JP2021511365A5 - - Google Patents

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Publication number
JP2021511365A5
JP2021511365A5 JP2020541352A JP2020541352A JP2021511365A5 JP 2021511365 A5 JP2021511365 A5 JP 2021511365A5 JP 2020541352 A JP2020541352 A JP 2020541352A JP 2020541352 A JP2020541352 A JP 2020541352A JP 2021511365 A5 JP2021511365 A5 JP 2021511365A5
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JP
Japan
Prior art keywords
approximately
day
htp
combination pharmaceutical
dose
Prior art date
Application number
JP2020541352A
Other languages
English (en)
Japanese (ja)
Other versions
JP7758320B2 (ja
JP2021511365A (ja
JPWO2019148087A5 (https=
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Priority claimed from PCT/US2019/015391 external-priority patent/WO2019148087A1/en
Publication of JP2021511365A publication Critical patent/JP2021511365A/ja
Publication of JPWO2019148087A5 publication Critical patent/JPWO2019148087A5/ja
Publication of JP2021511365A5 publication Critical patent/JP2021511365A5/ja
Priority to JP2023119314A priority Critical patent/JP2023153871A/ja
Application granted granted Critical
Publication of JP7758320B2 publication Critical patent/JP7758320B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2020541352A 2018-01-29 2019-01-28 5-ヒドロキシトリプトファンのバイオアベイラビリティを高める組成物および方法 Active JP7758320B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023119314A JP2023153871A (ja) 2018-01-29 2023-07-21 5-ヒドロキシトリプトファンのバイオアベイラビリティを高める組成物および方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862623073P 2018-01-29 2018-01-29
US62/623,073 2018-01-29
US201862743816P 2018-10-10 2018-10-10
US62/743,816 2018-10-10
PCT/US2019/015391 WO2019148087A1 (en) 2018-01-29 2019-01-28 Compositions and methods of enhancing 5-hydroxytryptophan bioavailability

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023119314A Division JP2023153871A (ja) 2018-01-29 2023-07-21 5-ヒドロキシトリプトファンのバイオアベイラビリティを高める組成物および方法

Publications (4)

Publication Number Publication Date
JP2021511365A JP2021511365A (ja) 2021-05-06
JPWO2019148087A5 JPWO2019148087A5 (https=) 2022-01-25
JP2021511365A5 true JP2021511365A5 (https=) 2022-01-25
JP7758320B2 JP7758320B2 (ja) 2025-10-22

Family

ID=67395723

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020541352A Active JP7758320B2 (ja) 2018-01-29 2019-01-28 5-ヒドロキシトリプトファンのバイオアベイラビリティを高める組成物および方法
JP2023119314A Withdrawn JP2023153871A (ja) 2018-01-29 2023-07-21 5-ヒドロキシトリプトファンのバイオアベイラビリティを高める組成物および方法

Family Applications After (1)

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JP2023119314A Withdrawn JP2023153871A (ja) 2018-01-29 2023-07-21 5-ヒドロキシトリプトファンのバイオアベイラビリティを高める組成物および方法

Country Status (14)

Country Link
US (1) US11337963B2 (https=)
EP (1) EP3746058B1 (https=)
JP (2) JP7758320B2 (https=)
KR (2) KR20200116110A (https=)
CN (1) CN111902137A (https=)
AU (1) AU2019211458B2 (https=)
BR (1) BR112020015068A2 (https=)
ES (1) ES2948788T3 (https=)
IL (1) IL276059B2 (https=)
MX (1) MX2020007760A (https=)
MY (1) MY209656A (https=)
RU (1) RU2020125170A (https=)
SG (1) SG11202007178VA (https=)
WO (1) WO2019148087A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12409163B2 (en) * 2021-07-30 2025-09-09 Evecxia Therapeutics, Inc. Method of enhancing 5-hydroxytryptophan (5-HTP) exposure
WO2023009841A1 (en) * 2021-07-30 2023-02-02 Evecxia Therapeutics, Inc. 5-hydroxytryptophan gastroretentive dosage forms
US11779567B2 (en) 2021-10-14 2023-10-10 Evecxia Therapeutics, Inc. Method for optimizing 5-hydroxytryptamine function in the brain for therapeutic purposes
DE102022103658A1 (de) * 2022-02-16 2023-08-17 Joachim Kamprad Arzneimittelzusammensetzung enthaltend L-Tryptophan (L-Try) und L-5-Hydroxytryptophan (5-HTP) sowie einen peripheren Abbauhemmer
WO2024148354A1 (en) 2023-01-06 2024-07-11 Evecxia Therapeutics, Inc. A method of enhancing 5-hydroxytryptophan (5-htp) exposure
CN119074695A (zh) * 2024-08-29 2024-12-06 江南大学 一种可提高脑内5-ht水平的口服缓释制剂及其在改善失眠中的应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4658038A (en) 1982-10-07 1987-04-14 Research Foundation For Mental Hygiene, Inc. N-acylated 5-hydroxytryptophan amide derivatives
FR2654931B1 (fr) * 1989-11-24 1993-08-27 Trouillas Paul Compositions pharmaceutiques possedant une activite sur l'ataxie et les troubles de l'equilibre, cerebelleux ou autres, de toutes origines, comprenant l'association de l-5-hydroxytryptophane et de carbidopa.
CA2290624C (en) 1997-06-06 2006-12-05 John W. Shell Gastric-retentive oral drug dosage forms for controlled release of highly soluble drugs
US6635280B2 (en) 1997-06-06 2003-10-21 Depomed, Inc. Extending the duration of drug release within the stomach during the fed mode
US6207699B1 (en) 1999-06-18 2001-03-27 Richard Brian Rothman Pharmaceutical combinations for treating obesity and food craving
TWI312285B (en) 2001-10-25 2009-07-21 Depomed Inc Methods of treatment using a gastric retained gabapentin dosage
CA2409552A1 (en) 2001-10-25 2003-04-25 Depomed, Inc. Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract
US6723340B2 (en) 2001-10-25 2004-04-20 Depomed, Inc. Optimal polymer mixtures for gastric retentive tablets
US20060013875A1 (en) 2002-05-29 2006-01-19 Impax Laboratories, Inc. Combination immediate release controlled release levodopa/carbidopa dosage forms
AU2003293423A1 (en) 2002-12-06 2004-06-30 Xenoport, Inc. Carbidopa prodrugs and uses thereof
EP1746985A4 (en) * 2004-05-21 2010-08-11 Univ Duke METHOD FOR INCREASING THE EFFECT OF SEROTONINE RECOVERY INHIBITORS
US20070213370A1 (en) 2005-11-18 2007-09-13 H. Lundbeck A/S 5-HTP Combination Therapy
US8969400B2 (en) 2007-10-01 2015-03-03 Duke University Pharmaceutical compositions of 5-hydroxytryptophan and serotonin-enhancing compound
JP2012500221A (ja) 2008-08-15 2012-01-05 ディポメド,インコーポレイティド Cns障害の処理及び予防のための胃保持性医薬組成物
RU2012133467A (ru) * 2010-02-05 2014-02-10 Фосфейдженикс Лимитед Композиция носителя
EP2629615B1 (en) * 2010-10-22 2018-10-10 Duke University Slow-release formulations of 5-hydroxytryptophan as an adjunct to pro-serotonergic therapies
CN103554005A (zh) 2013-11-22 2014-02-05 长沙理工大学 一种左旋5-羟基色氨酸的简便合成新方法

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