JP2021514185A5 - - Google Patents

Info

Publication number
JP2021514185A5
JP2021514185A5 JP2020543276A JP2020543276A JP2021514185A5 JP 2021514185 A5 JP2021514185 A5 JP 2021514185A5 JP 2020543276 A JP2020543276 A JP 2020543276A JP 2020543276 A JP2020543276 A JP 2020543276A JP 2021514185 A5 JP2021514185 A5 JP 2021514185A5
Authority
JP
Japan
Prior art keywords
cells
notch ligand
cell
positive
cell lineage
Prior art date
Application number
JP2020543276A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021514185A (ja
JPWO2019157597A5 (https=
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CA2019/050181 external-priority patent/WO2019157597A1/en
Publication of JP2021514185A publication Critical patent/JP2021514185A/ja
Publication of JPWO2019157597A5 publication Critical patent/JPWO2019157597A5/ja
Publication of JP2021514185A5 publication Critical patent/JP2021514185A5/ja
Priority to JP2023191915A priority Critical patent/JP2024016217A/ja
Priority to JP2025216743A priority patent/JP2026031647A/ja
Pending legal-status Critical Current

Links

JP2020543276A 2018-02-14 2019-02-14 T細胞系列の細胞を発生させるための方法 Pending JP2021514185A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023191915A JP2024016217A (ja) 2018-02-14 2023-11-10 T細胞系列の細胞を発生させるための方法
JP2025216743A JP2026031647A (ja) 2018-02-14 2025-12-02 T細胞系列の細胞を発生させるための方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862630497P 2018-02-14 2018-02-14
US62/630,497 2018-02-14
PCT/CA2019/050181 WO2019157597A1 (en) 2018-02-14 2019-02-14 Method for generating cells of the t cell lineage

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023191915A Division JP2024016217A (ja) 2018-02-14 2023-11-10 T細胞系列の細胞を発生させるための方法

Publications (3)

Publication Number Publication Date
JP2021514185A JP2021514185A (ja) 2021-06-10
JPWO2019157597A5 JPWO2019157597A5 (https=) 2022-02-10
JP2021514185A5 true JP2021514185A5 (https=) 2022-02-10

Family

ID=67619677

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2020543276A Pending JP2021514185A (ja) 2018-02-14 2019-02-14 T細胞系列の細胞を発生させるための方法
JP2023191915A Pending JP2024016217A (ja) 2018-02-14 2023-11-10 T細胞系列の細胞を発生させるための方法
JP2025216743A Pending JP2026031647A (ja) 2018-02-14 2025-12-02 T細胞系列の細胞を発生させるための方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2023191915A Pending JP2024016217A (ja) 2018-02-14 2023-11-10 T細胞系列の細胞を発生させるための方法
JP2025216743A Pending JP2026031647A (ja) 2018-02-14 2025-12-02 T細胞系列の細胞を発生させるための方法

Country Status (8)

Country Link
US (2) US12467034B2 (https=)
EP (1) EP3752602A4 (https=)
JP (3) JP2021514185A (https=)
KR (1) KR20200121817A (https=)
CN (1) CN112041431A (https=)
AU (2) AU2019220935B2 (https=)
CA (1) CA3091158A1 (https=)
WO (1) WO2019157597A1 (https=)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021514185A (ja) 2018-02-14 2021-06-10 サニーブルック リサーチ インスティチュート T細胞系列の細胞を発生させるための方法
JP2023548115A (ja) * 2020-10-28 2023-11-15 サンガモ セラピューティクス, インコーポレイテッド ヒト多能性幹細胞からのcd4+エフェクターおよび制御性t細胞の生成
WO2022115492A1 (en) * 2020-11-24 2022-06-02 Lyell Immunopharma, Inc. Methods for making, compositions comprising, and methods of using rejuvenated t cells
US11661459B2 (en) 2020-12-03 2023-05-30 Century Therapeutics, Inc. Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
AU2021392032A1 (en) 2020-12-03 2023-06-22 Century Therapeutics, Inc. Genetically engineered cells and uses thereof
KR20230128324A (ko) * 2021-02-05 2023-09-04 고쿠리츠다이가쿠호진 고베다이가쿠 인공 다능성 줄기 세포 유래 γδ T 세포 및 그 제작방법
WO2022216524A1 (en) 2021-04-07 2022-10-13 Century Therapeutics, Inc. Combined artificial cell death/reporter system polypeptide for chimeric antigen receptor cell and uses thereof
CA3210702A1 (en) 2021-04-07 2022-10-13 Century Therapeutics, Inc. Gene transfer vectors and methods of engineering cells
WO2022241558A1 (en) * 2021-05-18 2022-11-24 The University Of British Columbia A method for producing blood progenitor and progenitor t cells, resulting cells and methods and uses thereof
WO2023129937A1 (en) 2021-12-29 2023-07-06 Century Therapeutics, Inc. Genetically engineered cells having anti-cd19 / anti-cd22 chimeric antigen receptors, and uses thereof
IL314801A (en) 2022-02-22 2024-10-01 Juno Therapeutics Inc Proteinase 3 (PR3) Chimeric Autoantigen Receptor T Cells and Related Methods and Uses
CN119365492A (zh) 2022-05-04 2025-01-24 世纪治疗股份有限公司 用hla-e和hla-g转基因工程化的细胞
JP2025522360A (ja) 2022-06-08 2025-07-15 センチュリー セラピューティクス,インコーポレイテッド Cd16変異体およびnkg2dを発現する遺伝子操作した細胞ならびにその使用
CA3257650A1 (en) 2022-06-08 2023-12-14 Century Therapeutics, Inc. Immunoeffector cells derived from genetically modified, multipotential stem cells with membrane IL-12 and their uses
WO2023240212A2 (en) 2022-06-08 2023-12-14 Century Therapeutics, Inc. Genetically engineered cells having anti-cd133 / anti-egfr chimeric antigen receptors, and uses thereof
WO2024102838A1 (en) 2022-11-09 2024-05-16 Century Therapeutics, Inc. Engineered interleukin-7 receptors and uses thereof
KR20250143301A (ko) 2022-11-10 2025-10-01 센츄리 쎄라퓨틱스 인코포레이티드 항-넥틴4 키메라 항원 수용체를 갖는 유전자 조작 세포 및 이의 용도
WO2024156066A1 (en) * 2023-01-27 2024-08-02 Notch Therapeutics (Canada), Inc. Method for generating t cell lineage populations from stem/progenitor cells
WO2025101938A2 (en) 2023-11-10 2025-05-15 Century Therapeutics, Inc. Genetically engineered cells having multi-transmembrane domain chimeric antigen receptors utilizing g protein-coupled receptor scaffolds, and uses thereof
WO2025106626A1 (en) 2023-11-15 2025-05-22 Century Therapeutics, Inc. Genetically engineered cells expressing c-x-c chemokine receptor type 4, and uses thereof
WO2025207798A1 (en) 2024-03-26 2025-10-02 Century Therapeutics, Inc. Genetically engineered cells having anti-cd123 chimeric antigen receptors, and uses thereof
WO2025207795A1 (en) 2024-03-26 2025-10-02 Juno Therapeutics, Inc. Genetically engineered cells having anti-cd33 / anti-cd123 chimeric antigen receptors, and uses thereof
US20250332260A1 (en) 2024-04-10 2025-10-30 Garuda Therapeutics, Inc. Immune compatible cells for allogeneic cell therapies to cover global, ethnic, or disease-specific populations

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100895231B1 (ko) 2002-03-25 2009-05-04 다카라 바이오 가부시키가이샤 세포상해성 림프구의 제조방법
JP2006506322A (ja) 2002-04-05 2006-02-23 ロランティス リミテッド 内科療法
US7575925B2 (en) * 2002-12-10 2009-08-18 Sunnybrook Health Sciences Centre Cell preparations comprising cells of the T cell lineage and methods of making and using them
JP2006517533A (ja) * 2003-01-23 2006-07-27 ロランティス リミテッド Notchシグナル伝達経路のアクチベーターを用いる自己免疫疾患の治療
WO2007027226A2 (en) * 2005-04-28 2007-03-08 Board Of Regents, The University Of Texas System Systems and methods for the production of differentiated cells
EP2321407A4 (en) 2008-09-11 2012-07-18 Univ Florida SYSTEM AND METHOD FOR THE PRODUCTION OF T-CELLS
JP5756017B2 (ja) * 2008-11-07 2015-07-29 サニーブルック ヘルス サイエンシズ センター ヒト前駆t細胞
US8871510B2 (en) 2009-12-03 2014-10-28 University Of Utah Research Foundation Methods for generating T lymphocytes from hematopoietic stem cells
ES2608937T3 (es) 2010-02-22 2017-04-17 Université Pierre Et Marie Curie (Paris 6) Medio de cultivo celular para el crecimiento y diferenciación de células del linaje hematopoyético
CN104053769A (zh) * 2011-11-21 2014-09-17 大学健康网络 造血祖细胞群体和富集其干细胞的方法
US10180254B2 (en) * 2014-09-16 2019-01-15 Hitachi Zosen Inova Ag Method and device for processing slag occurring in a combustion chamber of a refuse incineration plant
FR3026744B1 (fr) * 2014-10-06 2024-04-19 Hopitaux Paris Assist Publique Methode de generation de progeniteurs de cellules t
AU2016211671B2 (en) 2015-01-26 2022-05-26 Fate Therapeutics, Inc. Methods and compositions for inducing hematopoietic cell differentiation
WO2016187459A1 (en) 2015-05-20 2016-11-24 The Regents Of The University Of California Method for generating human dendritic cells for immunotherapy
JP7049261B2 (ja) * 2016-04-08 2022-04-06 ザ ガバニング カウンシル オブ ザ ユニバーシティ オブ トロント 幹細胞および/または前駆細胞からt前駆細胞を作製する方法ならびに該t前駆細胞の使用
US20190134169A1 (en) 2016-04-26 2019-05-09 Temple University-Of The Commonwealth System Of Higher Education DLL4-expressing cells and vaccine using the same
IL268641B2 (en) 2017-02-13 2024-10-01 Assist Publique Hopitaux Paris Aphp Method for generating t cells progenitors
JP2021514185A (ja) 2018-02-14 2021-06-10 サニーブルック リサーチ インスティチュート T細胞系列の細胞を発生させるための方法
EP4326856A4 (en) * 2021-04-23 2025-10-08 Sunnybrook Res Inst STEM CELLS COMPRISING AN UNREARRANGED T CELL RECEPTOR (TCR) GENE LOCUS AND METHODS OF USE THEREOF
WO2022241558A1 (en) * 2021-05-18 2022-11-24 The University Of British Columbia A method for producing blood progenitor and progenitor t cells, resulting cells and methods and uses thereof

Similar Documents

Publication Publication Date Title
JP2021514185A5 (https=)
JPWO2019157597A5 (https=)
Aqmasheh et al. Effects of mesenchymal stem cell derivatives on hematopoiesis and hematopoietic stem cells
Spanholtz et al. High log-scale expansion of functional human natural killer cells from umbilical cord blood CD34-positive cells for adoptive cancer immunotherapy
Salem et al. Mesenchymal stromal cells: current understanding and clinical status
Bonnet Biology of human bone marrow stem cells
Elahi et al. Human mesenchymal stromal cells from different sources diverge in their expression of cell surface proteins and display distinct differentiation patterns
Ratajczak et al. Adult murine bone marrow-derived very small embryonic-like stem cells differentiate into the hematopoietic lineage after coculture over OP9 stromal cells
K. Batsali et al. Mesenchymal stem cells derived from Wharton's Jelly of the umbilical cord: biological properties and emerging clinical applications
Cheng et al. Human adult marrow cells support prolonged expansion of human embryonic stem cells in culture
Bauer et al. New insights into the cell biology of hematopoietic progenitors by studying prominin-1 (CD133)
JP2019528771A5 (https=)
de Pooter et al. In vitro generation of T lymphocytes from embryonic stem cell–derived prehematopoietic progenitors
Arcangeli et al. Function of Jam-B/Jam-C interaction in homing and mobilization of human and mouse hematopoietic stem and progenitor cells
Phuc et al. Isolation of three important types of stem cells from the same samples of banked umbilical cord blood
McGuckin et al. Potential for access to embryonic‐like cells from human umbilical cord blood
JP2025024025A (ja) ナチュラルキラー細胞に分化させるための培地および方法
Bissels et al. Characterization and classification of stem cells
Signore et al. Identity and ranking of colonic mesenchymal stromal cells
Lanzoni et al. Isolation of stem cell populations with trophic and immunoregulatory functions from human intestinal tissues: potential for cell therapy in inflammatory bowel disease
Cool et al. Chasing Mavericks: The quest for defining developmental waves of hematopoiesis
TW200936148A (en) Methods for co-culturing cord blood derived cells with menstrual stem cells
Pievani et al. Harnessing mesenchymal stromal cells for the engineering of human hematopoietic niches
JP2005204539A5 (https=)
Katsiani et al. Chorionic villi derived mesenchymal like stem cells and expression of embryonic stem cells markers during long-term culturing