JP2021520196A5 - - Google Patents
Info
- Publication number
- JP2021520196A5 JP2021520196A5 JP2020554102A JP2020554102A JP2021520196A5 JP 2021520196 A5 JP2021520196 A5 JP 2021520196A5 JP 2020554102 A JP2020554102 A JP 2020554102A JP 2020554102 A JP2020554102 A JP 2020554102A JP 2021520196 A5 JP2021520196 A5 JP 2021520196A5
- Authority
- JP
- Japan
- Prior art keywords
- adeno
- associated virus
- avv
- muscular dystrophy
- vector
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862651772P | 2018-04-03 | 2018-04-03 | |
| US62/651,772 | 2018-04-03 | ||
| PCT/US2019/025496 WO2019195362A1 (en) | 2018-04-03 | 2019-04-03 | Hinges 1 and/or 4 modified dystrophins for dystrophinopathy therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021520196A JP2021520196A (ja) | 2021-08-19 |
| JP2021520196A5 true JP2021520196A5 (https=) | 2022-04-05 |
Family
ID=68101401
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020554102A Pending JP2021520196A (ja) | 2018-04-03 | 2019-04-03 | ジストロフィン異常症（ｄｙｓｔｒｏｐｈｉｎｏｐａｔｈｙ）治療のためのヒンジ１および／または４の改変ジストロフィン |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20210139550A1 (https=) |
| EP (1) | EP3773605A4 (https=) |
| JP (1) | JP2021520196A (https=) |
| CN (1) | CN111971050A (https=) |
| WO (1) | WO2019195362A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102877920B1 (ko) | 2015-11-16 | 2025-10-30 | 더 리서치 인스티튜트 앳 네이션와이드 칠드런스 하스피탈 | 티틴-기반 근증 및 다른 티틴성병증의 치료를 위한 물질 및 방법 |
| EP3596112A2 (en) | 2017-03-17 | 2020-01-22 | Newcastle University | Adeno-associated virus vector delivery of a fragment of micro-dystrophin to treat muscular dystrophy |
| AR114350A1 (es) | 2018-01-31 | 2020-08-26 | Res Institute At Nationwide ChildrenS Hospital | Terapia genética para la distrofia muscular de cinturas del tipo 2c |
| MY208145A (en) | 2018-06-18 | 2025-04-18 | Res Inst Nationwide Childrens Hospital | Adeno-associated virus vector delivery of muscle specific micro-dystrophin to treat muscular dystrophy |
| KR20210028162A (ko) | 2018-06-29 | 2021-03-11 | 더 리서치 인스티튜트 앳 네이션와이드 칠드런스 하스피탈 | 지대근 이영양증 2a형을 치료하기 위한 재조합 아데노 연관 바이러스 생성물 및 방법 |
| AU2020229340A1 (en) | 2019-02-26 | 2021-09-16 | Research Institute At Nationwide Children's Hospital | Adeno-associated virus vector delivery of B-sarcoglycan and the treatment of muscular dystrophy |
| RS65421B1 (sr) | 2019-08-21 | 2024-05-31 | Res Inst Nationwide Childrens Hospital | Isporuka adeno-asociranog virusnog vektora alfa-sarkoglikana i lečenje mišićne distrofije |
| IL297753A (en) * | 2020-04-29 | 2022-12-01 | Bristol Myers Squibb Co | Minimized dystrophins with spectrin fusion domains and uses thereof |
| IL299094A (en) | 2020-06-15 | 2023-02-01 | Res Inst Nationwide Childrens Hospital | Administration of an adeno-associated virus vector for muscular dystrophies |
| WO2022029543A1 (en) * | 2020-08-06 | 2022-02-10 | Intas Pharmaceuticals Ltd. | Adeno-associated virus vector delivery of micro-dystrophin to treat muscular dystrophy |
| EP4108263A3 (en) | 2021-06-02 | 2023-03-22 | Research Institute at Nationwide Children's Hospital | Recombinant adeno-associated virus products and methods for treating limb girdle muscular dystrophy 2a |
| EP4219726A1 (en) | 2021-10-15 | 2023-08-02 | Research Institute at Nationwide Children's Hospital | Self-complementary adeno-associated virus vector and its use in treatment of muscular dystrophy |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7771993B2 (en) * | 2004-01-23 | 2010-08-10 | The Trustees Of The University Of Pennsylvania | Microutrophin and uses thereof |
| US9624282B2 (en) * | 2012-11-26 | 2017-04-18 | The Curators Of The University Of Missouri | Microdystrophin peptides and methods for treating muscular dystrophy using the same |
| WO2017223128A1 (en) * | 2016-06-21 | 2017-12-28 | The Curators Of The University Of Missouri | Modified dystrophin proteins |
-
2019
- 2019-04-03 US US17/045,266 patent/US20210139550A1/en not_active Abandoned
- 2019-04-03 EP EP19782410.5A patent/EP3773605A4/en not_active Withdrawn
- 2019-04-03 WO PCT/US2019/025496 patent/WO2019195362A1/en not_active Ceased
- 2019-04-03 JP JP2020554102A patent/JP2021520196A/ja active Pending
- 2019-04-03 CN CN201980022798.0A patent/CN111971050A/zh active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2021520196A5 (https=) | ||
| JP2024054426A5 (https=) | ||
| JP2023002555A5 (https=) | ||
| Zengel et al. | Structural and cellular biology of adeno-associated virus attachment and entry | |
| MX2020008932A (es) | Novedosos vectores de virus adenoasociado (aav), vectores de aav que tienen una desamidacion reducida de la capside y usos de estos. | |
| JP2021519791A5 (https=) | ||
| RU2019100525A (ru) | Векторная система на основе аденоассоциированного вируса | |
| PH12020550094A1 (en) | Adeno-associated virus variant capsids and methods of use thereof | |
| JP2019513393A5 (https=) | ||
| JP2021513866A5 (https=) | ||
| JP2008509695A5 (ja) | 欠失可能なドメインタンパク質をコードする遺伝子におけるエクソンスキッピングのためのアデノ随伴ウイルスベクター | |
| JP2018503374A5 (https=) | ||
| JP2019506445A5 (https=) | ||
| JP2010516252A5 (https=) | ||
| JP2019522461A5 (https=) | ||
| JP2017512466A5 (https=) | ||
| Gilbert et al. | Dystrophin expression in muscle following gene transfer with a fully deleted (" gutted") adenovirus is markedly improved by trans-acting adenoviral gene products | |
| JP2012521750A5 (https=) | ||
| JP7853958B2 (ja) | 組み換えａａｖの作製方法 | |
| JP2017529395A5 (https=) | ||
| JP2022551739A5 (https=) | ||
| JP2021534796A5 (https=) | ||
| JP2024119830A5 (https=) | ||
| JP2022501055A5 (https=) | ||
| JP2018533976A5 (https=) |