JP2021515775A5 - - Google Patents

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Publication number
JP2021515775A5
JP2021515775A5 JP2020547008A JP2020547008A JP2021515775A5 JP 2021515775 A5 JP2021515775 A5 JP 2021515775A5 JP 2020547008 A JP2020547008 A JP 2020547008A JP 2020547008 A JP2020547008 A JP 2020547008A JP 2021515775 A5 JP2021515775 A5 JP 2021515775A5
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JP
Japan
Prior art keywords
pharmaceutical composition
composition according
optionally substituted
group
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020547008A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021515775A (ja
JP7417530B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/021300 external-priority patent/WO2019173682A1/en
Publication of JP2021515775A publication Critical patent/JP2021515775A/ja
Publication of JP2021515775A5 publication Critical patent/JP2021515775A5/ja
Priority to JP2023170366A priority Critical patent/JP2023165998A/ja
Application granted granted Critical
Publication of JP7417530B2 publication Critical patent/JP7417530B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2020547008A 2018-03-09 2019-03-08 優先投与される免疫増強薬 Active JP7417530B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023170366A JP2023165998A (ja) 2018-03-09 2023-09-29 優先投与される免疫増強薬

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862641003P 2018-03-09 2018-03-09
US62/641,003 2018-03-09
US201862700548P 2018-07-19 2018-07-19
US62/700,548 2018-07-19
PCT/US2019/021300 WO2019173682A1 (en) 2018-03-09 2019-03-08 Parenterally administered immune enhancing drugs

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023170366A Division JP2023165998A (ja) 2018-03-09 2023-09-29 優先投与される免疫増強薬

Publications (3)

Publication Number Publication Date
JP2021515775A JP2021515775A (ja) 2021-06-24
JP2021515775A5 true JP2021515775A5 (OSRAM) 2022-03-16
JP7417530B2 JP7417530B2 (ja) 2024-01-18

Family

ID=67846288

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020547008A Active JP7417530B2 (ja) 2018-03-09 2019-03-08 優先投与される免疫増強薬
JP2023170366A Withdrawn JP2023165998A (ja) 2018-03-09 2023-09-29 優先投与される免疫増強薬

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023170366A Withdrawn JP2023165998A (ja) 2018-03-09 2023-09-29 優先投与される免疫増強薬

Country Status (8)

Country Link
US (1) US12433836B2 (OSRAM)
EP (1) EP3761993A4 (OSRAM)
JP (2) JP7417530B2 (OSRAM)
KR (1) KR102822181B1 (OSRAM)
CN (1) CN112004541A (OSRAM)
AU (1) AU2019231781B2 (OSRAM)
CA (1) CA3092585A1 (OSRAM)
WO (1) WO2019173682A1 (OSRAM)

Families Citing this family (23)

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Publication number Priority date Publication date Assignee Title
SG11201805506YA (en) 2016-01-08 2018-07-30 Arcus Biosciences Inc Modulators of 5'-nucleotidase, ecto and the use thereof
US11530234B2 (en) 2018-09-11 2022-12-20 Risen (Suzhou) Pharma Tech Co., Ltd. CD73 inhibitors and pharmaceutical uses thereof
EP3849992A4 (en) * 2018-09-11 2022-06-29 Risen (Suzhou) Pharma Tech Co., Ltd. Cd73 inhibitors and pharmaceutical uses thereof
EP3893891A4 (en) 2018-12-13 2022-08-03 Arcus Biosciences, Inc. SOLID FORMS OF A CD73 INHIBITOR AND THEIR USE
WO2020185859A1 (en) 2019-03-12 2020-09-17 Arcus Biosciences, Inc. Treatment of oncogene-driven cancers
EP3947463A4 (en) 2019-03-29 2022-12-21 Arcus Biosciences, Inc. TREATMENT OF CANCER USING AN IDENTIFIED ADENOSINE FINGERPRINT
TWI821559B (zh) * 2019-04-28 2023-11-11 大陸商上海和譽生物醫藥科技有限公司 一種cd73抑制劑,其製備方法和應用
TW202131932A (zh) * 2019-11-05 2021-09-01 美商博奥阿迪斯有限公司 作為cd73抑制劑的化合物
US20230086099A1 (en) * 2020-01-30 2023-03-23 Ona Therapeutics, S.L. Combination therapy for treatment of cancer and cancer metastasis
TWI874791B (zh) 2020-02-18 2025-03-01 美商基利科學股份有限公司 抗病毒化合物
AU2021224588B2 (en) 2020-02-18 2024-07-18 Gilead Sciences, Inc. Antiviral compounds
TWI794742B (zh) 2020-02-18 2023-03-01 美商基利科學股份有限公司 抗病毒化合物
US11633416B1 (en) 2020-03-06 2023-04-25 Arcus Biosciences, Inc. Oral formulations of CD73 compounds
AU2021292195A1 (en) 2020-06-17 2023-01-05 Arcus Biosciences, Inc. Crystalline forms of a CD73 inhibitor and uses thereof
JP7688152B2 (ja) 2021-04-16 2025-06-03 ギリアード サイエンシーズ, インコーポレイテッド アミドを使用してカルバヌクレオシドを調製する方法
TW202308657A (zh) * 2021-05-11 2023-03-01 大陸商四川海思科製藥有限公司 小分子cd73拮抗劑及其用途
JP7719954B2 (ja) 2021-08-18 2025-08-06 ギリアード サイエンシーズ, インコーポレイテッド リン脂質化合物並びにその製造方法及び使用方法
WO2023076392A1 (en) 2021-10-26 2023-05-04 Southern Research Institute Development of novel clofarabine analogs for cancer therapy
CN119365476A (zh) * 2022-06-17 2025-01-24 上海森辉医药有限公司 一种环戊基腺苷衍生物及其药物用途
CN120091809A (zh) * 2022-10-20 2025-06-03 艾库斯生物科学有限公司 Cd73化合物的冻干制剂
CN117924394A (zh) * 2023-09-05 2024-04-26 厦门大学 核苷酸类化合物及其制备方法和应用、核素靶向探针及其制备方法和应用、药物组合物
CN117562915A (zh) * 2023-12-05 2024-02-20 中国药科大学 一种腺苷衍生物在制备预防、缓解或治疗纤维化疾病的药物中的应用
CN120285176A (zh) * 2025-04-25 2025-07-11 谈高 抗CD73单抗联合Adora1抑制剂在治疗肠纤维化中的应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5569650A (en) * 1993-06-11 1996-10-29 Sloan-Kettering Institute For Cancer Research C-nucleoside isosters of analogs thereof and pharmaceutical compositions
EP1259234B9 (en) 1999-12-30 2007-02-14 Sugen, Inc. 3-heteroarylidenyl-2-indolinone compounds for modulating protein kinase activity and for use in cancer chemotherapy
US9090697B2 (en) 2013-03-15 2015-07-28 Bayer Healthcare Llc Methods for treating bleeding disorders
EP3134411B1 (en) 2014-04-25 2021-06-30 Boehringer Ingelheim International GmbH Purine derivatives as cd73 inhibitors for the treatment of cancer
SG11201805506YA (en) 2016-01-08 2018-07-30 Arcus Biosciences Inc Modulators of 5'-nucleotidase, ecto and the use thereof
CA3016187A1 (en) 2016-03-04 2017-09-08 Bristol-Myers Squibb Company Combination therapy with anti-cd73 antibodies
WO2018047139A1 (en) * 2016-09-12 2018-03-15 Aurigene Discovery Technologies Limited Compounds as modulators of tigit signalling pathway
EP3518934A4 (en) * 2016-10-03 2020-06-24 Arcus Biosciences, Inc. Inhibitors of adenosine 5'-nucleotidase
JP7150712B2 (ja) 2016-11-18 2022-10-11 アーカス バイオサイエンシズ インコーポレイティド Cd73媒介免疫抑制の阻害剤
EP3893891A4 (en) * 2018-12-13 2022-08-03 Arcus Biosciences, Inc. SOLID FORMS OF A CD73 INHIBITOR AND THEIR USE

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