JP2021519285A5 - - Google Patents

Info

Publication number
JP2021519285A5
JP2021519285A5 JP2020551481A JP2020551481A JP2021519285A5 JP 2021519285 A5 JP2021519285 A5 JP 2021519285A5 JP 2020551481 A JP2020551481 A JP 2020551481A JP 2020551481 A JP2020551481 A JP 2020551481A JP 2021519285 A5 JP2021519285 A5 JP 2021519285A5
Authority
JP
Japan
Prior art keywords
cancer
combination
pharmaceuticals
fluorophenyl
fluoro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020551481A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021519285A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2019/052601 external-priority patent/WO2019186488A1/en
Publication of JP2021519285A publication Critical patent/JP2021519285A/ja
Publication of JP2021519285A5 publication Critical patent/JP2021519285A5/ja
Pending legal-status Critical Current

Links

JP2020551481A 2018-03-30 2019-03-29 ダブラフェニブ、トラメチニブ及びerk阻害剤を含む医薬品の三重の組合せ Pending JP2021519285A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862650744P 2018-03-30 2018-03-30
US62/650,744 2018-03-30
PCT/IB2019/052601 WO2019186488A1 (en) 2018-03-30 2019-03-29 A triple pharmaceutical combination comprising dabrafenib, trametinib and an erk inhibitor

Publications (2)

Publication Number Publication Date
JP2021519285A JP2021519285A (ja) 2021-08-10
JP2021519285A5 true JP2021519285A5 (enExample) 2022-04-06

Family

ID=66397350

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020551481A Pending JP2021519285A (ja) 2018-03-30 2019-03-29 ダブラフェニブ、トラメチニブ及びerk阻害剤を含む医薬品の三重の組合せ

Country Status (13)

Country Link
US (1) US20210121460A1 (enExample)
EP (1) EP3773586A1 (enExample)
JP (1) JP2021519285A (enExample)
KR (1) KR20200138303A (enExample)
CN (1) CN111936141A (enExample)
AU (1) AU2019246719B2 (enExample)
BR (1) BR112020019577A2 (enExample)
CA (1) CA3094780A1 (enExample)
CL (1) CL2020002505A1 (enExample)
IL (1) IL277380A (enExample)
MX (1) MX2020010231A (enExample)
RU (1) RU2020135055A (enExample)
WO (1) WO2019186488A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230090389A1 (en) * 2020-02-28 2023-03-23 Novartis Ag A triple pharmaceutical combination comprising dabrafenib, an erk inhibitor and a shp2 inhibitor
IL295626A (en) * 2020-02-28 2022-10-01 Novartis Ag A triple pharmaceutical combination comprising dabrafenib, an erk inhibitor and a raf inhibitor
KR20240055721A (ko) * 2021-06-24 2024-04-29 아사나 바이오사이언시스 엘엘씨 Erk1/2 억제제 조합 요법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100883289B1 (ko) 2004-06-11 2009-02-11 니뽄 다바코 산교 가부시키가이샤 암 치료용5-아미노-2,4,7-트리옥소-3,4,7,8-테트라히드로-2h-피리도[2,3-d]피리미딘 유도체 및 관련 화합물
UA103319C2 (en) 2008-05-06 2013-10-10 Глаксосмитклайн Ллк Thiazole- and oxazole-benzene sulfonamide compounds
DK3063143T3 (en) * 2013-11-01 2018-08-20 Novartis Ag Amino heteroaryl benzamides as kinase inhibitors
CA2991805A1 (en) * 2015-07-10 2017-01-19 Genmab A/S Axl-specific antibody-drug conjugates for cancer treatment
CN109715163B (zh) * 2016-09-19 2022-11-22 诺华股份有限公司 包含raf抑制剂和erk抑制剂的治疗组合

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