JP2021505295A5 - - Google Patents

Download PDF

Info

Publication number
JP2021505295A5
JP2021505295A5 JP2020531629A JP2020531629A JP2021505295A5 JP 2021505295 A5 JP2021505295 A5 JP 2021505295A5 JP 2020531629 A JP2020531629 A JP 2020531629A JP 2020531629 A JP2020531629 A JP 2020531629A JP 2021505295 A5 JP2021505295 A5 JP 2021505295A5
Authority
JP
Japan
Prior art keywords
target tissue
properties
exogenous agent
item
administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020531629A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021505295A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2018/001548 external-priority patent/WO2019116097A1/en
Publication of JP2021505295A publication Critical patent/JP2021505295A/ja
Publication of JP2021505295A5 publication Critical patent/JP2021505295A5/ja
Pending legal-status Critical Current

Links

JP2020531629A 2017-12-11 2018-12-11 微小気泡媒介超音波手技における外因性作用物質特性の制御 Pending JP2021505295A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762597076P 2017-12-11 2017-12-11
US201762597073P 2017-12-11 2017-12-11
US201762597071P 2017-12-11 2017-12-11
US62/597,073 2017-12-11
US62/597,076 2017-12-11
US62/597,071 2017-12-11
PCT/IB2018/001548 WO2019116097A1 (en) 2017-12-11 2018-12-11 Control of exogenous agent characteristics in microbubble-mediated ultrasound procedures

Publications (2)

Publication Number Publication Date
JP2021505295A JP2021505295A (ja) 2021-02-18
JP2021505295A5 true JP2021505295A5 (https=) 2021-08-19

Family

ID=65276216

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2020531574A Active JP7359765B2 (ja) 2017-12-11 2018-12-05 微小気泡強化超音波手技における治療剤の送達の制御
JP2020531576A Active JP7502185B2 (ja) 2017-12-11 2018-12-05 適応閉ループ超音波療法
JP2020531629A Pending JP2021505295A (ja) 2017-12-11 2018-12-11 微小気泡媒介超音波手技における外因性作用物質特性の制御

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP2020531574A Active JP7359765B2 (ja) 2017-12-11 2018-12-05 微小気泡強化超音波手技における治療剤の送達の制御
JP2020531576A Active JP7502185B2 (ja) 2017-12-11 2018-12-05 適応閉ループ超音波療法

Country Status (5)

Country Link
US (4) US11806496B2 (https=)
EP (3) EP3723857A1 (https=)
JP (3) JP7359765B2 (https=)
CN (5) CN111712301B (https=)
WO (3) WO2019116107A1 (https=)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10219815B2 (en) 2005-09-22 2019-03-05 The Regents Of The University Of Michigan Histotripsy for thrombolysis
CN107427695B (zh) 2015-03-09 2019-08-16 纽约州立大学研究基金会 用于组织维护、修复和再生的促进细胞活性的系统和方法
EP4230262A3 (en) 2015-06-24 2023-11-22 The Regents Of The University Of Michigan Histotripsy therapy systems for the treatment of brain tissue
US12179042B2 (en) 2017-02-23 2024-12-31 Oron Zachar Transcranial ultrasound focusing
US11123575B2 (en) 2017-06-29 2021-09-21 Insightec, Ltd. 3D conformal radiation therapy with reduced tissue stress and improved positional tolerance
CN113286552B (zh) 2018-11-28 2025-05-02 希斯托索尼克斯公司 组织摧毁术系统及方法
US20220161013A1 (en) * 2019-04-04 2022-05-26 Northwestern University Improved delivery of drug therapy to the cns by ultrasound-based opening of the blood-brain barrier
US12151125B2 (en) * 2019-06-06 2024-11-26 Insightec Ltd. Magnetic resonance (MR) performance in MR-guided ultrasound systems
WO2021011777A1 (en) * 2019-07-16 2021-01-21 Applaud Medical Inc. System and method for comminution of biomineralizations using microbubbles
CN114144228B (zh) * 2019-07-25 2024-08-30 医视特有限公司 在超声治疗期间针对动态改变的介质的偏差校正
CN114746148A (zh) 2019-10-11 2022-07-12 医视特有限公司 用于聚焦超声程序的治疗前组织敏感化
US12303187B2 (en) * 2019-11-29 2025-05-20 Canon Medical Systems Corporation Medical image processing apparatus
EP4649997A3 (en) 2019-12-18 2026-02-11 Insightec, Ltd. Adaptive single-bubble-based autofocusing and power adjustment in ultrasound procedures
WO2021155026A1 (en) 2020-01-28 2021-08-05 The Regents Of The University Of Michigan Systems and methods for histotripsy immunosensitization
WO2021176275A1 (en) 2020-03-05 2021-09-10 Insightec, Ltd. Differential prediction of aberration corrections for ultrasound therapy
AU2021282379A1 (en) * 2020-05-27 2023-02-02 Attune Neurosciences, Inc. Ultrasound systems and associated devices and methods for modulating brain activity
JP2023530477A (ja) 2020-06-18 2023-07-18 ヒストソニックス，インコーポレーテッド 組織破砕音響／患者結合システムおよび方法
CN113198117B (zh) * 2020-08-18 2023-12-22 于波 二氢卟吩衍生物与超声医疗系统的组合
EP4204084A4 (en) 2020-08-27 2024-10-09 The Regents Of The University Of Michigan ULTRASONIC TRANSDUCER WITH TRANSMIT-RECEIVE CAPABILITY FOR HISTOTRIPSY
CN113040814B (zh) * 2021-03-11 2023-12-22 飞依诺科技股份有限公司 超声微泡空化设备的成像处理方法及成像处理系统
EP4351718A4 (en) 2021-06-07 2025-03-26 The Regents of The University of Michigan MINIMALLY INVASIVE HISTOTRIPSY METHODS AND SYSTEMS
IL308943A (en) 2021-06-07 2024-01-01 Univ Michigan Regents All-inclusive ultrasound systems and methods that include histotripsy
US20250263798A1 (en) 2021-07-01 2025-08-21 Insightec Ltd. Diagnostic and treatment monitoring based on blood-brain barrier disruption
CA3232539A1 (en) * 2021-09-24 2023-03-30 Hong Chen Systems and methods for focused ultrasound-enabled liquid biopsy
CN118382482A (zh) 2021-11-12 2024-07-23 医视特有限公司 用于短脉冲过程的超声自动聚焦
JP2024545177A (ja) * 2021-12-09 2024-12-05 インサイテック リミテッド 神経学的標的へのモノクローナル抗体の効果的な送達のためのシステムおよび方法
WO2024047580A1 (en) * 2022-08-31 2024-03-07 Insightec Ltd. Enforced tissue residency of payload molecules by acoustic disruption
US20240142472A1 (en) 2022-10-24 2024-05-02 West Virginia University Board of Governors on behalf of West Virginia University Methods of improving neurodegenerative disorders by targeted delivery of therapeutic agents
AU2023366591A1 (en) 2022-10-28 2025-04-24 Histosonics, Inc. Histotripsy systems and methods
WO2024221001A2 (en) 2023-04-20 2024-10-24 Histosonics, Inc. Histotripsy systems and associated methods including user interfaces and workflows for treatment planning and therapy
CN117064445B (zh) * 2023-09-25 2026-03-27 山东第一医科大学附属肿瘤医院(山东省肿瘤防治研究院、山东省肿瘤医院) 一种低强度的聚焦超声换能器定位调控方法、装置及设备
CN120305583B (zh) * 2024-01-15 2026-01-06 北京大学 微气泡控制方法、装置、设备、介质及产品

Family Cites Families (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6740039B1 (en) * 1999-08-20 2004-05-25 Koninklijke Philips Electronics N.V. Methods and apparatus for displaying information relating to delivery and activation of a therapeutic agent using ultrasound energy
US6716168B2 (en) * 2002-04-30 2004-04-06 Siemens Medical Solutions Usa, Inc. Ultrasound drug delivery enhancement and imaging systems and methods
JP2004275850A (ja) * 2003-03-14 2004-10-07 Hitachi Ltd 超音波装置
US20080319316A1 (en) * 2005-08-30 2008-12-25 Koninklijke Philips Electronics N.V. Combination Imaging and Therapy Transducer
JP2009505769A (ja) * 2005-08-30 2009-02-12 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 治療トランスデューサ増幅器を有する、画像化及び治療トランスデューサの組合せ
JP5094723B2 (ja) * 2005-08-30 2012-12-12 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 凝血塊を溶解するために組み合わされたイメージング及び治療トランスデューサを使用する方法
US8257338B2 (en) 2006-10-27 2012-09-04 Artenga, Inc. Medical microbubble generation
CN100551440C (zh) * 2006-08-30 2009-10-21 中国人民解放军第三军医大学第二附属医院 一种用于肿瘤超声治疗的治疗型超声微泡及其制备方法
US7974682B2 (en) * 2006-11-22 2011-07-05 Marcela Gonzalez Molezzi System and method to adaptively control contrast-enhanced diagnostic imaging procedure
CN101631501B (zh) * 2007-03-09 2012-05-30 皇家飞利浦电子股份有限公司 控制由超声敏感粒子携带的材料的释放的方法
JP4279328B2 (ja) * 2007-05-07 2009-06-17 株式会社日立製作所 超音波撮像システム
US20080299177A1 (en) * 2007-06-06 2008-12-04 Biovaluation & Analysis, Inc. Supramolecular Complexes for Use in Acoustically Mediated Intracellular Drug Delivery in vivo
WO2009081339A1 (en) * 2007-12-21 2009-07-02 Koninklijke Philips Electronics, N.V. Systems and methods for tracking and guiding high intensity focused ultrasound beams
CN101244028A (zh) * 2008-02-05 2008-08-20 许川山 一种药物定位递送和定量控释系统
US20090234231A1 (en) 2008-03-13 2009-09-17 Knight Jon M Imaging Catheter With Integrated Contrast Agent Injector
US8425424B2 (en) * 2008-11-19 2013-04-23 Inightee Ltd. Closed-loop clot lysis
WO2010062854A2 (en) * 2008-11-26 2010-06-03 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona, Acting For And On Behalf Of Arizona State University Methods and compositions for using bleomycin-derivatized microbubbles
US8882672B2 (en) 2008-12-29 2014-11-11 Perseus-Biomed Inc. Method and system for tissue imaging and analysis
WO2011025893A1 (en) * 2009-08-28 2011-03-03 The Trustees Of Columbia University In The City Of New York Systems, methods, and devices for production of gas-filled microbubbles
CN101642607B (zh) * 2009-09-01 2012-11-28 西安交通大学 基于阵列换能器的低强度聚焦超声药物控释与监控装置
WO2011034892A2 (en) * 2009-09-15 2011-03-24 The Trustees Of Columbia University In The City Of New York Systems, methods, and devices for microbubbles
US8932237B2 (en) 2010-04-28 2015-01-13 Insightec, Ltd. Efficient ultrasound focusing
EP2579944B1 (en) * 2010-06-09 2018-04-04 Regents Of The University Of Minnesota Dual mode ultrasound transducer (dmut) system and method for controlling delivery of ultrasound therapy
JP2012213475A (ja) * 2011-03-31 2012-11-08 Panasonic Corp 超音波造影剤注入装置
MX345430B (es) 2011-09-28 2017-01-31 Koninklijke Philips Nv Suministro mediado automatico de ultrasonido.
CN103842020B (zh) 2011-10-05 2016-12-28 皇家飞利浦有限公司 用于超声介导的递送的化验
US10449395B2 (en) 2011-12-12 2019-10-22 Insightec, Ltd. Rib identification for transcostal focused ultrasound surgery
US10441769B2 (en) * 2012-05-04 2019-10-15 University Of Houston Targeted delivery of active agents using thermally stimulated large increase of perfusion by high intensity focused ultrasound
NL2008816C2 (en) * 2012-05-14 2013-11-18 Univ Twente Method for size-sorting microbubbles and apparatus for the same.
US20150196638A1 (en) * 2012-07-08 2015-07-16 Sunnybrook Health Sciences Centre System and method for using ultrasound-stimulated microbubble exposures to induce ceramide accumulation in endothelial and tumor cells
CN103654842A (zh) * 2012-09-19 2014-03-26 重庆融海超声医学工程研究中心有限公司 超声监控与靶向控释系统
ES2732575T3 (es) * 2012-10-12 2019-11-25 Profound Medical Inc Sonicaciones de multifoco para tratamientos de hipertermia que usan ultrasonidos enfocados guiados por resonancia magnética
JP6403689B2 (ja) * 2013-01-29 2018-10-10 インサイテック・リミテッド シミュレーションベース集束超音波治療計画
KR20140103769A (ko) * 2013-02-19 2014-08-27 삼성전자주식회사 초음파를 조사하는 방법 및 이를 이용한 초음파 장치
EP2964328B1 (en) 2013-03-06 2021-09-01 Insightec, Ltd. Frequency optimization in ultrasound treatment
CN103230648B (zh) * 2013-04-24 2016-09-14 重庆医科大学 低强度聚焦超声分子显像与治疗系统
CN103267800B (zh) * 2013-05-03 2015-08-05 西安交通大学 空化微泡高信噪比超声快速成像及动态尺寸分布估计方法
US11083836B2 (en) * 2013-11-26 2021-08-10 Jacob Agris System and method for medical fluid identification and verification
US9949722B2 (en) * 2013-12-03 2018-04-24 University Of Virginia Patent Foundation System and method for binding dynamics of targeted microbubbles
FR3025112A1 (fr) * 2014-09-02 2016-03-04 Univ Bordeaux Methode de controle d'une zone ciblee du cœur, methode d'ablation d'une zone ciblee du cœur, systemes associes
CN105214742B (zh) * 2015-10-10 2017-10-31 中国科学院深圳先进技术研究院 基于人工结构声场的微流体系统及操控微粒的方法
CN108351394B (zh) * 2015-10-15 2022-05-17 因赛泰克有限公司 用于避免对同时使用的rf系统的源自mri的干扰的系统和方法
GB201601053D0 (en) * 2016-01-20 2016-03-02 Isis Innovation Method and apparatus for generating bubbles
KR101859571B1 (ko) * 2016-07-27 2018-05-21 주식회사 루트로닉 안과용 치료장치 및 이의 제어방법
US20190151239A1 (en) * 2016-07-28 2019-05-23 Cerebral Therapeutics LLC Infusing drug solution directly into brain fluid
US11103731B2 (en) 2017-01-12 2021-08-31 Insightec, Ltd. Overcoming acoustic field and skull non-uniformities
US10575816B2 (en) * 2017-01-25 2020-03-03 Insightec, Ltd. Cavitation localization

Similar Documents

Publication Publication Date Title
JP2021505295A5 (https=)
US20240416099A1 (en) Control of exogenous agent characteristics in microbubble-mediated ultrasound procedures
CN111032157B (zh) 基于模拟的药物治疗计划
CN110662575B (zh) 选择性靶向开放血脑屏障的系统和方法
JP2021505289A5 (https=)
US20210146156A1 (en) Ultrasound frequency and microbubble size optimization in microbubble-enhanced ultrasound treatment
JP2020525168A5 (https=)
JP2020525169A5 (https=)
JP2020520718A5 (https=)
Wardlow et al. Targeted antibiotic delivery using low temperature-sensitive liposomes and magnetic resonance-guided high-intensity focused ultrasound hyperthermia
US20130096595A1 (en) Methods and systems for inducing hyperthermia
US20120029397A1 (en) Tumor treatment using ultrasound cavitation
Wood et al. The disruption of murine tumor neovasculature by low-intensity ultrasound—Comparison between 1-and 3-MHz sonication frequencies
CN111920446B (zh) 使用超声增强医学治疗的系统
Lee et al. Data‐Driven Feedback Identifies Focused Ultrasound Exposure Regimens for Improved Nanotheranostic Targeting of the Brain
Wardlow et al. High intensity focused ultrasound (HIFU) heating improves perfusion and antimicrobial efficacy in mouse Staphylococcus abscess
CN103889498B (zh) 具有关键器官保护的超声介导的递送
Kim Ultrasound-Mediated Mild Hyperthermia Strategies for Targeting Brain Cancer
Rimehaug et al. Minimally invasive beat‐by‐beat monitoring of cardiac power in normal hearts and during acute ventricular dysfunction
Patel et al. DDEL-13. Enhanced CNS delivery of therapeutic nanoparticles with focused ultrasound improves treatment efficacy in glioblastoma
Seip et al. Ultrasound and microbubble mediated Doxil delivery in a murine breast cancer model: Therapeutic efficacy dependence on tumor growth rate