JP2021515775A5 - - Google Patents
Info
- Publication number
- JP2021515775A5 JP2021515775A5 JP2020547008A JP2020547008A JP2021515775A5 JP 2021515775 A5 JP2021515775 A5 JP 2021515775A5 JP 2020547008 A JP2020547008 A JP 2020547008A JP 2020547008 A JP2020547008 A JP 2020547008A JP 2021515775 A5 JP2021515775 A5 JP 2021515775A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- optionally substituted
- group
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023170366A JP2023165998A (ja) | 2018-03-09 | 2023-09-29 | 優先投与される免疫増強薬 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862641003P | 2018-03-09 | 2018-03-09 | |
| US62/641,003 | 2018-03-09 | ||
| US201862700548P | 2018-07-19 | 2018-07-19 | |
| US62/700,548 | 2018-07-19 | ||
| PCT/US2019/021300 WO2019173682A1 (en) | 2018-03-09 | 2019-03-08 | Parenterally administered immune enhancing drugs |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023170366A Division JP2023165998A (ja) | 2018-03-09 | 2023-09-29 | 優先投与される免疫増強薬 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021515775A JP2021515775A (ja) | 2021-06-24 |
| JP2021515775A5 true JP2021515775A5 (enExample) | 2022-03-16 |
| JP7417530B2 JP7417530B2 (ja) | 2024-01-18 |
Family
ID=67846288
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020547008A Active JP7417530B2 (ja) | 2018-03-09 | 2019-03-08 | 優先投与される免疫増強薬 |
| JP2023170366A Withdrawn JP2023165998A (ja) | 2018-03-09 | 2023-09-29 | 優先投与される免疫増強薬 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023170366A Withdrawn JP2023165998A (ja) | 2018-03-09 | 2023-09-29 | 優先投与される免疫増強薬 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US12433836B2 (enExample) |
| EP (1) | EP3761993A4 (enExample) |
| JP (2) | JP7417530B2 (enExample) |
| KR (1) | KR102822181B1 (enExample) |
| CN (1) | CN112004541A (enExample) |
| AU (1) | AU2019231781B2 (enExample) |
| CA (1) | CA3092585A1 (enExample) |
| WO (1) | WO2019173682A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT3399984T (lt) | 2016-01-08 | 2023-11-10 | Arcus Biosciences, Inc. | 5'-nukleotidazės, ekto moduliatoriai ir jų panaudojimas |
| MX2021002878A (es) * | 2018-09-11 | 2021-08-16 | Risen Suzhou Pharma Tech Co Ltd | Inhibidores de cd73 y usos farmaceuticos de los mismos. |
| US11530234B2 (en) | 2018-09-11 | 2022-12-20 | Risen (Suzhou) Pharma Tech Co., Ltd. | CD73 inhibitors and pharmaceutical uses thereof |
| US12673969B2 (en) | 2018-09-11 | 2026-07-07 | Risen (Suzhou) Pharma Tech Co., Ltd. | CD73 inhibitors and pharmaceutical uses thereof |
| EP3893891A4 (en) | 2018-12-13 | 2022-08-03 | Arcus Biosciences, Inc. | SOLID FORMS OF A CD73 INHIBITOR AND THEIR USE |
| ES3070946T3 (en) | 2019-03-12 | 2026-06-18 | Arcus Biosciences Inc | Treatment of an oncogenene driven cancer having a kras or egfr mutation by decreasing adenosine production or antagonizing adenosine activation |
| CA3135487A1 (en) | 2019-03-29 | 2020-10-08 | Arcus Biosciences, Inc. | Treatment of cancer utilizing an identified adenosine fingerprint |
| TWI821559B (zh) * | 2019-04-28 | 2023-11-11 | 大陸商上海和譽生物醫藥科技有限公司 | 一種cd73抑制劑，其製備方法和應用 |
| TW202131932A (zh) * | 2019-11-05 | 2021-09-01 | 美商博奥阿迪斯有限公司 | 作為cd73抑制劑的化合物 |
| AU2021213969A1 (en) * | 2020-01-30 | 2022-09-01 | ONA Therapeutics S.L. | Combination therapy for treatment of cancer and cancer metastasis |
| TWI794742B (zh) | 2020-02-18 | 2023-03-01 | 美商基利科學股份有限公司 | 抗病毒化合物 |
| TWI775313B (zh) | 2020-02-18 | 2022-08-21 | 美商基利科學股份有限公司 | 抗病毒化合物 |
| KR20250133471A (ko) | 2020-02-18 | 2025-09-05 | 길리애드 사이언시즈, 인코포레이티드 | 항바이러스 화합물 |
| US11633416B1 (en) | 2020-03-06 | 2023-04-25 | Arcus Biosciences, Inc. | Oral formulations of CD73 compounds |
| CA3179320A1 (en) | 2020-06-17 | 2021-12-23 | Arcus Biosciences, Inc. | Crystalline forms of a cd73 inhibitor and uses thereof |
| AU2022256476B2 (en) | 2021-04-16 | 2025-06-05 | Gilead Sciences, Inc. | Methods of preparing carbanucleosides using amides |
| TW202308657A (zh) * | 2021-05-11 | 2023-03-01 | 大陸商四川海思科製藥有限公司 | 小分子cd73拮抗劑及其用途 |
| CA3228162A1 (en) | 2021-08-18 | 2023-02-23 | Gilead Sciences, Inc. | Phospholipid compounds and methods of making and using the same |
| EP4422643A4 (en) | 2021-10-26 | 2025-11-26 | Southern Res Inst | DEVELOPMENT OF NEW CLOFARABINE ANALOGUES FOR CANCER THERAPY |
| EP4541803A4 (en) * | 2022-06-17 | 2025-10-01 | Shanghai Senhui Medicine Co Ltd | CYCLOPENTYLADENOSINE DERIVATIVE AND ITS PHARMACEUTICAL USE |
| CN120091809A (zh) * | 2022-10-20 | 2025-06-03 | 艾库斯生物科学有限公司 | Cd73化合物的冻干制剂 |
| CN117924394B (zh) * | 2023-09-05 | 2026-07-24 | 厦门大学 | 核苷酸类化合物及其制备方法和应用、核素靶向探针及其制备方法和应用、药物组合物 |
| CN117562915A (zh) * | 2023-12-05 | 2024-02-20 | 中国药科大学 | 一种腺苷衍生物在制备预防、缓解或治疗纤维化疾病的药物中的应用 |
| CN120285176A (zh) * | 2025-04-25 | 2025-07-11 | 谈高 | 抗CD73单抗联合Adora1抑制剂在治疗肠纤维化中的应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5569650A (en) * | 1993-06-11 | 1996-10-29 | Sloan-Kettering Institute For Cancer Research | C-nucleoside isosters of analogs thereof and pharmaceutical compositions |
| EP1259234B9 (en) | 1999-12-30 | 2007-02-14 | Sugen, Inc. | 3-heteroarylidenyl-2-indolinone compounds for modulating protein kinase activity and for use in cancer chemotherapy |
| US9090697B2 (en) | 2013-03-15 | 2015-07-28 | Bayer Healthcare Llc | Methods for treating bleeding disorders |
| EP3134411B1 (en) * | 2014-04-25 | 2021-06-30 | Boehringer Ingelheim International GmbH | Purine derivatives as cd73 inhibitors for the treatment of cancer |
| LT3399984T (lt) * | 2016-01-08 | 2023-11-10 | Arcus Biosciences, Inc. | 5'-nukleotidazės, ekto moduliatoriai ir jų panaudojimas |
| AU2017228470A1 (en) | 2016-03-04 | 2018-08-30 | Bristol-Myers Squibb Company | Combination therapy with anti-CD73 antibodies |
| WO2018047139A1 (en) * | 2016-09-12 | 2018-03-15 | Aurigene Discovery Technologies Limited | Compounds as modulators of tigit signalling pathway |
| WO2018067424A1 (en) | 2016-10-03 | 2018-04-12 | Arcus Biosciences, Inc. | Inhibitors of adenosine 5'-nucleotidase |
| CN110022881B (zh) | 2016-11-18 | 2023-05-02 | 艾库斯生物科学有限公司 | Cd73介导的免疫抑制的抑制剂 |
| TW202012637A (zh) * | 2018-04-24 | 2020-04-01 | 瑞典商阿斯特捷利康公司 | 治療癌症之方法 |
| EP3893891A4 (en) * | 2018-12-13 | 2022-08-03 | Arcus Biosciences, Inc. | SOLID FORMS OF A CD73 INHIBITOR AND THEIR USE |
-
2019
- 2019-03-08 WO PCT/US2019/021300 patent/WO2019173682A1/en not_active Ceased
- 2019-03-08 CN CN201980018034.4A patent/CN112004541A/zh active Pending
- 2019-03-08 CA CA3092585A patent/CA3092585A1/en active Pending
- 2019-03-08 KR KR1020207028869A patent/KR102822181B1/ko active Active
- 2019-03-08 US US16/978,920 patent/US12433836B2/en active Active
- 2019-03-08 EP EP19764884.3A patent/EP3761993A4/en active Pending
- 2019-03-08 JP JP2020547008A patent/JP7417530B2/ja active Active
- 2019-03-08 AU AU2019231781A patent/AU2019231781B2/en active Active
-
2023
- 2023-09-29 JP JP2023170366A patent/JP2023165998A/ja not_active Withdrawn
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