JP2021504414A5 - - Google Patents

Download PDF

Info

Publication number
JP2021504414A5
JP2021504414A5 JP2020529467A JP2020529467A JP2021504414A5 JP 2021504414 A5 JP2021504414 A5 JP 2021504414A5 JP 2020529467 A JP2020529467 A JP 2020529467A JP 2020529467 A JP2020529467 A JP 2020529467A JP 2021504414 A5 JP2021504414 A5 JP 2021504414A5
Authority
JP
Japan
Prior art keywords
optionally substituted
antibody
antigen
disorder
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020529467A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021504414A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2018/063171 external-priority patent/WO2019108860A1/en
Publication of JP2021504414A publication Critical patent/JP2021504414A/ja
Publication of JP2021504414A5 publication Critical patent/JP2021504414A5/ja
Pending legal-status Critical Current

Links

JP2020529467A 2017-11-29 2018-11-29 Cd2+細胞の枯渇のための組成物および方法 Pending JP2021504414A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762592169P 2017-11-29 2017-11-29
US62/592,169 2017-11-29
PCT/US2018/063171 WO2019108860A1 (en) 2017-11-29 2018-11-29 Compositions and methods for the depletion of cd2+ cells

Publications (2)

Publication Number Publication Date
JP2021504414A JP2021504414A (ja) 2021-02-15
JP2021504414A5 true JP2021504414A5 (https=) 2022-01-11

Family

ID=66664617

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020529467A Pending JP2021504414A (ja) 2017-11-29 2018-11-29 Cd2+細胞の枯渇のための組成物および方法

Country Status (14)

Country Link
US (1) US20200368363A1 (https=)
EP (1) EP3717519A4 (https=)
JP (1) JP2021504414A (https=)
KR (1) KR20200090801A (https=)
CN (1) CN111670200A (https=)
AU (1) AU2018374282A1 (https=)
BR (1) BR112020010816A2 (https=)
CA (1) CA3082166A1 (https=)
CO (1) CO2020006855A2 (https=)
EA (1) EA202090922A1 (https=)
IL (1) IL274817A (https=)
MX (1) MX2020004806A (https=)
SG (1) SG11202004192XA (https=)
WO (1) WO2019108860A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3107378A1 (en) * 2018-07-23 2020-01-30 Magenta Therapeutics, Inc. Use of an anti-cd2 antibody drug conjugate (adc) in allogeneic cell therapy
WO2021259927A2 (en) * 2020-06-23 2021-12-30 Zelarion Malta Limited Anti-cd2 antibodies
WO2022027052A1 (en) * 2020-07-28 2022-02-03 Northwestern University Clotrimazole as a treatment for immunodeficiency disorders
JP2025517363A (ja) * 2022-05-17 2025-06-05 ザ ユーエービー リサーチ ファンデーション 炎症性皮膚障害を治療または予防するための方法及び組成物
WO2024079046A1 (en) * 2022-10-10 2024-04-18 Zelarion Malta Limited Anti-cd2 antibodies for type 1 diabetes
WO2024118559A2 (en) * 2022-11-28 2024-06-06 Icell Gene Therapeutics Inc. Engineered immune cells for treating disorders, compositions and methods thereof
TW202535955A (zh) * 2023-11-27 2025-09-16 丹麥商珍美寶股份有限公司 用於ptk7檢測之抗體及方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69428272T2 (de) * 1993-03-05 2002-06-27 Universite Catholique De Louvain, Louvair La Neuve Lo-cd2a antikörper und dessen verwendung zur inhibition von t-zell-aktivierung und -wachstum
US7592006B1 (en) * 1993-03-05 2009-09-22 Université Catholique de Louvain Composition comprising the LO-CD2a antibody
US5795572A (en) * 1993-05-25 1998-08-18 Bristol-Myers Squibb Company Monoclonal antibodies and FV specific for CD2 antigen
US6849258B1 (en) * 1997-07-18 2005-02-01 Universite Catholique De Louvain LO-CD2a antibody and uses thereof for inhibiting T cell activation and proliferation
JP4808841B2 (ja) * 1997-07-18 2011-11-02 バイオトランスプラント,インコーポレイテッド T細胞活性化および増殖を阻害するLO−CD2a抗体およびその使用法
US6558662B2 (en) * 1997-11-14 2003-05-06 The General Hospital Corporation Treatment of hematologic disorders
SI1545613T1 (sl) * 2002-07-31 2011-11-30 Seattle Genetics Inc Avristatinski konjugati in njihova uporaba za zdravljenje raka avtoimunske bolezni ali infekcijskebolezni
WO2004022097A1 (en) * 2002-09-05 2004-03-18 Medimmune, Inc. Methods of preventing or treating cell malignancies by administering cd2 antagonists
CN105377304B (zh) * 2014-03-10 2018-05-15 海德堡医药有限责任公司 鹅膏毒肽衍生物
EP3212668B1 (en) * 2014-10-31 2020-10-14 AbbVie Biotherapeutics Inc. Anti-cs1 antibodies and antibody drug conjugates
WO2015151079A2 (en) * 2015-06-20 2015-10-08 Hangzhou Dac Biotech Co, Ltd Auristatin analogues and their conjugates with cell-binding molecules
SG11202110287QA (en) * 2019-04-24 2021-10-28 Heidelberg Pharma Res Gmbh Amatoxin antibody-drug conjugates and uses thereof

Similar Documents

Publication Publication Date Title
JP2021504414A5 (https=)
JP2019522050A5 (https=)
WO2019108863A4 (en) Compositions and methods for the depletion of cd5+ cells
DK1507556T3 (en) Calicheamicin derivative-carrier conjugates
WO2019108860A4 (en) Compositions and methods for the depletion of cd2+ cells
JP2021500391A5 (https=)
DiJoseph et al. Antibody-targeted chemotherapy of B-cell lymphoma using calicheamicin conjugated to murine or humanized antibody against CD22
RU2008149918A (ru) Антитела к nkg2a и их применения
RU2012142311A (ru) Интерлейкин-13-связывающие белки
WO2018210795A1 (en) ANTI-SIRPα ANTIBODIES
RU2018130757A (ru) Конъюгаты антитела к cd74, композиции, содержащие конъюгаты антитела к cd74, и способы использования конъюгатов антитела к cd74
CA2153692A1 (en) Recombinant anti-vla4 antibody molecules
RU2010133892A (ru) Гуманизированные моноклональные антитела против человеческого nkg2a
HRP20240939T1 (hr) Anti-cd3 protutijela i metode uporabe
RU2019140602A (ru) АНТИ-GARP-TGF-β-АНТИТЕЛА
JP2006506955A5 (https=)
RU2009136913A (ru) Биспецифические связывающие агенты с межвидовой специфичностью
JP2016503067A5 (https=)
WO2013072523A4 (en) Bi-specific antibodies for medical use
IL305954A (en) Nectin-4 protein antibody and extacan compounds
CN111886023A (zh) 针对tim-3的抗体及其用途
WO2022268050A1 (zh) 一种药物组合及其用途
JP2026021532A (ja) Btla抗体
WO2008081331A2 (en) Enhancing the level of antibody expression by framework re-engineering
JPWO2021202770A5 (https=)