JP2022526978A5 - - Google Patents

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Publication number
JP2022526978A5
JP2022526978A5 JP2021559092A JP2021559092A JP2022526978A5 JP 2022526978 A5 JP2022526978 A5 JP 2022526978A5 JP 2021559092 A JP2021559092 A JP 2021559092A JP 2021559092 A JP2021559092 A JP 2021559092A JP 2022526978 A5 JP2022526978 A5 JP 2022526978A5
Authority
JP
Japan
Prior art keywords
gram
antibiotic
polypeptide
negative
combination preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021559092A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022526978A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/026681 external-priority patent/WO2020206327A1/en
Publication of JP2022526978A publication Critical patent/JP2022526978A/ja
Publication of JP2022526978A5 publication Critical patent/JP2022526978A5/ja
Pending legal-status Critical Current

Links

JP2021559092A 2019-04-05 2020-04-03 ヒト血清の存在下でシュードモナス・エルギノーサに対する殺菌活性を有する溶解素及びその誘導体 Pending JP2022526978A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962830207P 2019-04-05 2019-04-05
US62/830,207 2019-04-05
PCT/US2020/026681 WO2020206327A1 (en) 2019-04-05 2020-04-03 Lysins and derivatives thereof with bactericidal activity against pseudomonas aeruginosa, in the presence of human serum

Publications (2)

Publication Number Publication Date
JP2022526978A JP2022526978A (ja) 2022-05-27
JP2022526978A5 true JP2022526978A5 (https=) 2023-03-27

Family

ID=72667504

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021559092A Pending JP2022526978A (ja) 2019-04-05 2020-04-03 ヒト血清の存在下でシュードモナス・エルギノーサに対する殺菌活性を有する溶解素及びその誘導体

Country Status (11)

Country Link
US (1) US20220160843A1 (https=)
EP (1) EP3946609A4 (https=)
JP (1) JP2022526978A (https=)
KR (1) KR20210148320A (https=)
CN (1) CN114040773A (https=)
AU (1) AU2020256258A1 (https=)
BR (1) BR112021019430A2 (https=)
CA (1) CA3136126A1 (https=)
IL (1) IL286941A (https=)
MX (1) MX2021012166A (https=)
WO (1) WO2020206327A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CU24750B1 (es) * 2020-11-19 2025-06-11 Centro De Investig Y Desarrollo De Medicamentos Cidem Entidades peptídicas con actividad antimicrobiana frente a patógenos multi-drogoresistentes
CN116200418A (zh) * 2021-12-01 2023-06-02 华南农业大学 一种筛选铜绿假单胞菌LasR基因调控网络未知基因突变体的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5701777B2 (ja) * 2009-02-06 2015-04-15 テクノファージ， インベスティガサン エ デセンボルビメント エム ビオテクノロジア，エスエー 抗菌性ファージ、ファージペプチド、及びそれらの使用方法
CA2833409A1 (en) * 2011-04-21 2012-10-26 The Rockefeller University Streptococcus bacteriophage lysins for detection and treatment of gram positive bacteria
AU2015279705B2 (en) * 2014-06-26 2021-04-01 The Rockefeller University Acinetobacter lysins
AU2016324307B2 (en) * 2015-09-17 2021-10-21 Contrafect Corporation Use of lysin to restore/augment antibacterial activity in the presence of pulmonary surfactant of antibiotics inhibited thereby
BR112020011433A2 (pt) * 2017-12-12 2020-12-01 Contrafect Corporation identificação de lisinas e seus derivados com atividade bacteriana contra pseudomonas aeruginosa
CN108103050A (zh) * 2018-02-11 2018-06-01 中国医药集团总公司四川抗菌素工业研究所 一种铜绿假单胞菌噬菌体裂解酶、其编码基因、重组表达载体及其制备方法和应用
CN112368376A (zh) * 2018-03-29 2021-02-12 康特拉费克特公司 溶素-抗微生物肽(amp)多肽构建体、溶素、其分离的编码多核苷酸及其用途
WO2020046747A1 (en) * 2018-08-23 2020-03-05 Contrafect Corporation Lysin-antimicrobial peptide (amp) polypeptide constructs, lysins, isolated polynucleotides encoding same and uses thereof

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