JP2021517471A5 - - Google Patents
Info
- Publication number
- JP2021517471A5 JP2021517471A5 JP2020568946A JP2020568946A JP2021517471A5 JP 2021517471 A5 JP2021517471 A5 JP 2021517471A5 JP 2020568946 A JP2020568946 A JP 2020568946A JP 2020568946 A JP2020568946 A JP 2020568946A JP 2021517471 A5 JP2021517471 A5 JP 2021517471A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amino acid
- composition
- acid sequence
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024001725A JP2024050594A (ja) | 2018-03-02 | 2024-01-10 | 変異ｋｒａｓ配列及び脂質を含む化合物並びにその使用 |
| JP2025283313A JP2026067877A (ja) | 2018-03-02 | 2025-12-26 | 変異ｋｒａｓ配列及び脂質を含む化合物並びにその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862637879P | 2018-03-02 | 2018-03-02 | |
| US62/637,879 | 2018-03-02 | ||
| PCT/US2019/020404 WO2019169332A1 (en) | 2018-03-02 | 2019-03-01 | Compounds including a mutant kras sequence and a lipid and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024001725A Division JP2024050594A (ja) | 2018-03-02 | 2024-01-10 | 変異ｋｒａｓ配列及び脂質を含む化合物並びにその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021517471A JP2021517471A (ja) | 2021-07-26 |
| JP2021517471A5 true JP2021517471A5 (https=) | 2022-03-09 |
| JP7419268B2 JP7419268B2 (ja) | 2024-01-22 |
Family
ID=67805548
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020568946A Active JP7419268B2 (ja) | 2018-03-02 | 2019-03-01 | 変異ｋｒａｓ配列及び脂質を含む化合物並びにその使用 |
| JP2024001725A Pending JP2024050594A (ja) | 2018-03-02 | 2024-01-10 | 変異ｋｒａｓ配列及び脂質を含む化合物並びにその使用 |
| JP2025283313A Pending JP2026067877A (ja) | 2018-03-02 | 2025-12-26 | 変異ｋｒａｓ配列及び脂質を含む化合物並びにその使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024001725A Pending JP2024050594A (ja) | 2018-03-02 | 2024-01-10 | 変異ｋｒａｓ配列及び脂質を含む化合物並びにその使用 |
| JP2025283313A Pending JP2026067877A (ja) | 2018-03-02 | 2025-12-26 | 変異ｋｒａｓ配列及び脂質を含む化合物並びにその使用 |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US12138301B2 (https=) |
| EP (1) | EP3758713A4 (https=) |
| JP (3) | JP7419268B2 (https=) |
| KR (2) | KR102787353B1 (https=) |
| CN (2) | CN118421594A (https=) |
| AU (1) | AU2019226586B2 (https=) |
| BR (1) | BR112020017645A2 (https=) |
| CA (1) | CA3092679A1 (https=) |
| IL (1) | IL277100B2 (https=) |
| MA (1) | MA52435A (https=) |
| MX (2) | MX2020009149A (https=) |
| MY (1) | MY207748A (https=) |
| SA (1) | SA520420064B1 (https=) |
| SG (1) | SG11202008433QA (https=) |
| WO (1) | WO2019169332A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MA52434A (fr) * | 2018-03-02 | 2021-01-06 | Elicio Therapeutics Inc | Amphiphiles cpg et leurs utilisations |
| JP7419268B2 (ja) | 2018-03-02 | 2024-01-22 | エリシオ セラピューティクス， インク． | 変異ｋｒａｓ配列及び脂質を含む化合物並びにその使用 |
| CN116867799A (zh) * | 2021-02-10 | 2023-10-10 | 上海吉倍生物技术有限公司 | Ras G13D突变体表位肽及识别Ras G13D突变体的T细胞受体 |
| KR102818249B1 (ko) | 2021-11-11 | 2025-06-10 | 의료법인 명지의료재단 | Kras 특이적 활성화 t 세포 유도용 항원 조성물을 이용한 항원 특이적 t 세포 유도방법 |
| KR102753583B1 (ko) | 2021-11-11 | 2025-01-10 | 의료법인 명지의료재단 | Kras 특이적 활성화 t 세포 유도용 항원 조성물 |
| KR102732911B1 (ko) | 2021-12-29 | 2024-11-20 | 의료법인 명지의료재단 | K-ras 특이적 활성화 T 세포를 포함하는 유방암의 예방 및 치료용 약제학적 조성물 및 이의 제조방법 |
| KR102732913B1 (ko) | 2021-12-29 | 2024-11-20 | 의료법인 명지의료재단 | K-ras 특이적 활성화 T 세포를 포함하는 흑색종의 예방 및 치료용 약제학적 조성물 및 이의 제조방법 |
| KR102732910B1 (ko) | 2021-12-29 | 2024-11-20 | 의료법인 명지의료재단 | K-ras 특이적 활성화 T 세포를 포함하는 대장암의 예방 및 치료용 약제학적 조성물 및 이의 제조방법 |
| KR102732912B1 (ko) | 2021-12-29 | 2024-11-20 | 의료법인 명지의료재단 | K-ras 특이적 활성화 T 세포를 포함하는 폐 선암종의 예방 및 치료용 약제학적 조성물 및 이의 제조방법 |
| KR102732909B1 (ko) | 2021-12-29 | 2024-11-20 | 의료법인 명지의료재단 | K-ras 특이적 활성화 T 세포를 포함하는 폐 유두상 선암종의 예방 및 치료용 약제학적 조성물 및 이의 제조방법 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6168778B1 (en) * | 1990-06-11 | 2001-01-02 | Nexstar Pharmaceuticals, Inc. | Vascular endothelial growth factor (VEGF) Nucleic Acid Ligand Complexes |
| GB9103974D0 (en) * | 1991-02-26 | 1991-04-10 | Norsk Hydro As | Therapeutically useful peptides or peptide fragments |
| US6207646B1 (en) * | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US7709002B1 (en) | 1996-04-19 | 2010-05-04 | The United States Of America As Represented By The Department Of Health And Human Services | Mutated ras peptides for generation of CD8+Cytotoxic T lymphocytes |
| ES2180045T3 (es) * | 1996-04-19 | 2003-02-01 | Us Gov Sec Health | Peptidos ras mutados para la generacion de linfocitos t citotoxicos cd8+. |
| WO2005001116A1 (ja) | 2003-06-17 | 2005-01-06 | Meiji Dairies Corporation | Toll様レセプター強制発現細胞の利用 |
| WO2005065239A2 (en) | 2003-12-31 | 2005-07-21 | Centocor, Inc. | Novel recombinant proteins with n-terminal free thiol |
| WO2008147956A2 (en) | 2007-05-25 | 2008-12-04 | Centocor, Inc. | Toll-like receptor 3 modulators and uses thereof |
| WO2011036557A1 (en) | 2009-09-22 | 2011-03-31 | The University Of British Columbia | Compositions and methods for enhancing cellular uptake and intracellular delivery of lipid particles |
| US20120328701A1 (en) * | 2011-01-24 | 2012-12-27 | Anterios, Inc. | Nanoparticle compositions, formulations thereof, and uses therefor |
| JP6375289B2 (ja) | 2012-04-05 | 2018-08-15 | マサチューセッツ インスティテュート オブ テクノロジー | 免疫刺激組成物およびその使用方法 |
| ES3039913T3 (en) * | 2012-05-09 | 2025-10-27 | Gradalis Inc | Bi-functional short-hairpin rna (bi-shrna) specific for single-nucleotide kras mutations |
| CA2878314A1 (en) * | 2012-07-16 | 2014-01-23 | Kyowa Hakko Kirin Co., Ltd. | Rnai pharmaceutical composition for suppressing expression of kras gene |
| AR095882A1 (es) | 2013-04-22 | 2015-11-18 | Hoffmann La Roche | Terapia de combinación de anticuerpos contra csf-1r humano con un agonista de tlr9 |
| EP3061547B1 (en) | 2013-10-24 | 2019-12-04 | Daicel Corporation | Method for producing dispersion liquid containing silver nanoparticles, and dispersion liquid containing silver nanoparticles |
| US20170246288A1 (en) * | 2014-09-11 | 2017-08-31 | Vedantra Pharmaceuticals, Inc. | Multilamellar lipid vesicle compositions and methods of use |
| US10940201B2 (en) | 2015-09-30 | 2021-03-09 | Shionogi & Co., Ltd. | Nucleic acid derivative having immunostimulatory activity |
| WO2017127473A1 (en) * | 2016-01-19 | 2017-07-27 | The University Of North Carolina At Chapel Hill | Methods and compositions using rna interference for inhibition of kras |
| CA3035591A1 (en) | 2016-11-30 | 2018-06-07 | Advaxis, Inc. | Immunogenic compositions targeting recurrent cancer mutations and methods of use thereof |
| WO2018154010A1 (en) | 2017-02-23 | 2018-08-30 | Alpha-O Peptides Ag | Self-assembling protein nanoparticles encapsulating immunostimulatory nucleid acids |
| EP3668600B1 (en) * | 2017-08-10 | 2024-05-15 | Abionyx Pharma SA | Cargomers |
| JP7419268B2 (ja) | 2018-03-02 | 2024-01-22 | エリシオ セラピューティクス， インク． | 変異ｋｒａｓ配列及び脂質を含む化合物並びにその使用 |
| MA52434A (fr) | 2018-03-02 | 2021-01-06 | Elicio Therapeutics Inc | Amphiphiles cpg et leurs utilisations |
-
2019
- 2019-03-01 JP JP2020568946A patent/JP7419268B2/ja active Active
- 2019-03-01 MY MYPI2020004500A patent/MY207748A/en unknown
- 2019-03-01 MX MX2020009149A patent/MX2020009149A/es unknown
- 2019-03-01 CN CN202410551083.7A patent/CN118421594A/zh active Pending
- 2019-03-01 EP EP19761691.5A patent/EP3758713A4/en active Pending
- 2019-03-01 AU AU2019226586A patent/AU2019226586B2/en active Active
- 2019-03-01 BR BR112020017645-1A patent/BR112020017645A2/pt unknown
- 2019-03-01 SG SG11202008433QA patent/SG11202008433QA/en unknown
- 2019-03-01 US US16/977,155 patent/US12138301B2/en active Active
- 2019-03-01 MA MA052435A patent/MA52435A/fr unknown
- 2019-03-01 WO PCT/US2019/020404 patent/WO2019169332A1/en not_active Ceased
- 2019-03-01 KR KR1020207028273A patent/KR102787353B1/ko active Active
- 2019-03-01 IL IL277100A patent/IL277100B2/en unknown
- 2019-03-01 KR KR1020257008988A patent/KR20250047830A/ko active Pending
- 2019-03-01 CN CN201980028790.5A patent/CN112118847B/zh active Active
- 2019-03-01 CA CA3092679A patent/CA3092679A1/en active Pending
-
2020
- 2020-08-31 SA SA520420064A patent/SA520420064B1/ar unknown
- 2020-09-02 MX MX2025011341A patent/MX2025011341A/es unknown
-
2024
- 2024-01-10 JP JP2024001725A patent/JP2024050594A/ja active Pending
- 2024-09-11 US US18/882,166 patent/US20250009888A1/en not_active Abandoned
-
2025
- 2025-04-23 US US19/186,849 patent/US20250249107A1/en not_active Abandoned
- 2025-11-26 US US19/401,735 patent/US20260077049A1/en active Pending
- 2025-12-26 JP JP2025283313A patent/JP2026067877A/ja active Pending
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