SG11202011304QA - Compositions comprising pcsk9-binding molecules and methods of use - Google Patents
Compositions comprising pcsk9-binding molecules and methods of useInfo
- Publication number
- SG11202011304QA SG11202011304QA SG11202011304QA SG11202011304QA SG11202011304QA SG 11202011304Q A SG11202011304Q A SG 11202011304QA SG 11202011304Q A SG11202011304Q A SG 11202011304QA SG 11202011304Q A SG11202011304Q A SG 11202011304QA SG 11202011304Q A SG11202011304Q A SG 11202011304QA
- Authority
- SG
- Singapore
- Prior art keywords
- pcsk9
- compositions
- methods
- binding molecules
- molecules
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/765—Serum albumin, e.g. HSA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2318/00—Antibody mimetics or scaffolds
- C07K2318/20—Antigen-binding scaffold molecules wherein the scaffold is not an immunoglobulin variable region or antibody mimetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862672187P | 2018-05-16 | 2018-05-16 | |
PCT/US2019/032710 WO2019222529A1 (en) | 2018-05-16 | 2019-05-16 | Compositions comprising pcsk9-binding molecules and methods of use |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202011304QA true SG11202011304QA (en) | 2020-12-30 |
Family
ID=68540981
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202011304QA SG11202011304QA (en) | 2018-05-16 | 2019-05-16 | Compositions comprising pcsk9-binding molecules and methods of use |
Country Status (13)
Country | Link |
---|---|
US (3) | US10738102B2 (en) |
EP (1) | EP3793612A4 (en) |
JP (1) | JP2021523214A (en) |
KR (1) | KR20210010890A (en) |
CN (1) | CN112423790A (en) |
AU (1) | AU2019269617A1 (en) |
BR (1) | BR112020023344A2 (en) |
CA (1) | CA3115341A1 (en) |
EA (1) | EA202092778A1 (en) |
MX (1) | MX2020012214A (en) |
SG (1) | SG11202011304QA (en) |
WO (1) | WO2019222529A1 (en) |
ZA (1) | ZA202007107B (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3793612A4 (en) * | 2018-05-16 | 2022-03-02 | LIB Therapeutics, LLC | Compositions comprising pcsk9-binding molecules and methods of use |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8420098B2 (en) * | 2010-04-13 | 2013-04-16 | Bristol-Myers Squibb Company | Fibronectin based scaffold domain proteins that bind to PCSK9 |
US9255154B2 (en) * | 2012-05-08 | 2016-02-09 | Alderbio Holdings, Llc | Anti-PCSK9 antibodies and use thereof |
WO2014165093A2 (en) | 2013-03-13 | 2014-10-09 | Bristol-Myers Squibb Company | Fibronectin based scaffold domains linked to serum albumin or a moiety binding thereto |
CN105246503A (en) * | 2013-03-14 | 2016-01-13 | 第一三共株式会社 | Novel binding proteins for pcsk9 |
EP3647322B1 (en) * | 2014-03-20 | 2021-10-20 | Bristol-Myers Squibb Company | Stabilized fibronectin based scaffold molecules |
CA2943241C (en) * | 2014-03-20 | 2023-09-19 | Bristol-Myers Squibb Company | Serum albumin-binding fibronectin type iii domains |
CN107428817B (en) | 2015-03-12 | 2022-07-12 | 免疫医疗有限责任公司 | Method for purifying albumin fusion proteins |
EP3793612A4 (en) * | 2018-05-16 | 2022-03-02 | LIB Therapeutics, LLC | Compositions comprising pcsk9-binding molecules and methods of use |
-
2019
- 2019-05-16 EP EP19804334.1A patent/EP3793612A4/en active Pending
- 2019-05-16 KR KR1020207035740A patent/KR20210010890A/en unknown
- 2019-05-16 MX MX2020012214A patent/MX2020012214A/en unknown
- 2019-05-16 EA EA202092778A patent/EA202092778A1/en unknown
- 2019-05-16 CN CN201980047552.9A patent/CN112423790A/en active Pending
- 2019-05-16 CA CA3115341A patent/CA3115341A1/en active Pending
- 2019-05-16 WO PCT/US2019/032710 patent/WO2019222529A1/en unknown
- 2019-05-16 JP JP2020564676A patent/JP2021523214A/en active Pending
- 2019-05-16 SG SG11202011304QA patent/SG11202011304QA/en unknown
- 2019-05-16 BR BR112020023344-7A patent/BR112020023344A2/en unknown
- 2019-05-16 AU AU2019269617A patent/AU2019269617A1/en active Pending
- 2019-09-20 US US16/578,102 patent/US10738102B2/en active Active
-
2020
- 2020-07-21 US US16/934,816 patent/US11692021B2/en active Active
- 2020-11-13 ZA ZA2020/07107A patent/ZA202007107B/en unknown
-
2023
- 2023-05-16 US US18/318,343 patent/US20230295270A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
CN112423790A (en) | 2021-02-26 |
AU2019269617A1 (en) | 2020-12-03 |
JP2021523214A (en) | 2021-09-02 |
EA202092778A1 (en) | 2021-05-27 |
US11692021B2 (en) | 2023-07-04 |
AU2019269617A8 (en) | 2020-12-17 |
KR20210010890A (en) | 2021-01-28 |
CA3115341A1 (en) | 2019-11-21 |
EP3793612A1 (en) | 2021-03-24 |
US20230295270A1 (en) | 2023-09-21 |
US10738102B2 (en) | 2020-08-11 |
WO2019222529A1 (en) | 2019-11-21 |
US20210002350A1 (en) | 2021-01-07 |
EP3793612A4 (en) | 2022-03-02 |
BR112020023344A2 (en) | 2021-02-09 |
ZA202007107B (en) | 2022-03-30 |
MX2020012214A (en) | 2021-03-31 |
US20200071386A1 (en) | 2020-03-05 |
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