JP2021501216A5 - - Google Patents
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- JP2021501216A5 JP2021501216A5 JP2020544112A JP2020544112A JP2021501216A5 JP 2021501216 A5 JP2021501216 A5 JP 2021501216A5 JP 2020544112 A JP2020544112 A JP 2020544112A JP 2020544112 A JP2020544112 A JP 2020544112A JP 2021501216 A5 JP2021501216 A5 JP 2021501216A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- substituted
- alkyl
- arbitrarily
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023131209A JP2023162250A (ja) | 2017-11-01 | 2023-08-10 | がんの治療のためのｎｏｘ阻害剤の使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17199601.0A EP3479843A1 (en) | 2017-11-01 | 2017-11-01 | Use of nox inhibitors for treatment of cancer |
| EP17199601.0 | 2017-11-01 | ||
| PCT/EP2018/079945 WO2019086579A1 (en) | 2017-11-01 | 2018-11-01 | Use of nox inhibitors for treatment of cancer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023131209A Division JP2023162250A (ja) | 2017-11-01 | 2023-08-10 | がんの治療のためのｎｏｘ阻害剤の使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021501216A JP2021501216A (ja) | 2021-01-14 |
| JP2021501216A5 true JP2021501216A5 (https=) | 2021-12-16 |
| JP7849141B2 JP7849141B2 (ja) | 2026-04-21 |
Family
ID=60201917
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020544112A Active JP7849141B2 (ja) | 2017-11-01 | 2018-11-01 | がんの治療のためのｎｏｘ阻害剤の使用 |
| JP2023131209A Pending JP2023162250A (ja) | 2017-11-01 | 2023-08-10 | がんの治療のためのｎｏｘ阻害剤の使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023131209A Pending JP2023162250A (ja) | 2017-11-01 | 2023-08-10 | がんの治療のためのｎｏｘ阻害剤の使用 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US12011436B2 (https=) |
| EP (2) | EP3479843A1 (https=) |
| JP (2) | JP7849141B2 (https=) |
| KR (2) | KR20200079265A (https=) |
| CN (1) | CN111344013A (https=) |
| AU (1) | AU2018359634B2 (https=) |
| BR (1) | BR112020008440A2 (https=) |
| CA (1) | CA3079991A1 (https=) |
| DK (1) | DK3703747T3 (https=) |
| ES (1) | ES3054839T3 (https=) |
| FI (1) | FI3703747T3 (https=) |
| IL (1) | IL274198B2 (https=) |
| MX (1) | MX2020004376A (https=) |
| PT (1) | PT3703747T (https=) |
| WO (1) | WO2019086579A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3628669A1 (en) | 2018-09-28 | 2020-04-01 | GenKyoTex Suisse SA | Novel compounds as nadph oxidase inhibitors |
| US12377117B2 (en) | 2019-04-01 | 2025-08-05 | Emory University | Hyaluronic acid nanoparticles comprising NADPH oxidases inhibitors and uses in treating cancer |
| CA3164134A1 (en) | 2019-12-06 | 2021-06-10 | Vertex Pharmaceuticals Incorporated | Substituted tetrahydrofurans as modulators of sodium channels |
| SI4347031T1 (sl) | 2021-06-04 | 2026-01-30 | Vertex Pharmaceuticals Incorporated | N-(hidroksialkil (hetero)aril) tetrahidrofuran karboksamidi kot modulatorji natrijevih kanalčkov |
| US11896719B2 (en) | 2022-01-24 | 2024-02-13 | Calliditas Therapeutics Ab | Pharmaceutical compositions |
| CN119096936A (zh) * | 2024-08-28 | 2024-12-10 | 南方医科大学第三附属医院（广东省骨科研究院） | 一种胆管癌足垫腘窝淋巴结自发转移动物模型的构建方法 |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3931407A (en) | 1973-03-01 | 1976-01-06 | American Hoechst Corporation | Method of treatment with and compositions containing condensed pyrroles bearing an N-phenyl substituent |
| DE3728278A1 (de) | 1986-12-17 | 1988-06-23 | Bayer Ag | Herbizide und fungizide mittel auf basis von substituierten pyrazolin-5-on derivaten |
| DE19518082A1 (de) | 1995-05-17 | 1996-11-21 | Merck Patent Gmbh | 4(-Arylaminomethylen)-2,4-dihydropyrazol-3-one |
| US5763496A (en) | 1995-11-27 | 1998-06-09 | The Research Foundation Of State University Of New York | Prevention of atherosclerosis using NADPH oxidase inhibitors |
| TW432073B (en) | 1995-12-28 | 2001-05-01 | Pfizer | Pyrazolopyridine compounds |
| WO1998037068A1 (en) | 1997-02-21 | 1998-08-27 | Bristol-Myers Squibb Company | Benzoic acid derivatives and related compounds as antiarrhythmic agents |
| IL144468A0 (en) | 2000-07-27 | 2002-05-23 | Pfizer Prod Inc | Use of growth hormone secretagogues for improvement of functional health status |
| US7902179B2 (en) | 2001-04-26 | 2011-03-08 | Ajinomoto Co., Inc. | Heterocyclic compounds |
| EP1291017A3 (en) | 2001-09-10 | 2003-07-02 | Warner-Lambert Company | Use of statins to inhibit formation of osteoclasts |
| EP1505068A4 (en) | 2002-04-23 | 2008-03-19 | Shionogi & Co | PYRAZOLO (1,5-a) PYRIMIDINE DERIVATIVE AND INHIBITOR OF NAD (P) H OXIDASE CONTAINING SAID DERIVATIVE |
| JP2006520326A (ja) | 2003-02-28 | 2006-09-07 | ハワード フローリー インスティチュート オブ エクスペリメンタル フィジオロジー アンド メディシン | 治療薬 |
| JPWO2004089412A1 (ja) | 2003-04-08 | 2006-07-06 | 三菱ウェルファーマ株式会社 | 特異的ｎａｄ（ｐ）ｈオキシダーゼ抑制剤 |
| TW200533356A (en) | 2004-02-24 | 2005-10-16 | Mitsubishi Pharma Corp | Fused pyridazine derivatives |
| AU2005294404A1 (en) | 2004-10-04 | 2006-04-20 | Myriad Genetics, Inc. | Compounds for Alzheimer's disease |
| FR2882654B1 (fr) | 2005-03-01 | 2007-04-27 | Servier Lab | Utilisation de derives de la diosmetine pour le traitement et la prevention des pathologies thrombotiques |
| US7759337B2 (en) | 2005-03-03 | 2010-07-20 | Amgen Inc. | Phthalazine compounds and methods of use |
| EP1896134A2 (en) | 2005-06-13 | 2008-03-12 | Rigel Pharmaceuticals, Inc. | Methods and compositions for treating degenerative bone disorders |
| US20070014739A1 (en) | 2005-07-14 | 2007-01-18 | Eldridge Gary R | Compositions and methods for controlling biofilms and bacterial infections |
| DE102005048897A1 (de) | 2005-10-12 | 2007-04-19 | Sanofi-Aventis Deutschland Gmbh | Diacylindazol-derivate als Inhibitoren von Lipasen und Phospholipasen |
| CA2648652A1 (en) | 2006-04-04 | 2007-10-11 | Myriad Genetics, Inc. | Compounds for diseases and disorders |
| AU2007292302A1 (en) | 2006-09-05 | 2008-03-13 | Bipar Sciences, Inc. | Methods for designing PARP inhibitors and uses thereof |
| PL2091530T3 (pl) | 2006-11-13 | 2018-01-31 | Pcb Ass Inc | Kompozycja hamująca aktywność oksydazy nadph |
| WO2008085486A1 (en) * | 2006-12-28 | 2008-07-17 | The Trustees Of The University Of Pennsylvania | Herpes simplex virus combined subunit vaccines and methods of use thereof |
| EP2002835A1 (en) | 2007-06-04 | 2008-12-17 | GenKyo Tex | Pyrazolo pyridine derivatives as NADPH oxidase inhibitors |
| EP2000176A1 (en) | 2007-06-04 | 2008-12-10 | GenKyo Tex | Tetrahydroindole derivatives as NADPH Oxidase inhibitors |
| TW200930713A (en) | 2007-12-03 | 2009-07-16 | Takeda Pharmaceutical | Nitrogen-containing heterocyclic compound and use thereof |
| US20090163452A1 (en) | 2007-12-20 | 2009-06-25 | Schwartz Janice B | Compositions and methods for lowering serum cholesterol |
| FR2929276B1 (fr) | 2008-04-01 | 2010-04-23 | Servier Lab | Nouveaux derives de diosmetine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| EP2166009A1 (en) | 2008-09-23 | 2010-03-24 | Genkyo Tex Sa | Pyrazolo pyridine derivatives as nadph oxidase inhibitors |
| EP2166010A1 (en) | 2008-09-23 | 2010-03-24 | Genkyo Tex Sa | Pyrazolo pyridine derivatives as NADPH oxidase inhibitors |
| EP2165707A1 (en) | 2008-09-23 | 2010-03-24 | Genkyo Tex Sa | Pyrazolo pyridine derivatives as NADPH oxidase inhibitors |
| EP2166008A1 (en) | 2008-09-23 | 2010-03-24 | Genkyo Tex Sa | Pyrazolo pyridine derivatives as NADPH oxidase inhibitors |
| EP2305679A1 (en) * | 2009-09-28 | 2011-04-06 | GenKyoTex SA | Pyrazoline dione derivatives as nadph oxidase inhibitors |
| CA2823974A1 (en) | 2010-01-08 | 2011-07-14 | Beth Israel Deaconess Medical Center | Methods and compositions for the treatment of migraine headaches |
| EP2361912A1 (en) | 2010-02-18 | 2011-08-31 | GenKyoTex SA | Pyrazolo piperidine derivatives as NADPH oxidase inhibitors |
| EP2361911A1 (en) | 2010-02-18 | 2011-08-31 | GenKyoTex SA | Pyrazolo piperidine derivatives as NADPH oxidase inhibitors |
| WO2012150543A1 (en) | 2011-05-02 | 2012-11-08 | Universite De Geneve | Macrocyclic lactones and use thereof |
| EP2591782A1 (en) * | 2011-11-11 | 2013-05-15 | Johann Wolfgang Goethe-Universität | Nadph oxidase 4 inhibitors and use thereof |
| EP2857399A1 (en) | 2013-10-03 | 2015-04-08 | GenKyoTex SA | Compounds useful for the treatment of PDE5 inhibitor-poorly responsive erectile dysfunction |
| EP3034500A1 (en) | 2014-12-17 | 2016-06-22 | Genkyotex Sa | Amido thiazole derivatives as NADPH oxidase inhibitors |
| US10584118B2 (en) | 2015-06-22 | 2020-03-10 | Actelion Pharmaceuticals Ltd | NADPH oxidase 4 inhibitors |
-
2017
- 2017-11-01 EP EP17199601.0A patent/EP3479843A1/en not_active Withdrawn
-
2018
- 2018-11-01 PT PT188008718T patent/PT3703747T/pt unknown
- 2018-11-01 AU AU2018359634A patent/AU2018359634B2/en active Active
- 2018-11-01 FI FIEP18800871.8T patent/FI3703747T3/fi active
- 2018-11-01 KR KR1020207014219A patent/KR20200079265A/ko not_active Ceased
- 2018-11-01 US US16/760,910 patent/US12011436B2/en active Active
- 2018-11-01 DK DK18800871.8T patent/DK3703747T3/da active
- 2018-11-01 JP JP2020544112A patent/JP7849141B2/ja active Active
- 2018-11-01 EP EP18800871.8A patent/EP3703747B1/en active Active
- 2018-11-01 BR BR112020008440-9A patent/BR112020008440A2/pt unknown
- 2018-11-01 MX MX2020004376A patent/MX2020004376A/es unknown
- 2018-11-01 CA CA3079991A patent/CA3079991A1/en active Pending
- 2018-11-01 KR KR1020257017083A patent/KR20250086790A/ko active Pending
- 2018-11-01 ES ES18800871T patent/ES3054839T3/es active Active
- 2018-11-01 WO PCT/EP2018/079945 patent/WO2019086579A1/en not_active Ceased
- 2018-11-01 CN CN201880071507.2A patent/CN111344013A/zh active Pending
-
2020
- 2020-04-23 IL IL274198A patent/IL274198B2/en unknown
-
2023
- 2023-08-10 JP JP2023131209A patent/JP2023162250A/ja active Pending
-
2024
- 2024-05-01 US US18/651,929 patent/US20240358687A1/en active Pending
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