JP2021515558A5 - - Google Patents

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Publication number
JP2021515558A5
JP2021515558A5 JP2020546854A JP2020546854A JP2021515558A5 JP 2021515558 A5 JP2021515558 A5 JP 2021515558A5 JP 2020546854 A JP2020546854 A JP 2020546854A JP 2020546854 A JP2020546854 A JP 2020546854A JP 2021515558 A5 JP2021515558 A5 JP 2021515558A5
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JP
Japan
Prior art keywords
seq
amino acid
acid sequence
region
cells
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Application number
JP2020546854A
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English (en)
Japanese (ja)
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JP2021515558A (ja
JP7542439B2 (ja
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Priority claimed from PCT/US2019/021681 external-priority patent/WO2019173837A1/en
Publication of JP2021515558A publication Critical patent/JP2021515558A/ja
Publication of JP2021515558A5 publication Critical patent/JP2021515558A5/ja
Priority to JP2023172758A priority Critical patent/JP2023168545A/ja
Application granted granted Critical
Publication of JP7542439B2 publication Critical patent/JP7542439B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2020546854A 2018-03-09 2019-03-11 二量体抗原受容体(dar) Active JP7542439B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023172758A JP2023168545A (ja) 2018-03-09 2023-10-04 二量体抗原受容体(dar)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862640775P 2018-03-09 2018-03-09
US62/640,775 2018-03-09
PCT/US2019/021681 WO2019173837A1 (en) 2018-03-09 2019-03-11 Dimeric antigen receptors (dar)

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023172758A Division JP2023168545A (ja) 2018-03-09 2023-10-04 二量体抗原受容体(dar)

Publications (3)

Publication Number Publication Date
JP2021515558A JP2021515558A (ja) 2021-06-24
JP2021515558A5 true JP2021515558A5 (enExample) 2022-03-04
JP7542439B2 JP7542439B2 (ja) 2024-08-30

Family

ID=67846344

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020546854A Active JP7542439B2 (ja) 2018-03-09 2019-03-11 二量体抗原受容体(dar)
JP2023172758A Pending JP2023168545A (ja) 2018-03-09 2023-10-04 二量体抗原受容体(dar)

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023172758A Pending JP2023168545A (ja) 2018-03-09 2023-10-04 二量体抗原受容体(dar)

Country Status (10)

Country Link
US (1) US12180294B2 (enExample)
EP (1) EP3762430A4 (enExample)
JP (2) JP7542439B2 (enExample)
KR (1) KR20200130395A (enExample)
CN (1) CN112105649B (enExample)
AU (1) AU2019231315A1 (enExample)
CA (1) CA3092993A1 (enExample)
IL (1) IL277181A (enExample)
SG (1) SG11202008568WA (enExample)
WO (1) WO2019173837A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200076732A (ko) * 2017-11-03 2020-06-29 소렌토 쎄라퓨틱스, 인코포레이티드 Cd38-지시된 키메라 항원 수용체 작제물
JP7637510B2 (ja) * 2018-06-20 2025-02-28 ビバソル, インコーポレイテッド Cd38に結合するバリアント抗体
EP3938510A1 (en) 2019-03-11 2022-01-19 Sorrento Therapeutics, Inc. Improved process for integration of dna constructs using rna-guided endonucleases
CN114650829A (zh) * 2019-09-05 2022-06-21 索伦托药业有限公司 结合bcma的二聚体抗原受体(dar)
JP2023516595A (ja) * 2020-02-27 2023-04-20 ソレント・セラピューティクス・インコーポレイテッド Cd20を結合する二量体抗原受容体(dar)
EP4139345A1 (en) 2020-04-24 2023-03-01 Sorrento Therapeutics, Inc. Memory dimeric antigen receptors
WO2022015956A1 (en) 2020-07-15 2022-01-20 Sorrento Therapeutics, Inc. Improved process for dna integration using rna-guided endonucleases
KR102598598B1 (ko) 2020-10-08 2023-11-07 엘티소재주식회사 헤테로고리 화합물, 이를 포함하는 유기 발광 소자, 이의 제조 방법 및 유기 발광 소자의 유기물층용 조성물
CN116601174A (zh) * 2020-10-12 2023-08-15 索伦托药业有限公司 Cd19定向的嵌合抗原受体构建体
IL305175A (en) * 2021-02-19 2023-10-01 Angeles Therapeutics Inc Single-chain and multi-chain synthetic antigen receptors for diverse immune cells
CN112662631B (zh) * 2021-03-16 2021-06-29 合源生物科技(天津)有限公司 一种car-t细胞灌流培养方法
US20240197881A1 (en) * 2021-04-23 2024-06-20 Sorrento Therapeutics, Inc. Dimeric Antigen Receptors (DARs) that Bind GD2
EP4453018A1 (en) * 2021-12-24 2024-10-30 ETH Zurich Multichain antigen-specific receptors for cell-based immunotherapy

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7521053B2 (en) * 2001-10-11 2009-04-21 Amgen Inc. Angiopoietin-2 specific binding agents
US9708384B2 (en) * 2011-09-22 2017-07-18 The Trustees Of The University Of Pennsylvania Universal immune receptor expressed by T cells for the targeting of diverse and multiple antigens
CN113527495A (zh) * 2015-04-08 2021-10-22 索伦托药业有限公司 与cd38结合的抗体治疗剂
US10471098B2 (en) * 2015-04-15 2019-11-12 Prospect Chartercare Rwmc, Llc Hepatic arterial infusion of CAR-T cells
CN107849102B (zh) 2015-05-15 2022-05-13 希望之城 嵌合抗原受体组合物
MX2018004721A (es) * 2015-10-23 2018-07-06 Eureka Therapeutics Inc Construcciones quimericas anticuerpo/receptor de celulas t y usos de las mismas.
WO2017070654A1 (en) * 2015-10-23 2017-04-27 Sorrento Therapeutics, Inc. Programmable universal cell receptors and methods of using the same
US11291721B2 (en) * 2016-03-21 2022-04-05 Marengo Therapeutics, Inc. Multispecific and multifunctional molecules and uses thereof
WO2018075813A1 (en) * 2016-10-19 2018-04-26 City Of Hope Use of endogenous viral vaccine in chimeric antigen receptor t cell therapy
KR20200076732A (ko) 2017-11-03 2020-06-29 소렌토 쎄라퓨틱스, 인코포레이티드 Cd38-지시된 키메라 항원 수용체 작제물
EP3729081B1 (en) 2017-12-21 2025-02-19 F. Hoffmann-La Roche AG Car-t cell assay for specificity test of novel antigen binding moieties
WO2019192973A1 (en) 2018-04-04 2019-10-10 F. Hoffmann-La Roche Ag Diagnostic assays to detect tumor antigens in cancer patients
JP2021520209A (ja) 2018-04-04 2021-08-19 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト 癌患者における腫瘍抗原を検出するための診断アッセイ

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