JP2020537653A5 - - Google Patents

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Publication number
JP2020537653A5
JP2020537653A5 JP2020521451A JP2020521451A JP2020537653A5 JP 2020537653 A5 JP2020537653 A5 JP 2020537653A5 JP 2020521451 A JP2020521451 A JP 2020521451A JP 2020521451 A JP2020521451 A JP 2020521451A JP 2020537653 A5 JP2020537653 A5 JP 2020537653A5
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Japan
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nucleotides
composition
item
modified
composition according
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JP2020521451A
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Japanese (ja)
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JP7473472B2 (ja
JP2020537653A (ja
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Priority claimed from PCT/US2018/056077 external-priority patent/WO2019079294A1/en
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Priority to JP2024064086A priority Critical patent/JP2024086876A/ja
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JP2020521451A 2017-10-17 2018-10-16 アシアロ糖タンパク質受容体1の発現を阻害するためのRNAi剤および組成物 Active JP7473472B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024064086A JP2024086876A (ja) 2017-10-17 2024-04-11 アシアロ糖タンパク質受容体1の発現を阻害するためのRNAi剤および組成物

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762573206P 2017-10-17 2017-10-17
US62/573,206 2017-10-17
US201762608606P 2017-12-21 2017-12-21
US62/608,606 2017-12-21
US201862635277P 2018-02-26 2018-02-26
US62/635,277 2018-02-26
PCT/US2018/056077 WO2019079294A1 (en) 2017-10-17 2018-10-16 RNAI-BASED AGENTS AND COMPOSITIONS FOR INHIBITING ASIALOGLYCOPROTEIN RECEPTOR 1 RECEPTOR 1

Related Child Applications (1)

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JP2024064086A Division JP2024086876A (ja) 2017-10-17 2024-04-11 アシアロ糖タンパク質受容体1の発現を阻害するためのRNAi剤および組成物

Publications (3)

Publication Number Publication Date
JP2020537653A JP2020537653A (ja) 2020-12-24
JP2020537653A5 true JP2020537653A5 (https=) 2021-11-25
JP7473472B2 JP7473472B2 (ja) 2024-04-23

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ID=66173364

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020521451A Active JP7473472B2 (ja) 2017-10-17 2018-10-16 アシアロ糖タンパク質受容体1の発現を阻害するためのRNAi剤および組成物
JP2024064086A Pending JP2024086876A (ja) 2017-10-17 2024-04-11 アシアロ糖タンパク質受容体1の発現を阻害するためのRNAi剤および組成物

Family Applications After (1)

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JP2024064086A Pending JP2024086876A (ja) 2017-10-17 2024-04-11 アシアロ糖タンパク質受容体1の発現を阻害するためのRNAi剤および組成物

Country Status (9)

Country Link
US (1) US11492624B2 (https=)
EP (1) EP3697909A4 (https=)
JP (2) JP7473472B2 (https=)
CN (1) CN111212909A (https=)
AU (1) AU2018352379A1 (https=)
CA (1) CA3079413A1 (https=)
TW (1) TW201918555A (https=)
UY (1) UY37936A (https=)
WO (1) WO2019079294A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2018009853A (es) * 2016-09-02 2018-11-09 Arrowhead Pharmaceuticals Inc Ligandos de direccion.
IL302530A (en) * 2020-11-06 2023-07-01 Arbutus Biopharma Corp Targeted conjugates involving modified siRNA
CN116617390A (zh) * 2022-02-11 2023-08-22 武汉大学 Asgr1抑制剂在促进胆固醇外排和治疗非酒精性脂肪性肝病中的应用
WO2024046297A1 (zh) * 2022-09-02 2024-03-07 北京福元医药股份有限公司 抑制去唾液酸糖蛋白受体基因表达的siRNA、其缀合物和药物组合物及用途

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
NL9201440A (nl) 1992-08-11 1994-03-01 Univ Leiden Triantennaire clusterglycosiden, hun bereiding en toepassing.
DE60040274D1 (de) 1999-03-10 2008-10-30 Phogen Ltd Verabreichung von nukleinsäuren und proteinen an zellen
US8137695B2 (en) 2006-08-18 2012-03-20 Arrowhead Madison Inc. Polyconjugates for in vivo delivery of polynucleotides
CN1300312C (zh) * 2004-08-23 2007-02-14 中国人民解放军军事医学科学院放射与辐射医学研究所 靶向去唾液酸糖蛋白受体的抗乙型肝炎病毒反义寡核苷酸的结构和用途
JP2010505897A (ja) * 2006-10-11 2010-02-25 マックス−プランク−ゲゼルシャフト・ツア・フェルデルング・デア・ヴィッセンシャフテン・エー・ファオ インフルエンザターゲット
EP2295543A1 (en) * 2009-09-11 2011-03-16 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Method for the preparation of an influenza virus
DK2539451T3 (da) 2010-02-24 2016-04-04 Arrowhead Res Corp Sammensætninger til målrettet tilførsel af siRNA
US8501930B2 (en) 2010-12-17 2013-08-06 Arrowhead Madison Inc. Peptide-based in vivo siRNA delivery system
WO2013032829A1 (en) 2011-08-26 2013-03-07 Arrowhead Research Corporation Poly(vinyl ester) polymers for in vivo nucleic acid delivery
JP2015515530A (ja) 2012-04-18 2015-05-28 アローヘッド リサーチ コーポレイション インビボ核酸送達のためのポリ(アクリラート)ポリマー
CA2997444A1 (en) * 2015-09-29 2017-04-06 Amgen Inc. Asgr inhibitors for reducing cholesterol levels
JOP20160211B1 (ar) * 2015-10-01 2021-08-17 Arrowhead Pharmaceuticals Inc تراكيب وأساليب لتثبيط تعبير جيني للـ lpa
KR102515329B1 (ko) 2016-03-07 2023-03-29 애로우헤드 파마슈티컬스 인코포레이티드 치료용 화합물을 위한 표적화 리간드
UY37376A (es) * 2016-08-26 2018-03-23 Amgen Inc Construcciones de arni para inhibir expresión de asgr1 y métodos para su uso
MX2018009853A (es) 2016-09-02 2018-11-09 Arrowhead Pharmaceuticals Inc Ligandos de direccion.

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