JP2020535599A5 - - Google Patents
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- Publication number
- JP2020535599A5 JP2020535599A5 JP2020517087A JP2020517087A JP2020535599A5 JP 2020535599 A5 JP2020535599 A5 JP 2020535599A5 JP 2020517087 A JP2020517087 A JP 2020517087A JP 2020517087 A JP2020517087 A JP 2020517087A JP 2020535599 A5 JP2020535599 A5 JP 2020535599A5
- Authority
- JP
- Japan
- Prior art keywords
- ion
- mass
- intensity
- precursor
- mrm
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 150000002500 ions Chemical class 0.000 claims description 86
- 239000002243 precursor Substances 0.000 claims description 56
- 238000002552 multiple reaction monitoring Methods 0.000 claims description 54
- 230000007704 transition Effects 0.000 claims description 48
- 238000010884 ion-beam technique Methods 0.000 claims description 27
- 150000001875 compounds Chemical class 0.000 claims description 26
- 238000000034 method Methods 0.000 claims description 20
- 238000013467 fragmentation Methods 0.000 claims description 12
- 238000006062 fragmentation reaction Methods 0.000 claims description 12
- 238000005259 measurement Methods 0.000 claims description 12
- 230000000155 isotopic effect Effects 0.000 claims description 6
- 239000012634 fragment Substances 0.000 claims description 4
- 238000005040 ion trap Methods 0.000 claims description 4
- 238000004590 computer program Methods 0.000 claims description 3
- 230000001052 transient effect Effects 0.000 claims description 2
Images
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024062123A JP2024083502A (ja) | 2017-09-29 | 2024-04-08 | 同位体選択的ｍｓ／ｍｓを用いたｍｒｍピーク純度の査定 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762565140P | 2017-09-29 | 2017-09-29 | |
| US62/565,140 | 2017-09-29 | ||
| PCT/IB2018/057395 WO2019064173A1 (en) | 2017-09-29 | 2018-09-25 | EVALUATION OF PIC MRM PURITY WITH SELECTIVE MS / MS OF ISOTOPES |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024062123A Division JP2024083502A (ja) | 2017-09-29 | 2024-04-08 | 同位体選択的ｍｓ／ｍｓを用いたｍｒｍピーク純度の査定 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020535599A JP2020535599A (ja) | 2020-12-03 |
| JP2020535599A5 true JP2020535599A5 (enExample) | 2021-11-11 |
Family
ID=65901314
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020517087A Withdrawn JP2020535599A (ja) | 2017-09-29 | 2018-09-25 | 同位体選択的ｍｓ／ｍｓを用いたｍｒｍピーク純度の査定 |
| JP2024062123A Pending JP2024083502A (ja) | 2017-09-29 | 2024-04-08 | 同位体選択的ｍｓ／ｍｓを用いたｍｒｍピーク純度の査定 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024062123A Pending JP2024083502A (ja) | 2017-09-29 | 2024-04-08 | 同位体選択的ｍｓ／ｍｓを用いたｍｒｍピーク純度の査定 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US11024494B2 (enExample) |
| EP (1) | EP3688788B1 (enExample) |
| JP (2) | JP2020535599A (enExample) |
| CN (1) | CN111095477B (enExample) |
| WO (1) | WO2019064173A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3916754A1 (en) * | 2020-05-28 | 2021-12-01 | Thermo Fisher Scientific (Bremen) GmbH | Methods and apparatus for determining interference in ms scan data, filtering ions and performing mass spectrometry analysis on a sample |
| US20230393107A1 (en) * | 2020-10-30 | 2023-12-07 | Dh Technologies Development Pte. Ltd. | Compound Identification by Mass Spectrometry |
| US20240355605A1 (en) * | 2021-09-03 | 2024-10-24 | Dh Technologies Development Pte. Ltd. | Prediction of precursor charge state in dm-swath analysis |
| US20240420939A1 (en) * | 2021-11-01 | 2024-12-19 | Dh Technologies Development Pte. Ltd. | Ultra high throughput screening combined with definitive testing in a single sample preparation step |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4720254B2 (ja) * | 2005-03-31 | 2011-07-13 | 日本電気株式会社 | 分析方法、分析システム、及び分析プログラム |
| JP4821400B2 (ja) * | 2006-03-28 | 2011-11-24 | 株式会社島津製作所 | 構造解析システム |
| US8067728B2 (en) * | 2008-02-22 | 2011-11-29 | Dh Technologies Development Pte. Ltd. | Method of improving signal-to-noise for quantitation by mass spectrometry |
| US8335655B2 (en) * | 2008-05-30 | 2012-12-18 | Dh Technologies Development Pte. Ltd. | Intelligent saturation control for compound specific optimization of MRM |
| WO2012035412A2 (en) * | 2010-09-15 | 2012-03-22 | Dh Technologies Development Pte. Ltd. | Data independent acquisition of production spectra and reference spectra library matching |
| EP2715770B1 (en) * | 2011-06-03 | 2021-11-24 | DH Technologies Development Pte. Ltd. | Use of variable xic widths of tof-msms data for the determination of background interference in srm assays |
| CA2862834C (en) * | 2012-01-10 | 2020-06-16 | David B. Krizman | Srm/mrm assay for the insulin receptor protein |
| GB2525709B (en) * | 2014-02-04 | 2018-07-11 | Micromass Ltd | Optimized multiple reaction monitoring or single ion recording method |
| WO2015189605A1 (en) | 2014-06-11 | 2015-12-17 | Micromass Uk Limited | Ion profiling with a scanning quadrupole mass filter |
| WO2016125059A1 (en) * | 2015-02-05 | 2016-08-11 | Dh Technologies Development Pte. Ltd. | Interference detection and peak of interest deconvolution |
| EP3086353A1 (en) * | 2015-04-24 | 2016-10-26 | Thermo Fisher Scientific (Bremen) GmbH | A method of producing a mass spectrum |
-
2018
- 2018-09-25 JP JP2020517087A patent/JP2020535599A/ja not_active Withdrawn
- 2018-09-25 EP EP18862865.5A patent/EP3688788B1/en active Active
- 2018-09-25 WO PCT/IB2018/057395 patent/WO2019064173A1/en not_active Ceased
- 2018-09-25 US US16/646,674 patent/US11024494B2/en active Active
- 2018-09-25 CN CN201880059814.9A patent/CN111095477B/zh active Active
-
2024
- 2024-04-08 JP JP2024062123A patent/JP2024083502A/ja active Pending
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