JP2021503003A5 - - Google Patents
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- Publication number
- JP2021503003A5 JP2021503003A5 JP2020544181A JP2020544181A JP2021503003A5 JP 2021503003 A5 JP2021503003 A5 JP 2021503003A5 JP 2020544181 A JP2020544181 A JP 2020544181A JP 2020544181 A JP2020544181 A JP 2020544181A JP 2021503003 A5 JP2021503003 A5 JP 2021503003A5
- Authority
- JP
- Japan
- Prior art keywords
- och
- formula
- chemical
- amine
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 0 *C[C@](C(*)C1*)O[C@]1[n]1c2ncnc(*)c2nc1 Chemical compound *C[C@](C(*)C1*)O[C@]1[n]1c2ncnc(*)c2nc1 0.000 description 4
- VOPWYDLUZFPJNL-UHFFFAOYSA-N Cc1ncnc2c1nc[n]2C Chemical compound Cc1ncnc2c1nc[n]2C VOPWYDLUZFPJNL-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1718804.6A GB201718804D0 (en) | 2017-11-14 | 2017-11-14 | Novel use |
| GB1718804.6 | 2017-11-14 | ||
| PCT/GB2018/053305 WO2019097233A1 (en) | 2017-11-14 | 2018-11-14 | Nucleotide derivatives containing amine masked moieties and their use in a templated and non-templated enzymatic nucleic acid synthesis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021503003A JP2021503003A (ja) | 2021-02-04 |
| JP2021503003A5 true JP2021503003A5 (https=) | 2021-12-16 |
Family
ID=60788377
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020544181A Pending JP2021503003A (ja) | 2017-11-14 | 2018-11-14 | アミン保護された部分を含むヌクレオチド誘導体、並びに鋳型依存性及び鋳型非依存性酵素的核酸合成におけるそれらの使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US11505815B2 (https=) |
| EP (1) | EP3710461A1 (https=) |
| JP (1) | JP2021503003A (https=) |
| CN (1) | CN111344296A (https=) |
| AU (1) | AU2018366391A1 (https=) |
| CA (1) | CA3082429A1 (https=) |
| GB (2) | GB201718804D0 (https=) |
| WO (1) | WO2019097233A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2019311199B2 (en) | 2018-07-23 | 2024-12-19 | Dna Script | Massively parallel enzymatic synthesis of nucleic acid strands |
| SG11202105441WA (en) | 2018-12-13 | 2021-06-29 | Dna Script | Direct oligonucleotide synthesis on cells and biomolecules |
| SG11202107921SA (en) | 2019-02-12 | 2021-08-30 | Dna Script | Efficient product cleavage in template-free enzymatic synthesis of polynucleotides. |
| WO2020165334A1 (en) * | 2019-02-14 | 2020-08-20 | Dna Script | Process for preparing 3'-o-amino-ribonucleotide |
| GB201906772D0 (en) * | 2019-05-14 | 2019-06-26 | Nuclera Nucleics Ltd | Nucleic acid polymer with amine-masked bases |
| EP4126895A1 (en) * | 2020-03-30 | 2023-02-08 | DNA Script | Method for preparing 3'-o-amino-2'-deoxyribonucleoside-5'-triphosphates |
| EP4132941A2 (en) * | 2020-04-06 | 2023-02-15 | Nuclera Nucleics Ltd | 3'-aminooxy-c5-substituted cytosine nucleotide derivatives and their use in a templated and non-templated enzymatic nucleic acid synthesis |
| GB202005043D0 (en) * | 2020-04-06 | 2020-05-20 | Nuclera Nucleics Ltd | C5-modified Thymidines |
| US11850258B1 (en) * | 2020-05-29 | 2023-12-26 | Nilesh B. Karalkar | Ribonucleoside derivatives with 3′-aminoxy groups |
| WO2024227846A2 (en) | 2023-05-03 | 2024-11-07 | Dna Script | Reagent used in deprotection of 3'-o-amino polynucleotides |
| CN116949152B (zh) * | 2023-06-16 | 2025-03-11 | 广州国家实验室 | 一种单碱基水平检测基因组DNA上N4-mC及5mC修饰的测序方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3022967B2 (ja) * | 1985-03-15 | 2000-03-21 | アンチバイラルズ インコーポレイテッド | 立体規則性ポリヌクレオチド結合ポリマー |
| US4672111A (en) * | 1985-04-23 | 1987-06-09 | University Of Wyoming | 5-azido-deoxyuridine compounds and method of synthesis of the same |
| DE3739366A1 (de) * | 1987-04-10 | 1988-10-27 | Boehringer Mannheim Gmbh | Desaza-purin-nucleosid-derivate, verfahren zu deren herstellung sowie deren verwendung bei der nucleinsaeure-sequenzierung sowie als antivirale mittel |
| JPH11512397A (ja) * | 1995-09-07 | 1999-10-26 | ユニバーシティー オブ ジョージア リサーチ ファウンデーション，インコーポレイテッド | 治療用アジド化合物 |
| IT1377936B1 (it) | 2007-03-28 | 2010-07-30 | Nucleotidi piridinici acitali, loro reparazione ed uso | |
| JP2011520845A (ja) * | 2008-05-15 | 2011-07-21 | カソリック ユニヴェルシテイト ルーヴェン，ケー．ユー． ルーヴェン アール アンド ディー | 抗癌剤の組合せによる治療 |
| US8034923B1 (en) * | 2009-03-27 | 2011-10-11 | Steven Albert Benner | Reagents for reversibly terminating primer extension |
| US9309569B2 (en) * | 2010-08-26 | 2016-04-12 | Intelligent Bio-Systems, Inc. | Methods and compositions for sequencing nucleic acid using charge |
| KR101794970B1 (ko) * | 2010-11-12 | 2017-11-07 | (주)비씨월드제약 | 신규한 뉴클레오시드 유도체 |
| KR101093787B1 (ko) * | 2011-06-10 | 2011-12-19 | (주)비씨월드제약 | 신규한 뉴클레오시드 유도체를 포함하는 암 치료용 약학적 조성물 |
| GB201502152D0 (en) * | 2015-02-10 | 2015-03-25 | Nuclera Nucleics Ltd | Novel use |
| WO2017087887A1 (en) * | 2015-11-18 | 2017-05-26 | The Trustees Of Columbia University In The City Of New York | Ion sensor dna and rna sequencing by synthesis using nucleotide reversible terminators |
-
2017
- 2017-11-14 GB GBGB1718804.6A patent/GB201718804D0/en not_active Ceased
-
2018
- 2018-11-14 CN CN201880073408.8A patent/CN111344296A/zh active Pending
- 2018-11-14 US US16/191,109 patent/US11505815B2/en active Active
- 2018-11-14 GB GB1818605.6A patent/GB2568397A/en not_active Withdrawn
- 2018-11-14 JP JP2020544181A patent/JP2021503003A/ja active Pending
- 2018-11-14 CA CA3082429A patent/CA3082429A1/en active Pending
- 2018-11-14 EP EP18811609.9A patent/EP3710461A1/en not_active Withdrawn
- 2018-11-14 WO PCT/GB2018/053305 patent/WO2019097233A1/en not_active Ceased
- 2018-11-14 AU AU2018366391A patent/AU2018366391A1/en not_active Abandoned
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