИБ ТЕРАПЬЮТИКС, ЭлЭлСи Композиции, содержащие pcsk9-связывающие молекулы, и способы применения

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101494067B1 (ko) * 2004-03-05 2015-02-16 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 부작용을 최소화하면서 과지질혈증 및 과콜레스테롤혈증과 연관된 질환 또는 질병의 치료 방법
MX2010011499A (es) * 2008-04-23 2010-11-12 Amgen Inc Variantes de proproteina neutralizante de convertasa subtilisina kexina de tipo 9 (pcsk9) y sus usos.
EP2558491B1 (en) * 2010-04-13 2018-07-04 Bristol-Myers Squibb Company Fibronectin based scaffold domain proteins that bind pcsk9
SG192117A1 (en) * 2011-01-28 2013-08-30 Sanofi Sa Human antibodies to pcsk9 for use in methods of treating particular groups of subjects
US9255154B2 (en) * 2012-05-08 2016-02-09 Alderbio Holdings, Llc Anti-PCSK9 antibodies and use thereof
EP2968587A2 (en) * 2013-03-13 2016-01-20 Bristol-Myers Squibb Company Fibronectin based scaffold domains linked to serum albumin or a moiety binding thereto
HK1213194A1 (zh) * 2013-03-14 2016-06-30 Daiichi Sankyo Co., Ltd. 用於新型的结合蛋白质pcsk9
ES2736127T3 (es) * 2014-03-20 2019-12-26 Bristol Myers Squibb Co Dominios de tipo III de fibronectina de unión a seroalbúmina
CA2943228C (en) * 2014-03-20 2023-03-14 Bristol-Myers Squibb Company Stabilized fibronectin based scaffold molecules
AU2016228806B2 (en) 2015-03-12 2020-10-22 Medimmune, Llc Method of purifying albumin-fusion proteins
EA202092778A1 (ru) * 2018-05-16 2021-05-27 ЛИБ ТЕРАПЬЮТИКС, ЭлЭлСи Композиции, содержащие pcsk9-связывающие молекулы, и способы применения
WO2022268214A1 (zh) * 2021-06-25 2022-12-29 甘李药业股份有限公司 Pcsk9抑制剂和glp-1受体激动剂的药物组合

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