JP2021515550A5 - - Google Patents

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Publication number
JP2021515550A5
JP2021515550A5 JP2020545529A JP2020545529A JP2021515550A5 JP 2021515550 A5 JP2021515550 A5 JP 2021515550A5 JP 2020545529 A JP2020545529 A JP 2020545529A JP 2020545529 A JP2020545529 A JP 2020545529A JP 2021515550 A5 JP2021515550 A5 JP 2021515550A5
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JP
Japan
Prior art keywords
sequence
indicator
fluorescent
seq
polypeptide
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JP2020545529A
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English (en)
Japanese (ja)
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JP2021515550A (ja
JPWO2019165563A5 (https=
JP7313636B2 (ja
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Priority claimed from PCT/CA2019/050254 external-priority patent/WO2019165563A1/en
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Publication of JP2021515550A5 publication Critical patent/JP2021515550A5/ja
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JP2020545529A 2018-03-02 2019-03-01 興奮性細胞および非興奮性細胞でCa2+を画像化するための低親和性赤色蛍光指示薬 Active JP7313636B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862637808P 2018-03-02 2018-03-02
US62/637,808 2018-03-02
PCT/CA2019/050254 WO2019165563A1 (en) 2018-03-02 2019-03-01 Low affinity red fluorescent indicators for imaging ca2+ in excitable and non-excitable cells

Publications (4)

Publication Number Publication Date
JP2021515550A JP2021515550A (ja) 2021-06-24
JPWO2019165563A5 JPWO2019165563A5 (https=) 2022-03-04
JP2021515550A5 true JP2021515550A5 (https=) 2022-03-04
JP7313636B2 JP7313636B2 (ja) 2023-07-25

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JP2020545529A Active JP7313636B2 (ja) 2018-03-02 2019-03-01 興奮性細胞および非興奮性細胞でCa2+を画像化するための低親和性赤色蛍光指示薬

Country Status (8)

Country Link
US (1) US20210063404A1 (https=)
EP (1) EP3759128A4 (https=)
JP (1) JP7313636B2 (https=)
KR (1) KR102895185B1 (https=)
CN (1) CN112055716B (https=)
CA (1) CA3093019A1 (https=)
SG (1) SG11202007933VA (https=)
WO (1) WO2019165563A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115197301B (zh) * 2022-06-10 2024-07-16 北京师范大学 用于胞内钙信号检测及相关药物筛选的钙指示工具及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1700865A1 (en) * 2005-03-11 2006-09-13 AXXAM S.r.l. Photoproteins with enhanced bioluminescence and their use as intracellular calcium indicators
US20110154515A1 (en) * 2007-08-24 2011-06-23 Oliver Griesbeck Genetically encoded calcium sensors comprising the c-terminal lobe of troponin c and a fluorescence tag
JP6051438B2 (ja) * 2012-06-19 2016-12-27 国立大学法人埼玉大学 赤色蛍光蛋白質を用いたカルシウムセンサー蛋白質
US10836802B2 (en) * 2014-06-11 2020-11-17 Japan Science And Technology Agency Calcium reporter gene
US9644007B2 (en) * 2014-12-23 2017-05-09 Howard Hughes Medical Institute Red genetically encoded calcium indicators and methods of use
CA2997619A1 (en) * 2015-09-15 2017-03-23 The Board Of Trustees Of The Leland Stanford Junior University Light-responsive polypeptides and methods of use thereof
WO2017087542A1 (en) * 2015-11-18 2017-05-26 The Board Of Trustees Of The Leland Stanford Junior University Method and systems for measuring neural activity
CN205757212U (zh) * 2016-06-29 2016-12-07 湖南中烟工业有限责任公司 无棉型超声波雾化器及电子烟
WO2018034298A1 (ja) * 2016-08-16 2018-02-22 国立研究開発法人理化学研究所 カルシウムインジケーターを有する遺伝子改変トリパノソーマ・クルージおよび抗トリパノソーマ薬のスクリーニングのためのその応用
EP3652339A4 (en) * 2017-07-09 2021-04-14 Montana Molecular LLC BIOSENSORS FOR MEASURING CELL SIGNALING IN STRESSED AND HEALTHY CELLS

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