JP2021520853A5 - - Google Patents
Info
- Publication number
- JP2021520853A5 JP2021520853A5 JP2021505621A JP2021505621A JP2021520853A5 JP 2021520853 A5 JP2021520853 A5 JP 2021520853A5 JP 2021505621 A JP2021505621 A JP 2021505621A JP 2021505621 A JP2021505621 A JP 2021505621A JP 2021520853 A5 JP2021520853 A5 JP 2021520853A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- composition according
- nucleic acid
- receptor
- domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024084707A JP7855638B2 (ja) | 2018-04-12 | 2024-05-24 | ウイルスベクター及びパッケージング細胞株 |
| JP2026038268A JP2026088200A (ja) | 2018-04-12 | 2026-03-10 | ウイルスベクター及びパッケージング細胞株 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862656823P | 2018-04-12 | 2018-04-12 | |
| US62/656,823 | 2018-04-12 | ||
| PCT/US2019/026923 WO2019200056A2 (en) | 2018-04-12 | 2019-04-11 | Viral vectors and packaging cell lines |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024084707A Division JP7855638B2 (ja) | 2018-04-12 | 2024-05-24 | ウイルスベクター及びパッケージング細胞株 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021520853A JP2021520853A (ja) | 2021-08-26 |
| JP2021520853A5 true JP2021520853A5 (enExample) | 2022-04-18 |
| JP7721436B2 JP7721436B2 (ja) | 2025-08-12 |
Family
ID=66287035
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021505621A Active JP7721436B2 (ja) | 2018-04-12 | 2019-04-11 | ウイルスベクター及びパッケージング細胞株 |
| JP2024084707A Active JP7855638B2 (ja) | 2018-04-12 | 2024-05-24 | ウイルスベクター及びパッケージング細胞株 |
| JP2026038268A Pending JP2026088200A (ja) | 2018-04-12 | 2026-03-10 | ウイルスベクター及びパッケージング細胞株 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024084707A Active JP7855638B2 (ja) | 2018-04-12 | 2024-05-24 | ウイルスベクター及びパッケージング細胞株 |
| JP2026038268A Pending JP2026088200A (ja) | 2018-04-12 | 2026-03-10 | ウイルスベクター及びパッケージング細胞株 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US12215337B2 (enExample) |
| EP (1) | EP3775231A2 (enExample) |
| JP (3) | JP7721436B2 (enExample) |
| CN (1) | CN112262214A (enExample) |
| AU (2) | AU2019252285B2 (enExample) |
| BR (1) | BR112020020887A2 (enExample) |
| CA (1) | CA3096458A1 (enExample) |
| IL (2) | IL277936B1 (enExample) |
| SG (1) | SG11202009975TA (enExample) |
| WO (1) | WO2019200056A2 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2934532B1 (en) | 2012-12-20 | 2019-10-23 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| US11111505B2 (en) | 2016-03-19 | 2021-09-07 | Exuma Biotech, Corp. | Methods and compositions for transducing lymphocytes and regulating the activity thereof |
| US11325948B2 (en) | 2016-03-19 | 2022-05-10 | Exuma Biotech Corp. | Methods and compositions for genetically modifying lymphocytes to express polypeptides comprising the intracellular domain of MPL |
| US12590321B2 (en) | 2016-03-19 | 2026-03-31 | Exuma Biotech Corp. | Methods and compositions for genetically modifying and expanding lymphocytes and regulating the activity thereof |
| CA3019835A1 (en) | 2016-04-08 | 2017-10-12 | Purdue Research Foundation | Methods and compositions for car t cell therapy |
| CN110582288B (zh) | 2017-02-28 | 2024-09-20 | 恩多塞特公司 | 用于car t细胞疗法的组合物和方法 |
| WO2019144095A1 (en) | 2018-01-22 | 2019-07-25 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Methods of use for car t cells |
| JP7568224B2 (ja) | 2018-02-23 | 2024-10-16 | エンドサイト・インコーポレイテッド | Ｃａｒ ｔ細胞療法のための配列決定法 |
| SG11202009975TA (en) | 2018-04-12 | 2020-11-27 | Umoja Biopharma Inc | Viral vectors and packaging cell lines |
| EP3884058A1 (en) | 2018-11-21 | 2021-09-29 | Umoja Biopharma, Inc. | Multicistronic vector for surface engineering lentiviral particles |
| EP4045663A2 (en) * | 2019-10-16 | 2022-08-24 | Umoja Biopharma, Inc. | Retroviral vector for univeral receptor therapy |
| WO2021154839A1 (en) | 2020-01-30 | 2021-08-05 | Umoja Biopharma, Inc. | Bispecific transduction enhancer |
| US20230201440A1 (en) * | 2020-05-08 | 2023-06-29 | Innovative Cellular Therapeutics Holdings, Ltd. | System and method for gene and/or cellular therapy |
| KR20230156687A (ko) * | 2020-11-20 | 2023-11-14 | 우모자 바이오파마 인코포레이티드 | 다수 폴리뉴클레오티드들의 전달을 위한 벡터 시스템 및 그의 용도 |
| WO2022164935A1 (en) | 2021-01-27 | 2022-08-04 | Umoja Biopharma, Inc. | Lentivirus for generating cells expressing anti-cd19 chimeric antigen receptor |
| KR20250008769A (ko) * | 2022-05-06 | 2025-01-15 | 우모자 바이오파마 인코포레이티드 | 표면 자극 분자를 가진 바이러스 입자 |
| CN120457212A (zh) * | 2022-11-04 | 2025-08-08 | 优莫佳生物制药股份有限公司 | 展示融合分子的慢病毒颗粒及其用途 |
| US20260176651A1 (en) * | 2022-11-04 | 2026-06-25 | Umoja Biopharma, Inc. | Particles displaying adhesion-molecule fusions |
| WO2024215987A1 (en) | 2023-04-14 | 2024-10-17 | Sotio Biotech Inc. | IMMUNE CELLS FOR TREATING CANCER IN COMBINATION WITH IL-15/IL-15Rα CONJUGATES |
| EP4694916A1 (en) | 2023-04-14 | 2026-02-18 | SOTIO Biotech Inc. | Engineered immune cells for treating cancer in combination with il-2/il-15 receptor ?? agonists |
| EP4702034A1 (en) | 2023-04-27 | 2026-03-04 | Miltenyi Biotec B.V. & Co. KG | Pseudotyped retroviral vector particle with anti-cd3 display |
| WO2024238153A1 (en) * | 2023-05-15 | 2024-11-21 | Umoja Biopharma, Inc. | Lentiviral delivery of anti-cd20 chimeric antigen receptors |
| WO2024238769A2 (en) * | 2023-05-16 | 2024-11-21 | The Regents Of The University Of California | Inhibitory chimeric antigen receptors that reduce car-t cell "on-target, off-tumor" toxicity |
| WO2025078492A1 (en) | 2023-10-13 | 2025-04-17 | Miltenyi Biotec B.V. & Co. KG | Cd3-targeted nipah-pseudotyped lentiviral vector particles |
| WO2025162379A1 (zh) * | 2024-02-01 | 2025-08-07 | 深圳市济因生物科技有限公司 | 一种多肽及包含所述多肽基因的病毒载体 |
| WO2026051968A1 (zh) * | 2024-09-04 | 2026-03-12 | 深圳易慕峰生物科技股份有限公司 | 一种新型病毒颗粒及其应用 |
| WO2026149447A1 (zh) * | 2025-01-07 | 2026-07-16 | 深圳市济因生物科技有限公司 | 一种颗粒及其应用 |
Family Cites Families (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6013516A (en) | 1995-10-06 | 2000-01-11 | The Salk Institute For Biological Studies | Vector and method of use for nucleic acid delivery to non-dividing cells |
| US5739018A (en) | 1996-08-07 | 1998-04-14 | The Regents Of The University Of California | Packaging cell lines for pseudotyped retroviral vectors |
| US6207455B1 (en) | 1997-05-01 | 2001-03-27 | Lung-Ji Chang | Lentiviral vectors |
| CN1247788C (zh) | 1997-05-13 | 2006-03-29 | 北卡罗来纳-查佩尔山大学 | 基于慢病毒的基因转移载体 |
| US6136597A (en) | 1997-09-18 | 2000-10-24 | The Salk Institute For Biological Studies | RNA export element |
| US5994136A (en) | 1997-12-12 | 1999-11-30 | Cell Genesys, Inc. | Method and means for producing high titer, safe, recombinant lentivirus vectors |
| AU3893000A (en) | 1999-03-16 | 2000-10-04 | Dana-Farber Cancer Institute, Inc. | Lentiviral vector system for high quantity screening |
| HK1050210B (en) | 1999-10-12 | 2007-08-24 | Institut Pasteur | Lentiviral triplex dna, and vectors and recombinant cells containing lentiviral triplex dna |
| US7939059B2 (en) | 2001-12-10 | 2011-05-10 | California Institute Of Technology | Method for the generation of antigen-specific lymphocytes |
| US7135339B2 (en) | 2003-11-20 | 2006-11-14 | University Of Iowa Research Foundation | Methods for producing and using in vivo pseudotyped retroviruses using envelope glycoproteins from lymphocytic choriomeningitis virus (LCMV) |
| CN101072880A (zh) | 2004-07-01 | 2007-11-14 | VIRxSYS股份有限公司 | 载体包装细胞系 |
| JP2006085744A (ja) | 2004-09-14 | 2006-03-30 | Matsushita Electric Ind Co Ltd | 磁気記録再生装置及びそのテープスレッディング方法 |
| WO2007095201A2 (en) | 2006-02-15 | 2007-08-23 | The Regents Of The University Of California | Pseudotyped retroviral vectors and methods of use thereof |
| US20090304657A1 (en) | 2006-05-03 | 2009-12-10 | The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services | Chimeric t cell receptors and related materials and methods of use |
| US8293685B2 (en) | 2007-07-26 | 2012-10-23 | The Regents Of The University Of California | Methods for enhancing bacterial cell display of proteins and peptides |
| US9273283B2 (en) | 2009-10-29 | 2016-03-01 | The Trustees Of Dartmouth College | Method of producing T cell receptor-deficient T cells expressing a chimeric receptor |
| GB0920775D0 (en) | 2009-11-26 | 2010-01-13 | King S College | Cells |
| WO2013188693A1 (en) | 2012-06-15 | 2013-12-19 | Imaginab, Inc. | Antigen binding constructs to cd3 |
| EP2934532B1 (en) | 2012-12-20 | 2019-10-23 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| EP3027204B1 (en) | 2013-07-29 | 2022-01-05 | 2seventy bio, Inc. | Multipartite signaling proteins and uses thereof |
| WO2015090229A1 (en) * | 2013-12-20 | 2015-06-25 | Novartis Ag | Regulatable chimeric antigen receptor |
| CN122399016A (zh) | 2014-03-15 | 2026-07-17 | 诺华股份有限公司 | 使用嵌合抗原受体治疗癌症 |
| WO2015142661A1 (en) | 2014-03-15 | 2015-09-24 | Novartis Ag | Regulatable chimeric antigen receptor |
| EP3166968B1 (en) | 2014-05-02 | 2021-09-22 | The Trustees of the University of Pennsylvania | Compositions and methods of chimeric autoantibody receptor t cells |
| GB201412494D0 (en) * | 2014-07-14 | 2014-08-27 | Ospedale San Raffaele And Fond Telethon | Vector production |
| CA2956385A1 (en) | 2014-07-25 | 2016-01-28 | Theravectys | Lentiviral vectors for regulated expression of a chimeric antigen receptor molecule |
| TWI751102B (zh) | 2014-08-28 | 2022-01-01 | 美商奇諾治療有限公司 | 對ｃｄ１９具專一性之抗體及嵌合抗原受體 |
| WO2016118775A1 (en) | 2015-01-21 | 2016-07-28 | Fred Hutchinson Cancer Research Center | Cocal envelope pseudotyped retroviral vector producer cells |
| CA2977106A1 (en) | 2015-02-27 | 2016-09-01 | Icell Gene Therapeutics Llc | Chimeric antigen receptors (cars) targeting hematologic malignancies, compositions and methods of use thereof |
| GB201503500D0 (en) | 2015-03-02 | 2015-04-15 | Ucl Business Plc | Cell |
| WO2016147182A1 (en) * | 2015-03-16 | 2016-09-22 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Isolated peptides derived from the b7 ligand dimer interface and uses thereof |
| US10829735B2 (en) * | 2015-07-21 | 2020-11-10 | The Trustees Of The University Of Pennsylvania | Methods for improving the efficacy and expansion of immune cells |
| GB201514875D0 (en) | 2015-08-20 | 2015-10-07 | Autolus Ltd | Receptor |
| WO2019055946A1 (en) | 2017-09-18 | 2019-03-21 | F1 Oncology, Inc. | METHODS AND COMPOSITIONS FOR THE GENETIC MODIFICATION AND EXPANSION OF LYMPHOCYTES AND THE REGULATION OF THE ACTIVITY THEREOF |
| CN108884460B (zh) * | 2016-03-19 | 2023-04-28 | 埃克苏马生物技术公司 | 淋巴细胞转导及其扩增调节的方法与组合物 |
| CA3019835A1 (en) | 2016-04-08 | 2017-10-12 | Purdue Research Foundation | Methods and compositions for car t cell therapy |
| US12202856B2 (en) * | 2016-05-19 | 2025-01-21 | The General Hospital Corporation | Tethered interleukin-2 to its receptor IL-2RBETA, a platform to enhance natural killer and regulatory T cell activity |
| KR20190054101A (ko) | 2016-09-14 | 2019-05-21 | 위니베르시트카솔리끄드루뱅 | 변형된 vsv-g 및 이의 백신 |
| CA3045667A1 (en) | 2016-12-13 | 2018-06-21 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Methods of exogenous drug activation of chemical-induced signaling complexes expressed in engineered cells in vitro and in vivo |
| WO2018132508A1 (en) | 2017-01-10 | 2018-07-19 | The General Hospital Corporation | Methods and compositions relating to ex vivo culture and modulation of t cells |
| AU2018219226B2 (en) | 2017-02-07 | 2024-12-19 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents |
| ES3024357T3 (en) | 2017-02-17 | 2025-06-04 | Purdue Research Foundation | Targeted ligand-payload based drug delivery for cell therapy |
| CN110582288B (zh) | 2017-02-28 | 2024-09-20 | 恩多塞特公司 | 用于car t细胞疗法的组合物和方法 |
| KR20200097297A (ko) | 2017-12-07 | 2020-08-18 | 더마반트 사이언시즈 게엠베하 | Pde-4 억제제의 국소 연고 제형 및 피부 병태 치료에서의 이의 용도 |
| WO2019144095A1 (en) | 2018-01-22 | 2019-07-25 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Methods of use for car t cells |
| AU2019218729B2 (en) | 2018-02-06 | 2025-12-04 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Fluorescein-specific CARs exhibiting optimal T cell function against FL-PLE labelled tumors |
| ES3068176T3 (en) | 2018-02-12 | 2026-05-28 | Massachusetts Gen Hospital | Chimeric antigen receptor t cells targeting the tumor microenvironment |
| SG11202009975TA (en) | 2018-04-12 | 2020-11-27 | Umoja Biopharma Inc | Viral vectors and packaging cell lines |
| KR20210074274A (ko) | 2018-08-06 | 2021-06-21 | 시애틀 칠드런즈 호스피탈 디/비/에이 시애틀 칠드런즈 리서치 인스티튜트 | 합텐 표지된 세포로의 키메라 항원 수용체 t 세포의 자극을 위한 방법 및 조성물 |
| AU2019317278B2 (en) | 2018-08-07 | 2025-05-22 | Purdue Research Foundation | Rejuvenation of CAR T cell |
| EP3884058A1 (en) | 2018-11-21 | 2021-09-29 | Umoja Biopharma, Inc. | Multicistronic vector for surface engineering lentiviral particles |
| KR20210110811A (ko) | 2018-11-30 | 2021-09-09 | 주노 쎄러퓨티크스 인코퍼레이티드 | 입양 세포 요법에서 ｂ 세포 악성 종양의 투약 및 치료 방법 |
| EP4045663A2 (en) | 2019-10-16 | 2022-08-24 | Umoja Biopharma, Inc. | Retroviral vector for univeral receptor therapy |
| US12540336B2 (en) | 2020-05-27 | 2026-02-03 | The Medical College Of Wisconsin, Inc. | Lentiviral vector transfer plasmid and methods of use |
| US11517814B2 (en) | 2020-09-03 | 2022-12-06 | Alan Chalmers | Flavour system |
| KR20230156687A (ko) | 2020-11-20 | 2023-11-14 | 우모자 바이오파마 인코포레이티드 | 다수 폴리뉴클레오티드들의 전달을 위한 벡터 시스템 및 그의 용도 |
| WO2022164935A1 (en) | 2021-01-27 | 2022-08-04 | Umoja Biopharma, Inc. | Lentivirus for generating cells expressing anti-cd19 chimeric antigen receptor |
| KR20250008769A (ko) | 2022-05-06 | 2025-01-15 | 우모자 바이오파마 인코포레이티드 | 표면 자극 분자를 가진 바이러스 입자 |
-
2019
- 2019-04-11 SG SG11202009975TA patent/SG11202009975TA/en unknown
- 2019-04-11 AU AU2019252285A patent/AU2019252285B2/en active Active
- 2019-04-11 EP EP19719740.3A patent/EP3775231A2/en active Pending
- 2019-04-11 IL IL277936A patent/IL277936B1/en unknown
- 2019-04-11 CA CA3096458A patent/CA3096458A1/en active Pending
- 2019-04-11 WO PCT/US2019/026923 patent/WO2019200056A2/en not_active Ceased
- 2019-04-11 CN CN201980037729.7A patent/CN112262214A/zh active Pending
- 2019-04-11 IL IL327388A patent/IL327388A/en unknown
- 2019-04-11 BR BR112020020887-6A patent/BR112020020887A2/pt unknown
- 2019-04-11 JP JP2021505621A patent/JP7721436B2/ja active Active
- 2019-04-11 US US17/046,701 patent/US12215337B2/en active Active
-
2024
- 2024-05-24 JP JP2024084707A patent/JP7855638B2/ja active Active
- 2024-12-20 US US18/991,101 patent/US20250122532A1/en active Pending
- 2024-12-20 US US18/991,176 patent/US20250122533A1/en active Pending
-
2025
- 2025-09-25 AU AU2025237995A patent/AU2025237995A1/en active Pending
-
2026
- 2026-03-10 JP JP2026038268A patent/JP2026088200A/ja active Pending
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