JP2021507695A5 - - Google Patents
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- Publication number
- JP2021507695A5 JP2021507695A5 JP2020532690A JP2020532690A JP2021507695A5 JP 2021507695 A5 JP2021507695 A5 JP 2021507695A5 JP 2020532690 A JP2020532690 A JP 2020532690A JP 2020532690 A JP2020532690 A JP 2020532690A JP 2021507695 A5 JP2021507695 A5 JP 2021507695A5
- Authority
- JP
- Japan
- Prior art keywords
- pna
- conjugate
- group
- antibody
- specific
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023077482A JP2023113642A (ja) | 2017-12-18 | 2023-05-09 | ペプチド核酸コンジュゲート |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762599810P | 2017-12-18 | 2017-12-18 | |
| USPCT/US2017/066976 | 2017-12-18 | ||
| US62/599,810 | 2017-12-18 | ||
| PCT/US2017/066976 WO2018118759A1 (en) | 2016-12-19 | 2017-12-18 | Peptide nucleic acid conjugates |
| PCT/EP2018/065697 WO2019120635A1 (en) | 2017-12-18 | 2018-06-13 | Peptide nucleic acid conjugates |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023077482A Division JP2023113642A (ja) | 2017-12-18 | 2023-05-09 | ペプチド核酸コンジュゲート |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021507695A JP2021507695A (ja) | 2021-02-25 |
| JP2021507695A5 true JP2021507695A5 (https=) | 2021-07-26 |
| JP7727385B2 JP7727385B2 (ja) | 2025-08-21 |
Family
ID=66992513
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020532690A Active JP7727385B2 (ja) | 2017-12-18 | 2018-06-13 | ペプチド核酸コンジュゲート |
| JP2023077482A Pending JP2023113642A (ja) | 2017-12-18 | 2023-05-09 | ペプチド核酸コンジュゲート |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023077482A Pending JP2023113642A (ja) | 2017-12-18 | 2023-05-09 | ペプチド核酸コンジュゲート |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US11603388B2 (https=) |
| EP (1) | EP3727470B1 (https=) |
| JP (2) | JP7727385B2 (https=) |
| CN (1) | CN111491667A (https=) |
| WO (1) | WO2019120635A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3554556B1 (en) * | 2016-12-19 | 2022-03-09 | Ventana Medical Systems, Inc. | Peptide nucleic acid conjugates |
| JP7727385B2 (ja) * | 2017-12-18 | 2025-08-21 | ヴェンタナ メディカル システムズ， インク． | ペプチド核酸コンジュゲート |
| KR102923870B1 (ko) * | 2019-09-02 | 2026-02-06 | 주식회사 시선바이오머티리얼스 | 신규한 pna 올리고머, 이의 dna 메틸화 검출용도 및 이를 이용한 dna 메틸화 검출방법 |
| CN115177740A (zh) * | 2021-04-01 | 2022-10-14 | 安升（上海）医药科技有限公司 | 核酸自组装介导的adc药物的构建方法及应用 |
| EP4653542A1 (en) * | 2024-05-21 | 2025-11-26 | Leica Microsystems CMS GmbH | Label, marker and method for analysing a biological sample |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5595707A (en) | 1990-03-02 | 1997-01-21 | Ventana Medical Systems, Inc. | Automated biological reaction apparatus |
| US5539082A (en) | 1993-04-26 | 1996-07-23 | Nielsen; Peter E. | Peptide nucleic acids |
| US5714331A (en) | 1991-05-24 | 1998-02-03 | Buchardt, Deceased; Ole | Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility |
| US5527675A (en) | 1993-08-20 | 1996-06-18 | Millipore Corporation | Method for degradation and sequencing of polymers which sequentially eliminate terminal residues |
| DE4331012A1 (de) | 1993-09-13 | 1995-03-16 | Bayer Ag | Nukleinsäuren-bindende Oligomere mit N-Verzweigung für Therapie und Diagnostik |
| US5786571A (en) | 1997-05-09 | 1998-07-28 | Lexmark International, Inc. | Wrapped temperature sensing assembly |
| CA2320390C (en) | 1998-02-11 | 2010-06-08 | Applied Biosystems, Llc | Pna and dna conjugates and methods for preparation thereof |
| US6582962B1 (en) | 1998-02-27 | 2003-06-24 | Ventana Medical Systems, Inc. | Automated molecular pathology apparatus having independent slide heaters |
| JP3847559B2 (ja) | 1998-02-27 | 2006-11-22 | ベンタナ・メデイカル・システムズ・インコーポレーテツド | 独立スライド加熱器を有する自動化分子病理学装置 |
| US20030211630A1 (en) | 1998-02-27 | 2003-11-13 | Ventana Medical Systems, Inc. | Automated molecular pathology apparatus having independent slide heaters |
| US6670113B2 (en) | 2001-03-30 | 2003-12-30 | Nanoprobes | Enzymatic deposition and alteration of metals |
| CN100513414C (zh) | 2001-08-27 | 2009-07-15 | 杰南技术公司 | 进行抗体表达和装配的系统 |
| US7280812B2 (en) | 2003-06-06 | 2007-10-09 | Interdigital Technology Corporation | Digital baseband receiver with DC discharge and gain control circuits |
| DK1636586T3 (da) | 2003-06-24 | 2009-11-23 | Ventana Med Syst Inc | Enzymkatalyseret metaldeponering til foröget in situ-detektion af immunhistokemisker epitoper og nucleinsyresekvenser |
| US8592219B2 (en) | 2005-01-17 | 2013-11-26 | Gyros Patent Ab | Protecting agent |
| SE0400181D0 (sv) | 2004-01-29 | 2004-01-29 | Gyros Ab | Segmented porous and preloaded microscale devices |
| US7244665B2 (en) | 2004-04-29 | 2007-07-17 | Micron Technology, Inc. | Wafer edge ring structures and methods of formation |
| WO2006022639A1 (en) | 2004-07-21 | 2006-03-02 | Applera Corporation | Genetic polymorphisms associated with alzheimer's disease, methods of detection and uses thereof |
| CA2606018A1 (en) | 2005-04-28 | 2006-11-02 | Ventana Medical Systems, Inc. | Nanoparticle conjugates |
| DE602006020577D1 (de) | 2005-07-01 | 2011-04-21 | Dako Denmark As | Monomere und polymere linker zur konjugierung von biologischen molekülen und anderen stoffen |
| US20070010014A1 (en) | 2005-07-06 | 2007-01-11 | General Electric Company | Compositions and methods for enhanced delivery to target sites |
| US20070134739A1 (en) | 2005-12-12 | 2007-06-14 | Gyros Patent Ab | Microfluidic assays and microfluidic devices |
| DK2444807T3 (da) | 2006-11-01 | 2014-08-11 | Ventana Med Syst Inc | Mono- og dinitropyrazolhaptenkonjugater |
| US9371348B2 (en) * | 2006-11-27 | 2016-06-21 | The Trustees Of The University Of Pennsylvania | Photocleavable oligonucleotide and uses thereof |
| EP2167963B1 (en) | 2007-05-23 | 2019-04-17 | Ventana Medical Systems, Inc. | Polymeric carriers for immunohistochemistry and in situ hybridization |
| CN101868728A (zh) | 2007-11-21 | 2010-10-20 | 鹿特丹伊拉斯姆斯大学医疗中心 | 改进的fret探针及其应用 |
| EP2334827B1 (en) | 2008-08-22 | 2015-03-11 | Ventana Medical Systems, Inc. | Method for chromogenic detection of two or more target molecules in a single sample |
| JP5634405B2 (ja) | 2008-10-07 | 2014-12-03 | ユィロス・パテント・アクチボラグＧｙｒｏｓ Ｐａｔｅｎｔ ＡＢ | 試料中のアナライトの検出のための半逐次アッセイ |
| CA2842661C (en) | 2009-10-19 | 2016-02-23 | Ventana Medical Systems, Inc. | Imaging system and techniques |
| WO2012138955A2 (en) | 2011-04-08 | 2012-10-11 | Ly Danith H | CONFORMATIONALLY-PREORGANIZED, MiniPEG-CONTAINING GAMMA-PEPTIDE NUCLEIC ACIDS |
| CN105204152B (zh) | 2011-09-09 | 2018-10-26 | 文塔纳医疗系统公司 | 成像系统、盒和使用其的方法 |
| ES2678211T3 (es) | 2012-03-27 | 2018-08-09 | Ventana Medical Systems, Inc. | Conjugados de señalización y procedimientos de uso |
| JP6479777B2 (ja) | 2013-06-11 | 2019-03-06 | ポルタゲ ファーマシューティカルス エルティーディー． | 生物学的に活性な特異的カーゴペプチドと結合したヒト由来の細胞透過性ペプチドの構造、製造および使用 |
| ES2754177T3 (es) | 2013-06-12 | 2020-04-16 | Massachusetts Gen Hospital | Métodos para la detección multiplexada de moléculas diana y sus usos |
| EP3096796A1 (en) * | 2014-01-21 | 2016-11-30 | The United States of America, as represented by The Secretary, Department of Health and Human Services | cGAP-PNA MULTIVALENT PEPTIDE NUCLEIC ACID LIGAND DISPLAY |
| CA2935426C (en) | 2014-01-30 | 2023-07-25 | F. Hoffmann-La Roche Ag | Polyoligomer compound with biocleavable conjugates for reducing or inhibiting expression of a nucleic acid target |
| CN104031129A (zh) * | 2014-07-07 | 2014-09-10 | 玉峰惠仁生物医药科技（北京）有限公司 | 用于检测金黄色葡萄球菌和/或表皮葡萄球菌的肽核酸探针组及其试剂盒、使用方法、用途 |
| JP2018503830A (ja) | 2015-02-02 | 2018-02-08 | ツー ポア ガイズ インコーポレイテッド | バイオマーカー検出のための不安定なリンカー |
| MA42157A (fr) | 2015-04-23 | 2018-02-28 | Geron Corp | Procédés de préparation de polynucléotides à l'aide de compositions de sel cationique multivalent |
| WO2018002015A1 (en) | 2016-06-28 | 2018-01-04 | Ventana Medical Systems, Inc. | New colors for chromogenic ihc and ish staining with multi-dye quinone methide and tyramide conjugates |
| JP7727385B2 (ja) * | 2017-12-18 | 2025-08-21 | ヴェンタナ メディカル システムズ， インク． | ペプチド核酸コンジュゲート |
-
2018
- 2018-06-13 JP JP2020532690A patent/JP7727385B2/ja active Active
- 2018-06-13 WO PCT/EP2018/065697 patent/WO2019120635A1/en not_active Ceased
- 2018-06-13 CN CN201880081628.5A patent/CN111491667A/zh active Pending
- 2018-06-13 EP EP18730359.9A patent/EP3727470B1/en active Active
-
2020
- 2020-06-01 US US16/889,495 patent/US11603388B2/en active Active
-
2023
- 2023-01-30 US US18/103,381 patent/US12173031B2/en active Active
- 2023-05-09 JP JP2023077482A patent/JP2023113642A/ja active Pending
-
2024
- 2024-11-11 US US18/943,064 patent/US20250066426A1/en active Pending
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