JP2021513347A5 - - Google Patents
Info
- Publication number
- JP2021513347A5 JP2021513347A5 JP2020542884A JP2020542884A JP2021513347A5 JP 2021513347 A5 JP2021513347 A5 JP 2021513347A5 JP 2020542884 A JP2020542884 A JP 2020542884A JP 2020542884 A JP2020542884 A JP 2020542884A JP 2021513347 A5 JP2021513347 A5 JP 2021513347A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- immune
- cells
- item
- locus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023112162A JP7882812B2 (ja) | 2018-02-11 | 2023-07-07 | 非ｈｌａ制限ｔ細胞受容体およびその使用 |
| JP2025145426A JP2025172139A (ja) | 2018-02-11 | 2025-09-02 | 非ｈｌａ制限ｔ細胞受容体およびその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862629072P | 2018-02-11 | 2018-02-11 | |
| US62/629,072 | 2018-02-11 | ||
| PCT/US2019/017525 WO2019157454A1 (en) | 2018-02-11 | 2019-02-11 | Non-hla restricted t cell receptors and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023112162A Division JP7882812B2 (ja) | 2018-02-11 | 2023-07-07 | 非ｈｌａ制限ｔ細胞受容体およびその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021513347A JP2021513347A (ja) | 2021-05-27 |
| JP2021513347A5 true JP2021513347A5 (enExample) | 2022-02-21 |
Family
ID=67548607
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020542884A Pending JP2021513347A (ja) | 2018-02-11 | 2019-02-11 | 非ｈｌａ制限ｔ細胞受容体およびその使用 |
| JP2023112162A Active JP7882812B2 (ja) | 2018-02-11 | 2023-07-07 | 非ｈｌａ制限ｔ細胞受容体およびその使用 |
| JP2025145426A Pending JP2025172139A (ja) | 2018-02-11 | 2025-09-02 | 非ｈｌａ制限ｔ細胞受容体およびその使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023112162A Active JP7882812B2 (ja) | 2018-02-11 | 2023-07-07 | 非ｈｌａ制限ｔ細胞受容体およびその使用 |
| JP2025145426A Pending JP2025172139A (ja) | 2018-02-11 | 2025-09-02 | 非ｈｌａ制限ｔ細胞受容体およびその使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US20200368283A1 (enExample) |
| EP (1) | EP3749687A4 (enExample) |
| JP (3) | JP2021513347A (enExample) |
| KR (1) | KR102828999B1 (enExample) |
| CN (1) | CN111886243A (enExample) |
| AU (2) | AU2019216982B2 (enExample) |
| BR (1) | BR112020016138A2 (enExample) |
| CA (1) | CA3090791A1 (enExample) |
| IL (2) | IL314563A (enExample) |
| MX (1) | MX2020008390A (enExample) |
| SG (1) | SG11202007622SA (enExample) |
| WO (1) | WO2019157454A1 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11202007622SA (en) | 2018-02-11 | 2020-09-29 | Memorial Sloan Kettering Cancer Center | Non-hla restricted t cell receptors and uses thereof |
| US20210207174A1 (en) * | 2018-05-25 | 2021-07-08 | The Regents Of The University Of California | Genetic engineering of endogenous proteins |
| EP4110356A4 (en) * | 2020-02-28 | 2024-03-27 | Wisconsin Alumni Research Foundation | NON-VIRAL GENERATION OF CHIMERIC ANTIGEN RECEPTOR T CELLS OBTAINED BY GENE EDITING |
| JP7886313B2 (ja) | 2020-07-30 | 2026-07-07 | アンスティテュ・クリー | Ｓｏｃｓ１に欠陥のある免疫細胞 |
| CN116723861A (zh) | 2020-12-02 | 2023-09-08 | 上海复宏汉霖生物技术股份有限公司 | 抗GARP/TGFβ抗体及使用方法 |
| IL303269A (en) | 2020-12-03 | 2023-07-01 | Century Therapeutics Inc | Genetically engineered cells and uses thereof |
| US11661459B2 (en) | 2020-12-03 | 2023-05-30 | Century Therapeutics, Inc. | Artificial cell death polypeptide for chimeric antigen receptor and uses thereof |
| TW202241935A (zh) | 2020-12-18 | 2022-11-01 | 美商世紀治療股份有限公司 | 具有可調適受體專一性之嵌合抗原受體系統 |
| CN114957481A (zh) * | 2021-02-25 | 2022-08-30 | 华夏英泰（北京）生物技术有限公司 | 针对cd19和cd22的双靶点star |
| US20250352577A1 (en) | 2021-03-11 | 2025-11-20 | Mnemo Therapeutics | Tumor neoantigenic peptides and uses thereof |
| IL305804A (en) | 2021-03-11 | 2023-11-01 | Inst Curie | Transmembrane neoantigenic peptides |
| CA3212964A1 (en) | 2021-03-11 | 2022-09-15 | Mnemo Therapeutics | Tumor neoantigenic peptides |
| JP2024514974A (ja) | 2021-04-26 | 2024-04-03 | メモリアル スローン－ケタリング キャンサー センター | Ａｄｇｒｅ２及び／またはｃｌｅｃ１２ａを標的とするキメラ受容体及びその使用 |
| WO2022233956A1 (en) | 2021-05-05 | 2022-11-10 | Immatics Biotechnologies Gmbh | Antigen binding proteins specifically binding prame |
| AU2022411573A1 (en) | 2021-12-17 | 2024-06-27 | Shanghai Henlius Biologics Co., Ltd. | Anti-ox40 antibodies and methods of use |
| CN118488965A (zh) | 2021-12-17 | 2024-08-13 | 上海复宏汉霖生物技术股份有限公司 | 抗ox40抗体、多特异性抗体及其使用方法 |
| JP2025501272A (ja) | 2021-12-28 | 2025-01-17 | ムネモ・セラピューティクス | 不活性化されたｓｕｖ３９ｈ１及び改変ｔｃｒを有する免疫細胞 |
| AU2023209589A1 (en) | 2022-01-21 | 2024-08-08 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Modulation of suv39h1 expression by rnas |
| KR20240163119A (ko) | 2022-03-25 | 2024-11-18 | 상하이 헨리우스 바이오테크, 인크. | 항-msln 항체 및 사용 방법 |
| EP4279085A1 (en) | 2022-05-20 | 2023-11-22 | Mnemo Therapeutics | Compositions and methods for treating a refractory or relapsed cancer or a chronic infectious disease |
| WO2023237541A1 (en) * | 2022-06-07 | 2023-12-14 | Gadeta B.V. | Delta t-cell or gamma t-cell receptor chains or parts thereof that mediate an anti-tumour or anti-infective response |
| WO2024062138A1 (en) | 2022-09-23 | 2024-03-28 | Mnemo Therapeutics | Immune cells comprising a modified suv39h1 gene |
| WO2025125363A1 (en) | 2023-12-11 | 2025-06-19 | Institut National de la Santé et de la Recherche Médicale | Host cells engineered to bypass the cd28 co-stimulation pathway and uses thereof for inducing durable immune responses under non-inflammatory conditions |
| WO2025163107A1 (en) | 2024-02-01 | 2025-08-07 | Institut Gustave Roussy | Immune cells defective for znf217 and uses thereof |
| WO2025252855A1 (en) | 2024-06-05 | 2025-12-11 | Institut National de la Santé et de la Recherche Médicale | IL-15 MUTEINS WITH PH-DEPENDENT BINDING FOR IL-15Rbeta |
| WO2025252857A1 (en) | 2024-06-05 | 2025-12-11 | Institut National de la Santé et de la Recherche Médicale | Il-15 muteins with ph-dependent binding for il-15ralpha |
| WO2026002973A1 (en) | 2024-06-25 | 2026-01-02 | Institut National de la Santé et de la Recherche Médicale | Host immune cells engineered to overexpress a foxk1 polypeptide |
| WO2026039656A2 (en) * | 2024-08-15 | 2026-02-19 | Elysion Therapeutics, Inc. | Lysis sensing receptors and uses thereof |
| WO2026062222A1 (en) | 2024-09-20 | 2026-03-26 | Institut Curie | Novel protein isoforms and uses |
| WO2026162712A1 (en) | 2025-01-31 | 2026-08-06 | Institut National de la Santé et de la Recherche Médicale | Methods for treating solid cancers combining low thermal-induced therapy and immunotherapy |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5132405A (en) | 1987-05-21 | 1992-07-21 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
| US5091513A (en) | 1987-05-21 | 1992-02-25 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
| JPS6412935A (en) | 1987-07-02 | 1989-01-17 | Mitsubishi Electric Corp | Constant-speed travel device for vehicle |
| US5906936A (en) * | 1988-05-04 | 1999-05-25 | Yeda Research And Development Co. Ltd. | Endowing lymphocytes with antibody specificity |
| IL86278A (en) * | 1988-05-04 | 2003-06-24 | Yeda Res & Dev | Endowing cells with antibody specificity using chimeric t cell receptor |
| US5399346A (en) | 1989-06-14 | 1995-03-21 | The United States Of America As Represented By The Department Of Health And Human Services | Gene therapy |
| US5843728A (en) * | 1991-03-07 | 1998-12-01 | The General Hospital Corporation | Redirection of cellular immunity by receptor chimeras |
| US20020018783A1 (en) | 1997-03-20 | 2002-02-14 | Michel Sadelain | Fusion proteins of a single chain antibody and cd28 and uses thereof |
| US6436703B1 (en) | 2000-03-31 | 2002-08-20 | Hyseq, Inc. | Nucleic acids and polypeptides |
| US7446190B2 (en) | 2002-05-28 | 2008-11-04 | Sloan-Kettering Institute For Cancer Research | Nucleic acids encoding chimeric T cell receptors |
| US9273283B2 (en) | 2009-10-29 | 2016-03-01 | The Trustees Of Dartmouth College | Method of producing T cell receptor-deficient T cells expressing a chimeric receptor |
| JP6267644B2 (ja) | 2011-10-20 | 2018-01-24 | アメリカ合衆国 | 抗ｃｄ２２キメラ抗原受容体 |
| SG10201806573TA (en) * | 2012-05-25 | 2018-09-27 | Cellectis | Methods for engineering allogeneic and immunosuppressive resistant t cell for immunotherapy |
| RU2729401C2 (ru) | 2012-10-02 | 2020-08-06 | Мемориал Слоан-Кеттеринг Кэнсер Сентер | Композиции и способы для иммунотерапии |
| SI2932264T1 (sl) * | 2012-12-14 | 2019-05-31 | Biontech Rna Pharmaceuticals Gmbh | Novi MHC-neodvisni, s tumorjem povezani antigeni |
| AU2014235968B2 (en) | 2013-03-21 | 2018-05-24 | Ospedale San Raffaele Srl | Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases |
| TWI731535B (zh) * | 2014-03-21 | 2021-06-21 | 美商艾伯維有限公司 | 抗-egfr抗體及抗體藥物結合物 |
| KR102546296B1 (ko) * | 2014-10-31 | 2023-06-21 | 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 | 변형된 t 세포에서 유전자 발현의 변경 및 그의 용도 |
| WO2016180468A1 (en) * | 2015-05-11 | 2016-11-17 | Biontech Cell & Gene Therapies Gmbh | Claudin-18.2-specific immunoreceptors and t cell epitopes |
| EP3770168A1 (en) | 2015-05-18 | 2021-01-27 | TCR2 Therapeutics Inc. | Compositions and methods for tcr reprogramming using fusion proteins |
| TW201706300A (zh) * | 2015-05-20 | 2017-02-16 | 瑟勒提斯公司 | 用於癌症免疫療法之抗－ｇｄ３專一性嵌合抗原受體 |
| ES2803728T3 (es) * | 2015-10-05 | 2021-01-29 | Prec Biosciences Inc | Células genéticamente modificadas que comprenden un gen de región constante alfa del receptor de linfocitos T humano modificado |
| MX2018004721A (es) | 2015-10-23 | 2018-07-06 | Eureka Therapeutics Inc | Construcciones quimericas anticuerpo/receptor de celulas t y usos de las mismas. |
| JP6976960B2 (ja) * | 2015-11-27 | 2021-12-08 | カーサリクス プロプライエタリー リミテッド | 遺伝子改変された細胞およびその使用 |
| AU2016374253B2 (en) * | 2015-12-18 | 2021-10-21 | Sangamo Therapeutics, Inc. | Targeted disruption of the MHC cell receptor |
| GB201604494D0 (en) * | 2016-03-16 | 2016-04-27 | Immatics Biotechnologies Gmbh | Transfected T-Cells and T-Cell receptors for use in immunotherapy against cancers |
| KR102614675B1 (ko) * | 2016-04-15 | 2023-12-19 | 메모리얼 슬로안 케터링 캔서 센터 | 유전자이식 t 세포 및 키메라 항원 수용체 t 세포 조성물 및 관련 방법 |
| WO2017192536A1 (en) | 2016-05-02 | 2017-11-09 | University Of Kansas | Eliminating mhc restriction from the t cell receptor as a strategy for immunotherapy |
| BR112019007100A2 (pt) * | 2016-10-07 | 2019-06-25 | Tcr2 Therapeutics Inc | composições e métodos para reprogramação de receptores de célula t com o uso de proteínas de fusão |
| EP3583129B1 (en) * | 2017-02-14 | 2021-11-03 | Kite Pharma, Inc. | Cd70 binding molecules and methods of use thereof |
| US11512287B2 (en) * | 2017-06-16 | 2022-11-29 | Sangamo Therapeutics, Inc. | Targeted disruption of T cell and/or HLA receptors |
| SG11202007622SA (en) * | 2018-02-11 | 2020-09-29 | Memorial Sloan Kettering Cancer Center | Non-hla restricted t cell receptors and uses thereof |
-
2019
- 2019-02-11 SG SG11202007622SA patent/SG11202007622SA/en unknown
- 2019-02-11 MX MX2020008390A patent/MX2020008390A/es unknown
- 2019-02-11 JP JP2020542884A patent/JP2021513347A/ja active Pending
- 2019-02-11 WO PCT/US2019/017525 patent/WO2019157454A1/en not_active Ceased
- 2019-02-11 EP EP19751805.3A patent/EP3749687A4/en active Pending
- 2019-02-11 CA CA3090791A patent/CA3090791A1/en active Pending
- 2019-02-11 KR KR1020207025816A patent/KR102828999B1/ko active Active
- 2019-02-11 IL IL314563A patent/IL314563A/en unknown
- 2019-02-11 CN CN201980019097.1A patent/CN111886243A/zh active Pending
- 2019-02-11 AU AU2019216982A patent/AU2019216982B2/en active Active
- 2019-02-11 IL IL276554A patent/IL276554B2/en unknown
- 2019-02-11 BR BR112020016138-1A patent/BR112020016138A2/pt unknown
-
2020
- 2020-08-11 US US16/990,185 patent/US20200368283A1/en active Pending
- 2020-10-20 US US17/075,142 patent/US11229669B2/en active Active
-
2021
- 2021-10-19 US US17/505,515 patent/US12036244B2/en active Active
-
2023
- 2023-07-07 JP JP2023112162A patent/JP7882812B2/ja active Active
-
2024
- 2024-09-26 AU AU2024220100A patent/AU2024220100A1/en active Pending
-
2025
- 2025-09-02 JP JP2025145426A patent/JP2025172139A/ja active Pending
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