JP2021521227A - 神経障害性疼痛を処置する方法 - Google Patents

神経障害性疼痛を処置する方法 Download PDF

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Publication number
JP2021521227A
JP2021521227A JP2020556855A JP2020556855A JP2021521227A JP 2021521227 A JP2021521227 A JP 2021521227A JP 2020556855 A JP2020556855 A JP 2020556855A JP 2020556855 A JP2020556855 A JP 2020556855A JP 2021521227 A JP2021521227 A JP 2021521227A
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Japan
Prior art keywords
oxy
fluorophenyl
phenyl
methyl
pharmaceutically acceptable
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JP2020556855A
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Japanese (ja)
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JP2021521227A5 (https=
JPWO2019204136A5 (https=
Inventor
ザオ ユアン
ザオ ユアン
ナイク ヒマーンシュ
ナイク ヒマーンシュ
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Biogen MA Inc
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Biogen MA Inc
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Publication of JP2021521227A publication Critical patent/JP2021521227A/ja
Publication of JP2021521227A5 publication Critical patent/JP2021521227A5/ja
Publication of JPWO2019204136A5 publication Critical patent/JPWO2019204136A5/ja
Withdrawn legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2020556855A 2018-04-16 2019-04-12 神経障害性疼痛を処置する方法 Withdrawn JP2021521227A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862658347P 2018-04-16 2018-04-16
US62/658,347 2018-04-16
PCT/US2019/027158 WO2019204136A1 (en) 2018-04-16 2019-04-12 Methods of treating neuropathic pain

Publications (3)

Publication Number Publication Date
JP2021521227A true JP2021521227A (ja) 2021-08-26
JP2021521227A5 JP2021521227A5 (https=) 2022-04-20
JPWO2019204136A5 JPWO2019204136A5 (https=) 2022-04-20

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ID=68239826

Family Applications (1)

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JP2020556855A Withdrawn JP2021521227A (ja) 2018-04-16 2019-04-12 神経障害性疼痛を処置する方法

Country Status (14)

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US (1) US20210154170A1 (https=)
EP (1) EP3781157A4 (https=)
JP (1) JP2021521227A (https=)
KR (1) KR20210002472A (https=)
CN (1) CN112367990A (https=)
AU (1) AU2019255519A1 (https=)
BR (1) BR112020021101A2 (https=)
CA (1) CA3093401A1 (https=)
EA (1) EA202092482A1 (https=)
IL (1) IL277962A (https=)
MX (1) MX2020010929A (https=)
SG (1) SG11202008681PA (https=)
TW (2) TW202245750A (https=)
WO (1) WO2019204136A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11116737B1 (en) 2020-04-10 2021-09-14 University Of Georgia Research Foundation, Inc. Methods of using probenecid for treatment of coronavirus infections

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009511519A (ja) * 2005-10-10 2009-03-19 グラクソ グループ リミテッド ナトリウムチャネルモジュレーターとしてのプロリンアミド誘導体
WO2015185924A1 (en) * 2014-06-03 2015-12-10 Convergence Pharmaceuticals Limited Diagnostic method
WO2016051194A1 (en) * 2014-10-03 2016-04-07 Convergence Pharmaceuticals Limited Erythromelalgia treatment

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2264182A1 (en) * 1996-08-23 1998-02-26 Algos Pharmaceutical Corporation Anticonvulsant containing composition for treating neuropathic pain
JP2019537601A (ja) * 2016-11-02 2019-12-26 バイオジェン・エムエイ・インコーポレイテッドＢｉｏｇｅｎ ＭＡ Ｉｎｃ． 新規投薬レジメン

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009511519A (ja) * 2005-10-10 2009-03-19 グラクソ グループ リミテッド ナトリウムチャネルモジュレーターとしてのプロリンアミド誘導体
WO2015185924A1 (en) * 2014-06-03 2015-12-10 Convergence Pharmaceuticals Limited Diagnostic method
WO2016051194A1 (en) * 2014-10-03 2016-04-07 Convergence Pharmaceuticals Limited Erythromelalgia treatment

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT, vol. Vol.6, Supplement 1, JPN6023019168, 2017, pages 49 - 50, ISSN: 0005058710 *
J PAIN RELIEF, vol. 4, no. 3, JPN6023019162, 2015, pages 36, ISSN: 0005058712 *
JOURNAL OF MEDICINE AND THERAPEUTICS, vol. 1, no. 1, JPN6023019165, 2017, pages 1 - 3, ISSN: 0005058715 *
PHARMACOLOGY & THERAPEUTICS, vol. 106, JPN6023019167, 2005, pages 97 - 132, ISSN: 0005058718 *
THE JOURNAL OF PAIN, vol. 16, no. 4, JPN6023019163, 2015, pages 72 - 386, ISSN: 0005058713 *
THE JOURNAL OF PAIN, vol. 16, no. 4, JPN6023019164, 2015, pages 72 - 387, ISSN: 0005058714 *
TRIALS, vol. 14, JPN6023019160, 2013, pages 402, ISSN: 0005058711 *
日薬理誌（FOLIA PHARMACOL. JPN.）, vol. 134, JPN6023019169, 2009, pages 334 - 337, ISSN: 0005058716 *
薬剤学, vol. 74, no. 6, JPN6023019166, 2014, pages 406 - 413, ISSN: 0005058717 *

Also Published As

Publication number Publication date
MX2020010929A (es) 2020-11-06
TWI803619B (zh) 2023-06-01
US20210154170A1 (en) 2021-05-27
CA3093401A1 (en) 2019-10-24
AU2019255519A1 (en) 2020-10-01
IL277962A (en) 2020-11-30
SG11202008681PA (en) 2020-10-29
TW202245750A (zh) 2022-12-01
EA202092482A1 (ru) 2021-03-30
BR112020021101A2 (pt) 2021-02-23
CN112367990A (zh) 2021-02-12
EP3781157A1 (en) 2021-02-24
KR20210002472A (ko) 2021-01-08
WO2019204136A1 (en) 2019-10-24
EP3781157A4 (en) 2022-01-26
TW201946619A (zh) 2019-12-16

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