JP2020537649A5 - - Google Patents

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JP2020537649A5
JP2020537649A5 JP2020520804A JP2020520804A JP2020537649A5 JP 2020537649 A5 JP2020537649 A5 JP 2020537649A5 JP 2020520804 A JP2020520804 A JP 2020520804A JP 2020520804 A JP2020520804 A JP 2020520804A JP 2020537649 A5 JP2020537649 A5 JP 2020537649A5
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sequence
heavy chain
variable region
chain variable
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JP2020520804A
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JP7374891B2 (ja
JP2020537649A (ja
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Priority claimed from PCT/US2018/055733 external-priority patent/WO2019075417A1/en
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Priority to JP2023183034A priority Critical patent/JP2024012366A/ja
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JP2020520804A 2017-10-14 2018-10-12 活性化可能抗cd71抗体による薬物コンジュゲート及びこの使用の方法 Active JP7374891B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023183034A JP2024012366A (ja) 2017-10-14 2023-10-25 活性化可能抗cd71抗体による薬物コンジュゲート及びこの使用の方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762572467P 2017-10-14 2017-10-14
US62/572,467 2017-10-14
PCT/US2018/055733 WO2019075417A1 (en) 2017-10-14 2018-10-12 CONJUGATES OF MEDICAMENT ANTI-CD71 ACTIVATED ANTIBODIES AND METHODS OF USE

Related Child Applications (1)

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JP2023183034A Division JP2024012366A (ja) 2017-10-14 2023-10-25 活性化可能抗cd71抗体による薬物コンジュゲート及びこの使用の方法

Publications (3)

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JP2020537649A JP2020537649A (ja) 2020-12-24
JP2020537649A5 true JP2020537649A5 (enExample) 2021-07-26
JP7374891B2 JP7374891B2 (ja) 2023-11-07

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JP2020520804A Active JP7374891B2 (ja) 2017-10-14 2018-10-12 活性化可能抗cd71抗体による薬物コンジュゲート及びこの使用の方法
JP2023183034A Pending JP2024012366A (ja) 2017-10-14 2023-10-25 活性化可能抗cd71抗体による薬物コンジュゲート及びこの使用の方法

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JP2023183034A Pending JP2024012366A (ja) 2017-10-14 2023-10-25 活性化可能抗cd71抗体による薬物コンジュゲート及びこの使用の方法

Country Status (36)

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US (3) US20190111150A1 (enExample)
EP (2) EP3691692B8 (enExample)
JP (2) JP7374891B2 (enExample)
KR (4) KR102529359B1 (enExample)
CN (1) CN111278467B (enExample)
AR (1) AR115178A1 (enExample)
AU (1) AU2018346969A1 (enExample)
BR (1) BR112020007302B1 (enExample)
CA (1) CA3077730A1 (enExample)
CL (1) CL2020000977A1 (enExample)
CO (1) CO2020005685A2 (enExample)
CR (1) CR20200206A (enExample)
CY (1) CY1123968T1 (enExample)
DK (1) DK3691692T3 (enExample)
DO (1) DOP2023000150A (enExample)
EC (1) ECSP20025198A (enExample)
ES (1) ES2864013T3 (enExample)
HR (1) HRP20210436T8 (enExample)
HU (1) HUE054037T2 (enExample)
IL (1) IL273586A (enExample)
LT (1) LT3691692T (enExample)
MA (1) MA50752B1 (enExample)
MD (1) MD3691692T2 (enExample)
MX (1) MX2020003723A (enExample)
PE (1) PE20210125A1 (enExample)
PH (1) PH12020550417A1 (enExample)
PL (1) PL3691692T3 (enExample)
PT (1) PT3691692T (enExample)
RS (1) RS61596B1 (enExample)
RU (2) RU2022111211A (enExample)
SG (1) SG11202003378WA (enExample)
SI (1) SI3691692T1 (enExample)
SM (1) SMT202100184T1 (enExample)
TW (2) TW202330039A (enExample)
UY (1) UY37931A (enExample)
WO (1) WO2019075417A1 (enExample)

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Publication number Priority date Publication date Assignee Title
US20130116404A1 (en) 2011-11-08 2013-05-09 Case Western Reserve University Targeted non-invasive imaging probes of egfr expressing cells
TWI726879B (zh) * 2015-05-04 2021-05-11 美商Cytomx生物製藥公司 抗cd71抗體類、可活化之抗cd71抗體類及使用彼等之方法
EP3635009B1 (en) 2017-06-07 2026-02-25 Regeneron Pharmaceuticals, Inc. Compositions and methods for internalizing enzymes
HUE054037T2 (hu) * 2017-10-14 2021-08-30 Abbvie Inc CD71 elleni, aktiválható antitest hatóanyag konjugátumok és eljárások alkalmazásukra
IL276464B2 (en) 2018-02-07 2026-01-01 Regeneron Pharma Methods and compositions for administering therapeutic protein
WO2019183633A1 (en) 2018-03-23 2019-09-26 Case Western Reserve Univeristy Psma targeted conjugate compounds and uses thereof
MA52626A (fr) 2018-05-17 2021-03-24 Regeneron Pharma Anticorps anti-cd63, conjugués et leurs utilisations
WO2021205358A1 (en) * 2020-04-08 2021-10-14 Janssen Biotech, Inc. Compositions and methods for blood-brain barrier delivery
MX2022011780A (es) 2020-04-09 2022-11-10 Cytomx Therapeutics Inc Composiciones que contienen anticuerpos activables.
AU2021313058A1 (en) * 2020-07-23 2023-03-30 Dyne Therapeutics, Inc. Muscle-targeting complexes and uses thereof
AU2022388735A1 (en) 2021-11-09 2024-05-30 Case Western Reserve University Psma targeted conjugate compounds and uses thereof
AU2023314808A1 (en) * 2022-07-29 2025-03-20 Regeneron Pharmaceuticals, Inc. Compositions and methods for transferrin receptor (tfr)-mediated delivery to the brain and muscle
AU2024299328A1 (en) 2023-07-21 2026-01-22 Marrow Therapeutics, Inc. Hematopoietic cell targeting conjugates and related methods
WO2025133132A1 (en) * 2023-12-20 2025-06-26 Institut National De La Sante Et De La Recherche Medicale Novel anti-tfr1 (cd71) antibodies for cancer treatment

Family Cites Families (16)

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Publication number Priority date Publication date Assignee Title
US5030719A (en) 1986-08-28 1991-07-09 Teijin Limited Cytotoxic antibody conjugates and a process for preparation thereof
US5151510A (en) 1990-04-20 1992-09-29 Applied Biosystems, Inc. Method of synethesizing sulfurized oligonucleotide analogs
EP1005870B1 (en) 1992-11-13 2009-01-21 Biogen Idec Inc. Therapeutic application of chimeric antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
US7666817B2 (en) 2005-08-31 2010-02-23 The Regents Of The University Of California Cellular libraries of peptide sequences (CLiPS) and methods of using the same
CA3128656A1 (en) 2007-08-22 2009-02-26 The Regents Of The University Of California Activatable binding polypeptides and methods of identification and use thereof
EP2224954B1 (en) * 2007-11-07 2014-01-08 Celldex Therapeutics, Inc. Antibodies that bind human dendritic and epithelial cell 205 (dec-205)
EP3543256A1 (en) 2009-01-12 2019-09-25 Cytomx Therapeutics Inc. Modified antibody compositions, methods of making and using thereof
AU2010241706B2 (en) * 2009-04-29 2015-07-09 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. ERG monoclonal antibodies
EP2427479B1 (en) 2009-05-07 2018-11-21 The Regents of The University of California Antibodies and methods of use thereof
ES2700514T3 (es) * 2011-02-01 2019-02-18 Genmab As Anticuerpos humanos y conjugados de anticuerpo-fármaco contra CD74
KR102098413B1 (ko) * 2012-01-31 2020-04-07 에스비아이 바이오테크 가부시키가이샤 항-포스포리파아제 d4 항체
WO2014026136A2 (en) 2012-08-10 2014-02-13 Cytomx Therapeutics, Inc. Protease-resistant systems for polypeptide display and methods of making and using thereof
CN103145847B (zh) * 2013-02-05 2014-05-21 浙江大学 一种抗cd20抗体-海兔毒素偶联物及其制备方法和应用
TWI726879B (zh) 2015-05-04 2021-05-11 美商Cytomx生物製藥公司 抗cd71抗體類、可活化之抗cd71抗體類及使用彼等之方法
CN106237341B (zh) * 2016-07-12 2019-07-30 浙江大学 一种抗体偶联药物及其制备方法和应用
HUE054037T2 (hu) * 2017-10-14 2021-08-30 Abbvie Inc CD71 elleni, aktiválható antitest hatóanyag konjugátumok és eljárások alkalmazásukra

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