JP2021517152A5 - - Google Patents

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Publication number
JP2021517152A5
JP2021517152A5 JP2020549021A JP2020549021A JP2021517152A5 JP 2021517152 A5 JP2021517152 A5 JP 2021517152A5 JP 2020549021 A JP2020549021 A JP 2020549021A JP 2020549021 A JP2020549021 A JP 2020549021A JP 2021517152 A5 JP2021517152 A5 JP 2021517152A5
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JP
Japan
Prior art keywords
drug
acid sequence
seq
amino acid
cdr
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JP2020549021A
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English (en)
Japanese (ja)
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JP7691823B2 (ja
JP2021517152A (ja
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Priority claimed from PCT/IL2019/050292 external-priority patent/WO2019175885A1/en
Publication of JP2021517152A publication Critical patent/JP2021517152A/ja
Publication of JP2021517152A5 publication Critical patent/JP2021517152A5/ja
Application granted granted Critical
Publication of JP7691823B2 publication Critical patent/JP7691823B2/ja
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JP2020549021A 2018-03-15 2019-03-14 可溶性免疫受容体cd28を減少させるための方法および組成物 Active JP7691823B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201862643334P 2018-03-15 2018-03-15
US201862643355P 2018-03-15 2018-03-15
US62/643,334 2018-03-15
US62/643,355 2018-03-15
US201862774254P 2018-12-02 2018-12-02
US62/774,254 2018-12-02
PCT/IL2019/050292 WO2019175885A1 (en) 2018-03-15 2019-03-14 Methods and compositions for decreasing soluble immune receptor cd28

Publications (3)

Publication Number Publication Date
JP2021517152A JP2021517152A (ja) 2021-07-15
JP2021517152A5 true JP2021517152A5 (enExample) 2022-03-23
JP7691823B2 JP7691823B2 (ja) 2025-06-12

Family

ID=66182618

Family Applications (1)

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JP2020549021A Active JP7691823B2 (ja) 2018-03-15 2019-03-14 可溶性免疫受容体cd28を減少させるための方法および組成物

Country Status (10)

Country Link
US (2) US12139534B2 (enExample)
EP (1) EP3765518A1 (enExample)
JP (1) JP7691823B2 (enExample)
KR (1) KR20200131260A (enExample)
CN (2) CN119775419A (enExample)
AU (1) AU2019234183B2 (enExample)
BR (1) BR112020018279A2 (enExample)
CA (1) CA3093647A1 (enExample)
IL (1) IL277354B2 (enExample)
WO (1) WO2019175885A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2019234183B2 (en) 2018-03-15 2025-12-18 Biond Biologics Ltd. Methods and compositions for decreasing soluble immune receptor CD28
EP3938397A1 (en) 2019-03-14 2022-01-19 Biond Biologics Ltd. Small shedding blocking agents
CA3130348A1 (en) * 2019-03-14 2020-09-17 Motti HAKIM A method for immunosuppression
WO2021111442A1 (en) 2019-12-02 2021-06-10 Biond Biologics Ltd. Soluble cd28 levels during immunotherapy
JP2023509803A (ja) * 2019-12-02 2023-03-09 ビオンド バイオロジクス リミテッド Mmp抑制の使用
US20230221325A1 (en) * 2019-12-02 2023-07-13 Biond Biologics Ltd. Soluble cd28 levels after immunotherapy
CN115515982A (zh) * 2020-03-12 2022-12-23 比昂生物制剂公司 具有增加的稳定性的脱落阻断剂
EP4399229A2 (en) 2021-09-06 2024-07-17 Biond Biologics Ltd. Cd28 shedding blocking agents
EP4499706A2 (en) * 2022-03-31 2025-02-05 Sana Biotechnology, Inc. Cd4-specific antibody constructs and compositions and uses thereof
WO2025149029A1 (zh) * 2024-01-12 2025-07-17 信达生物制药(苏州)有限公司 抗cd28抗体及其用途
WO2025215647A1 (en) 2024-04-11 2025-10-16 Biond Biologics Ltd. Combination cancer treatment with staggered dosing

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US4235871A (en) 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4501728A (en) 1983-01-06 1985-02-26 Technology Unlimited, Inc. Masking of liposomes from RES recognition
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4666828A (en) 1984-08-15 1987-05-19 The General Hospital Corporation Test for Huntington's disease
US5019369A (en) 1984-10-22 1991-05-28 Vestar, Inc. Method of targeting tumors in humans
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4801531A (en) 1985-04-17 1989-01-31 Biotechnology Research Partners, Ltd. Apo AI/CIII genomic polymorphisms predictive of atherosclerosis
US4837028A (en) 1986-12-24 1989-06-06 Liposome Technology, Inc. Liposomes with enhanced circulation time
US5272057A (en) 1988-10-14 1993-12-21 Georgetown University Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
US5464764A (en) 1989-08-22 1995-11-07 University Of Utah Research Foundation Positive-negative selection methods and vectors
US5192659A (en) 1989-08-25 1993-03-09 Genetype Ag Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes
US5641870A (en) 1995-04-20 1997-06-24 Genentech, Inc. Low pH hydrophobic interaction chromatography for antibody purification
DK1345969T3 (da) 2000-12-26 2010-11-29 Inst Nat Sante Rech Med Anti-CD28-antistof
CN1294148C (zh) * 2001-04-11 2007-01-10 中国科学院遗传与发育生物学研究所 环状单链三特异抗体
IL148993A0 (en) 2002-04-04 2002-11-10 Yissum Res Dev Co Broad-spectrum in-vivo effective superantigen toxin antagonists based on the interaction between cd28 and the superantigen and uses thereof
EP1622569B1 (en) 2003-04-24 2015-12-02 Incyte Corporation Aza spiro alkane derivatives as inhibitors of metallproteases
GB0400440D0 (en) 2004-01-09 2004-02-11 Isis Innovation Receptor modulators
CN100509849C (zh) 2005-04-07 2009-07-08 苏州大学 可溶性人cd28分子检测试剂盒及其应用
PE20110385A1 (es) 2008-07-18 2011-06-22 Bristol Myers Squibb Co Anticuerpo de dominio (dab) que se une a cd28 y no reacciona en forma cruzada con ctla4
AU2019234183B2 (en) 2018-03-15 2025-12-18 Biond Biologics Ltd. Methods and compositions for decreasing soluble immune receptor CD28

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