JP2021501318A5 - - Google Patents

Download PDF

Info

Publication number
JP2021501318A5
JP2021501318A5 JP2020523389A JP2020523389A JP2021501318A5 JP 2021501318 A5 JP2021501318 A5 JP 2021501318A5 JP 2020523389 A JP2020523389 A JP 2020523389A JP 2020523389 A JP2020523389 A JP 2020523389A JP 2021501318 A5 JP2021501318 A5 JP 2021501318A5
Authority
JP
Japan
Prior art keywords
cells
virus
disease
markers
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020523389A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021501318A (ja
JP7430136B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2018/057850 external-priority patent/WO2019084493A1/en
Publication of JP2021501318A publication Critical patent/JP2021501318A/ja
Publication of JP2021501318A5 publication Critical patent/JP2021501318A5/ja
Application granted granted Critical
Publication of JP7430136B2 publication Critical patent/JP7430136B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2020523389A 2017-10-27 2018-10-26 疲弊したｔ細胞に関連する疾患を治療するための方法および組成物 Active JP7430136B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201762578212P 2017-10-27 2017-10-27
US201762578193P 2017-10-27 2017-10-27
US62/578,212 2017-10-27
US62/578,193 2017-10-27
US201862660754P 2018-04-20 2018-04-20
US62/660,754 2018-04-20
US201862661467P 2018-04-23 2018-04-23
US62/661,467 2018-04-23
PCT/US2018/057850 WO2019084493A1 (en) 2017-10-27 2018-10-26 METHODS AND COMPOSITIONS FOR TREATING DISEASES ASSOCIATED WITH SUSPECTED T CELLS

Publications (3)

Publication Number Publication Date
JP2021501318A JP2021501318A (ja) 2021-01-14
JP2021501318A5 true JP2021501318A5 (https=) 2021-12-09
JP7430136B2 JP7430136B2 (ja) 2024-02-09

Family

ID=66246753

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020523389A Active JP7430136B2 (ja) 2017-10-27 2018-10-26 疲弊したｔ細胞に関連する疾患を治療するための方法および組成物

Country Status (4)

Country Link
US (2) US11906511B2 (https=)
EP (1) EP3701041A4 (https=)
JP (1) JP7430136B2 (https=)
WO (1) WO2019084493A1 (https=)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD1083956S1 (en) * 2018-12-10 2025-07-15 Icahn School Of Medicine At Mount Sinai Display screen with a graphical user interface
WO2020246846A1 (ko) * 2019-06-05 2020-12-10 연세대학교 산학협력단 Tox에 기초한 면역 항암 요법에 대한 치료 반응 예측 방법
US20220257656A1 (en) * 2019-07-10 2022-08-18 National Cancer Center Specific marker for identifying t cells specifically attacking cancer cells
WO2021092224A1 (en) * 2019-11-05 2021-05-14 Cofactor Genomics, Inc. Methods and systems of processing complex data sets using artificial intelligence and deconvolution
CN111154835A (zh) * 2020-01-19 2020-05-15 广州基迪奥生物科技有限公司 一种ATAC-seq测序文库的构建方法
BR112022020156A2 (pt) * 2020-04-07 2022-11-22 Univ Health Network Composições e métodos para intensificar a ativação e atividade citolítica de células t cd8+ através do rompimento do complexo saga (spt?ada?gcn5?acetiltransferase
US12365871B2 (en) 2020-04-28 2025-07-22 Lyell Immunopharma, Inc. Methods for culturing cells
CN111748627A (zh) * 2020-07-02 2020-10-09 北京化工大学 膀胱癌耗竭型t细胞亚群、其特征基因及其应用
WO2022066945A1 (en) * 2020-09-23 2022-03-31 The Trustees Of Columbia University In The City Of New York Metabolic augmentation to promote and enhance immune response by tcf1+ t cell repopulation
CN112501292B (zh) * 2020-11-09 2022-12-02 中国人民解放军海军军医大学 cFAM210A在制备肝癌诊断或术后预测试剂盒以及药物中的应用
CN117157315A (zh) * 2021-03-03 2023-12-01 小利兰·斯坦福大学董事会 具有新型结合亲和力的多肽构建体及其用途
US20250026848A1 (en) * 2021-08-20 2025-01-23 U.S. Government As Represented By The Department Of Veterans Affairs Identification of pathogenic immune cell subsets in checkpoint inhibitor-induced myocarditis
WO2023034530A1 (en) * 2021-09-02 2023-03-09 Teon Therapeutics, Inc. Methods of improving growth and function of immune cells
WO2023060071A1 (en) * 2021-10-04 2023-04-13 H. Lee Moffitt Cancer Center And Research Institute Inc. Dna methylation signatures for predicting response to immunotherapy
US20250017961A1 (en) * 2021-10-26 2025-01-16 Universite Paris-Saclay T cell immunotherapy derived from highly functional autologous stem cell memory t cells
JP2023064788A (ja) * 2021-10-27 2023-05-12 国立大学法人京都大学 Ｔ細胞の評価方法及びｔ細胞評価用の組成物
CN115040538A (zh) * 2022-05-23 2022-09-13 重庆医科大学 人cxcr5＋cd8＋t细胞在制备治疗慢性乙型肝炎的药物中的应用
CN114752628B (zh) * 2022-05-30 2023-06-30 四川大学华西医院 C57bl/6小鼠多发性骨髓瘤模型的构建方法及应用
CN115029429B (zh) * 2022-06-02 2022-11-22 中国人民解放军总医院第五医学中心 炎症相关蛋白联合在预测art治疗敏感性中的应用
CN115040663B (zh) * 2022-06-15 2023-12-12 上海交通大学医学院附属仁济医院 溶质载体家族38成员2在制备多发性骨髓瘤治疗药物中的应用
CN115058504B (zh) * 2022-07-14 2025-07-04 广州医科大学 膀胱癌th17 cd4+t细胞亚群及其特征基因与应用
US20260077045A1 (en) * 2022-10-07 2026-03-19 Institut National de la Santé et de la Recherche Médicale Method to generate improving car-t cells
WO2024097677A1 (en) * 2022-11-01 2024-05-10 BioLegend, Inc. Analyzing per-cell co-expression of cellular constituents
CN119700985A (zh) * 2023-09-22 2025-03-28 清华大学 Bcor和Zc3h12a在预防和治疗慢性感染中的用途
CN117017991A (zh) * 2023-09-26 2023-11-10 中山大学附属第三医院 Hdac6选择性抑制剂在制备慢性乙型病毒性肝炎抗病毒治疗药物中的应用
CN118711670B (zh) * 2024-06-03 2026-04-14 东北林业大学 基于生物大数据的神经退行性疾病分类系统
CN118818055A (zh) * 2024-06-05 2024-10-22 复旦大学附属华山医院 用于筛选胶质瘤dc疫苗潜在受益人群的试剂盒及应用
CN120015309B (zh) * 2025-01-14 2025-12-12 中国人民解放军军事科学院军事医学研究院 用于急性高原反应（ams）易感性分群的装置

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2212350B1 (en) * 2007-10-26 2013-08-28 Governing Council of the University of Toronto Treating chronic viral infection by targetting TIM-3
WO2016061456A2 (en) 2014-10-17 2016-04-21 Dana-Farber Cancer Institute, Inc. Compositions and methods for identification, assessment, prevention, and treatment of t-cell exhaustion using cd39 biomarkers and modulators
WO2017075451A1 (en) 2015-10-28 2017-05-04 The Broad Institute Inc. Compositions and methods for evaluating and modulating immune responses by detecting and targeting pou2af1
JP2019512271A (ja) * 2016-03-21 2019-05-16 デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド Ｔ細胞疲弊状態特異的遺伝子発現調節因子およびその使用

Similar Documents

Publication Publication Date Title
JP2021501318A5 (https=)
US12139763B2 (en) Methods for subtyping of lung adenocarcinoma
Ekiz et al. MicroRNA-155 coordinates the immunological landscape within murine melanoma and correlates with immunity in human cancers
AU2019249422B2 (en) Methylation markers and targeted methylation probe panels
Davar et al. Neoadjuvant vidutolimod and nivolumab in high-risk resectable melanoma: A prospective phase II trial
Wang The opening of pandora's box: an emerging role of long noncoding RNA in viral infections
Fletcher et al. Intrahepatic transcriptional signature associated with response to interferon-α treatment in the woodchuck model of chronic hepatitis B
US20170349950A1 (en) T cell balance gene expression, compositions of matters and methods of use thereof
US20190144942A1 (en) Methods for identifying and modulating immune phenotypes
US20190338366A1 (en) Methods for subtyping of lung squamous cell carcinoma
WO2019079647A2 (en) IA STATISTICS FOR DEEP LEARNING AND PROBABILISTIC PROGRAMMING, ADVANCED, IN BIOSCIENCES
KR20150139537A (ko) 수지상 세포의 반응 유전자 발현, 물질의 조성물 및 이의 사용 방법
CN115427069A (zh) 减小遗传抽样中的统计偏差
US12584844B2 (en) Flow cytometry immunoprofiling of peripheral blood
Guo et al. Comprehensive analysis of m6A RNA methylation regulators and the immune microenvironment to aid immunotherapy in pancreatic cancer
US20200370132A1 (en) Robust genomic predictor of breast and lung cancer metastasis
JP2020178667A (ja) がん治療の効果および予後の予測方法および治療手段の選択方法
Burchill et al. Single-cell transcriptomic analyses of T cells in chronic HCV-infected patients dominated by DAA-induced interferon signaling changes
US20220033464A1 (en) Methods and compositons for modulations of immune response
Wei et al. Pan-cancer analysis of IFN-γ with possible immunotherapeutic significance: a verification of single-cell sequencing and bulk omics research
WO2005021745A1 (ja) 肝細胞癌に関連する遺伝子
Zheng et al. Multi-omics profiling identifies C1QA/B+ macrophages with multiple immune checkpoints associated with esophageal squamous cell carcinoma (ESCC) liver metastasis
US20220136070A1 (en) Methods and systems for characterizing tumor response to immunotherapy using an immunogenic profile
Ning et al. Key pathways involved in prostate cancer based on gene set enrichment analysis and meta analysis
Petrova et al. Interferons in Colorectal Cancer Pathogenesis and Therapy