JP2021501611A5 - - Google Patents

Download PDF

Info

Publication number
JP2021501611A5
JP2021501611A5 JP2020544351A JP2020544351A JP2021501611A5 JP 2021501611 A5 JP2021501611 A5 JP 2021501611A5 JP 2020544351 A JP2020544351 A JP 2020544351A JP 2020544351 A JP2020544351 A JP 2020544351A JP 2021501611 A5 JP2021501611 A5 JP 2021501611A5
Authority
JP
Japan
Prior art keywords
cas12c
nucleic acid
polypeptide
guide rna
acid encoding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020544351A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021501611A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2018/058512 external-priority patent/WO2019089796A1/en
Publication of JP2021501611A publication Critical patent/JP2021501611A/ja
Publication of JP2021501611A5 publication Critical patent/JP2021501611A5/ja
Pending legal-status Critical Current

Links

JP2020544351A 2017-11-01 2018-10-31 Cas12c組成物及び使用方法 Pending JP2021501611A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762580392P 2017-11-01 2017-11-01
US62/580,392 2017-11-01
PCT/US2018/058512 WO2019089796A1 (en) 2017-11-01 2018-10-31 Cas12c compositions and methods of use

Publications (2)

Publication Number Publication Date
JP2021501611A JP2021501611A (ja) 2021-01-21
JP2021501611A5 true JP2021501611A5 (enExample) 2021-12-09

Family

ID=66332737

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020544351A Pending JP2021501611A (ja) 2017-11-01 2018-10-31 Cas12c組成物及び使用方法

Country Status (5)

Country Link
US (1) US20200339967A1 (enExample)
EP (1) EP3704254A4 (enExample)
JP (1) JP2021501611A (enExample)
GB (1) GB2582100B (enExample)
WO (1) WO2019089796A1 (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3204496A1 (en) 2014-10-10 2017-08-16 Editas Medicine, Inc. Compositions and methods for promoting homology directed repair
US10337051B2 (en) 2016-06-16 2019-07-02 The Regents Of The University Of California Methods and compositions for detecting a target RNA
JP2019532644A (ja) 2016-09-30 2019-11-14 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア Rna誘導型核酸修飾酵素及びその使用方法
CA3038982A1 (en) 2016-09-30 2018-04-05 The Regents Of The University Of California Rna-guided nucleic acid modifying enzymes and methods of use thereof
EP3555297A1 (en) 2016-12-19 2019-10-23 Editas Medicine, Inc. Assessing nuclease cleavage
WO2018129368A2 (en) 2017-01-06 2018-07-12 Editas Medicine, Inc. Methods of assessing nuclease cleavage
US11499151B2 (en) 2017-04-28 2022-11-15 Editas Medicine, Inc. Methods and systems for analyzing guide RNA molecules
CN110997908A (zh) 2017-06-09 2020-04-10 爱迪塔斯医药公司 工程化的cas9核酸酶
EP3652312A1 (en) 2017-07-14 2020-05-20 Editas Medicine, Inc. Systems and methods for targeted integration and genome editing and detection thereof using integrated priming sites
WO2019089808A1 (en) * 2017-11-01 2019-05-09 The Regents Of The University Of California Class 2 crispr/cas compositions and methods of use
WO2019089804A1 (en) 2017-11-01 2019-05-09 The Regents Of The University Of California Casy compositions and methods of use
CN117487776A (zh) 2017-11-01 2024-02-02 加利福尼亚大学董事会 Casz组合物和使用方法
AU2019291918B2 (en) 2018-06-29 2025-06-12 Editas Medicine, Inc. Synthetic guide molecules, compositions and methods relating thereto
WO2020028729A1 (en) 2018-08-01 2020-02-06 Mammoth Biosciences, Inc. Programmable nuclease compositions and methods of use thereof
EP3931313A2 (en) 2019-01-04 2022-01-05 Mammoth Biosciences, Inc. Programmable nuclease improvements and compositions and methods for nucleic acid amplification and detection
WO2021216512A1 (en) * 2020-04-20 2021-10-28 The Regents Of The University Of California Crispr systems in plants
US10894812B1 (en) 2020-09-30 2021-01-19 Alpine Roads, Inc. Recombinant milk proteins
WO2022072718A1 (en) 2020-09-30 2022-04-07 Nobell Foods, Inc. Recombinant milk proteins and food compositions comprising the same
US10947552B1 (en) 2020-09-30 2021-03-16 Alpine Roads, Inc. Recombinant fusion proteins for producing milk proteins in plants
AU2022284804A1 (en) 2021-06-01 2023-12-07 Arbor Biotechnologies, Inc. Gene editing systems comprising a crispr nuclease and uses thereof
US12435357B2 (en) 2022-12-22 2025-10-07 Kanso Diagnostics Ltd. Diagnostic device for detecting a target nucleic acid molecule in a biological sample
US20260232844A1 (en) 2023-02-15 2026-08-13 Arbor Biotechnologies, Inc. Gene editing method for inhibiting aberrant splicing in stathmin 2 (stmn2) transcript
WO2025171210A1 (en) 2024-02-09 2025-08-14 Arbor Biotechnologies, Inc. Compositions and methods for gene editing via homology-mediated end joining
WO2026015832A2 (en) 2024-07-12 2026-01-15 Arbor Biotechnologies, Inc. Reverse transcriptases and gene editing systems comprising such
WO2026015829A2 (en) 2024-07-12 2026-01-15 Arbor Biotechnologies, Inc. Small reverse transcriptases and gene editing systems comprising such
CN122382034A (zh) * 2026-06-10 2026-07-14 北京齐禾生科生物科技有限公司 一种新型TranC核酸酶及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015191693A2 (en) * 2014-06-10 2015-12-17 Massachusetts Institute Of Technology Method for gene editing
AU2016279062A1 (en) * 2015-06-18 2019-03-28 Omar O. Abudayyeh Novel CRISPR enzymes and systems

Similar Documents

Publication Publication Date Title
GB2582100A (en) CAS12C Compositions and methods of use
JP7448977B2 (ja) 組換えヒト血清アルブミンの高発現のための遺伝子工学操作された細菌の構築
CN113584060B (zh) 信号肽相关序列及其在蛋白质合成中的应用
CN108690139A (zh) 新型融合蛋白的制备及其在提高蛋白质合成的应用
WO2019041635A1 (zh) 一种细胞中内源性表达rna聚合酶的核酸构建物
CN114438055B (zh) 新型的crispr酶和系统以及应用
JP2020509751A5 (enExample)
CN107164375B (zh) 一种新型向导RNA表达盒及在CRISPR/Cas系统中的应用
JP2019511218A5 (enExample)
CN105925579A (zh) 一对特异性识别猪IGF2基因内含子的sgRNA及其编码DNA与应用
CN109929865B (zh) 基于gal4-uas系统的crispr辅助反式增强子激活基因表达的方法及其应用
JP6754697B2 (ja) セントロメアdna配列を含むベクター及びその用途
JP2026511898A (ja) マンモス特異的遺伝子変異およびそれを含む組成物
CN103626851A (zh) 一种镉离子结合多肽及其编码序列
JP6864308B2 (ja) 酢酸イソアミル高生産性、酢酸生産性低生産性かつイソアミルアルコール高生産性の醸造酵母の作出方法
TW201819631A (zh) Hspa5基因的啓動子
EP3835423A1 (en) Promotor for hspa8 gene
CN106399352A (zh) 调节目标蛋白表达的折叠因子及其应用
CN111434772A (zh) 一种基于CRISPR-Cas9技术的基因编辑系统及应用
US20080064061A1 (en) Yeast Promoter
KR20220098155A (ko) 비바이러스성 전사 활성화 도메인들 및 그와 관련된 방법들 및 이용들
EP3643779A1 (en) Method for assembling vectors with high efficiency in methanol-assimilating yeast
JP2019088191A (ja) 誘導型プロモーター
CN106047911B (zh) 构建的鲤凋亡基因、载体及其应用
CN120272434A (zh) 一种促肌细胞快速增殖基因敲入的牛原代细胞及其制备方法