JP2021502978A5 - - Google Patents
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- JP2021502978A5 JP2021502978A5 JP2020526473A JP2020526473A JP2021502978A5 JP 2021502978 A5 JP2021502978 A5 JP 2021502978A5 JP 2020526473 A JP2020526473 A JP 2020526473A JP 2020526473 A JP2020526473 A JP 2020526473A JP 2021502978 A5 JP2021502978 A5 JP 2021502978A5
- Authority
- JP
- Japan
- Prior art keywords
- adeno
- associated virus
- virus vector
- human
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023121924A JP7615238B2 (ja) | 2017-11-15 | 2023-07-26 | 網膜ジストロフィーを治療するｒｄｈ１２コード領域を含むウイルスベクターおよび方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762586624P | 2017-11-15 | 2017-11-15 | |
| US62/586,624 | 2017-11-15 | ||
| PCT/US2018/061319 WO2019099696A1 (en) | 2017-11-15 | 2018-11-15 | Viral vectors comprising rdh12 coding regions and methods of treating retinal dystrophies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023121924A Division JP7615238B2 (ja) | 2017-11-15 | 2023-07-26 | 網膜ジストロフィーを治療するｒｄｈ１２コード領域を含むウイルスベクターおよび方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021502978A JP2021502978A (ja) | 2021-02-04 |
| JP2021502978A5 true JP2021502978A5 (enExample) | 2021-12-23 |
Family
ID=66431192
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020526473A Pending JP2021502978A (ja) | 2017-11-15 | 2018-11-15 | 網膜ジストロフィーを治療するｒｄｈ１２コード領域を含むウイルスベクターおよび方法 |
| JP2023121924A Active JP7615238B2 (ja) | 2017-11-15 | 2023-07-26 | 網膜ジストロフィーを治療するｒｄｈ１２コード領域を含むウイルスベクターおよび方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023121924A Active JP7615238B2 (ja) | 2017-11-15 | 2023-07-26 | 網膜ジストロフィーを治療するｒｄｈ１２コード領域を含むウイルスベクターおよび方法 |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US20190142909A1 (enExample) |
| EP (2) | EP3710590B1 (enExample) |
| JP (2) | JP2021502978A (enExample) |
| KR (1) | KR102704296B1 (enExample) |
| CN (2) | CN117752822A (enExample) |
| AU (1) | AU2018367606B2 (enExample) |
| BR (1) | BR112020009828A2 (enExample) |
| DK (1) | DK3710590T3 (enExample) |
| EA (1) | EA202091194A1 (enExample) |
| ES (1) | ES2983990T3 (enExample) |
| FI (1) | FI3710590T3 (enExample) |
| HR (1) | HRP20241073T1 (enExample) |
| HU (1) | HUE068393T2 (enExample) |
| IL (2) | IL274609B2 (enExample) |
| LT (1) | LT3710590T (enExample) |
| MA (1) | MA50914A (enExample) |
| MX (1) | MX2020005008A (enExample) |
| MY (1) | MY204271A (enExample) |
| PH (1) | PH12020551319A1 (enExample) |
| PL (1) | PL3710590T3 (enExample) |
| PT (1) | PT3710590T (enExample) |
| RS (1) | RS65881B1 (enExample) |
| SG (1) | SG11202004527YA (enExample) |
| SI (1) | SI3710590T1 (enExample) |
| SM (1) | SMT202400321T1 (enExample) |
| WO (1) | WO2019099696A1 (enExample) |
| ZA (1) | ZA202003416B (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102526506B1 (ko) | 2016-07-08 | 2023-05-03 | 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 | Rdh12가 연루된 장애 및 질환의 치료를 위한 방법 및 조성물 |
| EP4329882A4 (en) * | 2021-04-27 | 2025-02-26 | The Trustees of Columbia University in the City of New York | METHODS AND COMPOSITIONS FOR REGULATING CHOLESTEROL EFFLUX TO PREVENT, TREAT OR CURE MACULAR DEGENERATION |
| CN115725659A (zh) * | 2022-04-01 | 2023-03-03 | 首都医科大学附属北京同仁医院 | 一种应用视网膜原位基因编辑制作非人灵长类动物先天性黑矇模型的方法 |
| CN118453915A (zh) * | 2024-04-29 | 2024-08-09 | 中国医学科学院北京协和医院 | 一种针对rdh12突变的基因治疗药物 |
| CN119432856B (zh) * | 2024-12-30 | 2025-08-12 | 云舟生物科技(广州)股份有限公司 | 核酸分子、病毒颗粒及其制备方法和应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120172419A1 (en) * | 2009-09-15 | 2012-07-05 | Medical College Of Wisconsin Research Foundation Inc. | Reagents and methods for modulating cone photoreceptor activity |
| KR20190060881A (ko) * | 2010-04-23 | 2019-06-03 | 유니버시티 오브 플로리다 리서치 파운데이션, 인크. | 레베르 선천성 흑내장-1(lca1)의 치료를 위한 재조합 아데노-관련된 바이러스-구아닐레이트 사이클라제 조성물 및 방법 |
| WO2012167109A2 (en) * | 2011-06-03 | 2012-12-06 | Massachusetts Eye & Ear Infirmary | Rpgrip1 gene therapy for leber congenital amaurosis |
| JP6199965B2 (ja) * | 2012-07-11 | 2017-09-20 | ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | Ｒｐｇｒｘ連鎖性網膜変性のａａｖ媒介型遺伝子治療 |
| WO2015168666A2 (en) * | 2014-05-02 | 2015-11-05 | Genzyme Corporation | Aav vectors for retinal and cns gene therapy |
| GB201412011D0 (en) * | 2014-07-04 | 2014-08-20 | Ucl Business Plc | Treatments |
| PT3191139T (pt) * | 2014-07-24 | 2020-11-05 | Massachusetts Eye & Ear Infirmary | Terapia do gene rpgr para retinite pigmentosa |
| US10646588B2 (en) * | 2015-03-11 | 2020-05-12 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | RP2 and RPGR vectors for treating X-linked retinitis pigmentosa |
| EP3289080B1 (en) * | 2015-04-30 | 2021-08-25 | The Trustees of Columbia University in the City of New York | Gene therapy for autosomal dominant diseases |
| KR102526506B1 (ko) | 2016-07-08 | 2023-05-03 | 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 | Rdh12가 연루된 장애 및 질환의 치료를 위한 방법 및 조성물 |
-
2018
- 2018-11-15 WO PCT/US2018/061319 patent/WO2019099696A1/en not_active Ceased
- 2018-11-15 EP EP18878835.0A patent/EP3710590B1/en active Active
- 2018-11-15 JP JP2020526473A patent/JP2021502978A/ja active Pending
- 2018-11-15 DK DK18878835.0T patent/DK3710590T3/da active
- 2018-11-15 KR KR1020207016694A patent/KR102704296B1/ko active Active
- 2018-11-15 MX MX2020005008A patent/MX2020005008A/es unknown
- 2018-11-15 CN CN202311261068.0A patent/CN117752822A/zh active Pending
- 2018-11-15 SG SG11202004527YA patent/SG11202004527YA/en unknown
- 2018-11-15 HU HUE18878835A patent/HUE068393T2/hu unknown
- 2018-11-15 IL IL274609A patent/IL274609B2/en unknown
- 2018-11-15 EA EA202091194A patent/EA202091194A1/ru unknown
- 2018-11-15 ES ES18878835T patent/ES2983990T3/es active Active
- 2018-11-15 EP EP24163209.0A patent/EP4364803A3/en active Pending
- 2018-11-15 RS RS20240857A patent/RS65881B1/sr unknown
- 2018-11-15 LT LTEPPCT/US2018/061319T patent/LT3710590T/lt unknown
- 2018-11-15 SM SM20240321T patent/SMT202400321T1/it unknown
- 2018-11-15 MY MYPI2020002341A patent/MY204271A/en unknown
- 2018-11-15 PT PT188788350T patent/PT3710590T/pt unknown
- 2018-11-15 FI FIEP18878835.0T patent/FI3710590T3/fi active
- 2018-11-15 AU AU2018367606A patent/AU2018367606B2/en active Active
- 2018-11-15 BR BR112020009828-0A patent/BR112020009828A2/pt unknown
- 2018-11-15 IL IL308645A patent/IL308645B2/en unknown
- 2018-11-15 MA MA050914A patent/MA50914A/fr unknown
- 2018-11-15 CN CN201880086649.6A patent/CN111886340A/zh active Pending
- 2018-11-15 HR HRP20241073TT patent/HRP20241073T1/hr unknown
- 2018-11-15 US US16/192,382 patent/US20190142909A1/en not_active Abandoned
- 2018-11-15 PL PL18878835.0T patent/PL3710590T3/pl unknown
- 2018-11-15 SI SI201831135T patent/SI3710590T1/sl unknown
-
2020
- 2020-05-15 PH PH12020551319A patent/PH12020551319A1/en unknown
- 2020-06-08 ZA ZA2020/03416A patent/ZA202003416B/en unknown
-
2022
- 2022-08-09 US US17/818,623 patent/US20230190884A1/en active Pending
-
2023
- 2023-07-26 JP JP2023121924A patent/JP7615238B2/ja active Active
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