JP2021507695A5 - - Google Patents
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- Publication number
- JP2021507695A5 JP2021507695A5 JP2020532690A JP2020532690A JP2021507695A5 JP 2021507695 A5 JP2021507695 A5 JP 2021507695A5 JP 2020532690 A JP2020532690 A JP 2020532690A JP 2020532690 A JP2020532690 A JP 2020532690A JP 2021507695 A5 JP2021507695 A5 JP 2021507695A5
- Authority
- JP
- Japan
- Prior art keywords
- pna
- conjugate
- group
- antibody
- specific
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023077482A JP2023113642A (ja) | 2017-12-18 | 2023-05-09 | ペプチド核酸コンジュゲート |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762599810P | 2017-12-18 | 2017-12-18 | |
| US62/599,810 | 2017-12-18 | ||
| USPCT/US2017/066976 | 2017-12-18 | ||
| PCT/US2017/066976 WO2018118759A1 (en) | 2016-12-19 | 2017-12-18 | Peptide nucleic acid conjugates |
| PCT/EP2018/065697 WO2019120635A1 (en) | 2017-12-18 | 2018-06-13 | Peptide nucleic acid conjugates |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023077482A Division JP2023113642A (ja) | 2017-12-18 | 2023-05-09 | ペプチド核酸コンジュゲート |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021507695A JP2021507695A (ja) | 2021-02-25 |
| JP2021507695A5 true JP2021507695A5 (enExample) | 2021-07-26 |
| JP7727385B2 JP7727385B2 (ja) | 2025-08-21 |
Family
ID=66992513
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020532690A Active JP7727385B2 (ja) | 2017-12-18 | 2018-06-13 | ペプチド核酸コンジュゲート |
| JP2023077482A Pending JP2023113642A (ja) | 2017-12-18 | 2023-05-09 | ペプチド核酸コンジュゲート |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023077482A Pending JP2023113642A (ja) | 2017-12-18 | 2023-05-09 | ペプチド核酸コンジュゲート |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US11603388B2 (enExample) |
| EP (1) | EP3727470B1 (enExample) |
| JP (2) | JP7727385B2 (enExample) |
| CN (1) | CN111491667A (enExample) |
| WO (1) | WO2019120635A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7048617B2 (ja) * | 2016-12-19 | 2022-04-05 | ヴェンタナ メディカル システムズ， インク． | ペプチド核酸コンジュゲート |
| EP3727470B1 (en) * | 2017-12-18 | 2024-11-20 | Ventana Medical Systems, Inc. | Peptide nucleic acid conjugates |
| KR102923870B1 (ko) | 2019-09-02 | 2026-02-06 | 주식회사 시선바이오머티리얼스 | 신규한 pna 올리고머, 이의 dna 메틸화 검출용도 및 이를 이용한 dna 메틸화 검출방법 |
| EP4653542A1 (en) * | 2024-05-21 | 2025-11-26 | Leica Microsystems CMS GmbH | Label, marker and method for analysing a biological sample |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5595707A (en) | 1990-03-02 | 1997-01-21 | Ventana Medical Systems, Inc. | Automated biological reaction apparatus |
| US5714331A (en) | 1991-05-24 | 1998-02-03 | Buchardt, Deceased; Ole | Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility |
| US5539082A (en) | 1993-04-26 | 1996-07-23 | Nielsen; Peter E. | Peptide nucleic acids |
| US5527675A (en) | 1993-08-20 | 1996-06-18 | Millipore Corporation | Method for degradation and sequencing of polymers which sequentially eliminate terminal residues |
| DE4331012A1 (de) | 1993-09-13 | 1995-03-16 | Bayer Ag | Nukleinsäuren-bindende Oligomere mit N-Verzweigung für Therapie und Diagnostik |
| US5786571A (en) | 1997-05-09 | 1998-07-28 | Lexmark International, Inc. | Wrapped temperature sensing assembly |
| EP1053355B1 (en) | 1998-02-11 | 2001-11-14 | PE Corporation (NY) | Pna and dna conjugates and methods for preparation thereof |
| EP2284543A3 (en) | 1998-02-27 | 2015-05-27 | Ventana Medical Systems, Inc. | System and method of aspirating and dispensing reagent |
| US6582962B1 (en) | 1998-02-27 | 2003-06-24 | Ventana Medical Systems, Inc. | Automated molecular pathology apparatus having independent slide heaters |
| US20030211630A1 (en) | 1998-02-27 | 2003-11-13 | Ventana Medical Systems, Inc. | Automated molecular pathology apparatus having independent slide heaters |
| US6670113B2 (en) | 2001-03-30 | 2003-12-30 | Nanoprobes | Enzymatic deposition and alteration of metals |
| EP1427744B1 (en) | 2001-08-27 | 2007-12-26 | Genentech, Inc. | A system for antibody expression and assembly |
| US7280812B2 (en) | 2003-06-06 | 2007-10-09 | Interdigital Technology Corporation | Digital baseband receiver with DC discharge and gain control circuits |
| ES2330441T3 (es) | 2003-06-24 | 2009-12-10 | Ventana Medical Systems, Inc. | Deposito de metal catalizado por una enzima para la deteccion in situ mejorada de epitopos inmunohistoquimicos y secuencias de acido nucleico. |
| US8592219B2 (en) | 2005-01-17 | 2013-11-26 | Gyros Patent Ab | Protecting agent |
| SE0400181D0 (sv) | 2004-01-29 | 2004-01-29 | Gyros Ab | Segmented porous and preloaded microscale devices |
| US7244665B2 (en) | 2004-04-29 | 2007-07-17 | Micron Technology, Inc. | Wafer edge ring structures and methods of formation |
| WO2006022639A1 (en) | 2004-07-21 | 2006-03-02 | Applera Corporation | Genetic polymorphisms associated with alzheimer's disease, methods of detection and uses thereof |
| WO2006116742A2 (en) | 2005-04-28 | 2006-11-02 | Ventana Medical Systems, Inc. | Fluorescent nanoparticles conjugated to antibodies via a peg linker |
| DE602006020577D1 (de) | 2005-07-01 | 2011-04-21 | Dako Denmark As | Monomere und polymere linker zur konjugierung von biologischen molekülen und anderen stoffen |
| US20070010014A1 (en) | 2005-07-06 | 2007-01-11 | General Electric Company | Compositions and methods for enhanced delivery to target sites |
| US20070134739A1 (en) | 2005-12-12 | 2007-06-14 | Gyros Patent Ab | Microfluidic assays and microfluidic devices |
| ES2905054T3 (es) | 2006-11-01 | 2022-04-06 | Ventana Med Syst Inc | Haptenos, conjugados de haptenos, composiciones de los mismos y método para su preparación y uso |
| US9371348B2 (en) * | 2006-11-27 | 2016-06-21 | The Trustees Of The University Of Pennsylvania | Photocleavable oligonucleotide and uses thereof |
| JP2010528285A (ja) | 2007-05-23 | 2010-08-19 | ベンタナ・メデイカル・システムズ・インコーポレーテツド | 免疫組織化学およびｉｎｓｉｔｕハイブリダーゼーションのためのポリマー担体 |
| BRPI0819739A2 (pt) | 2007-11-21 | 2017-05-09 | Univ Erasmus Med Ct Rotterdam | sondas de fret otimizadas e usos das mesmas |
| AU2009282760B2 (en) | 2008-08-22 | 2013-08-15 | Ventana Medical Systems, Inc. | Method for chromogenic detection of two or more target molecules in a single sample |
| JP5634405B2 (ja) | 2008-10-07 | 2014-12-03 | ユィロス・パテント・アクチボラグＧｙｒｏｓ Ｐａｔｅｎｔ ＡＢ | 試料中のアナライトの検出のための半逐次アッセイ |
| JP5627698B2 (ja) | 2009-10-19 | 2014-11-19 | ベンタナ メディカル システムズ， インコーポレイテッド | 撮像システムおよび技法 |
| US9193758B2 (en) | 2011-04-08 | 2015-11-24 | Carnegie Mellon University Center For Technology Transfer & Enterprise | Conformationally-preorganized, miniPEG-containing γ-peptide nucleic acids |
| CA2928374C (en) | 2011-09-09 | 2018-09-25 | Ventana Medical Systems, Inc. | Imaging systems, cassettes, and methods of using the same |
| CA2867144C (en) | 2012-03-27 | 2019-07-02 | Ventana Medical Systems, Inc. | Signaling conjugates and methods of use |
| ES2938758T3 (es) | 2013-06-11 | 2023-04-14 | Ppl Bvi Ltd | Proteínas de fusión que comprenden HOXD12 y dominio de unión a NEMO y su uso |
| ES2887726T3 (es) | 2013-06-12 | 2021-12-27 | Massachusetts Gen Hospital | Métodos, kits, y sistemas para la detección multiplexada de moléculas diana y sus usos |
| CN106163570A (zh) * | 2014-01-21 | 2016-11-23 | 美国卫生和人力服务部 | cGAP‑PNA多价肽核酸配体展示 |
| KR102287532B1 (ko) | 2014-01-30 | 2021-08-11 | 에프. 호프만-라 로슈 아게 | 생분해성 컨쥬게이트를 갖는 폴리 올리고머 화합물 |
| CN104031129A (zh) * | 2014-07-07 | 2014-09-10 | 玉峰惠仁生物医药科技（北京）有限公司 | 用于检测金黄色葡萄球菌和/或表皮葡萄球菌的肽核酸探针组及其试剂盒、使用方法、用途 |
| RU2712245C2 (ru) * | 2015-02-02 | 2020-01-27 | Онтера Инк. | Лабильные линкеры для выявления биомаркера |
| KR102401252B1 (ko) | 2015-04-23 | 2022-05-24 | 제론 코포레이션 | 다가 양이온 염 조성물을 사용한 폴리뉴클레오티드 제조의 방법 |
| WO2018002015A1 (en) | 2016-06-28 | 2018-01-04 | Ventana Medical Systems, Inc. | New colors for chromogenic ihc and ish staining with multi-dye quinone methide and tyramide conjugates |
| EP3727470B1 (en) * | 2017-12-18 | 2024-11-20 | Ventana Medical Systems, Inc. | Peptide nucleic acid conjugates |
-
2018
- 2018-06-13 EP EP18730359.9A patent/EP3727470B1/en active Active
- 2018-06-13 JP JP2020532690A patent/JP7727385B2/ja active Active
- 2018-06-13 CN CN201880081628.5A patent/CN111491667A/zh active Pending
- 2018-06-13 WO PCT/EP2018/065697 patent/WO2019120635A1/en not_active Ceased
-
2020
- 2020-06-01 US US16/889,495 patent/US11603388B2/en active Active
-
2023
- 2023-01-30 US US18/103,381 patent/US12173031B2/en active Active
- 2023-05-09 JP JP2023077482A patent/JP2023113642A/ja active Pending
-
2024
- 2024-11-11 US US18/943,064 patent/US20250066426A1/en active Pending
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