JP2021519083A5 - - Google Patents
Info
- Publication number
- JP2021519083A5 JP2021519083A5 JP2020551860A JP2020551860A JP2021519083A5 JP 2021519083 A5 JP2021519083 A5 JP 2021519083A5 JP 2020551860 A JP2020551860 A JP 2020551860A JP 2020551860 A JP2020551860 A JP 2020551860A JP 2021519083 A5 JP2021519083 A5 JP 2021519083A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- polypeptide
- lysin
- component
- sequence
- Prior art date
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862650235P | 2018-03-29 | 2018-03-29 | |
| US62/650,235 | 2018-03-29 | ||
| US201862721969P | 2018-08-23 | 2018-08-23 | |
| US62/721,969 | 2018-08-23 | ||
| US201862722793P | 2018-08-24 | 2018-08-24 | |
| US62/722,793 | 2018-08-24 | ||
| PCT/US2019/024912 WO2019191633A2 (en) | 2018-03-29 | 2019-03-29 | Lysin-antimicrobial peptide (amp) polypeptide constructs, lysins, isolated polynucleotides encoding same and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021519083A JP2021519083A (ja) | 2021-08-10 |
| JP2021519083A5 true JP2021519083A5 (https=) | 2022-04-04 |
| JPWO2019191633A5 JPWO2019191633A5 (https=) | 2022-04-04 |
Family
ID=68060804
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020551860A Pending JP2021519083A (ja) | 2018-03-29 | 2019-03-29 | 溶解素−抗微生物ペプチド（ａｍｐ）ポリペプチドコンストラクト、溶解素、それをコードする単離ポリヌクレオチド及びその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US11773140B2 (https=) |
| EP (1) | EP3775192A4 (https=) |
| JP (1) | JP2021519083A (https=) |
| KR (1) | KR20200136980A (https=) |
| CN (1) | CN112368376A (https=) |
| AU (1) | AU2019245369A1 (https=) |
| BR (1) | BR112020019484A2 (https=) |
| CA (1) | CA3095484A1 (https=) |
| IL (1) | IL277119B2 (https=) |
| MX (1) | MX2020010075A (https=) |
| WO (1) | WO2019191633A2 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015200783A2 (en) * | 2014-06-26 | 2015-12-30 | The Rockefeller University | Acinetobacter lysins |
| WO2019118632A1 (en) | 2017-12-12 | 2019-06-20 | Contrafect Corporation | Identification of lysins and derivatives thereof with bacterial activity against pseudomonas aeruginosa |
| WO2019191633A2 (en) | 2018-03-29 | 2019-10-03 | Contrafect Corporation | Lysin-antimicrobial peptide (amp) polypeptide constructs, lysins, isolated polynucleotides encoding same and uses thereof |
| US10988520B2 (en) * | 2018-03-29 | 2021-04-27 | Contrafect Corporation | Lysin-antimicrobial peptide (AMP) polypeptide constructs, lysins, isolated polynucleotides encoding same and uses thereof |
| US20210330738A1 (en) * | 2018-03-29 | 2021-10-28 | Contrafect Corporation | Antimicrobial, bacteriophage-derived polypeptides and their use against gram-negative bacteria |
| EP3840771A4 (en) * | 2018-08-23 | 2023-04-19 | Contrafect Corporation | Lysin-antimicrobial peptide (amp) polypeptide constructs, lysins, isolated polynucleotides encoding same and uses thereof |
| CN114040773A (zh) * | 2019-04-05 | 2022-02-11 | 康特拉费克特公司 | 在存在人血清的情况下对铜绿假单胞菌具有杀菌活性的溶素及其衍生物 |
| KR20220029746A (ko) * | 2019-07-05 | 2022-03-08 | 콘트라펙트 코포레이션 | 항미생물성 박테리오파지 유도된 폴리펩타이드 및 이의 그람 음성 및 항산성 세균에 대한 사용 |
| EP4058468A4 (en) * | 2019-11-14 | 2024-04-10 | Contrafect Corporation | POLYPEPTIDE CONSTRUCTIONS OF ANTIMICROBIAL PEPTIDE LYSINE (AMP), LYSINES, ISOLATED POLYNUCLEOTIDES ENCODING THEREFOR AND USES THEREOF |
| WO2021211303A1 (en) * | 2020-04-14 | 2021-10-21 | Contrafect Corporation | Antiviral, bacteriophage-derived polypeptides and their use against viruses |
| US20210324359A1 (en) * | 2020-04-17 | 2021-10-21 | Contrafect Corporation | Use of gram-negative lysin-antimicrobial peptide (amp) polypeptide constructs in treating endocarditis |
| KR20230162045A (ko) * | 2021-03-26 | 2023-11-28 | 콘트라펙트 코포레이션 | 그램-음성 박테리아에 대해 활성인 아무린, 리신, 및 리신-항미생물 펩타이드 (amp) 작제물 |
| WO2022236088A1 (en) * | 2021-05-06 | 2022-11-10 | Bioharmony Therapeutics Inc. | Lysin polypeptide compositions and methods of use |
| FR3149209B1 (fr) * | 2023-06-02 | 2026-04-03 | Oreal | Composition cosmétique comprenant une endolysine dérivée de phage de Staphylococcus aureus et un alcool aromatique |
| FR3149202B1 (fr) * | 2023-06-02 | 2026-04-10 | Oreal | Composition cosmétique comprenant une endolysine dérivée de phage de Staphylococcus aureus et une huile. |
| EP4719330A1 (en) * | 2023-06-02 | 2026-04-08 | L'oreal | Cosmetic composition comprising an endolysin derived from a staphylococcus aureus phage and an aromatic alcohol |
| FR3149203B1 (fr) * | 2023-06-02 | 2026-03-13 | Oreal | Composition anhydre comprenant une endolysine et de l’hydroxypropylmethylcellulose et/ou du pullulane |
| WO2024256710A2 (en) | 2023-06-15 | 2024-12-19 | Aurobac Therapeutics Sas | Engineered lysin polypeptide constructs active against gram-negative bacteria |
| WO2025054593A2 (en) * | 2023-09-07 | 2025-03-13 | The Trustees Of The University Of Pennsylvania | Molecular de-extinction of antibiotics enabled by deep learning |
| CN120924524B (zh) * | 2025-10-14 | 2026-01-06 | 中国海洋大学 | 一种抗菌肽及其制备方法和在制备治疗肺炎的制剂中的应用 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0517477A (pt) | 2004-11-12 | 2008-10-07 | Novozymes As | polipeptìdeo, construção de ácido nucleico, vetor de expressão recombinante, célula hospedeira recombinante, métodos para produzir um polipeptìdeo, um polinucleotìdeo, e uma proteìna, planta, parte de planta ou célula vegetal transgênicas, método para matar ou inibir o crescimento de células microbianas, e, uso de um polipeptìdeo antimicrobiano |
| SG176783A1 (en) | 2009-06-16 | 2012-01-30 | Univ Tokai | Anti-gram-negative bacteria agent |
| PL2445515T3 (pl) * | 2009-06-26 | 2016-10-31 | Środki przeciwdrobnoustrojowe | |
| AU2010264659B2 (en) * | 2009-06-26 | 2016-08-04 | Lysando Aktiengesellschaft | Antimicrobial agents |
| KR20120059576A (ko) | 2009-08-24 | 2012-06-08 | 뤼산도 홀딩 아게 | 신규한 엔도리신 ＯＢＰｇｐＬＹＳ |
| EP2468856A1 (en) | 2010-12-23 | 2012-06-27 | Lysando Aktiengesellschaft | Antimicrobial Agents |
| EP2699689A4 (en) | 2011-04-21 | 2014-12-17 | Univ Utrecht Holding Bv | STREPTOCOCCUS BACTERIOPHAGEN LYSINE FOR THE TREATMENT OF GRAM-POSITIVE BACTERIA IN PETS AND UTILITIES |
| EP2702070B1 (en) | 2011-04-27 | 2015-09-30 | Lysando AG | New antimicrobial agents |
| WO2012159774A1 (en) | 2011-05-26 | 2012-11-29 | Dsm Ip Assets B.V. | Novel listeria bacteriophage p825n and uses thereof |
| US8790639B2 (en) | 2012-03-28 | 2014-07-29 | The United States Of America, As Represented By The Secretary Of Agriculture | Enhanced antimicrobial lytic activity of a chimeric Ply187 endolysin |
| KR101391332B1 (ko) | 2012-05-18 | 2014-05-07 | 연세대학교 산학협력단 | 카바페넴 제제에 내성을 보이는 아시네토박터 속의 균을 용균하는 박테리오파아지 |
| US9388400B2 (en) * | 2012-06-29 | 2016-07-12 | Lysando Ag | Composition for use in mycobacteria diagnosis |
| CN102861324A (zh) * | 2012-10-17 | 2013-01-09 | 重庆市第三人民医院 | 治疗耐碳青霉烯类鲍曼不动杆菌感染的生物试剂 |
| WO2015200783A2 (en) | 2014-06-26 | 2015-12-30 | The Rockefeller University | Acinetobacter lysins |
| EP4115897A1 (en) | 2015-09-17 | 2023-01-11 | Contrafect Corporation | Use of lysin to restore/augment antibacterial activity in the presence of pulmonary surfactant of antibiotics inhibited thereby |
| KR102000120B1 (ko) | 2017-01-26 | 2019-07-15 | 주식회사 코미팜 | 이유 자돈의 대장균증을 예방하기 위한 재조합 p22 라이소자임 - pmap36 융합 단백질을 이용한 장내독소형 대장균(etec) 고스트 백신 조성물 |
| WO2019118632A1 (en) | 2017-12-12 | 2019-06-20 | Contrafect Corporation | Identification of lysins and derivatives thereof with bacterial activity against pseudomonas aeruginosa |
| US20210330738A1 (en) | 2018-03-29 | 2021-10-28 | Contrafect Corporation | Antimicrobial, bacteriophage-derived polypeptides and their use against gram-negative bacteria |
| WO2019191633A2 (en) | 2018-03-29 | 2019-10-03 | Contrafect Corporation | Lysin-antimicrobial peptide (amp) polypeptide constructs, lysins, isolated polynucleotides encoding same and uses thereof |
| US10988520B2 (en) | 2018-03-29 | 2021-04-27 | Contrafect Corporation | Lysin-antimicrobial peptide (AMP) polypeptide constructs, lysins, isolated polynucleotides encoding same and uses thereof |
| EP3840771A4 (en) * | 2018-08-23 | 2023-04-19 | Contrafect Corporation | Lysin-antimicrobial peptide (amp) polypeptide constructs, lysins, isolated polynucleotides encoding same and uses thereof |
| US20210324359A1 (en) * | 2020-04-17 | 2021-10-21 | Contrafect Corporation | Use of gram-negative lysin-antimicrobial peptide (amp) polypeptide constructs in treating endocarditis |
-
2019
- 2019-03-29 WO PCT/US2019/024912 patent/WO2019191633A2/en not_active Ceased
- 2019-03-29 BR BR112020019484-0A patent/BR112020019484A2/pt unknown
- 2019-03-29 CN CN201980036007.XA patent/CN112368376A/zh active Pending
- 2019-03-29 IL IL277119A patent/IL277119B2/en unknown
- 2019-03-29 KR KR1020207031049A patent/KR20200136980A/ko active Pending
- 2019-03-29 JP JP2020551860A patent/JP2021519083A/ja active Pending
- 2019-03-29 EP EP19776817.9A patent/EP3775192A4/en not_active Withdrawn
- 2019-03-29 AU AU2019245369A patent/AU2019245369A1/en not_active Abandoned
- 2019-03-29 CA CA3095484A patent/CA3095484A1/en active Pending
- 2019-03-29 MX MX2020010075A patent/MX2020010075A/es unknown
- 2019-03-29 US US17/041,691 patent/US11773140B2/en active Active
-
2023
- 2023-08-18 US US18/452,038 patent/US20240018192A1/en active Pending
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